P. Schubiger

发表

Quality of Animal Experiments in Anti-Angiogenic Cancer Drug Development – A Systematic Review

G. Folkers, J. Wernery, M. I. Martić-Kehl, 2015, PloS one.

Assessment of hypoxia and perfusion in human brain tumors using PET with 18F-fluoromisonidazole and 15O-H2O.

S. Ametamey, U. Roelcke, P. Schubiger, 2004, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

In vitro and in vivo characterization of novel 18F-labeled bombesin analogues for targeting GRPR-positive tumors.

S. Ametamey, L. Dinkelborg, M. Honer, 2010, Bioconjugate chemistry.

Targeting superficial bladder cancer by the intravesical administration of copper-67-labeled anti-MUC1 mucin monoclonal antibody C595.

H. Denley, A. Perkins, M. Price, 2000, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Tumor Targeting of Mono-, Di-, and Tetravalent Anti-p185HER-2 Miniantibodies Multimerized by Self-associating Peptides*

A. Plückthun, U. Zangemeister‐Wittke, P. Schubiger, 2001, The Journal of Biological Chemistry.

an Inhibitor of Protein Kinase C Target for the Anticancer and Radiosensitizing Agent PKC 412 ,-Kinase / Akt Survival Pathway Is a ′ The Phosphatidylinositide 3 Updated

D. Fabbro, S. Rocha, B. Hemmings, 2001 .

The phosphatidylinositide 3'-kinase/Akt survival pathway is a target for the anticancer and radiosensitizing agent PKC412, an inhibitor of protein kinase C.

D. Fabbro, S. Rocha, B. Hemmings, 2001, Cancer research.

Automated no-carrier-added synthesis of [1-11C]-labeled D- and L-enantiomers of lactic acid.

P. Schubiger, G. Westera, K. Drandarov, 2006, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Efficient inhibition of intra-peritoneal tumor growth and dissemination of human ovarian carcinoma cells in nude mice by anti-L1-cell adhesion molecule monoclonal antibody treatment.

P. Altevogt, A. Krüger, M. Honer, 2006, Cancer research.

In vitro and in vivo evaluation of a 99mTc(I)-labeled bombesin analogue for imaging of gastrin releasing peptide receptor-positive tumors.

A. Beck‐Sickinger, P. Schubiger, P. Bläuenstein, 2002, Nuclear medicine and biology.

A 99mTc(I)-postlabeled high affinity bombesin analogue as a potential tumor imaging agent.

R. Schibli, P. Schubiger, D. Tourwé, 2002, Bioconjugate chemistry.

Comparison of copper-67- and iodine-125-labeled anti-CEA monoclonal antibody biodistribution in patients with colorectal tumors.

F. Buchegger, P. Schubiger, A. Delaloye, 1997, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Synthesis, radiolabeling, in vitro and in vivo evaluation of [18F]-FPECMO as a positron emission tomography radioligand for imaging the metabotropic glutamate receptor subtype 5.

S. Ametamey, M. Honer, P. Schubiger, 2009, Nuclear medicine and biology.

Synthesis and in Vivo studies of [C-11]N-methylepibatidine: comparison of the stereoisomers.

A. Buck, P. Schubiger, G. Westera, 1999, Nuclear medicine and biology.

In-Line Radiolabeling: A Novel Continuous-Flow System for Commercial-Scale Protein Labeling

M. Parseghian, P. Schubiger, R. Waibel, 2009, Journal of Nuclear Medicine.

Effects of antifolate drugs on the cellular uptake of radiofolates in vitro and in vivo.

R. Schibli, P. Schubiger, C. Müller, 2006, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Derivatization of glucose and 2-deoxyglucose for transition metal complexation: substitution reactions with organometallic 99mTc and Re precursors and fundamental NMR investigations.

R. Schibli, P. Schubiger, R. Alberto, 2001, Chemistry.

Organometallic 99mTc-aquaion labels peptide to an unprecedented high specific activity.

R. Schibli, L. Jeannin, P. Schubiger, 1999, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Peptides radiolabeled with Re-186/188 and Tc-99m as potential diagnostic and therapeutic agents

R. Schibli, P. Schubiger, E. García‐Garayoa, 2007 .

Stabilization of neurotensin analogues: effect on peptide catabolism, biodistribution and tumor binding.

P. Schubiger, D. Tourwé, A. Blanc, 2002, Nuclear medicine and biology.

Monoamine oxidase B single-photon emission tomography with [123I]Ro 43-0463: imaging in volunteers and patients with temporal lobe epilepsy

B. Weber, A. Buck, A. Siegel, 1998, European Journal of Nuclear Medicine.

[76Br]Bromodeoxyuridine, a potential tracer for the measurement of cell proliferation by positron emission tomography, in vitro and in vivo studies in mice.

