N. Copeland

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Accelerated Amyloid Deposition in the Brains of Transgenic Mice Coexpressing Mutant Presenilin 1 and Amyloid Precursor Proteins

D. Borchelt, D. Price, N. Jenkins, 1997, Neuron.

Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase

Joanna L. Jankowsky, Nancy A. Jenkins, D. Borchelt, 2004 .

Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase.

D. Borchelt, S. Younkin, L. Younkin, 2004, Human molecular genetics.

Mga, a dual‐specificity transcription factor that interacts with Max and contains a T‐domain DNA‐binding motif

N. Jenkins, R. Eisenman, E. Steingrímsson, 1999, The EMBO journal.

Human α-synuclein-harboring familial Parkinson's disease-linked Ala-53 → Thr mutation causes neurodegenerative disease with α-synuclein aggregation in transgenic mice

Nancy A. Jenkins, Ted M. Dawson, D. Price, 2002, Proceedings of the National Academy of Sciences of the United States of America.

ALS-Linked SOD1 Mutant G85R Mediates Damage to Astrocytes and Promotes Rapidly Progressive Disease with SOD1-Containing Inclusions

D. Borchelt, D. Price, L. Bruijn, 1997, Neuron.

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice.

D. Price, N. Jenkins, T. Dawson, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Synphilin-1 attenuates neuronal degeneration in the A53T alpha-synuclein transgenic mouse model.

D. Borchelt, C. Ross, N. Jenkins, 2010, Human molecular genetics.

Synphilin-1 attenuates neuronal degeneration in the A53T alpha-synuclein transgenic mouse model.

D. Borchelt, C. Ross, N. Jenkins, 2010, Human molecular genetics.

Ring Finger Protein 125 Is an Anti-Proliferative Tumor Suppressor in Hepatocellular Carcinoma

N. Jenkins, T. Kodama, Michiko Kodama, 2022, Cancers.

Mammalian Homolog of Drosophila retinal degeneration B Rescues the Mutant Fly Phenotype

P. Campochiaro, D. Zack, N. Jenkins, 1997, The Journal of Neuroscience.

Axonal Transport of Mutant Superoxide Dismutase 1 and Focal Axonal Abnormalities in the Proximal Axons of Transgenic Mice

D. Borchelt, D. Price, P. Wong, 1998, Neurobiology of Disease.

Perspectives on the Mechanisms of Familial Amyotrophic Lateral Sclerosis Caused by Mutations in Superoxide Dismutase 1

D. Borchelt, D. Price, P. Wong, 1997 .

Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA

D. Borchelt, N. Jenkins, V. Gonzales, 2005, Neurobiology of Disease.

Hyperaccumulation of FAD-linked presenilin 1 variants in vivo

D. Borchelt, D. Price, A. Levey, 1997, Nature Medicine.

Accumulation of proteolytic fragments of mutant presenilin 1 and accelerated amyloid deposition are co-regulated in transgenic mice

D. Borchelt, N. Jenkins, S. Sisodia, 2002, Neurobiology of Aging.

The status of voltage-dependent calcium channels in alpha 1E knock-out mice.

C. Fletcher, N. Jenkins, L. Philipson, 2000, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Corrigendum: Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin (Human Molecular Genetics (1999) 8 (397-407))

D. Borchelt, D. Price, C. Ross, 1999 .

Insertional mutagenesis identiﬁes genes that promote the immortalization of primary bone marrow progenitor cells

N. Jenkins, N. Copeland, Yang Du, 2005 .

A Mutant ataxin-3 fragment results from processing at a site N-terminal to amino acid 190 in brain of Machado–Joseph disease-like transgenic mice

C. Ross, N. Jenkins, N. Copeland, 2007, Neurobiology of Disease.

Induction of apo . ptosis by _ the mouse Nedd 2 gene , which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 [-converting enzyme

N. Jenkins, Sharad Kumar, M. Kinoshita, 2007 .

The Status of Voltage-Dependent Calcium Channels in α1E Knock-Out Mice

C. Fletcher, N. Jenkins, L. Philipson, 2000, The Journal of Neuroscience.

Generalized lymphoproliferative disease in mice, caused by a point mutation in the fas ligand

N. Jenkins, S. Nagata, Masato Tanaka, 1994, Cell.

The Laminin (cid:97) Chains: Expression, Developmental Transitions, and Chromosomal Locations of (cid:97) 1-5, Identification of Heterotrimeric Laminins 8–11, and Cloning of a Novel (cid:97) 3 Isoform

J. Sanes, D. Gilbert, N. Jenkins, 1997 .

In Vivo and Targeted Inactivation in Embryonic Stem Cells

D. Gilbert, N. Jenkins, L. Muglia, 2022 .

Retroviral Integration at the Epi1 Locus Cooperates with Nf1 Gene Loss in the Progression to Acute Myeloid Leukemia

D. Largaespada, D. Gilbert, N. Jenkins, 2001 .

Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice

C. Fletcher, N. Jenkins, N. Copeland, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo

Allan I. Levey, Nancy A. Jenkins, Rong Wang, 1996, Neuron.

Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein

N. Jenkins, E. Steingrímsson, K. J. Moore, 1993, Cell.

Parkinson's Disease α-Synuclein Transgenic Mice Develop Neuronal Mitochondrial Degeneration and Cell Death

D. Price, N. Jenkins, L. Martin, 2006, The Journal of Neuroscience.

The Human Aquaporin-5 Gene

N. Copeland, D. Gilbert, N. Jenkins, 1996, The Journal of Biological Chemistry.

The Gene for a Variant Form of the Polyadenylation Protein CstF-64 Is on Chromosome 19 and Is Expressed in Pachytene Spermatocytes in Mice*

N. Copeland, D. Gilbert, N. Jenkins, 2001, The Journal of Biological Chemistry.

N. Jenkins, P. Gruss, A. Mansouri, 1997, Developmental dynamics : an official publication of the American Association of Anatomists.

APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1

D. Borchelt, N. Jenkins, V. Gonzales, 2004, Neurobiology of Aging.

Endoproteolysis of Presenilin 1 and Accumulation of Processed Derivatives In Vivo

D. Borchelt, D. Price, J. Hardy, 1996, Neuron.

Open access, freely available online PLoS MEDICINE Persistent Amyloidosis following Suppression of Ab Production in a Transgenic Model of Alzheimer Disease

H. Lester, D. Borchelt, A. Savonenko, 2022 .

Synaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific protease

C. Fletcher, N. Jenkins, Scott M Wilson, 2002, Nature Genetics.

Tumor suppressor gene identification using retroviral insertional mutagenesis in Blm‐deficient mice

Takeshi Suzuki, Keiko Akagi, N. Jenkins, 2006, The EMBO journal.

Expression Patterns of Two Murine Homologs ofDrosophila Single-MindedSuggest Possible Roles in Embryonic Patterning and in the Pathogenesis of Down Syndrome

J. Rubenstein, C. Fletcher, N. Jenkins, 1996, Molecular and Cellular Neuroscience.

Nkx3.1, a murine homolog of Drosophila bagpipe, regulates epithelial ductal branching and proliferation of the prostate and palatine glands

N. Copeland, N. Jenkins, I. Komuro, 2000, Developmental dynamics : an official publication of the American Association of Anatomists.

Differential expression of the seven‐pass transmembrane cadherin genes Celsr1‐3 and distribution of the Celsr2 protein during mouse development

Yasuyuki Shima, T. Uemura, D. Gilbert, 2002, Developmental dynamics : an official publication of the American Association of Anatomists.

The OMP–lacZ Transgene Mimics the Unusual Expression Pattern of OR-Z6, a New Odorant Receptor Gene on Mouse Chromosome 6: Implication for Locus-Dependent Gene Expression

D. Gilbert, N. Jenkins, N. Copeland, 2001, The Journal of Neuroscience.

Sox4 cooperates with PU.1 haploinsufficiency in murine myeloid leukemia.

N. Jenkins, C. Dunbar, N. Copeland, 2011, Blood.

Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq

Michael B. Mann, N. Navin, A. Rust, 2016, Nature Biotechnology.

Isolation of a NCK-associated Kinase, PRK2, an SH3-binding Protein and Potential Effector of Rho Protein Signaling*

A. Sparks, D. Gilbert, N. Jenkins, 1996, The Journal of Biological Chemistry.

Molecular Characterization of the MouseTem1/endosialin Gene Regulated by Cell Density in Vitro and Expressed in Normal Tissues in Vivo *

N. Jenkins, S. Pastoreková, R. Opavsky, 2001, The Journal of Biological Chemistry.

Copper-binding-site-null SOD1 causes ALS in transgenic mice: aggregates of non-native SOD1 delineate a common feature.

D. Borchelt, N. Jenkins, V. Gonzales, 2003, Human molecular genetics.

Fibrillar Inclusions and Motor Neuron Degeneration in Transgenic Mice Expressing Superoxide Dismutase 1 with a Disrupted Copper-Binding Site

D. Borchelt, N. Jenkins, V. Gonzales, 2002, Neurobiology of Disease.

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

D. Borchelt, D. Price, P. Wong, 1995, Neuron.

Expression and chromosomal localization of the Requiem gene

C. Larsson, B. Teh, N. Copeland, 1998, Mammalian Genome.

Identification of a Murine TEF-1-related Gene Expressed after Mitogenic Stimulation of Quiescent Fibroblasts and during Myogenic Differentiation*

N. Copeland, D. Gilbert, N. Jenkins, 1996, The Journal of Biological Chemistry.

Chromosomal Localization of the Myelin‐Associated Oligodendrocytic Basic Protein and Expression in the Genetically Linked Neurological Mouse Mutants Ducky and Tippy

M. Schwab, D. Gilbert, N. Jenkins, 1997, Journal of neurochemistry.

Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin.

