Erwei Zuo

发表

Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos

L. Steinmetz, Yixue Li, Yidi Sun, 2019, Science.

A rationally engineered cytosine base editor retains high on-target activity while reducing both DNA and RNA off-target effects

Hui Yang, Changyang Zhou, Yixue Li, 2020, Nature Methods.

High-fidelity base editor with no detectable genome-wide off-target effects

Yixue Li, Yidi Sun, Erwei Zuo, 2020, bioRxiv.

Base editing generates substantial off-target single nucleotide variants

Lars M. Steinmetz, Hui Yang, L. Steinmetz, 2018, bioRxiv.

Chromosome-scale de novo assembly and phasing of a Chinese indigenous pig genome

Shawn Sullivan, Bradley J. Nelson, Ivan Liachko, 2019 .

Develop an efficient and specific AAV-based labeling system for Muller glia in mice

G. Geng, Erwei Zuo, Hui Yang, 2021, bioRxiv.

Single C-to-T substitution using engineered APOBEC3G-nCas9 base editors with minimum genome- and transcriptome-wide off-target effects

A. Kolomeisky, Isaac B. Hilton, Xue Gao, 2020, Science Advances.

Treatment of autosomal recessive hearing loss via in vivo CRISPR/Cas9-mediated optimized homology-directed repair in mice

Daqi Wang, Erwei Zuo, Hui Yang, 2022, Cell Research.

EpiCas-DL: Predicting sgRNA activity for CRISPR-mediated epigenome editing by deep learning

Yidi Sun, Erwei Zuo, Juan Meng, 2022, Computational and structural biotechnology journal.

CRISPR/Cas9-mediated targeted chromosome elimination

Hui Yang, Yu Wei, Jie Ping, 2017, Genome Biology.

Indiscriminate ssDNA cleavage activity of CRISPR-Cas12a induces no detectable off-target effects in mouse embryos

Yidi Sun, Erwei Zuo, Wenqin Ying, 2021, Protein & Cell.

CRISPR/Cas9-mediated targeted chromosome elimination

Yixue Li, J. Ping, Yidi Sun, 2017, Genome Biology.

One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs

Hui Yang, Yu Wei, Changyang Zhou, 2017, Cell Research.

Anti-silencing factor 1A is associated with genome stability maintenance of mouse preimplantation embryos†

Erwei Zuo, Yongjun Huang, D. Shi, 2020, Biology of Reproduction.

Disruption of splicing-regulatory elements using CRISPR/Cas9 to rescue spinal muscular atrophy in human iPSCs and mice

A. Krainer, Yidi Sun, Min-ting Lin, 2019, National science review.

Advances in detecting and reducing off-target effects generated by CRISPR-mediated genome editing.

Erwei Zuo, Hui Yang, Wan-Jin Chen, 2019, Journal of genetics and genomics = Yi chuan xue bao.

Identification of the Sex of Pre-implantation Mouse Embryos Using a Marked Y Chromosome and CRISPR/Cas9

Dongrong Chen, Ming Zhang, Erwei Zuo, 2019, Scientific Reports.

GOTI, a method to identify genome-wide off-target effects of genome editing in mouse embryos

L. Steinmetz, Yixue Li, Yidi Sun, 2020, Nature Protocols.

Base editing-mediated splicing correction therapy for spinal muscular atrophy

Ning Wang, Erwei Zuo, Wenqin Ying, 2020, Cell Research.

The advancements, challenges, and future implications of the CRISPR/Cas9 system in swine research.

Shuhong Zhao, Xinyun Li, Yuan Zhou, 2021, Journal of genetics and genomics = Yi chuan xue bao.

Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis

Hui Yang, Changyang Zhou, Yajing Liu, 2019, Nature.

The Potential of CRISPR/Cas9 Gene Editing as a Treatment Strategy for Inherited Diseases

Erwei Zuo, Yangqing Lu, S. Abdelnour, 2021, Frontiers in Cell and Developmental Biology.

Gene editing in a Myo6 semi-dominant mouse model rescues auditory function.

Geng-Lin Li, R. Chai, Huawei Li, 2021, Molecular therapy : the journal of the American Society of Gene Therapy.

Loss of function of CMPK2 causes mitochondria deficiency and brain calcification

Z. Xiong, Min-ting Lin, C. Liou, 2022, Cell Discovery.

Optimization of C-to-G base editors with sequence context preference predictable by machine learning methods

Yidi Sun, Erwei Zuo, Tanglong Yuan, 2021, Nature Communications.

Mitochondrial base editor DdCBE causes substantial DNA off-target editing in nuclear genome of embryos

Erwei Zuo, Hui Yang, Hu Feng, 2022, Cell discovery.

Human 8-cell embryos enable efficient induction of disease-preventive mutations without off-target effect by cytosine base editor

Yanzhi Du, Jiazhi Hu, Erwei Zuo, 2022, Protein & cell.

Human cleaving embryos enable efficient mitochondrial base-editing with DdCBE

Erwei Zuo, Hui Yang, Yu Wei, 2022, Cell Discovery.

Mini-dCas13X–mediated RNA editing restores dystrophin expression in a humanized mouse model of Duchenne muscular dystrophy

Erwei Zuo, Wenqin Ying, Hui Yang, 2022, The Journal of clinical investigation.

CRISPR-Cas9-mediated genome editing in one blastomere of two-cell embryos reveals a novel Tet3 function in regulating neocortical development

Guoliang Xu, Qi Yin, Guangdun Peng, 2017, Cell Research.

Base editing-mediated splicing correction therapy for spinal muscular atrophy

Ning Wang, Erwei Zuo, Wenqin Ying, 2020, Cell Research.

Discovery of deaminase functions by structure-based protein clustering

Kunli Qu, Peng Han, Yonglun Luo, 2023, Cell.

Treatment of autosomal dominant retinitis pigmentosa caused by RHO-P23H mutation with high-fidelity Cas13X in mice

Han Yang, Jihong Wu, Erwei Zuo, 2023, Molecular therapy. Nucleic acids.

Cytosine base editors induce off-target mutations and adverse phenotypic effects in transgenic mice

Yidi Sun, Erwei Zuo, Tanglong Yuan, 2023, Nature Communications.

Genome-wide CRISPR off-target prediction and optimization using RNA-DNA interaction fingerprints

Guohui Chuai, Erwei Zuo, Qi Liu, 2023, Nature communications.

Programmable C‐to‐U RNA editing using the human APOBEC3A deaminase

Yidi Sun, Xingxu Huang, Erwei Zuo, 2020, The EMBO journal.