J. Ryser, P. Schubiger, P. Bläuenstein, 1999, Nuclear medicine and biology.

Copper-67 Radioimmunotherapy and Growth Inhibition by Anti–L1-Cell Adhesion Molecule Monoclonal Antibodies in a Therapy Model of Ovarian Cancer Metastasis

P. Altevogt, S. Ametamey, M. Honer, 2007, Clinical Cancer Research.

Vehicles, chelators, and radionuclides: choosing the "building blocks" of an effective therapeutic radioimmunoconjugate.

P. Schubiger, R. Alberto, A. Smith, 1996, Bioconjugate chemistry.

Cellular processing of copper-67-labeled monoclonal antibody chCE7 by human neuroblastoma cells.

H. Amstutz, P. Schubiger, H. Mäcke, 1995, Cancer research.

In vivo Evaluation of 177Lu- and 67/64Cu-Labeled Recombinant Fragments of Antibody chCE7 for Radioimmunotherapy and PET Imaging of L1-CAM-Positive Tumors

S. Ametamey, M. Honer, P. Schubiger, 2005, Clinical Cancer Research.

In vitro and in vivo evaluation of new radiolabeled neurotensin(8-13) analogues with high affinity for NT1 receptors.

P. Schubiger, D. Tourwé, E. Garayoa, 2001, Nuclear medicine and biology.

Optimising the radioimmunotherapy of malignant disease: the broadening choice of carrier and effector moieties.

P. Schubiger, A. Smith, 1995, Pharmaceutica acta Helvetiae.

SYNTHESIS AND IN VITRO AND IN VIVO EVALUATION OF [11C]METHYL-BIII277CL FOR IMAGING THE PCP-BINDING SITE OF THE NMDA RECEPTOR BY PET

S. Ametamey, M. Honer, P. Schubiger, 2002, Journal of receptor and signal transduction research.

Silicon-based building blocks for one-step 18F-radiolabeling of peptides for PET imaging.

S. Ametamey, L. Dinkelborg, U. Klar, 2008, Angewandte Chemie.

Chemical and biological characterization of new Re(CO)3/[99mTc](CO)3 bombesin analogues.

A. Beck‐Sickinger, P. Schubiger, D. Tourwé, 2007, Nuclear medicine and biology.

Improving the tumor uptake of 99mTc-labeled neuropeptides using stabilized peptide analogues.

A. Beck‐Sickinger, P. Schubiger, D. Tourwé, 2004, Cancer Biotherapy and Radiopharmaceuticals.

Assessment of the binding properties of Granuloszint

P. Schubiger, P. Bläuenstein, P. Hasler, 2004, European Journal of Nuclear Medicine.

Faster analysis of radiopharmaceuticals using ultra performance liquid chromatography (UPLC) in combination with low volume radio flow cell.

S. Ametamey, P. Schubiger, P. Davi, 2009, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Tumor uptake and metabolism of copper-67-labeled monoclonal antibody chCE7 in nude mice bearing neuroblastoma xenografts.

H. Amstutz, P. Schubiger, H. Maecke, 1997, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Fluorine-18 click radiosynthesis and preclinical evaluation of a new 18F-labeled folic acid derivative.

S. Ametamey, M. Honer, R. Schibli, 2008, Bioconjugate chemistry.

Imaging of inflammatory and infectious lesions after injection of radioiodinated monoclonal anti-granulocytes antibodies.

F. Buchegger, P. Schubiger, J. Locher, 1986, Nuclear medicine communications.

Efficient synthesis of enantiomerically pure thioester precursors of [11c]McN-5652 from racemic McN-5652

F. Vollenweider, J. Steinbach, P. Brust, 1999 .

First organometallic inhibitors for human thymidine kinase: synthesis and in vitro evaluation of rhenium(I)- and technetium(I)-tricarbonyl complexes of thymidine

L. Scapozza, M. Birringer, R. Schibli, 2003 .

Internalization and degradation of monoclonal antibody chCE7 by human neuroblastoma cells

H. Amstutz, P. Schubiger, J. Morgenthaler, 1994, International journal of cancer.

Peptide linkers lead to modification of liver metabolism and improved tumor targeting of copper-67-labeled antibody fragments.

P. Schubiger, K. Zimmermann, I. Novak‐Hofer, 2001, Cancer biotherapy & radiopharmaceuticals.

Design, synthesis, and initial evaluation of a high affinity positron emission tomography probe for imaging matrix metalloproteinases 2 and 9.

