Y. Tse‐Dinh

发表

Isolation and Quantitation of Topoisomerase Complexes Accumulated on Escherichia coli Chromosomal DNA

Sandra J. Aedo, S. Aedo, Y. Tse‐Dinh, 2012, Antimicrobial Agents and Chemotherapy.

Evaluation of topotecan and etoposide for non‐hodgkin lymphoma

J. Nair, Y. Tse‐Dinh, R. Kancherla, 2001, Cancer.

Holliday junction crossover topology.

N. Seeman, T. Fu, Y. Tse‐Dinh, 1994, Journal of molecular biology.

Mechanistic studies on E. coli DNA topoisomerase I: divalent ion effects.

Y. Tse‐Dinh, P. Domanico, 1991, Journal of inorganic biochemistry.

Cleavage of dT8 and dT8 phosphorothioyl analogues by Escherichia coli DNA topoisomerase I: product and rate analysis.

Y. Tse‐Dinh, P. Domanico, 1988, Biochemistry.

Identification of Anziaic Acid, a Lichen Depside from Hypotrachyna sp., as a New Topoisomerase Poison Inhibitor

J. Clardy, G. Tamayo-Castillo, Y. Tse‐Dinh, 2013, PloS one.

Role of MRP transporters in regulating antimicrobial drug inefficacy and oxidative stress-induced pathogenesis during HIV-1 and TB infections

D. Mondal, E. Batrakova, Y. Tse‐Dinh, 2015, Front. Microbiol..

Synthesizing topological structures containing RNA

Y. Weizmann, J. Piccirilli, Y. Tse‐Dinh, 2017, Nature Communications.

Exploring DNA topoisomerases as targets of novel therapeutic agents in the treatment of infectious diseases.

Y. Tse‐Dinh, 2007, Infectious disorders drug targets.

Evidence for Inhibition of Topoisomerase 1A by Gold(III) Macrocycles and Chelates Targeting Mycobacterium tuberculosis and Mycobacterium abscessus

L. Shaw, Y. Tse‐Dinh, Rashmi Gupta, 2018, Antimicrobial Agents and Chemotherapy.

Targeting bacterial topoisomerases: how to counter mechanisms of resistance.

Y. Tse‐Dinh, 2016, Future medicinal chemistry.

RNase H overproduction allows the expression of stress-induced genes in the absence of topoisomerase I.

T. V. Van Dyk, Y. Tse‐Dinh, B. Cheng, 2003, FEMS microbiology letters.

Differential expression of human topoisomerase IIIalpha during the cell cycle progression in HL-60 leukemia cells and human peripheral blood lymphocytes.

Z. Darżynkiewicz, F. Traganos, X. Li, 2000, Experimental cell research.

Changes in lipid distribution in E. coli strains in response to norfloxacin.

F. Fernandez-Lima, Y. Tse‐Dinh, C. Thompson, 2015, Journal of mass spectrometry : JMS.

Insights from the Structure of Mycobacterium tuberculosis Topoisomerase I with a Novel Protein Fold.

A. Joachimiak, K. Tan, Y. Tse‐Dinh, 2016, Journal of molecular biology.

Antimicrobial Susceptibility and SOS-Dependent Increase in Mutation Frequency Are Impacted by Escherichia coli Topoisomerase I C-Terminal Point Mutation

Jenny J. Yang, Y. Tse‐Dinh, B. Cheng, 2015, Antimicrobial Agents and Chemotherapy.

Mechanistic insights from structure of Mycobacterium smegmatis topoisomerase I with ssDNA bound to both N- and C-terminal domains

K. Tan, X. Zuo, Y. Tse‐Dinh, 2020, Nucleic acids research.

Synthesis, Structure–Activity Relationship Studies, and Antibacterial Evaluation of 4-Chromanones and Chalcones, as Well as Olympicin A and Derivatives

Li Feng, Y. Tse‐Dinh, Dianqing Sun, 2014, Journal of medicinal chemistry.

