Kenji Takahashi

发表

Three distinct-type glutathione S-transferases from Escherichia coli important for defense against oxidative stress.

T. Kanai, Kenji Takahashi, H. Inoue, 2006, Journal of biochemistry.

Novel peptide-based pepsin inhibitors containing an epoxide group

Hisashi Ito, Y. Morita, Kenji Takahashi, 2008 .

Effects of Cys10 mutation to Ala in glutathione transferase from Escherichia coli

M. Nishida, Kenji Takahashi, H. Inoue, 2000 .

Structural and enzymatic characterization of physarolisin (formerly physaropepsin) proves that it is a unique serine-carboxyl proteinase.

Masaki Kojima, M. Kojima, Kenji Takahashi, 2003, Biochemical and biophysical research communications.

The P1 and P1′ Residue Specificities of Physarolisin I, a Serine-Carboxyl Peptidase from the True Slime Mold Physarum polycephalum

Kenji Takahashi, K. Kubota, W. Nishii, 2009, Bioscience, biotechnology, and biochemistry.

Comparative studies on the acid proteinase activities in the digestive fluids of Nepenthes, Cephalotus, Dionaea, and Drosera

Koji Matsumoto, Kenji Takahashi, K. Kubota, 2009, Carnivorous Plant Newsletter.

Determination of the cleavage sites in SulA, a cell division inhibitor, by the ATP‐dependent HslVU protease from Escherichia coli

Kenji Takahashi, W. Nishii, 2003, FEBS letters.

Enzymic and structural characterization of nepenthesin, a unique member of a novel subfamily of aspartic proteinases.

A. Iwamatsu, Koji Matsumoto, M. Kojima, 2004, The Biochemical journal.

Aspartic Proteinases

R. Perlmutter, D. Poole, O. Mathieu-Costello, 1995, Advances in Experimental Medicine and Biology.

[10] Proteinase A from Aspergillus niger

Kenji Takahashi, 1995 .

The Significance of Low Serum Pepsinogen Levels to Detect Stomach Cancer Associated with Extensive Chronic Gastritis in Japanese Subjects

Kenji Takahashi, M. Matsushima, M. Ichinose, 1989, Japanese journal of cancer research : Gann.

A Cysteine Endopeptidase (“Dionain”) Is Involved in the Digestive Fluid of Dionaea muscipula (Venus’s Fly-trap)

T. Isobe, Takehiro Suzuki, N. Dohmae, 2011, Bioscience, biotechnology, and biochemistry.

Synthesis and Biological Evaluation of (S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acids: A Novel Series of PPARγ Agonists

Kenji Takahashi, C. Mukai, Satoru Azukizawa, 2008 .

Specific Inhibition and Stabilization of Aspergilloglutamic Peptidase by the Propeptide

M. Kojima, Kenji Takahashi, K. Kubota, 2005, Journal of Biological Chemistry.

Pepsinogens I and II in Gastric Cancer: An Immunohistochemical Study Using Monoclonal Antibodies

K. Hirano, Kenji Takahashi, M. Ichinose, 1988, Japanese journal of cancer research : Gann.

The Structure and Function of Ribonuclease T1I. Chromatographic Purification and Properties of Ribonuclease T1

Kenji Takahashi, 1961 .

Serum pepsinogens as a screening test of extensive chronic gastritis

Kenji Takahashi, M. Ichinose, K. Miki, 1987, Gastroenterologia Japonica.

13 Ribonuclease T1

S. Moore, Kenji Takahashi, 1982 .

Determination of the NMR Structure of Gln25-Ribonuclease T1

K. Takahashi, M. Tanokura, K. Hatano, 2003, Biological chemistry.

Hemoglobin Izu(Macaca): β83 (EF 7) Gly → Cys. A new hemoglobin variant found in the Japanese monkey (Macaca fuscata)

Shin Nakamura, O. Takenaka, Kenji Takahashi, 1977 .

In situ visualization of caspase‐1‐like activity associated with promotion of hippocampal cell death

Y. Kudo, Takeshi Nakamura, Kenji Takahashi, 2002, FEBS letters.

Reduction of Molten Iron Ore with Solid Carbon

Kenji Takahashi, Masayoshi Amatatsu, T. Sōma, 1975 .