S. Ametamey, L. Dinkelborg, S. Krämer, 2013, Journal of medicinal chemistry.

Preclinical evaluation of novel organometallic 99mTc-folate and 99mTc-pteroate radiotracers for folate receptor-positive tumour targeting

R. Schibli, P. Schubiger, C. Müller, 2006, European Journal of Nuclear Medicine and Molecular Imaging.

18F‐Radiolabeling of Aromatic Compounds Using Triarylsulfonium Salts

S. Ametamey, L. Dinkelborg, R. Schibli, 2012 .

In vitro and in vivo targeting of different folate receptor-positive cancer cell lines with a novel 99mTc-radiofolate tracer

R. Schibli, P. Schubiger, C. Müller, 2006, European Journal of Nuclear Medicine and Molecular Imaging.

Comparison of [18F]-Tracers in Various Experimental Tumor Models by PET Imaging and Identification of an Early Response Biomarker for the Novel Microtubule Stabilizer Patupilone

S. Ametamey, S. Ferretti, M. Honer, 2009, Molecular Imaging and Biology.

Potential of the "[M(CO)3]+" (M = Re, Tc) Moiety for the Labeling of Biomolecules

R. Schibli, P. Schubiger, R. Alberto, 1997 .

Differential inhibitory effect of L-lysine on renal accumulation of 67Cu-labelled F(abʼ)2 fragments in mice

P. Schubiger, R. Rutherford, R. Waibel, 1997 .

Evaluation of 177Lu-DOTA-labeled aglycosylated monoclonal anti-L1-CAM antibody chCE7: influence of the number of chelators on the in vitro and in vivo properties.

P. Schubiger, K. Zimmermann, J. Grünberg, 2006, Nuclear medicine and biology.

Targeting of renal carcinoma with 67/64Cu-labeled anti-L1-CAM antibody chCE7: selection of copper ligands and PET imaging.

S. Ametamey, M. Honer, P. Schubiger, 2003, Nuclear medicine and biology.

The soluble form of the cancer-associated L1 cell adhesion molecule is a pro-angiogenic factor.

E. Fischer, R. Schibli, P. Schubiger, 2009, The international journal of biochemistry & cell biology.

Non-invasive assessment of tumour cell proliferation with positron emission tomography and [76Br]bromodeoxyuridine.

G. V. von Schulthess, R. Dummer, H. Steinert, 1999, Melanoma research.

A comparison of 67Cu‐ and 131I‐labelled forms of monoclonal antibodies SEN7 and SWA20 directed against small‐cell lung cancer

R. Stahel, U. Zangemeister‐Wittke, P. Schubiger, 1994, International journal of cancer. Supplement = Journal international du cancer. Supplement.

A new precursor for the preparation of 6-[18F]Fluoro-L-m-tyrosine ([18F]FMT): efficient synthesis and comparison of radiolabeling.

S. Ametamey, Milen Blagoev, H. VanBrocklin, 2004, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

New [99mTc]bombesin analogues with improved biodistribution for targeting gastrin releasing-peptide receptor-positive tumors.

A. Beck‐Sickinger, P. Schubiger, D. Tourwé, 2007, The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of....

Double-stabilized neurotensin analogues as potential radiopharmaceuticals for NTR-positive tumors.

P. Schubiger, D. Tourwé, A. Blanc, 2006, Nuclear medicine and biology.

Radiofluorinated histamine H₃ receptor antagonist as a potential probe for in vivo PET imaging: radiosynthesis and pharmacological evaluation.

H. Stark, S. Ametamey, M. Honer, 2012, Bioorganic & medicinal chemistry.

Synthesis and in vitro/in vivo evaluation of novel 99mTc(CO)3-folates.

R. Schibli, P. Schubiger, C. Müller, 2006, Bioconjugate chemistry.

In vivo properties of N-(2-aminoethyl)-5-halogeno-2-pyridinecarboxamide 18F- and 123I-labelled reversible inhibitors of monoamine oxidase B.

A. Buck, S. Ametamey, P. Schubiger, 1998, Nuclear medicine and biology.

Evaluation of radioiodinated and radiocopper labeled monovalent fragments of monoclonal antibody chCE7 for targeting of neuroblastoma.

H. Amstutz, P. Schubiger, F. Carrel, 1997, Nuclear medicine and biology.

Biokinetics of a F(ab')3 iodine-131 labeled antigen binding construct (Mab 35) directed against CEA in patients with colorectal carcinoma.

R. Offord, F. Buchegger, P. Schubiger, 2001, Cancer biotherapy & radiopharmaceuticals.

Preparation of a trivalent antigen-binding construct using polyoxime chemistry: improved biodistribution and potential for therapeutic application.

K. Rose, R. Offord, P. Schubiger, 1996, Cancer research.

An improved method for the separation of 111Ag from irradiated natural palladium

P. Schubiger, R. Alberto, P. Bläuenstein, 1992 .

Synthesis, 18F-labeling, and in vitro and in vivo studies of bombesin peptides modified with silicon-based building blocks.

S. Ametamey, L. Dinkelborg, M. Friebe, 2008, Bioconjugate chemistry.

PET radiopharmaceuticals for neuroreceptor imaging

S. Ametamey, P. Schubiger, 2006 .

Synthesis and in vitro characterization of organometallic rhenium and technetium glucose complexes against Glut 1 and hexokinase.

