D. Sévin

发表

Genomewide landscape of gene-metabolome associations in Escherichia coli.

U. Sauer, Nicola Zamboni, M. Zampieri, 2017, Molecular systems biology.

Biological insights through nontargeted metabolomics.

U. Sauer, Nicola Zamboni, D. Sévin, 2015, Current opinion in biotechnology.

Oncogenic memory underlying minimal residual disease in breast cancer

D. Machado, K. Patil, A. Alladin, 2020, bioRxiv.

An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation

Emma L. Koppe, L. O’Neill, D. Sévin, 2018, The Journal of Biological Chemistry.

Identifying drug targets in tissues and whole blood with thermal-shift profiling

Douglas W. Thomson, W. Huber, Christina Rau, 2020, Nature Biotechnology.

Exploring the adaptability and robustness of the central carbon metabolism of Mycoplasma pneumoniae

Niels A. Zondervan, V. M. D. Martins dos Santos, M. Suárez-Diez, 2022, bioRxiv.

Mouse organoids as an in vitro tool to study the in vivo intestinal response to cytotoxicants

B. Herpers, D. Sévin, D. Pritchard, 2022, Archives of Toxicology.

Proteome thermal stability reflects organ physiology and identifies drug-target engagement in vivo

Douglas W. Thomson, W. Huber, Christina Rau, 2018 .

Complementary NAD+ replacement strategies fail to functionally protect dystrophin-deficient muscle

David Frederick, Andrea Nuzzo, D. Sévin, 2020, Skeletal muscle.

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

Edward T Chouchani, John Szpyt, Mark P. Jedrychowski, 2018, Nature.

Consistency across multi-omics layers in a drug-perturbed gut microbial community

Thomas S. B. Schmidt, Philipp E. Geyer, P. Bork, 2023, bioRxiv.

The bZIP transcription factors HY5 and HYH are positive regulators of the main nitrate reductase gene in Arabidopsis leaves, NIA2, but negative regulators of the nitrate uptake gene NRT1.1.

C. Lillo, D. Sévin, E. M. Jonassen, 2009, Journal of plant physiology.

Bioaccumulation of therapeutic drugs by human gut bacteria

Ana Rita Brochado, P. Bork, M. Savitski, 2021, Nature.

New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids

J. Kleinjans, J. Saez-Rodriguez, Seung-Wook Chung, 2021, Archives of Toxicology.

Global Metabolic Responses to Salt Stress in Fifteen Species

U. Sauer, D. Sévin, Andreas Kuehne, 2016, PloS one.

Nontargeted in vitro metabolomics for high-throughput identification of novel enzymes in Escherichia coli

U. Sauer, Nicola Zamboni, Tobias Fuhrer, 2016, Nature Methods.

Inflating bacterial cells by increased protein synthesis

T. Hwa, M. Basan, Xiongfeng Dai, 2015, Molecular systems biology.

Metabolic memory underlying minimal residual disease in breast cancer

D. Machado, K. Patil, B. Brügger, 2021, Molecular systems biology.

Nontargeted Metabolomics Approaches for Enzyme Discovery and High-Resolution Metabolome Phenotyping

D. Sévin, 2016 .

Ubiquinone accumulation improves osmotic-stress tolerance in Escherichia coli.

U. Sauer, D. Sévin, 2014, Nature chemical biology.

Yeast Creates a Niche for Symbiotic Lactic Acid Bacteria through Nitrogen Overflow

Kiran Raosaheb Patil, Uwe Sauer, Markus Ralser, 2017, Cell systems.

Exometabolome profiling reveals activation of the carnitine buffering pathway in fed‐batch cultures of CHO cells co‐fed with glucose and lactic acid

D. Sévin, J. Aon, Pramthesh Patel, 2021, Biotechnology progress.

Identifying drug targets in tissues and whole blood with thermal-shift profiling

Douglas W. Thomson, W. Huber, M. Bantscheff, 2020, Nature Biotechnology.

Effect of topical applications of sunflower seed oil on systemic fatty acid levels in under-two children under rehabilitation for severe acute malnutrition in Bangladesh: a randomized controlled trial

G. Darmstadt, T. Ahmed, M. I. Hossain, 2021, Nutrition Journal.

The Neurometabolic Fingerprint of Excessive Alcohol Drinking

U. Sauer, W. Sommer, D. Sévin, 2015, Neuropsychopharmacology.

Life span extension by targeting a link between metabolism and histone acetylation in Drosophila

U. Sauer, T. Schauer, T. Straub, 2016, EMBO reports.

Characterization of the small flavin-binding dodecin in the roseoflavin producer Streptomyces davawensis.

J. Kalinowski, M. Grininger, M. Mack, 2018, Microbiology.

A dual control mechanism synchronizes riboflavin and sulphur metabolism in Bacillus subtilis

U. Sauer, B. Suess, D. Pedrolli, 2015, Proceedings of the National Academy of Sciences.

An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in ex vivo human precision-cut lung slices

R. Pepperkok, G. Bergamini, T. Muley, 2020, European Respiratory Journal.

Multiomic and quantitative label-free microscopy-based analysis of ex vivo culture and TGFbeta1 stimulation of human precision-cut lung slices

R. Pepperkok, G. Bergamini, T. Muley, 2019, bioRxiv.

Metabolic network segmentation: A probabilistic graphical modeling approach to identify the sites and sequential order of metabolic regulation from non-targeted metabolomics data

Manfred Claassen, Nicola Zamboni, Andreas Kühne, 2017, PLoS Comput. Biol..

Integrating metabolome dynamics and process data to guide cell line selection in biopharmaceutical process development.

M. Barolo, F. Bezzo, G. Finka, 2022, Metabolic engineering.

Consistency across multi‐omics layers in a drug‐perturbed gut microbial community

Philipp E. Geyer, P. Bork, R. Hercog, 2023, Molecular systems biology.

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

John Szpyt, Mark P. Jedrychowski, R. Fischer, 2018, Nature.

Inflating bacterial cells by increased protein synthesis

T. Hwa, M. Basan, Xiongfeng Dai, 2015, Molecular systems biology.

Genomewide landscape of gene–metabolome associations in Escherichia coli

U. Sauer, Nicola Zamboni, M. Zampieri, 2017, Molecular systems biology.

Molecular Systems Biology Peer Review Process File Inflating Bacterial Cells by Increased Protein Synthesis Transaction Report

T. Hwa, M. Basan, Xiongfeng Dai, 2022 .