Distinct Mechanism Evolved for Mycobacterial RNA Polymerase and Topoisomerase I Protein-Protein Interaction.

Y. Tse‐Dinh, Srikanth Banda, N. Cao, 2017, Journal of molecular biology.

Inhibition of Zn(II) Binding Type IA Topoisomerases by Organomercury Compounds and Hg(II)

Y. Tse‐Dinh, B. Cheng, T. Annamalai, 2015, PloS one.

Biochemistry of bacterial type I DNA topoisomerases.

Y. Tse‐Dinh, 1994, Advances in pharmacology.

Escherichia coli DNA topoisomerase I is a zinc metalloprotein with three repetitive zinc-binding domains.

Y. Tse‐Dinh, R. K. Beran-Steed, R. Beran‐Steed, 1988, The Journal of biological chemistry.

Increased Sensitivity to Oxidative Challenges Associated with topA Deletion in Escherichia coli

Y. Tse‐Dinh, 2000, Journal of bacteriology.

Vaccinia virus DNA topoisomerase I preferentially removes positive supercoils from DNA

Y. Tse‐Dinh, M. Fernandez-Beros, Maria-Elena Fernandez-Beros, 1996, FEBS letters.

Light-induced modifications of DNA by gilvocarcin V and its aglycone.

Y. Tse‐Dinh, L. McGee, 1987, Biochemical and biophysical research communications.

Tyrosyl-DNA Phosphodiesterase 1 and Topoisomerase I Activities as Predictive Indicators for Glioblastoma Susceptibility to Genotoxic Agents

W. Reinhold, Y. Pommier, Y. Tse‐Dinh, 2019, bioRxiv.

Conditional growth of Escherichia coli caused by expression of vaccinia virus DNA topoisomerase I

Y. Tse‐Dinh, M. Fernandez-Beros, 1992, Journal of bacteriology.

The DNA relaxation activity and covalent complex accumulation of Mycobacterium tuberculosis topoisomerase I can be assayed in Escherichia coli: application for identification of potential FRET-dye labeling sites

Y. Tse‐Dinh, G. Narula, B. Cheng, 2010, BMC Biochemistry.

DNA supercoiling and bacterial adaptation: thermotolerance and thermoresistance.

Y. Tse‐Dinh, R. Menzel, H. Qi, 1997, Trends in microbiology.

Microbial resistance: Novel screens for a contemporary problem

P. Fernandes, Y. Tse‐Dinh, D. Hardy, 1999, Medicinal research reviews.

Biochemical Basis of E. coli Topoisomerase I Relaxation Activity Reduction by Nonenzymatic Lysine Acetylation

F. Fernandez-Lima, Y. Tse‐Dinh, Qingxuan Zhou, 2018, International journal of molecular sciences.

Synthesis and antibacterial evaluation of anziaic acid and analogues as topoisomerase I inhibitors.

Y. Tse‐Dinh, Dianqing Sun, T. Annamalai, 2013, MedChemComm.

Asp-to-Asn substitution at the first position of the DxD TOPRIM motif of recombinant bacterial topoisomerase I is extremely lethal to E. coli.

Sandra J. Aedo, Y. Tse‐Dinh, B. Cheng, 2009, Journal of molecular biology.

Mutation adjacent to the active site tyrosine can enhance DNA cleavage and cell killing by the TOPRIM Gly to Ser mutant of bacterial topoisomerase I

Y. Tse‐Dinh, B. Cheng, Elena P. Sorokin, 2007, Nucleic acids research.

Increased thermosensitivity associated with topoisomerase I deletion and promoter mutations in Escherichia coli.

Y. Tse‐Dinh, R. Menzel, H. Qi, 1999, FEMS microbiology letters.

Proton Motive Force-Disrupting Antimycobacterial Guanylurea Polymer.