D. Borchelt, D. Price, C. Ross, 1999, Human molecular genetics.

A Mouse Amidase Specific for N-terminal Asparagine

S. Arfin, N. Jenkins, A. Varshavsky, 1996, The Journal of Biological Chemistry.

Genetic Analysis of Voltage-Dependent Calcium Channels

C. Fletcher, N. Jenkins, N. Copeland, 1998, Journal of bioenergetics and biomembranes.

Highly restricted expression of Cre recombinase in cerebellar Purkinje cells

N. Jenkins, J. Tanner, Jian-Dong Huang, 2004, Genesis.

Distinct Behavioral and Neuropathological Abnormalities in Transgenic Mouse Models of HD and DRPLA

D. Borchelt, D. Price, C. Ross, 2001, Neurobiology of Disease.

Dystonia and cerebellar atrophy in Cacna1a null mice lacking P/Q calcium channel activity

C. Fletcher, N. Jenkins, D. Hosford, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Genetic mapping of the galanin-GMAP (Galn) gene to mouse Chromosome 19

N. Copeland, D. Gilbert, N. Jenkins, 1998, Mammalian Genome.

Nuclear-targeting of mutant huntingtin fragments produces Huntington's disease-like phenotypes in transgenic mice.

D. Borchelt, A. Savonenko, C. Ross, 2004, Human molecular genetics.

Nuclear Accumulation of Truncated Atrophin-1 Fragments in a Transgenic Mouse Model of DRPLA

D. Borchelt, D. Price, C. Ross, 1999, Neuron.

H. Eguchi, N. Jenkins, H. Suemizu, 2022, Hepatology.

cDNA cloning and chromosomal mapping of mouse fast skeletal muscle troponin T

N. Copeland, D. Gilbert, N. Jenkins, 1997, Mammalian Genome.

Genesis, a Winged Helix Transcriptional Repressor with Expression Restricted to Embryonic Stem Cells*

M. Klemsz, D. Largaespada, C. Fletcher, 1996, The Journal of Biological Chemistry.

Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death.

D. Price, N. Jenkins, L. Martin, 2006, The Journal of neuroscience : the official journal of the Society for Neuroscience.

A novel transgenic marker for migrating limb muscle precursors and for vascular smooth muscle cells

N. Copeland, D. Gilbert, N. Jenkins, 2001, Developmental dynamics : an official publication of the American Association of Anatomists.

Somatodendritic accumulation of misfolded SOD1-L126Z in motor neurons mediates degeneration: alphaB-crystallin modulates aggregation.

D. Borchelt, N. Jenkins, Hong Li, 2005, Human molecular genetics.

Progressive phenotype and nuclear accumulation of an amino-terminal cleavage fragment in a transgenic mouse model with inducible expression of full-length mutant huntingtin

D. Borchelt, C. Ross, Cameron Torcassi, 2006, Neurobiology of Disease.

Netrin-3, a Mouse Homolog of Human NTN2L, Is Highly Expressed in Sensory Ganglia and Shows Differential Binding to Netrin Receptors

D. Gilbert, N. Jenkins, M. Tessier-Lavigne, 1999, The Journal of Neuroscience.

Genomic Organization, Chromosomal Localization, Tissue Distribution, and Biophysical Characterization of a Novel MammalianShaker-related Voltage-gated Potassium Channel, Kv1.7*

H. Mohrenweiser, N. Jenkins, K. Chandy, 1998, The Journal of Biological Chemistry.

Parkinson'sDisease-SynucleinTransgenicMiceDevelop NeuronalMitochondrialDegenerationandCellDeath

Michael K. Lee, N. Copeland, 2006 .

Expression Patterns of Two Murine Homologs ofDrosophila Single-MindedSuggest Possible Roles in Embryonic Patterning and in the Pathogenesis of Down Syndrome Volume7,Number 1 (1996), pages 1–16:

J. Rubenstein, C. Fletcher, N. Jenkins, 1996, Molecular and Cellular Neuroscience.

A novel cytokine‐inducible gene CIS encodes an SH2‐containing protein that binds to tyrosine‐phosphorylated interleukin 3 and erythropoietin receptors.

N. Copeland, D. Gilbert, N. Jenkins, 1995, The EMBO journal.

Organization of the mouse microfibril-associated glycoprotein-2 (MAGP-2) gene

N. Copeland, D. Gilbert, N. Jenkins, 2000, Mammalian Genome.

Musashi1‐CreERT2: A new cre line for conditional mutagenesis in neural stem cells

N. Jenkins, L. Tessarollo, N. Copeland, 2013, Genesis.

An ancient, highly conserved family of cysteine-rich protein domains revealed by cloning type I and type II murine macrophage scavenger receptors.

M. Freeman, N. Copeland, N. Jenkins, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Angiopoietins 3 and 4: diverging gene counterparts in mice and humans.