Electron microscopic and biochemical evidence that proline‐β‐naphthylamidase is composed of three identical subunits

A. Ikai, Kenji Takahashi, M. Nishigai, 1991, FEBS letters.

Presence of endogenous inhibitor of aromatic L-amino acid decarboxylase in monkey serum

Kenji Takahashi, T. Nagatsu, A. Togari, 1984, Molecular and Cellular Biochemistry.

Inhibition of rat liver cathepsins B and L by the peptide aldehyde benzyloxycarbonyl-leucyl-leucyl-leucinal and its analogues

Hisashi Ito, Kenji Takahashi, Yong‐Tae Kim, 2009 .

In Situ Localization of Pepsinogens I and II mRNA in Human Gastric Mucosa

M. Ishizaki, G. Asano, Kenji Takahashi, 1989, Acta pathologica japonica.

Biological Activity of Some Cyanobiphenyl Derivatives

I. Kashiwakura, Kazuhito Takeuchi, Kenji Takahashi, 2009 .

Liquid Crystallinity and Biological Activity of a Novel Amphiphilic Compound

I. Kashiwakura, Kenji Takahashi, M. Hazawa, 2009 .

IMPROVED PURIFICATION OF SLOW MOVING PROTEASE FROM HUMAN GASTRIC MUCOSA AND ITS ACTION ON THE B CHAIN OF OXIDIZED BOVINE INSULIN

Kenji Takahashi, O. Matsuzaki, 1988 .

Regioselective arene hydroxylation mediated by a (mu-peroxo)diiron(III) complex: a functional model for toluene monooxygenase.

Kenji Takahashi, S. Fujinami, T. Tosha, 2007, Journal of the American Chemical Society.

Synthesis and biological evaluation of (S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids: a novel series of PPAR gamma agonists.

Kenji Takahashi, C. Mukai, Satoru Azukizawa, 2008, Chemical & pharmaceutical bulletin.

Determination of the complete amino acid sequence of bovine cardiac troponin C.

Kenji Takahashi, J. P. Eerd, 1976 .

Purification and Characterization of a Vasoactive Intestinal Polypeptide-degrading Endoprotease from Porcine Antral Mucosal Membranes (*)

Kenji Takahashi, G. Jeohn, 1995, The Journal of Biological Chemistry.

Hb bali (Macaca) β80 (EF 4) Asn→Lys: The first hemoglobin variant found in the crab-eating monkey (Macaca fascicularis) on Bali Island, Indonesia

Y. Kawamoto, O. Takenaka, Kenji Takahashi, 1985, Primates.

Novel hemoglobin components and their amino acid sequences from the crab-eating macaque (Macaca fascicularis)

O. Takenaka, Kenji Takahashi, A. Takenaka, 2005, Journal of Molecular Evolution.

Functional analysis of the evolutionary conserved arginine 182 residue in human glutathione S‐transferase P1‐1

K. Kong, Kenji Takahashi, H. Inoue, 1997, Biochemistry and molecular biology international.

Novel indoline-based acyl-CoA:cholesterol acyltransferase inhibitor with antiperoxidative activity: improvement of physicochemical properties and biological activities by introduction of carboxylic acid.

M. Ohta, Kenji Takahashi, K. Kunishiro, 2008, Journal of medicinal chemistry.

Mutational analysis of a feruloyl esterase from Aspergillus awamori involved in substrate discrimination and pH dependence.

H. Matsuzawa, K. Hashizume, Kenji Takahashi, 2005, Biochimica et biophysica acta.

Purification and characterization of a novel prolyl endopeptidase from Aspergillus niger

M. Tanokura, Kenji Takahashi, K. Kubota, 2005 .

Hemoglobin Bali (bovine): βA18(Bl)Lys → his: One of the “missing links” between βA and βB of domestic cattle exists in the Bali cattle (Bovinae, Bos banteng)

O. Takenaka, Kenji Takahashi, T. Namikawa, 1983, Biochemical Genetics.

The crystal structure of an intermediate dimer of aspergilloglutamic peptidase that mimics the enzyme-activation product complex produced upon autoproteolysis.

S. Iwata, M. Tanokura, A. Nakagawa, 2012, Journal of biochemistry.

Chapter 26 – Acrocylindropepsin

Kenji Takahashi, 2013 .