Y. Tse‐Dinh, Sandra E Geden, K. Rohde, 2022, Biomacromolecules.

Supplementary Figure 1 | Construction of the Ssrna Trefoil Knots of Both Handednesses

Y. Weizmann, J. Piccirilli, Y. Tse‐Dinh, 2022 .

Discovery of novel bacterial topoisomerase I inhibitors by use of in silico docking and in vitro assays

Y. Tse‐Dinh, P. Chapagain, Shayna Sandhaus, 2018, Scientific Reports.

A novel copper(II) complex identified as a potent drug against colorectal and breast cancer cells and as a poison inhibitor for human topoisomerase IIα.

N. Seeram, S. Beebe, A. González‐Sarrías, 2016, Inorganic chemistry communications.

Residues of E. coli topoisomerase I conserved for interaction with a specific cytosine base to facilitate DNA cleavage

Y. Tse‐Dinh, G. Narula, 2012, Nucleic acids research.

Virus- and cell-encoded tyrosine protein kinases inactivate DNA topoisomerases in vitro

Y. Tse‐Dinh, T. Wong, A. R. Goldberg, 1984, Nature.

Ungeremine effectively targets mammalian as well as bacterial type I and type II topoisomerases.

Y. Tse‐Dinh, M. Leonti, C. Sissi, 2011, Bioorganic & medicinal chemistry letters.

Localization of Mycobacterium tuberculosis topoisomerase I C-terminal sequence motif required for inhibition by endogenous toxin MazF4

P. Tiwari, Y. Tse‐Dinh, T. Annamalai, 2022, Frontiers in Microbiology.

Synthesis, evaluation, and CoMFA study of fluoroquinophenoxazine derivatives as bacterial topoisomerase IA inhibitors.

Y. Tse‐Dinh, Dianqing Sun, Xufen Yu, 2017, European journal of medicinal chemistry.

Synthesis, characterization, DNA binding, topoisomerase inhibition, and apoptosis induction studies of a novel cobalt(III) complex with a thiosemicarbazone ligand.

S. Beebe, D. Cropek, Y. Tse‐Dinh, 2019, Journal of inorganic biochemistry.

Selective Inhibition of Escherichia coli RNA and DNA Topoisomerase I by Hoechst 33258 Derived Mono- and Bisbenzimidazoles.

Weidong Wang, Souvik Sur, D. Arya, 2017, Journal of medicinal chemistry.

Bacterial topoisomerase I as a target for discovery of antibacterial compounds

Y. Tse‐Dinh, 2008, Nucleic acids research.

Complete nucleotide sequence of the topA gene encoding Escherichia coli DNA topoisomerase I.

J. Wang, Y. Tse‐Dinh, 1986, Journal of molecular biology.

Characterization of molecular interactions between Escherichia coli RNA polymerase and topoisomerase I by molecular simulations

A. Üren, P. Tiwari, Y. Tse‐Dinh, 2016, FEBS letters.

Identification of proximal sites for unwound DNA substrate in Escherichia coli topoisomerase I with oxidative crosslinking

J. Leszyk, Y. Tse‐Dinh, M. Greenberg, 2017, FEBS letters.

Identification of proximal sites for unwound DNA substrate in E . coli topoisomerase I with oxidative crosslinking

J. Leszyk, Y. Tse‐Dinh, M. Greenberg, 2017 .

Structural basis for suppression of hypernegative DNA supercoiling by E. coli topoisomerase I

A. Joachimiak, K. Tan, Zhongtao Zhang, 2015, Nucleic acids research.

Crystal structure of a covalent intermediate in DNA cleavage and rejoining by Escherichia coli DNA topoisomerase I

Zhongtao Zhang, Y. Tse‐Dinh, B. Cheng, 2011, Proceedings of the National Academy of Sciences.