N. Copeland, D. Gilbert, N. Jenkins, 1999, Proceedings of the National Academy of Sciences of the United States of America.

The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen.

N. Copeland, N. Jenkins, S. Nagata, 1992, Journal of immunology.

Molecular cloning, chromosomal localization, and bacterial expression of a murine macrophage metalloelastase.

T. Ley, N. Copeland, D. Gilbert, 1992, The Journal of biological chemistry.

A genetic linkage map of the mouse: current applications and future prospects.

E. Lander, J. Eppig, J. Nadeau, 1993, Science.

Characterization of murine CD70 by molecular cloning and mAb.

N. Copeland, D. Gilbert, N. Jenkins, 1998, International immunology.

bcl-w, a novel member of the bcl-2 family, promotes cell survival.

N. Copeland, N. Jenkins, G. Sutherland, 1996, Oncogene.

Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins

D. Baltimore, N. Copeland, N. Jenkins, 1991, Molecular and cellular biology.

An efficient recombination system for chromosome engineering in Escherichia coli.

D. Court, N. Copeland, N. Jenkins, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Meis1 preserves hematopoietic stem cells in mice by limiting oxidative stress.

N. Copeland, N. Jenkins, L. Tessarollo, 2012, Blood.

Mouse models of human disease. Part I: techniques and resources for genetic analysis in mice.

N. Copeland, N. Jenkins, M. Bedell, 1997, Genes & development.

TECK: a novel CC chemokine specifically expressed by thymic dendritic cells and potentially involved in T cell development.

N. Copeland, D. Gilbert, N. Jenkins, 1997, Immunity.

The IRS-2 gene on murine chromosome 8 encodes a unique signaling adapter for insulin and cytokine action.

N. Copeland, N. Jenkins, M. White, 1997, Molecular endocrinology.

Co-expression of multiple transgenes in mouse CNS: a comparison of strategies.

D. Borchelt, N. Copeland, N. Jenkins, 2001, Biomolecular engineering.

A mouse homolog of the Saccharomyces cerevisiae meiotic recombination DNA transesterase Spo11p.

S. Keeney, K. Manova, N. Copeland, 1999, Genomics.

A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA.

D. Court, N. Copeland, N. Jenkins, 2001, Genomics.

Molecular genetic analysis of the dilute-short ear (d-se) region of the mouse.

N. Copeland, N. Jenkins, N. Copeland, 1986, Genetics.

The leukemia inhibitory factor receptor (LIFR) gene is located within a cluster of cytokine receptor loci on mouse chromosome 15 and human chromosome 5p12-p13.

K. Huebner, N. Copeland, D. Gilbert, 1993, Genomics.

Structural comparison and chromosomal localization of the human and mouse IL-13 genes.

D. Largaespada, U. Francke, N. Copeland, 1993, Journal of immunology.

A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit.

N. Copeland, N. Jenkins, I. Lemischka, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development.

N. Copeland, N. Jenkins, P. Gruss, 1995, Development.

microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family.

James A. Vaught, Michael J. Hansen, N. Copeland, 1994, Genes & development.

The promise of comparative genomics in mammals.

S. O’Brien, W. Nash, W. Murphy, 1999, Science.

Mouse models of human disease. Part II: recent progress and future directions.

D. Largaespada, N. Copeland, N. Jenkins, 1997, Genes & development.

Pw1, a novel zinc finger gene implicated in the myogenic and neuronal lineages.

N. Jenkins, D. Sassoon, N. Copeland, 1996, Developmental biology.

Mad3 and Mad4: novel Max‐interacting transcriptional repressors that suppress c‐myc dependent transformation and are expressed during neural and epidermal differentiation.

N. Copeland, N. Jenkins, R. Eisenman, 1995, The EMBO journal.

Embryonic RNA expression patterns of the c‐kit receptor and its cognate ligand suggest multiple functional roles in mouse development.

N. Copeland, N. Jenkins, E. Keshet, 1991, The EMBO journal.

Comparative mapping of the human 22q11 chromosomal region and the orthologous region in mice reveals complex changes in gene organization.

R. Kucherlapati, B. Morrow, N. Copeland, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Chromosomal mapping of five highly conserved murine homologues of the Drosophila RING finger gene seven-in-absentia.

D. Bowtell, C. Fletcher, N. Copeland, 1997, Genomics.

Mapping of two genes encoding members of a distinct subfamily of MAX interacting proteins: MAD to human chromosome 2 and mouse chromosome 6, and MXI1 to human chromosome 10 and mouse chromosome 19.

R. Brent, C. Disteche, S. Edelhoff, 1994, Oncogene.

Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development.

J. Nathans, N. Copeland, D. Gilbert, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Combined histologic and molecular features reveal previously unappreciated subsets of lymphoma in AKXD recombinant inbred mice.