L. Scapozza, R. Schibli, P. Schubiger, 2005, Bioconjugate chemistry.

Organometallic 99mTc-technetium(I)- and Re-rhenium(I)-folate derivatives for potential use in nuclear medicine

R. Schibli, P. Schubiger, C. Müller, 2004 .

Direct one-step 18F-labeling of peptides via nucleophilic aromatic substitution.

S. Ametamey, L. Dinkelborg, B. Koksch, 2009, Bioconjugate chemistry.

Differential inhibitory effect of L‐lysine on renal accumulation of 67Cu‐labelled F(ab′)2 fragments in mice

R. A. Rutherford, P. Schubiger, R. Rutherford, 1997, International Journal of Cancer.

[123I18F] N-(2-aminoethyl)-5-halogeno-2-pyridinecarbox-amides, site specific tracers for MAO-B mapping with SPET and PET☆

P. Schubiger, H. Beer, M. Häberli, 1995 .

Silver(I) Complexes of the Derivatized Crown Thioether Ligands 3,6,9,12,15,18-Hexathianonadecanol and 3,6,9,13,16,19-Hexathiaicosanol. Determination of Stability Constants and the Crystal Structures of [Ag(19-aneS6-OH)][CF(3)SO(3)] and [Ag(20-aneS6-OH)][BF(4)].

M. Neuburger, T. Kaden, P. Schubiger, 1996, Inorganic chemistry.

Isostructural folate conjugates radiolabeled with the matched pair 99mTc/188Re: a potential strategy for diagnosis and therapy of folate receptor-positive tumors.

R. Schibli, P. Schubiger, C. Müller, 2007, Nuclear medicine and biology.

Immunoscintigraphic localization of inflammatory lesions concept, radiolabelling and in vitro testing of a granulocyte specific antibody

F. Buchegger, P. Schubiger, J. Locher, 2007, European Journal of Nuclear Medicine.

Molecular imaging with PET.

Pius August Schubiger, Michael Honer, S. Ametamey, 2008, Chemical reviews.

Experience with the iodine-123 and technetium-99m labelled anti-granulocyte antibody MAb47: a comparison of labelling methods

P. Schubiger, G. Jánoki, J. Locher, 1995, European Journal of Nuclear Medicine.

Preclinical evaluation of copper-67 labelled anti-MUC1 mutin antibody C595 for therapeutic use in bladder cancer

A. Perkins, M. Price, P. Schubiger, 1997, European Journal of Nuclear Medicine.

A comparison of targetting of neuroblastoma with mIBG and anti L1-CAM antibody mAb chCE7: therapeutic efficacy in a neuroblastoma xenograft model and imaging of neuroblastoma patients

H. Amstutz, P. Schubiger, C. Hoefnagel, 2001, European Journal of Nuclear Medicine.

Preclinical evaluation of 67Cu-labeled intact and fragmented anti-colon carcinoma monoclonal antibody MAb35.

P. Schubiger, R. Alberto, H. Maecke, 1993, Cancer research.

Production and characterization of a mouse/human chimeric antibody directed against human neuroblastoma

H. Amstutz, K. Blaser, P. Schubiger, 1993, International journal of cancer.

Radioimmunolocalization of neuroblastoma xenografts with chimeric antibody chCE7.

H. Amstutz, K. Blaser, P. Schubiger, 1992, Journal of Nuclear Medicine.

Regulation of the cell surface expression of a nonspecific cross-reacting antigen variant during differentiation of HL-60 cells.

P. Schubiger, P. Bläuenstein, I. Novak‐Hofer, 1990, Cancer research.

Steps toward high specific activity labeling of biomolecules for therapeutic application: preparation of precursor [(188)Re(H(2)O)(3)(CO)(3)](+) and synthesis of tailor-made bifunctional ligand systems.

R. Schibli, P. Schubiger, R. Alberto, 2002, Bioconjugate chemistry.

Radiosynthesis of [11C]brofaromine, a potential tracer for imaging monoamine oxidase A.

K. Leenders, S. Ametamey, A. Antonini, 1996, Nuclear medicine and biology.

Radiometal labeling of antibodies and antibody fragments for imaging and therapy.

Benny K. C. Lo, A. Perkins, A. Murray, 2004, Methods in molecular biology.

Development of a simple and selective separation of 67Cu from irradiated zinc for use in antibody labelling: a comparison of methods.

P. Schubiger, P. Bläuenstein, K. Zimmermann, 1995, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Tumor Imaging in Patients with Advanced Tumors Using a New 99mTc-Radiolabeled Vitamin B12 Derivative

E. Fischer, I. Burger, R. Schibli, 2014, The Journal of Nuclear Medicine.

Comparison of two synthetic methods to obtain [18F] N-(2-aminoethyl)-5-fluoropyridine-2-carboxamide, a potential MAO-B imaging tracer for PET

S. Ametamey, P. Schubiger, H. Beer, 1995 .

123I-labeling and evaluation of Ro 43-0463, a SPET tracer for MAO-B imaging.