Analysis of DNA relaxation and cleavage activities of recombinant Mycobacterium tuberculosis DNA topoisomerase I from a new expression and purification protocol

Y. Tse‐Dinh, B. Cheng, T. Annamalai, 2009 .

Site-directed Mutagenesis of Residues Involved in G Strand DNA Binding by Escherichia coli DNA Topoisomerase I*

Y. Tse‐Dinh, B. Cheng, Vishwaroop B. Mulay, 2004, Journal of Biological Chemistry.

Solution structure of the C-terminal single-stranded DNA-binding domain of Escherichia coli topoisomerase I.

S. Fesik, Y. Tse‐Dinh, L. Yu, 1995, Biochemistry.

The carboxyl terminal domain of Escherichia coli DNA topoisomerase I confers higher affinity to DNA

Y. Tse‐Dinh, R. Beran‐Steed, 1989, Proteins.

Regulation of the Escherichia coli DNA topoisomerase I gene by DNA supercoiling

Y. Tse‐Dinh, 1985, Nucleic Acids Res..

Inhibition of base excision repair by natamycin suppresses prostate cancer cell proliferation.

I. Agoulnik, Y. Tse‐Dinh, Yuan Liu, 2019, Biochimie.

Topoisomerase 3B (TOP3B) DNA and RNA Cleavage Complexes and Pathway to Repair TOP3B-linked RNA and DNA Breaks

Y. Pommier, Hongliang Zhang, Yilun Sun, 2020, bioRxiv.

SbcCD-Mediated Processing of Covalent Gyrase-DNA Complex in Escherichia coli

Sandra J. Aedo, Y. Tse‐Dinh, 2013, Antimicrobial Agents and Chemotherapy.

Recent Advances in Use of Topoisomerase Inhibitors in Combination Cancer Therapy.

Y. Tse‐Dinh, Wenjie Wang, 2019, Current topics in medicinal chemistry.

Bacterial and archeal type I topoisomerases.

Y. Tse‐Dinh, 1998, Biochimica et biophysica acta.

RNA topoisomerase is prevalent in all domains of life and associates with polyribosomes in animals

M. Gorospe, Y. Pommier, W. Shen, 2016, Nucleic acids research.

Topoisomerase function during bacterial responses to environmental challenge.

Y. Tse‐Dinh, Shang Rui, 2003, Frontiers in bioscience : a journal and virtual library.

Multiple promoters for transcription of the Escherichia coli DNA topoisomerase I gene and their regulation by DNA supercoiling.

Y. Tse‐Dinh, R. Beran, 1988, Journal of molecular biology.

Exonuclease VII repairs quinolone-induced damage by resolving DNA gyrase cleavage complexes

Y. Pommier, N. Majdalani, V. Lamour, 2021, Science Advances.

Compounds with antibacterial activity that enhance DNA cleavage by bacterial DNA topoisomerase I.

Y. Tse‐Dinh, I-Fen Liu, B. Cheng, 2007, The Journal of antimicrobial chemotherapy.

Bacterial Cell Killing Mediated by Topoisomerase I DNA Cleavage Activity*

S. Mukhopadhyay, S. Vasunilashorn, Y. Tse‐Dinh, 2005, Journal of Biological Chemistry.

Type IA Topoisomerases as Targets for Infectious Disease Treatments

Y. Tse‐Dinh, T. Annamalai, Ahmed Seddek, 2021, Microorganisms.

Small-Molecule Inhibitors Targeting Topoisomerase I as Novel Antituberculosis Agents

M. Giulianotti, G. Welmaker, R. Houghten, 2016, Antimicrobial Agents and Chemotherapy.

Identification of a heat shock promoter in the topA gene of Escherichia coli

R. Burgess, S. Lesley, Y. Tse‐Dinh, 1990, Journal of bacteriology.

Regulation of Escherichia coli topA gene transcription: involvement of a sigmaS-dependent promoter.

Y. Tse‐Dinh, R. Menzel, H. Qi, 1997, Journal of molecular biology.

Precision Sports Medicine: The Future of Advancing Health and Performance in Youth and Beyond

Alicia M Montalvo, Alicia M. Montalvo, G. Myer, 2017 .

DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks

Y. Pommier, Hongliang Zhang, Yilun Sun, 2020, Cell reports.

Mechanism of Type IA Topoisomerases

Y. Tse‐Dinh, Tumpa Dasgupta, Shomita Ferdous, 2020, Molecules.

Direct observation of DNA distortion by the RSC complex.

D. Dunlap, T. Owen-Hughes, G. Lia, 2006, Molecular cell.

Investigating mycobacterial topoisomerase I mechanism from the analysis of metal and DNA substrate interactions at the active site

A. Joachimiak, K. Tan, Y. Tse‐Dinh, 2018, Nucleic acids research.

The Strictly Conserved Arg-321 Residue in the Active Site of Escherichia coli Topoisomerase I Plays a Critical Role in DNA Rejoining*

Sandra J. Aedo, Y. Tse‐Dinh, A. Wong, 2011, The Journal of Biological Chemistry.

Inhibition of Mg2+ binding and DNA religation by bacterial topoisomerase I via introduction of an additional positive charge into the active site region

Sandra J. Aedo, Y. Tse‐Dinh, B. Cheng, 2008, Nucleic acids research.

Experimental and computational investigations of Ser10 and Lys13 in the binding and cleavage of DNA substrates by Escherichia coli DNA topoisomerase I

Y. Tse‐Dinh, Chang-Xi Zhu, D. Strahs, 2006, Nucleic acids research.

The role of the Zn(II) binding domain in the mechanism of E. coli DNA topoisomerase I

Y. Tse‐Dinh, A. Ahumada, 2002, BMC Biochemistry.

Effect of phosphorothioate substitutions on DNA cleavage by Escherichia coli DNA topoisomerase I.

Y. Tse‐Dinh, C. Roche, 2001, International journal of biological macromolecules.

The Zn(II) binding motifs of E. coli DNA topoisomerase I is part of a high-affinity DNA binding domain.

Y. Tse‐Dinh, A. Ahumada, 1998, Biochemical and biophysical research communications.

Effect of Mg(II) Binding on the Structure and Activity ofEscherichia coli DNA Topoisomerase I*

Y. Tse‐Dinh, Chang-Xi Zhu, Camille J. Roche, 1997, The Journal of Biological Chemistry.

3,4-dimethoxyphenyl bis-benzimidazole, a novel DNA topoisomerase inhibitor that preferentially targets Escherichia coli topoisomerase I.

V. Tandon, Sandhya Bansal, Y. Tse‐Dinh, 2012, The Journal of antimicrobial chemotherapy.

Analysis of RuvABC and RecG Involvement in the Escherichia coli Response to the Covalent Topoisomerase-DNA Complex

Y. Tse‐Dinh, J. Sutherland, 2010, Journal of bacteriology.

Topoisomerase I function during Escherichia coli response to antibiotics and stress enhances cell killing from stabilization of its cleavage complex.

Y. Tse‐Dinh, J. Sutherland, I-Fen Liu, 2011, The Journal of antimicrobial chemotherapy.

Loss of topoisomerase I function affects the RpoS-dependent and GAD systems of acid resistance in Escherichia coli.

J. Foster, Y. Tse‐Dinh, Devyani Chaudhuri, 2005, Microbiology.

RNase HI overproduction is required for efficient full‐length RNA synthesis in the absence of topoisomerase I in Escherichia coli

Y. Tse‐Dinh, F. Rallu, M. Drolet, 2004, Molecular microbiology.

Direct Interaction between Escherichia coli RNA Polymerase and the Zinc Ribbon Domains of DNA Topoisomerase I*

Y. Tse‐Dinh, Chang-Xi Zhu, A. Ahumada, 2003, Journal of Biological Chemistry.

Effect of the deletion of the σ32‐dependent promoter (P1) of the Escherichia coli topoisomerase I gene on thermotolerance

Y. Tse‐Dinh, R. Menzel, H. Qi, 1996, Molecular microbiology.

Kinetic Study of DNA Topoisomerases by Supercoiling-Dependent Fluorescence Quenching

M. Muller, Z. Hua, F. Leng, 2019, ACS omega.

Mechanistic study of E. coli DNA topoisomerase I: cleavage of oligonucleotides.