The nucleotide and deduced amino acid sequences of porcine liver proline‐β‐naphthylamidase

Kenji Takahashi, H. Inoue, K. Kurokawa, 1991 .

Microtubule assembly from monkey brain microtubule proteins and comparison with porcine brain microtubule assembly system

E. Nishida, H. Sakai, Kenji Takahashi, 1980 .

Tertiary Structure Comparison of Bromelain Inhibitor VI from Pineapple Stem with Bovine Pancreatic Trpsin Inhibitor

M. Tanokura, K. Hatano, Kenji Takahashi, 1996 .

Structure and function studies on enzymes with a catalytic carboxyl group(s): from ribonuclease T1 to carboxyl peptidases

Kenji Takahashi, 2013, Proceedings of the Japan Academy. Series B, Physical and biological sciences.

The effects of mutations in the carboxyl-terminal region on the catalytic activity of Escherichia coli signal peptidase I.

Sun Joo Park, Hisashi Ito, H. Yoshida, 2008, Journal of biochemistry.

The Physarum polycephalum php gene encodes a unique cold‐adapted serine‐carboxyl peptidase, physarolisin II

Kenji Takahashi, W. Nishii, H. Kuriyama, 2003, FEBS letters.

The amino acid sequence of adzuki bean proteinase inhibitor I

Kenji Takahashi, C. Ishikawa, Shin Nakamura, 1979, FEBS letters.

Structural and phylogenetic comparison of three pepsinogens from Pacific bluefin tuna: molecular evolution of fish pepsinogens.

Hisashi Ito, Kenji Takahashi, M. Ichinose, 2009, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Purification and characterization of pepsinogens from the gastric mucosa of African coelacanth, Latimeria chalumnae, and properties of the major pepsins.

Hisashi Ito, S. Yokobori, Kenji Takahashi, 2007, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Tuna pepsinogens and pepsins

Takashi Kageyama, Kenji Takahashi, Masao Tanji, 1988 .

Inhibition of enteropeptidase by antitrypsin drugs

M. Omata, N. Yahagi, Kenji Takahashi, 2001 .

Effect of endotoxin on coagulation , fibrinolysis , kinin forming and complement systems in Japanese monkeys ( M . fuscata fuscata )

J. Nishioka, Koji Suzuki, Shin Nakamura, 2010 .

Experimental disseminated intravascular coagulation (DIC)

J. Nishioka, Koji Suzuki, Shin Nakamura, 1979 .

Design of Wall-Destructive but Membrane-Compatible Solvents.

K. Ninomiya, Y. Tsuge, Kenji Takahashi, 2017, Journal of the American Chemical Society.

Uptake and release of phosphate by a pure culture of Acinetobacter calcoaceticus

H. Ohtake, Y. Tsuzuki, Kenji Takahashi, 1985 .

Purification and Characterization of a Major Collagenase from Streptomyces parvulus

Y. Iino, Masayuki Yamamoto, Kenji Takahashi, 2009, Bioscience, biotechnology, and biochemistry.

A HIGHLY STABLE WATER-INSOLUBLE DERIVATIVE OF RIBONUCLEASE T1

Hisashi Ito, Kenji Takahashi, I. Ichikizaki, 1977 .

Nepenthesin, a unique member of a novel subfamily of aspartic proteinases: enzymatic and structural characteristics.

A. Iwamatsu, Koji Matsumoto, M. Kojima, 2005, Current protein & peptide science.

Isolation and characterization of recombinant Drosophila Copia aspartic proteinase.

K. Yoshioka, T. Shiba, Kenji Takahashi, 2006, The Biochemical journal.

Structural refinement by restrained molecular‐dynamics algorithm with small‐angle X‐ray scattering constraints for a biomolecule

J. Higo, M. Kojima, Kenji Takahashi, 2004 .

Degradation of neuropeptides by cytosolic and cytoskeleton-bound calcium-activated neutral proteases from bovine spinal cord

Kenji Takahashi, Y. Ishizaki, T. Tsubata, 1987 .