P. Schubiger, H. Beer, L. Frey, 1995, Nuclear medicine and biology.

Production and separation of ''non-standard'' PET nuclides at a large cyclotron facility: the experiences at the Paul Scherrer Institute in Switzerland.

R. Schibli, E. Schaub, P. Schubiger, 2008, The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of....

Synthesis of nor-β-CIT, β-CIT and trimethylstannyl-β-CT

C. Halldin, S. Ametamey, L. Farde, 1995 .

Neuronal nAChR stereoselectivity to non‐natural epibatidine derivatives

D. Bertrand, S. Bertrand, P. Schubiger, 1999, FEBS letters.

Synthesis and electrophysiological studies of a novel epibatidine analogue.

D. Bertrand, S. Bertrand, P. Schubiger, 1999, Journal of receptor and signal transduction research.

In vitro and in vivo testing of the dopamine D1 ligand [123I]SCH 23982 with respect to its potential application in SPET investigations.

W. Lichtensteiger, P. Schubiger, B. Weder, 1993, Nuclear medicine and biology.

Large scale preparation strategy for labelling of [123I]-SCH 23982, a dopamine D1 receptor binding agent.

P. Schubiger, H. Beer, P. Bläuenstein, 1992, International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes.

Catalytic enantioselective synthesis of 18F-fluorinated alpha-amino acids under phase-transfer conditions using (S)-NOBIN.

S. Ametamey, S. Vyskocil, P. Schubiger, 2004, Nuclear medicine and biology.

Measurement of tumor hypoxia in spontaneous canine sarcomas.

Barbara Kaser-Hotz, Carla Rohrer Bley, S. Ametamey, 2005, Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association.

Structural and (99)Tc NMR Investigations of Complexes with fac-[Tc(CO)(3)](+) Moieties and Macrocyclic Thioethers of Various Ring Sizes: Synthesis and X-ray Structure of the Complexes fac-[Tc(9-ane-S(3))(CO)(3)]Br, fac-[Tc(2)(tosylate)(2)(18-ane-S(6))(CO)(6)], and fac-[Tc(2)(20-ane-S(6)-OH)(CO)(6)][

R. Schibli, T. Kaden, P. Schubiger, 1998, Inorganic chemistry.

Central vs. peripheral Ag(i) coordination in NS3-open chain and cage ligands

T. Kaden, P. Schubiger, B. Spingler, 2002 .

Synthesis and reactivity of [NEt4]2[ReBr3(CO)3]. Formation and structural characterization of the clusters [NEt4][Re3(µ3-OH)(µ-OH)3(CO)9] and [NEt4][Re2(µ-OH)3(CO)6] by alkaline titration

V. Gramlich, P. Schubiger, R. Alberto, 1994 .

Synthesis of tricarbonyl rhenium and technetium complexes of a 5′-carboxamide 5-ethyl-2′-deoxyuridine for selective inhibition of herpes simplex virus thymidine kinase 1

R. Schibli, P. Schubiger, Dominique Desbouis, 2007 .

New derivatives of vitamin B12 show preferential targeting of tumors.

H. Moch, R. Schibli, P. Schubiger, 2008, Cancer research.

Reactions with the technetium and rhenium carbonyl complexes (NEt4)2[MX3(CO)3]. Synthesis and structure of [Tc(CN-But)3(CO)3](NO3) and (NEt4)[Tc2(μ-SCH2CH2OH)3(CO)6]

R. Schibli, T. Kaden, P. Schubiger, 1996 .

A simple single-step synthesis of [99Tc3H3(CO)12] from [99TcO4]– and its X-ray crystal structure. Application to the production of no-carrier added [188Re3H3(CO)12]

R. Schibli, T. Kaden, H. Berke, 1996 .

Versatile synthetic approach to new bifunctional chelating agents tailor made for labeling with the fac-[M(CO)(3)](+) core (M = Tc, (99m)Tc, Re): synthesis, in vitro, and in vivo behavior of the model complex [M(APPA)(CO)(3)] (APPA = [(5-amino-pentyl)-pyridin-2-yl-methyl-amino]-acetic acid).

R. Schibli, P. Schubiger, R. Waibel, 2003, Nuclear medicine and biology.

Steps towards [(C5Me5)TcO3]: Novel synthesis of [(C5Me5)Tc(CO)3] from [{Tc(μ3−OH)(CO)3}4] and oxidation of [(C5Me5)M(CO)3] (M = Tc, Re) with Br2

R. Schibli, T. Kaden, P. Schubiger, 1998 .

Syntheses of a series of S6 thioether cages and their coordination chemistry with Ag

T. Kaden, P. Schubiger, R. Alberto, 2007 .

Synthesis and Characterization of a C(6) Nucleoside Analogue for the in vivo Imaging of the Gene Expression of Herpes Simplex Virus Type‐1 Thymidine Kinase (HSV1 TK)

S. Ametamey, L. Scapozza, P. Schubiger, 2006, Chemistry & biodiversity.

Measurement of the extracellular space in brain tumors using 76Br-bromide and PET.