N. Copeland, N. Jenkins, J. Ward, 2001, Leukemia research.

Loss of alleles at loci on human chromosome 11 during genesis of Wilms' tumour

N. Copeland, N. Jenkins, W. Cavenee, 1984, Nature.

The bHLH-Zip transcription factor Tfeb is essential for placental vascularization.

N. Copeland, N. Jenkins, E. Steingrímsson, 1998, Development.

Structure of the mouse IL-10 gene and chromosomal localization of the mouse and human genes.

N. Copeland, N. Jenkins, C. Brannan, 1992, Journal of immunology.

Cloning and characterization of two vertebrate homologs of the Drosophila eyes absent gene.

N. Spinner, M. Bucan, N. Copeland, 1997, Genome research.

Structure‐function integrity of the adult hippocampus depends on the transcription factor Bcl11b/Ctip2

N. Copeland, N. Jenkins, J. Fischer, 2016, Genes, brain, and behavior.

Reversal of left-right asymmetry: a situs inversus mutation.

N. Copeland, N. Jenkins, P. Overbeek, 1993, Science.

Ru2 and Ru encode mouse orthologs of the genes mutated in human Hermansky-Pudlak syndrome types 5 and 6

B. Roe, R. Elliott, R. Spritz, 2003, Nature Genetics.

Molecular cloning, chromosomal location, and tissue-specific expression of the murine cathepsin G gene.

T. Ley, N. Copeland, D. Gilbert, 1993, Blood.

A mutation in Rab27a causes the vesicle transport defects observed in ashen mice.

N. Copeland, N. Jenkins, Scott M Wilson, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Molecular basis of mouse microphthalmia (mi) mutations helps explain their developmental and phenotypic consequences

A. Ferré-D’Amaré, S. Burley, N. Copeland, 1994, Nature Genetics.

Mouse MHC class I-like Fc receptor encoded outside the MHC.

N. Copeland, D. Gilbert, N. Jenkins, 1993, Journal of immunology.

Structure, chromosome mapping and expression of the murine Fgf-6 gene.

N. Copeland, N. Jenkins, M. Mattei, 1990, Oncogene.

A novel LPS-inducible C-type lectin is a transcriptional target of NF-IL6 in macrophages.

S. Akira, N. Copeland, D. Gilbert, 1999, Journal of immunology.

Evolution of the avian sex chromosomes from an ancestral pair of autosomes.

H. Ellegren, T. Woodage, N. Copeland, 1998, Proceedings of the National Academy of Sciences of the United States of America.

N. Copeland, N. Jenkins, L. Lau, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor beta.

N. Copeland, D. Gilbert, N. Jenkins, 1997, Molecular endocrinology.

Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues.

N. Copeland, N. Jenkins, A. Perkins, 1994, Genes & development.

CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome

J. Belmont, al. et, S. Edelhoff, 1993, Science.

A melanocyte-specific gene, Pmel 17, maps near the silver coat color locus on mouse chromosome 10 and is in a syntenic region on human chromosome 12.

D. Barton, B. Kwon, U. Francke, 1991, Proceedings of the National Academy of Sciences of the United States of America.

The rhombotin gene family encode related LIM-domain proteins whose differing expression suggests multiple roles in mouse development.

N. Copeland, N. Jenkins, T. Rabbitts, 1992, Journal of molecular biology.

Organization, distribution, and stability of endogenous ecotropic murine leukemia virus DNA sequences in chromosomes of Mus musculus

N. Copeland, N. Jenkins, B. Taylor, 1982, Journal of virology.

Role of myosin VI in the differentiation of cochlear hair cells.

K. Steel, N. Copeland, N. Jenkins, 1999, Developmental biology.

Molecular genetic dissection of mouse unconventional myosin-VA: tail region mutations.

N. Copeland, N. Jenkins, J. D. Huang, 1998, Genetics.

Molecular genetic characterization of six recessive viable alleles of the mouse agouti locus.

N. Copeland, N. Jenkins, L. Siracusa, 1995, Genetics.

TLR6: A novel member of an expanding toll-like receptor family.

S. Akira, N. Copeland, D. Gilbert, 1999, Gene.

Excitatory but not inhibitory synaptic transmission is reduced in lethargic (Cacnb4(lh)) and tottering (Cacna1atg) mouse thalami.

C. Fletcher, N. Copeland, N. Jenkins, 1999, Journal of neurophysiology.

The mouse and human genes encoding the recognition component of the N-end rule pathway.

N. Copeland, N. Jenkins, A. Varshavsky, 1998, Proceedings of the National Academy of Sciences of the United States of America.

A novel IL‐1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types.

K. Huebner, N. Jenkins, D. Benjamin, 1991, The EMBO journal.

Homeobox genes and connective tissue patterning.

V. Hartenstein, S. Zipursky, N. Copeland, 1995, Development.

A HECT domain ubiquitin ligase closely related to the mammalian protein WWP1 is essential for Caenorhabditis elegans embryogenesis.

Kirby D. Johnson, N. Copeland, N. Jenkins, 2000, Gene.