Identification of a Glutamic Acid and an Aspartic Acid Residue Essential for Catalytic Activity of Aspergillopepsin II, a Non-pepsin Type Acid Proteinase*

M. Kojima, Kenji Takahashi, H. Inoue, 2000, The Journal of Biological Chemistry.

Cleavage mechanism of ATP‐dependent Lon protease toward ribosomal S2 protein

Kenji Takahashi, T. Muramatsu, Yong‐Tae Kim, 2005, FEBS letters.

Isolation and partial characterization of human and porcine gastric mucins

K. Sutoh, Kenji Takahashi, T. Hase, 1992 .

Ferromagnet (MnAs)/semiconductor (GaAs, AlAs, InAs)/ferromagnet (MnAs) trilayer heterostructures:: Epitaxial growth and magnetotransport properties

Masaaki Tanaka, Kenji Takahashi, 2001 .

N-Linked Oligosaccharides of Aspergillus awamori Feruloyl Esterase Are Important for Thermostability and Catalysis

K. Hashizume, Kenji Takahashi, S. Fushinobu, 2006, Bioscience, biotechnology, and biochemistry.

Chapter 183 – Epralysin

Kenji Takahashi, 2013 .

Bromein, a Bromelain Inhibitor from Pineapple Stem: Structural and Functional Characteristics.

M. Tanokura, K. Hatano, Kenji Takahashi, 2018, Protein Peptide Letters.

Horseshoe crab phylogeny based on amino acid sequences of the fibrino‐peptide‐like peptide C

Shin Nakamura, Kenji Takahashi, K. Sekiguchi, 1982 .

Effect of omeprazole on secretion, synthesis and the gene expression of pepsinogen in the guinea pig stomach mucosa

M. Tatematsu, Kenji Takahashi, P. Nakane, 1994, Cell biochemistry and function.

Kinetic studies of unfolding process of aspergillopepsin II by pH-jump methods.

Y. Amemiya, M. Tanokura, M. Kojima, 2003, Biochemical and biophysical research communications.

Identification and reverse genetic analysis of mitochondrial processing peptidase and the core protein of the cytochrome bc1 complex of Caenorhabditis elegans, a model parasitic nematode.

Kenji Takahashi, H. Inoue, H. Wada, 2006, Journal of biochemistry.

Inhibition of Human Pepsin and Gastricsin by α2-Macroglobulin

A. Ikai, Kenji Takahashi, H. Arakawa, 2003 .

Inhibition of human pepsin and gastricsin by alpha2-macroglobulin.

A. Ikai, Kenji Takahashi, H. Arakawa, 2003, Journal of enzyme inhibition and medicinal chemistry.

Urea-dependent unfolding of HIV-1 protease studied by circular dichroism and small-angle X-ray scattering.

M. Kojima, Kenji Takahashi, H. Inoue, 2009, Biochimica et biophysica acta.

Stability Profiles of Nepenthesin in Urea and Guanidine Hydrochloride: Comparison with Porcine Pepsin A

Kenji Takahashi, K. Kubota, Chiaki Shibata, 2010, Bioscience, biotechnology and biochemistry.

Widespread tissue expression of nepenthesin-like aspartic protease genes in Arabidopsis thaliana.

Kenji Takahashi, H. Inoue, K. Kubota, 2008, Plant physiology and biochemistry : PPB.

Variations in the content and isozymic composition of nepenthesin in the pitcher fluids among Nepenthes species

Kenji Takahashi, M. Tanji, Chiaki Shibata, 2007, Carnivorous Plant Newsletter.

Chapter 24 – Nepenthesin

Kenji Takahashi, 2013 .

Thermal stabilization of ribonuclease T1 by carboxymethylation at Glu‐58 as revealed by 1H nuclear magnetic resonance spectroscopy

M. Tanokura, M. Kojima, T. Mizukoshi, 1994, FEBS Letters.

Crystallization and X-ray diffraction studies of glutathione S-transferase from Escherichia coli

Y. Satow, M. Nishida, Kenji Takahashi, 1996 .

Substrate Specificities of Porcine and Bovine Enteropeptidases toward the Peptide Val-(Asp)4-Lys-Ile-Val-Gly and Its Analogs

Sun Joo Park, Hisashi Ito, Kenji Takahashi, 2008, Bioscience, biotechnology, and biochemistry.