John Missimer, J. Missimer, S. Ametamey, 2003, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Ligand Selectivity for the Acetylcholine Binding Site of the Rat α4β2 and α3β4 Nicotinic Subtypes Investigated by Molecular Docking

L. Scapozza, W. Bisson, P. Schubiger, 2005 .

Synthesis and binding studies of epibatidine analogues as ligands for the nicotinic acetylcholine receptors.

W. Bisson, P. Schubiger, L. Mu, 2006, European journal of medicinal chemistry.

High thermal stability is essential for tumor targeting of antibody fragments: engineering of a humanized anti-epithelial glycoprotein-2 (epithelial cell adhesion molecule) single-chain Fv fragment.

A. Plückthun, R. Stahel, A. Honegger, 1999, Cancer research.

11C-radiolabeling of hallucinogenic psilocin, a potential radioligand for studying the role of serotonin receptors in psychotic symptom formation

F. Vollenweider, S. Ametamey, P. Schubiger, 1998 .

Synthesis, in vitro and in silico assessment of organometallic Rhenium(I) and Technetium(I) thymidine complexes

L. Scapozza, V. Spiwok, R. Schibli, 2007 .

PET imaging of dopamine transporters in the human brain using [11C]-β-CPPIT, a cocaine derivative lacking the 2β-ester function

F. Vollenweider, A. Buck, S. Kneifel, 2002 .

Immunoscintigraphic localization of inflammatory lesions: Clinical experience

P. Schubiger, J. Locher, P. Bläuenstein, 2007, European Journal of Nuclear Medicine.

Chemical modification of epibatidine causes a switch from agonist to antagonist and modifies its selectivity for neuronal nicotinic acetylcholine receptors.

D. Bertrand, S. Bertrand, P. Schubiger, 2000, Chemistry & biology.

Comparison of N-[(11)C]methyl-norchloroepibatidine and N-[(11)C]methyl-2-(2-pyridyl)-7-azabicyclo[2.2.1]heptane with N-[(11)C]methyl-epibatidine in small animal PET studies.

P. Schubiger, G. Westera, J. Patt, 2000, Nuclear medicine and biology.

Organofluorosilanes as model compounds for 18F-labeled silicon-based PET tracers and their hydrolytic stability: experimental data and theoretical calculations (PET = positron emission tomography).

S. Ametamey, U. Klar, M. Reiher, 2009, Chemistry.

From Mice to Men: Translation from Bench to Bedside

M. I. Martić-Kehl, P. Schubiger, P. A. Schubiger, 2016 .

Help-Seeking in People with Exceptional Experiences: Results from a General Population Sample

P. Brugger, W. Kawohl, H. Haker, 2014, Front. Public Health.

Progress in Radiopharmacy

P. Schubiger, G. Westera, 1992, Developments in Nuclear Medicine.

Regional quantitative noninvasive assessment of cerebral perfusion and function with N-isopropyl-[123I]p-iodoamphetamine.

G. V. von Schulthess, P. Schubiger, E. Ketz, 1985, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

PET Chemistry: The Driving Force in Molecular Imaging

David J. Yang, P. A. Schubiger, Matthias Friebe, 2007, Journal of Nuclear Medicine.

Synthesis, radiolabelling and biological characterization of (D)-7-iodo-N-(1-phosphonoethyl)-5-aminomethylquinoxaline-2,3-dione, a glycine-binding site antagonist of NMDA receptors.

S. Ametamey, Y. Auberson, P. Schubiger, 2000, Bioorganic & medicinal chemistry letters.

Radioligands for the PET imaging of metabotropic glutamate receptor subtype 5 (mGluR5).

S. Ametamey, P. Schubiger, L. Mu, 2010, Current topics in medicinal chemistry.

Radiolabeling and in vitro and in vivo evaluation of [18F]-FE-DABP688 as a PET radioligand for the metabotropic glutamate receptor subtype 5.

S. Ametamey, M. Honer, P. Schubiger, 2007, Nuclear medicine and biology.

A comparison of 67CU production by proton (67 TO 12 MEV) induced reactions on NATZN and on enriched 68ZN/70ZN

P. Schubiger, K. Zimmermann, I. Novak‐Hofer, 2001 .

Comprar PET Chemistry · The Driving Force in Molecular Imaging | Schubiger, P.A. | 9783540326236 | Springer

P. A. Schubiger, Matthias Friebe, M. Friebe, 2007 .

PET studies of 18F-memantine in healthy volunteers.

