K. Holden

发表

Inference of CRISPR Edits from Sanger Trace Data

Nicholas A. Rossi, T. Hsiau, T. Maures, 2019, bioRxiv.

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

Miguel Correa Marrero, Robyn M. Kaake, Gwendolyn M. Jang, 2020, Science.

Inhibitors of VPS34 and fatty-acid metabolism suppress SARS-CoV-2 replication

Stacie A. Chvatal, C. Basler, K. Holden, 2021, Cell Reports.

Prime editing in mice reveals the essentiality of a single base in driving tissue-specific gene expression

David R. Liu, Gregory A. Newby, S. Tsai, 2020, bioRxiv.

Controlling homology-directed repair outcomes in human stem cells with dCas9

C. Blauwendraat, Michael E. Ward, W. Skarnes, 2021, bioRxiv.

Viral E protein neutralizes BET protein-mediated post-entry antagonism of SARS-CoV-2

M. Ott, K. Holden, Jared Carlson-Stevermer, 2022, Cell reports.

Detection of Borrelia burgdorferi, Ehrlichia chaffeensis, and Anaplasma phagocytophilum in Ticks (Acari: Ixodidae) from a Coastal Region of California

K. Holden, R. Massung, Sulekha Anand, 2003, Journal of medical entomology.

Broad-spectrum CRISPR-mediated inhibition of SARS-CoV-2 variants and endemic coronaviruses in vitro

Lei S. Qi, A. Barron, D. Lewis, 2022, Nature Communications.

Coinfection with Anaplasma phagocytophilum Alters Borrelia burgdorferi Population Distribution in C3H/HeN Mice

S. Barthold, R. Lefebvre, K. Holden, 2005, Infection and Immunity.

Viral E protein neutralizes BET protein-mediated post-entry antagonism of SARS-CoV-2

M. Ott, K. Holden, Jared Carlson-Stevermer, 2022, Cell reports.

Following Antibiotic Treatment in Mice

S. Barthold, K. Holden, E. Hodžić, 2008 .

Rapid generation of precision preclinical cancer models using regulatable in vivo base editing

Bianca J. Diaz, S. Lowe, K. Holden, 2022, bioRxiv.

Inference of CRISPR Edits from Sanger Trace Data.

T. Hsiau, T. Maures, K. Waite, 2022, The CRISPR journal.

Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases

O. Abudayyeh, J. Gootenberg, Nathan Roberts, 2022, Nature Biotechnology.

Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses

N. Krogan, J. Carette, M. Ott, 2020, Cell.

Drag-and-drop genome insertion without DNA cleavage with CRISPR-directed integrases

O. Abudayyeh, J. Gootenberg, Nathan Roberts, 2021, bioRxiv.

Functional genomic screens identify human host factors for SARS-CoV-2 and common cold coronaviruses

Nevan J. Krogan, Jared Carlson-Stevermer, Mehdi Bouhaddou, 2020, bioRxiv.

Persistence of Borrelia burgdorferi following Antibiotic Treatment in Mice

S. Barthold, K. Holden, S. Feng, 2008, Antimicrobial Agents and Chemotherapy.

Co-detection of Bartonella henselae, Borrelia burgdorferi, and Anaplasma phagocytophilum in Ixodes pacificus ticks from California, USA.

B. Chomel, R. Kasten, K. Holden, 2006, Vector borne and zoonotic diseases.

Identification of DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen

M. Vignuzzi, S. Nisole, O. Schwartz, 2022, Nature Communications.

Identification of DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen

M. Vignuzzi, S. Nisole, O. Schwartz, 2021, bioRxiv.

BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2

J. Weissman, M. Vignuzzi, B. Conklin, 2021, Nature Cell Biology.

In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels

D. Weissman, M. Stoffel, A. Moor, 2021, Nature Biotechnology.

BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2

J. Weissman, M. Vignuzzi, B. Conklin, 2021, Nature cell biology.

Prime editing in mice reveals the essentiality of a single base in driving tissue-specific gene expression

Gregory A. Newby, S. Tsai, J. Miano, 2021, Genome Biology.

Sequence variation and phylogenetic history of the mouse Ahr gene.

D. Rank, Russell S. Thomas, C. Bradfield, 2002, Pharmacogenetics.

Viral E Protein Neutralizes BET Protein-Mediated Post-Entry Antagonism of SARS-CoV-2

N. Krogan, M. Ott, Danica Galonić Fujimori, 2021, bioRxiv.

Global landscape of the host response to SARS-CoV-2 variants reveals viral evolutionary trajectories

Nicholas O. Liotta, Gwendolyn M. Jang, R. Sharan, 2022, bioRxiv.

Chemically modified guide RNAs enhance CRISPR-Cas13 knockdown in human cells.

Neville E. Sanjana, G. B. Robb, H. Wessels, 2021, Cell chemical biology.

Generation of precision preclinical cancer models using regulated in vivo base editing.

Bianca J. Diaz, S. Lowe, K. Holden, 2023, Nature biotechnology.