M. Legut

发表

Multiplexed detection of proteins, transcriptomes, clonotypes and CRISPR perturbations in single cells

Neville E. Sanjana, Eleni P. Mimitou, R. Satija, 2019, Nature Methods.

Optimized Peptide–MHC Multimer Protocols for Detection and Isolation of Autoimmune T-Cells

Andrew K. Sewell, Dmitriy M. Chudakov, Ernest Choy, 2018, Front. Immunol..

Expanding the CITE-seq tool-kit: Detection of proteins, transcriptomes, clonotypes and CRISPR perturbations with multiplexing, in a single assay

Neville E. Sanjana, Eleni P. Mimitou, R. Satija, 2018, bioRxiv.

PD-1+ Polyfunctional T Cells Dominate the Periphery after Tumor-Infiltrating Lymphocyte Therapy for Cancer

M. Donia, I. Svane, S. Ott, 2017, Clinical Cancer Research.

TCR‐induced alteration of primary MHC peptide anchor residue

S. Wells, A. Sewell, B. Jakobsen, 2019, European journal of immunology.

Recurrent somatic mutations as predictors of immunotherapy response

Neville E. Sanjana, M. Imieliński, N. Sanjana, 2022, Nature Communications.

Expanding the scope of bacterial CRISPR activation with PAM-flexible dCas9 variants

Neville E. Sanjana, N. Sanjana, J. Carothers, 2022, bioRxiv.

High-Throughput Screens of PAM-Flexible Cas9 Variants for Gene Knockout and Transcriptional Modulation

Neville E. Sanjana, N. Sanjana, H. Wessels, 2020, Cell reports.

High-throughput screens of PAM-flexible Cas9 variants for gene knock-out and transcriptional modulation

Neville E. Sanjana, N. Sanjana, H. Wessels, 2020, bioRxiv.

Anacardic acid enhances the anticancer activity of liposomal mitoxantrone towards melanoma cell lines – in vitro studies

M. Legut, A. Kozubek, N. Filipczak, 2014, International journal of nanomedicine.

Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells

Silva Kasela, Neville E. Sanjana, Peter Smibert, 2020, Cell.

Targeting the T cell receptor β-chain constant region for immunotherapy of T cell malignancies

M. Piris, A. Akarca, T. Marafioti, 2017, Nature Medicine.

The promise of γδ T cells and the γδ T cell receptor for cancer immunotherapy

A. Sewell, D. Cole, M. Legut, 2015, Cellular and Molecular Immunology.

Genome-wide CRISPR-Cas9 Screening Reveals Ubiquitous T cell Cancer Targeting via the monomorphic MHC class I related protein MR1

M. Donia, I. Svane, A. Sewell, 2019, Nature Immunology.

Nonstimulatory peptide–MHC enhances human T-cell antigen-specific responses by amplifying proximal TCR signaling

Shvetha Sankaran, P. MacAry, A. Sewell, 2018, Nature Communications.

Vitamin C-driven epirubicin loading into liposomes

S. Barnert, M. Legut, A. Kozubek, 2013, International journal of nanomedicine.

Incorporation of Peptides Targeting EGFR and FGFR1 into the Adenoviral Fiber Knob Domain and Their Evaluation as Targeted Cancer Therapies

R. Stanton, H. Uusi-Kerttula, J. Chester, 2015, Human gene therapy.

A genome-scale screen for synthetic drivers of T cell proliferation

Neville E. Sanjana, Eleni P. Mimitou, Peter Smibert, 2022, Nature.

Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope

Andrew K. Sewell, John J. Miles, David K. Cole, 2017, Front. Immunol..

CRISPR-mediated TCR replacement generates superior anticancer transgenic T cells.

A. Sewell, G. Dolton, M. Legut, 2018, Blood.

Peptide–MHC Class I Tetramers Can Fail To Detect Relevant Functional T Cell Clonotypes and Underestimate Antigen-Reactive T Cell Populations

Andrew K. Sewell, Mark Peakman, Barbara Szomolay, 2018, The Journal of Immunology.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

Charles J. Vaske, Rohan N. Borkar, Brian D. Kelly, 2016, Journal of Immunotherapy for Cancer.

Title : CRISPR-mediated TCR replacement generates superior anticancer transgenic T-cells Running title : TCR replacement for cancer immunotherapy

A. Sewell, G. Dolton, M. Legut, 2017 .

The T cell antigen receptor: the Swiss army knife of the immune system

A. Sewell, D. Cole, M. Legut, 2015, Clinical and experimental immunology.

The promise of cd T cells and the cd T cell receptor for cancer immunotherapy

A. Sewell, D. Cole, M. Legut, 2015 .

Designer T-cells and T-cell receptors for customized cancer immunotherapies.

A. Sewell, M. Legut, Mateusz Legut, 2018, Current opinion in pharmacology.

Massively parallel Cas13 screens reveal principles for guide RNA design

Neville E. Sanjana, H. Wessels, M. Legut, 2020, Nature Biotechnology.

Massively parallel Cas13 screens reveal principles for guide RNA design

Neville E. Sanjana, H. Wessels, M. Legut, 2020, Nature Biotechnology.

Genome-wide CRISPR-Cas9 Screening Reveals Ubiquitous T cell Cancer Targeting via the monomorphic MHC class I related protein MR1

M. Donia, I. Svane, A. Sewell, 2019, Nature Immunology.

Partially differentiated polyfunctional T cells dominate the periphery after tumor-infiltrating lymphocytes therapy for cancer

M. Donia, I. Svane, S. Ott, 2016 .

Chemically modified guide RNAs enhance CRISPR-Cas13 knockdown in human cells.

Neville E. Sanjana, G. B. Robb, H. Wessels, 2021, Cell chemical biology.

Immunomagnetic cell sorting

Neville E. Sanjana, Mateusz Legut, M. Legut, 2019, Nature Biomedical Engineering.