A. Buck, S. Kneifel, S. Ametamey, 2002, Nuclear medicine and biology.

Can animal data predict human outcome? Problems and pitfalls of translational animal research

Roger Schibli, R. Schibli, M. I. Martić-Kehl, 2012, European Journal of Nuclear Medicine and Molecular Imaging.

NanoPET imaging of [18F]fluoromisonidazole uptake in experimental mouse tumours

Simon M. Ametamey, Michael Honer, M. Wyss, 2006, European Journal of Nuclear Medicine and Molecular Imaging.

Synthesis and in vivo studies of the stereoisomers of N-[11C]methyl-homoepibatidine.

A. Buck, M. Arras, P. Schubiger, 2001, Nuclear medicine and biology.

Conjugates of vitamin B12 with Nε-functionalized histidine for labeling with [99mTc(OH2)3(CO)3]+: synthesis and biodistribution studies in tumor bearing mice

P. Schubiger, R. Alberto, R. Waibel, 2004 .

Homology modeling and dynamics of the extracellular domain of rat and human neuronal nicotinic acetylcholine receptor subtypes α4β2 and α7

L. Scapozza, W. Bisson, P. Schubiger, 2008, Journal of molecular modeling.

Electrophysiological study, biodistribution in mice, and preliminary PET evaluation in a rhesus monkey of 1-amino-3-[18F]fluoromethyl-5-methyl-adamantane (18F-MEM): a potential radioligand for mapping the NMDA-receptor complex.

C. Parsons, K. Leenders, S. Ametamey, 1998, Nuclear medicine and biology.

Functional imaging of physiological processes by positron emission tomography.

Gerrit Westera, P. Schubiger, G. Westera, 2003, News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society.

Radiosynthesis and preclinical evaluation of 11C-ABP688 as a probe for imaging the metabotropic glutamate receptor subtype 5.

Yves P Auberson, Alfred Buck, Michael Honer, 2006, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Chemical modifications of 99mTc tricarbonyl labeled single chain antibody fragments for improved in vivo behavior in tumor targeting

P. Schubiger, R. Waibel, K. Chester, 2001 .

18F-Labeled Bombesin Analog for Specific and Effective Targeting of Prostate Tumors Expressing Gastrin-Releasing Peptide Receptors

S. Ametamey, L. Dinkelborg, M. Honer, 2011, The Journal of Nuclear Medicine.

Impact of inherent variability and experimental parameters on the reliability of small animal PET data

Pius August Schubiger, Michael Honer, Malte F. Alf, 2012, EJNMMI Research.

[123I/125I]-Ro 43-0463, a site specific tracer for MAO-B mapping with autoradiography as well as with SPET.

P. Schubiger, H. Beer, N. Rémy, 1995, Journal of receptor and signal transduction research.

Comparison of [18F]FDOPA, [18F]FMT and [18F]FECNT for imaging dopaminergic neurotransmission in mice.

Milen Blagoev, Michael Honer, Bastian Hengerer, 2006, Nuclear medicine and biology.

Positron emission tomography in drug evaluation: influence of three different catechol-O-methyltransferase inhibitors on metabolism of [NCA] 6-[18F]fluoro-L-dopa in rhesus monkey.

A. Antonini, P. Schubiger, P. Vontobel, 1995, Nuclear medicine and biology.

4-[18F]fluoroglutamic acid (BAY 85-8050), a new amino acid radiotracer for PET imaging of tumors: synthesis and in vitro characterization.

S. Ametamey, L. Dinkelborg, M. Friebe, 2011, Journal of medicinal chemistry.

Antibodies directed against L1-CAM synergize with Genistein in inhibiting growth and survival pathways in SKOV3ip human ovarian cancer cells.

P. Altevogt, P. Schubiger, Susan Cohrs, 2008, Cancer letters.

Hepatocyte Growth Factor-induced Ectodomain Shedding of Cell Adhesion Molecule L1

P. Schubiger, J. Grünberg, I. Novak‐Hofer, 2004, Journal of Biological Chemistry.

Reinvestigation of a physiological eluate of the 52Fe/52mMn generator.

P. Schubiger, P. Bläuenstein, R. Pellikka, 1997, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Synthesis and preliminary in vitro evaluation of a new memantine derivative 1‐amino‐3‐[18F]fluoromethyl‐5‐methyl‐adamantane: A potential ligand for mapping the N‐methyl‐D‐aspartate receptor complex

S. Ametamey, S. Samnick, P. Schubiger, 1997 .

Synthesis, in vitro and in vivo evaluation of [11C]‐methyl‐BIII277CL as a pet radioligand for imaging the pcp‐binding site of the NMDA‐receptor complex

S. Ametamey, M. Honer, P. Schubiger, 2001 .

Immunoscintigraphic localization of inflammatory lesions: Pharmacokinetics and estimated absorbed radiation dose in man

P. Schubiger, J. Locher, P. Hasler, 2007, European Journal of Nuclear Medicine.

In Vitro and in Vivo Comparison of Some Properties of Antigranulocyte Antibodies

P. Schubiger, J. Locher, P. Bläuenstein, 1994 .

Tc(I), Re(I), Ag(I)-Complexes with the Goal of Radiolabelling Biomolecules for Nuclear Medicine Applications

P. Schubiger, R. Alberto, 1999 .

Assessment of serotonin release capacity in the human brain using dexfenfluramine challenge and [18F]altanserin positron emission tomography

Valerie Treyer, Alfred Buck, Cyrill Burger, 2012, NeuroImage.