Multiple mouse chromosomal loci for dynein-based motility.

C. Echeverri, R. Vallee, N. Copeland, 1996, Genomics.

Steel-Dickie mutation encodes a c-kit ligand lacking transmembrane and cytoplasmic domains.

D. Williams, N. Copeland, N. Jenkins, 1991, Proceedings of the National Academy of Sciences of the United States of America.

trkC, a receptor for neurotrophin-3, is widely expressed in the developing nervous system and in non-neuronal tissues.

N. Copeland, D. Gilbert, N. Jenkins, 1993, Development.

PEBP2 alpha B/mouse AML1 consists of multiple isoforms that possess differential transactivation potentials

N. Copeland, D. Gilbert, N. Jenkins, 1994, Molecular and cellular biology.

Glucose transporter gene expression in early mouse embryos.

N. Copeland, D. Gilbert, N. Jenkins, 1991, Development.

The Ikaros gene encodes a family of lymphocyte-restricted zinc finger DNA binding proteins, highly conserved in human and mouse.

K Georgopoulos, N. Copeland, N. Jenkins, 1996, Journal of immunology.

Lymphotactin: a cytokine that represents a new class of chemokine.

D. Largaespada, N. Copeland, N. Jenkins, 1994, Science.

Identification of a novel Sry-related gene and its germ cell-specific expression.

J. Inazawa, N. Copeland, D. Gilbert, 1999, Nucleic acids research.

Interspersed repetitive element polymerase chain reaction product mapping using a mouse interspecific backcross.

H. Lehrach, R. Cox, N. Copeland, 1991, Genomics.

Chromosomal localization of mouse bullous pemphigoid antigens. BPAG1 and BPAG2: identification of a new region of homology between mouse and human chromosomes.

N. Copeland, D. Gilbert, N. Jenkins, 1993, Genomics.

Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development.

D. Lacey, Kenji Nakamura, M. Katsuki, 2001, Development.

Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins

N. Copeland, N. Jenkins, M. Cleary, 1997, Molecular and cellular biology.

Localization of Evi-2 to chromosome 11: linkage to other proto-oncogene and growth factor loci using interspecific backcross mice.

N. Copeland, N. Jenkins, B. Taylor, 1988, Oncogene research.

The mouse N-acetylgalactosamine-6-sulfate sulfatase (Galns) gene: cDNA isolation, genomic characterization, chromosomal assignment and analysis of the 5'-flanking region.

N. Copeland, D. Gilbert, N. Jenkins, 2000, Biochimica et biophysica acta.

Cloning and characterization of a novel class II phosphoinositide 3-kinase containing C2 domain.

N. Copeland, D. Gilbert, N. Jenkins, 1998, Biochemical and biophysical research communications.

Four novel members of the connexin family of gap junction proteins. Molecular cloning, expression, and chromosome mapping.

J. Haefliger, N. Copeland, D. Gilbert, 1992, The Journal of biological chemistry.

Comparative molecular genetic analysis of lymphomas from six inbred mouse strains

N. Copeland, N. Jenkins, N. Copeland, 1988, Journal of virology.

Chromosomal localization of three pulmonary surfactant protein genes in the mouse.

N. Copeland, N. Jenkins, J. Whitsett, 1992, Genomics.

Functional features of EVI1 and EVI1Δ324 isoforms of MECOM gene in genome-wide transcription regulation and oncogenicity

Chia-Lin Wei, G. Bourque, N. Copeland, 2016, Oncogene.

DNA rearrangements located over 100 kb 5' of the Steel (Sl)-coding region in Steel-panda and Steel-contrasted mice deregulate Sl expression and cause female sterility by disrupting ovarian follicle development.

N. Copeland, N. Jenkins, C. Brannan, 1995, Genes & development.

Novel mammalian kinase related to yeast and fly chromosome segregation regulators is exclusively expressed in the germline

J. M. Centanni, N. Copeland, D. Gilbert, 1999 .

A Mef2 gene that generates a muscle-specific isoform via alternative mRNA splicing

N. Copeland, N. Jenkins, J. Martín, 1994, Molecular and cellular biology.

Regional localization of three convertases, PC1 (Nec-1), PC2 (Nec-2), and furin (Fur), on mouse chromosomes.

N. Seidah, N. Copeland, D. Gilbert, 1992, Genomics.

Molecular cloning and expression of the type 1 and type 2 murine receptors for tumor necrosis factor

N. Copeland, N. Jenkins, C. Smith, 1991, Molecular and cellular biology.

Characterization of the cDNA and gene for mouse tumour necrosis factor alpha converting enzyme (TACE/ADAM17) and its location to mouse chromosome 12 and human chromosome 2p25.

N. Copeland, D. Gilbert, N. Jenkins, 1999, Cytokine.

Molecular cloning of a diverged homeobox gene that is rapidly down-regulated during the G0/G1 transition in vascular smooth muscle cells.