Thermal unfolding of ribonuclease T1 studied by multi-dimensional NMR spectroscopy

S. Shimotakahara, A. Yamagishi, M. Kojima, 2004, Biological chemistry.

Cathepsin L-like cysteine proteases from Brugia malayi: cDNA cloning and comparison with Caenorhabditis elegans

Kenji Takahashi, H. Inoue, Akiko Ukai, 2004 .

PROLYL AMINOPEPTIDASES FROM PIG INTESTINAL MUCOSA AND HUMAN LIVER: PURIFICATION, CHARACTERIZATION AND POSSIBLE IDENTITY WITH LEUCYL AMINOPEPTIDASE

Kenji Takahashi, K. Kurokawa, M. Matsushima, 1991 .

STRUCTURAL AND IHEIJNOLOGICALEVIDENCE FORTHE IDENTITY OF PROLYL AMIINOPEZPTIDASE WITH LEWYL AMINOPEPTIDASE

Kenji Takahashi, K. Kurokawa, K. Miki, 1991 .

Distinct cleavage specificity of human cathepsin E at neutral pH with special preference for Arg-Arg bonds.

Kenji Takahashi, Kenji Takahashi, Senarath B P Athauda, 2002, Protein and peptide letters.

SaxsMDView: a three-dimensional graphics program for displaying force vectors.

T. Nonaka, S. Yanagi, M. Kojima, 2008, Journal of synchrotron radiation.

The Amino Acid Sequence of Ribonuclease T1

Kenji Takahashi, 1965 .

Structural Evidence That Scytalidolisin (Formerly Scytalidopepsin A) Is a Serine-Carboxyl Peptidase of the Sedolisin Family

Kohei Oda, Kenji Takahashi, K. Oda, 2008, Bioscience, biotechnology, and biochemistry.

The unique sites in SulA protein preferentially cleaved by ATP-dependent Lon protease from Escherichia coli.

Kenji Takahashi, T. Maruyama, T. Muramatsu, 2002, European journal of biochemistry.

Structural and phylogenetic comparison of three pepsinogens from Pacific bluefin tuna: molecular evolution of fish pepsinogens.

Hisashi Ito, Kenji Takahashi, M. Ichinose, 2009, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Crystal structure and substrate recognition mechanism of the prolyl endoprotease PEP from Aspergillus niger.

K. Miyazono, M. Tanokura, Kenji Takahashi, 2022, Biochemical and biophysical research communications.

Inhibition and Entrapment of Aspartic Proteinases by α2-Macroglobulin

A. Ikai, Y. Yoshinaka, Kenji Takahashi, 1995 .

Effect of Dimethylsulfoxide on the Crystallization of Aspergillus niger Proteinase A

S. Iwata, M. Tanokura, Kenji Takahashi, 1991 .

Novel tetrahydroisoquinoline derivatives with inhibitory activities against acyl-CoA: cholesterol acyltransferase and lipid peroxidation.

Kenji Takahashi, C. Mukai, Tomohiro Miike, 2010, Chemical & pharmaceutical bulletin.

Novel acyl-CoA: cholesterol acyltransferase inhibitor: indoline-based sulfamide derivatives with low lipophilicity and protein binding ratio.

Kenji Takahashi, Tomohiro Miike, K. Kunishiro, 2010, Chemical & pharmaceutical bulletin.

Novel indoline-based acyl-CoA: cholesterol acyltransferase inhibitor: Effects of introducing a methanesulfonamide group on physicochemical properties and biological activities.

Kenji Takahashi, K. Kunishiro, M. Kasai, 2009, Bioorganic & medicinal chemistry.

Relationships between Lipophilicity and Biological Activities in a Series of Indoline-based Anti-oxidative Acyl-CoA:Cholesterol Acyltransferase (ACAT) Inhibitors

Kenji Takahashi, Tomohiro Miike, K. Kunishiro, 2008, Arzneimittel-Forschung (Drug Research).

Urea-dependent unfolding of HIV-1 protease studied by circular dichroism and small-angle X-ray scattering.

M. Kojima, Kenji Takahashi, H. Inoue, 2009, Biochimica et biophysica acta.

Cathepsin D from Japanese monkey skeletal muscle : an efficient and high-yield purification and some properties

Kenji Takahashi, T. Kageyama, M. Tanji, 1991 .