A triglycine linker improves tumor uptake and biodistributions of 67-Cu-labeled anti-neuroblastoma MAb chCE7 F(ab')2 fragments.

P. Schubiger, K Zimmermann, S Gianollini, 1999, Nuclear medicine and biology.

Syntheses and pharmacological characterization of novel thiazole derivatives as potential mGluR5 PET ligands.

S. Ametamey, M. Honer, S. Krämer, 2010, Bioorganic & Medicinal Chemistry.

Anti-Angiogenic/Vascular Effects of the mTOR Inhibitor Everolimus Are Not Detectable by FDG/FLT-PET.

H. Lane, S. Ametamey, T. O'reilly, 2010, Translational oncology.

[18F]Fluorosilicon- and [18F]Fluoroboron-based Biomolecules for PET Imaging

S. Ametamey, P. Schubiger, L. Mu, 2010 .

Fluorine-18 radiolabelling, biodistribution studies and preliminary PET evaluation of a new memantine derivative for imaging the NMDA receptor.

C. Parsons, K. Leenders, S. Ametamey, 1999, Journal of receptor and signal transduction research.

Application of the organometallic technetium and rhenium tricarbonyl complex on neuropeptide labelling

P. Schubiger, D. Tourwé, A. Blanc, 2001 .

Structural investigations of re‐tricarbonyl labeled neurotensin analogues using 1D and 2D “magic angle spinning” NMR techniques

R. Schibli, P. Schubiger, D. Tourwé, 2001 .

Functionalization of glucose for the labeling with 99mTc‐tricarbonyl

L. Scapozza, R. Schibli, P. Schubiger, 2001 .

Copper-67 labeled mAb chCE7 as a potential therapeutic agent for neuroblastoma: improved biodistributions of copper-67-chCE7 F(ab’)2

H. Amstutz, P. Schubiger, H. Maecke, 1997 .

[123I/18F] N-(2-aminoethyl)-5-halogeno-2-pyridinecarbox-amides, site specific tracers for MAO-B mapping with SPECT and PET.

P. Schubiger, H. Beer, M. Häberli, 1995, Nuclear Medicine and Biology.

Catabolism of neurotensins. Implications for the design of radiolabeling strategies of peptides.

R. Schibli, P. Schubiger, R. Alberto, 1999, The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology.

In vitro and in vivo evaluation of [18F]-FDEGPECO as a PET tracer for imaging the metabotropic glutamate receptor subtype 5 (mGluR5)

Simon M. Ametamey, Linjing Mu, Stefanie D. Krämer, 2011, NeuroImage.

The Metamorphosis of Radionuclide Production and Development at Paul Scherrer Institute.

R. Schibli, P. Grundler, R. Eichler, 2020, Chimia.

S. Ametamey, S. Samnick, P. Schubiger, 1997 .

Tumor Imaging in Patients with Advanced Tumors Using a New 99mTc-Radiolabeled Vitamin B12 Derivative

E. Fischer, I. Burger, R. Schibli, 2014, The Journal of Nuclear Medicine.

Structure-activity relationships of fluorinated (E)-3-((6-methylpyridin-2-yl)ethynyl)cyclohex-2-enone-O-methyloxime (ABP688) derivatives and the discovery of a high affinity analogue as a potential candidate for imaging metabotropic glutamate recepors subtype 5 (mGluR5) with positron emission tomogr

S. Ametamey, M. Honer, P. Schubiger, 2010, Journal of medicinal chemistry.

Synthesis, radiolabeling, in vitro and in vivo evaluation of [18F]-FPECMO as a positron emission tomography radioligand for imaging the metabotropic glutamate receptor subtype 5.

S. Ametamey, M. Honer, P. Schubiger, 2009, Nuclear medicine and biology.

Versatile routes to C-2- and C-6-functionalized glucose derivatives of iminodiacetic acid.

R. Schibli, P. Schubiger, C. Dumas, 2003, The Journal of organic chemistry.

Minimally invasive biomarkers for therapy monitoring.

H. Lane, C. Schnell, J. Wood, 2007, Ernst Schering Foundation symposium proceedings.

Radiolabelling and in vivo evaluation of 11C–MPEP as a pet radioligand for the imaging of the metabotropic glutamate receptor 5 (MGLUR5)

Simon M. Ametamey, M. Kokic, Pius August Schubiger, 2001 .