N. Copeland, N. Jenkins, K. Walsh, 1993, Molecular and cellular biology.

The Mouse APLP2 Gene

A. Mammen, D. Gilbert, N. Jenkins, 1995, Journal of Biological Chemistry.

NF-AT5: the NF-AT family of transcription factors expands in a new direction.

N. Copeland, D. Gilbert, N. Jenkins, 1999, Cold Spring Harbor symposia on quantitative biology.

Spontaneous germ line virus infection and retroviral insertional mutagenesis in eighteen transgenic Srev lines of mice

N. Copeland, D. Gilbert, N. Jenkins, 1989, Molecular and cellular biology.

Chromosomal localization of seven members of the murine TGF-beta superfamily suggests close linkage to several morphogenetic mutant loci.

M. Dickinson, M. Justice, R. Derynck, 1990, Genomics.

Genetic structure and chromosomal mapping of MyD88.

S. Naylor, N. Copeland, D. Gilbert, 1997, Genomics.

Molecular cloning of a novel type 1 cytokine receptor similar to the common gamma chain.

N. Copeland, D. Gilbert, N. Jenkins, 2000, Blood.

Interspecific backcross mice show sex-specific differences in allelic inheritance.

N. Copeland, N. Jenkins, W. Alvord, 1991, Genetics.

Structure, expression, and chromosome location of the gene for the beta subunit of brain-specific Ca2+/calmodulin-dependent protein kinase II identified by transgene integration in an embryonic lethal mouse mutant

N. Copeland, D. Gilbert, N. Jenkins, 1992, Molecular and cellular biology.

Hypervariable yellow (Ahvy), a new murine agouti mutation: Ahvy displays the largest variation in coat color phenotypes of all known agouti alleles.

N. Copeland, N. Jenkins, L. Siracusa, 1995, Journal of Heredity.

Genomic organization, alternative polyadenylation, and chromosomal localization of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex.

N. Jenkins, E. Steingrímsson, N. Copeland, 1994, Genomics.

Chromosomal assignment and genomic structure of Il15.

N. Copeland, D. Gilbert, N. Jenkins, 1995, Genomics.

Narp, a novel member of the pentraxin family, promotes neurite outgrowth and is dynamically regulated by neuronal activity

C. Barnes, P. Worley, D. Gilbert, 1996, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Sequence analysis, chromosomal location, and developmental expression of the mouse preproendothelin-1 gene.

N. Copeland, D. Gilbert, N. Jenkins, 1996, Genomics.

Localization of the murine homolog of the anaplastic lymphoma kinase (AlK) gene on mouse chromosome 17.

S. Shurtleff, N. Copeland, D. Gilbert, 1995, Cytogenetics and cell genetics.

The mouse neurological mutant flailer expresses a novel hybrid gene derived by exon shuffling between Gnb5 and Myo5a.

N. Copeland, N. Jenkins, M. Meisler, 2000, Human molecular genetics.

Molecular genetic dissection of mouse unconventional myosin-VA: head region mutations.

N. Copeland, N. Jenkins, J. D. Huang, 1998, Genetics.

Deletion map of the coloboma (Cm) locus on mouse chromosome 2.

N. Copeland, N. Jenkins, N. Copeland, 1994, Genomics.

Mild osteopetrosis in the microphthalmia-oak ridge mouse. A model for intermediate autosomal recessive osteopetrosis in humans.

N. Copeland, N. Jenkins, E. Steingrímsson, 1995, The American journal of pathology.

cDNA cloning, expression, subcellular localization, and chromosomal assignment of mammalian aurora homologues, aurora-related kinase (ARK) 1 and 2.

N. Copeland, D. Gilbert, N. Jenkins, 1998, Biochemical and biophysical research communications.

Genomic organization and chromosome location of the murine Rpl23 gene

K. Kratochwil, N. Copeland, D. Gilbert, 2000, Cytogenetic and Genome Research.

Identification of genes within the Krd deletion on mouse Chromosome 19

N. Copeland, D. Gilbert, N. Jenkins, 1999, Mammalian Genome.

Voltage-gated potassium channel genes are clustered in paralogous regions of the mouse genome.

N. Copeland, D. Gilbert, N. Jenkins, 1994, Genomics.

Cloning, analysis, and chromosomal localization of Notch-1, a mouse homolog of Drosophila Notch.

N. Copeland, N. Jenkins, P. Swiatek, 1993, Genomics.

The mouse CD69 gene. Structure, expression, and mapping to the NK gene complex.

S. Ziegler, N. Copeland, D. Gilbert, 1994, Journal of immunology.

Identification and chromosomal mapping of a receptor tyrosine kinase with a putative phospholipid binding sequence in its ectodomain.

N. Copeland, D. Gilbert, N. Jenkins, 1994, Oncogene.

Identification and applications of repetitive probes for gene mapping in the mouse.

N. Copeland, N. Jenkins, L. Siracusa, 1991, Genetics.

Localization of the human gene allowing infection by gibbon ape leukemia virus to human chromosome region 2q11-q14 and to the homologous region on mouse chromosome 2

R. Eddy, T. Shows, N. Copeland, 1991, Journal of virology.

Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme.

N. Copeland, N. Jenkins, S. Kumar, 1994, Genes & development.

Cloning, expression, and chromosomal location of SHH and IHH: two human homologues of the Drosophila segment polarity gene hedgehog.

N. Copeland, D. Gilbert, N. Jenkins, 1995, Genomics.

Cloning and characterization of a mouse brain calcitonin receptor complementary deoxyribonucleic acid and mapping of the calcitonin receptor gene.

S. Krane, N. Copeland, D. Gilbert, 1994, Endocrinology.

The interleukin-4 receptor gene (IL4R) maps to 16p11.2-16p12.1 in human and to the distal region of mouse chromosome 7.

N. Copeland, D. Gilbert, N. Jenkins, 1991, Genomics.

Identification of 10 murine homeobox genes.

N. Copeland, D. Gilbert, N. Jenkins, 1991, Proceedings of the National Academy of Sciences of the United States of America.

The mouse and human excitatory amino acid transporter gene (EAAT1) maps to mouse chromosome 15 and a region of syntenic homology on human chromosome 5.

S. Amara, D. Gilbert, N. Jenkins, 1994, Genomics.

Developmental regulation of ovarian-specific Mos expression.

N. Copeland, N. Jenkins, G. V. Vande Woude, 1988, Oncogene.

Localization of the 70-kDa peroxisomal membrane protein to human 1p21-p22 and mouse 3.

D. Valle, W. Kearns, N. Copeland, 1993, Genomics.

Isolation of two novel WNT genes, WNT14 and WNT15, one of which (WNT15) is closely linked to WNT3 on human chromosome 17q21.

A. Bowcock, N. Copeland, N. Jenkins, 1997, Genomics.

The cut-homeodomain transcriptional activator HNF-6 is coexpressed with its target gene HNF-3 beta in the developing murine liver and pancreas.

C. Fletcher, N. Copeland, N. Jenkins, 1997, Developmental biology.

Meis1 preserves hematopoietic stem cells in mice by limiting oxidative stress.

N. Jenkins, L. Tessarollo, H. Grimes, 2012, Blood.

Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo

D. Borchelt, D. Price, A. Levey, 1996, Neuron.

Cloning and structure of the human corticotrophin releasing factor-binding protein gene (CRHBP)

K. Lewis, N. Copeland, N. Jenkins, 1993, Genomics.

The murine Bin1 gene functions early in myogenesis and defines a new region of synteny between mouse chromosome 18 and human chromosome 2.

W. Wasserman, N. Copeland, N. Jenkins, 1999, Genomics.

Neurturin, a novel neurotrophic factor, is localized to mouse chromosome 17 and human chromosome 19p13.3.

N. Copeland, D. Gilbert, N. Jenkins, 1997, Genomics.

A vector for expressing foreign genes in the brains and hearts of transgenic mice.

D L Price, D. Borchelt, D. Price, 1996, Genetic analysis : biomolecular engineering.

Identification of podocalyxin-like protein 1 as a novel cell surface marker for hemangioblasts in the murine aorta-gonad-mesonephros region.

N. Copeland, N. Jenkins, A. Miyajima, 1999, Immunity.

Cell binding specificity of mouse R-cadherin and chromosomal mapping of the gene.

N. Copeland, D. Gilbert, N. Jenkins, 1993, Journal of cell science.

Molecular cloning, chromosomal location, and tissue-specific expression of the murine cathepsin G gene.

T. Ley, D. Gilbert, N. Jenkins, 1993, Blood.

Chromosomal localisation, inducibility, tissue-specific expression and strain differences in three murine peroxisome-proliferator-activated-receptor genes.

N. Copeland, D. Gilbert, N. Jenkins, 1995, European journal of biochemistry.

Structural analysis of the functional gene and pseudogene encoding the murine granulocyte colony-stimulating-factor receptor.

N. Copeland, N. Jenkins, S. Nagata, 1994, European journal of biochemistry.

A molecular genetic linkage map of mouse chromosome 18 reveals extensive linkage conservation with human chromosomes 5 and 18.

V. Chapman, M. Justice, K. Kinzler, 1992, Genomics.

cDNA cloning, expression, mutagenesis of C-terminal isoleucine, genomic structure, and chromosomal localizations of murine 12-lipoxygenases.

N. Copeland, N. Jenkins, C. Funk, 1994, The Journal of biological chemistry.

Itchy mice: the identification of a new pathway for the development of autoimmunity.

N. Copeland, N. Jenkins, N. Copeland, 2008, Current topics in microbiology and immunology.

Evi-1, a murine zinc finger proto-oncogene, encodes a sequence-specific DNA-binding protein

N. Copeland, N. Jenkins, A. Perkins, 1991, Molecular and cellular biology.