Y. Tse‐Dinh, V. Chowdhry, R. Arentzen, 1983, Nucleic acids research.

Deacetylation of topoisomerase I is an important physiological function of E. coli CobB

D. Jin, Y. Tse‐Dinh, Qingxuan Zhou, 2017, Nucleic acids research.

SOS Induction by Stabilized Topoisomerase IA Cleavage Complex Occurs via the RecBCD Pathway

Y. Tse‐Dinh, J. Sutherland, I-Fen Liu, 2008, Journal of bacteriology.

A surface plasmon resonance study of the intermolecular interaction between Escherichia coli topoisomerase I and pBAD/Thio supercoiled plasmid DNA.

P. Tiwari, Y. Tse‐Dinh, Jin He, 2014, Biochemical and biophysical research communications.

Backbone dynamics of the C-terminal domain of Escherichia coli topoisomerase I in the absence and presence of single-stranded DNA.

S. Fesik, Y. Tse‐Dinh, L. Yu, 1996, Biochemistry.

A Yeast-Based Screening System for Differential Identification of Poisons and Suppressors of Human Topoisomerase I.

P. Tiwari, Y. Tse‐Dinh, Aaron Z Welch, 2022, Frontiers in bioscience.

A Yeast-Based Screening System for Differential Identification of Poison Inhibitors and Catalytic Inhibitors of Human Topoisomerase I

P. Tiwari, Y. Tse‐Dinh, Aaron Z Welch, 2021, bioRxiv.

Covalent Complex of DNA and Bacterial Topoisomerase: Implications in Antibacterial Drug Development

A. Üren, P. Tiwari, Y. Tse‐Dinh, 2020, ChemMedChem.

Uncoupling of the DNA breaking and rejoining steps of Escherichia coli type I DNA topoisomerase. Demonstration of an active covalent protein-DNA complex.

Y. Tse‐Dinh, 1986, The Journal of biological chemistry.

Direct Observation of Topoisomerase IA Gate Dynamics

K. Neuman, Maria Mills, Y. Tse‐Dinh, 2018, Nature Structural & Molecular Biology.

Investigating direct interaction between Escherichia coli topoisomerase I and RecA.

P. Tiwari, Y. Tse‐Dinh, Y. Darici, 2016, Gene.

Site-directed Mutagenesis of Conserved Aspartates, Glutamates and Arginines in the Active Site Region of Escherichia coli DNA Topoisomerase I*

Y. Tse‐Dinh, Chang-Xi Zhu, N. Papanicolaou, 1998, The Journal of Biological Chemistry.

Resistance to topoisomerase cleavage complex induced lethality in Escherichia coli via titration of transcription regulators PurR and FNR

Sandra J. Aedo, Y. Tse‐Dinh, I-Fen Liu, 2011, BMC Microbiology.

Hydroxyl Radicals Are Involved in Cell Killing by the Bacterial Topoisomerase I Cleavage Complex

Y. Tse‐Dinh, J. Sutherland, I-Fen Liu, 2009, Journal of bacteriology.

A Fluorescence-Based Assay for Identification of Bacterial Topoisomerase I Poisons.

Y. Tse‐Dinh, B. Cheng, T. Annamalai, 2018, Methods in molecular biology.

Targeting bacterial topoisomerase I to meet the challenge of finding new antibiotics.

Y. Tse‐Dinh, 2015, Future medicinal chemistry.

Action of Topoisomerase Targeting Drugs on Non‐Hodgkin's Lymphoma and Leukemia: Correlation of Clinical and Cell Culture Studies

F. Traganos, J. Nair, Y. Tse‐Dinh, 2000, Annals of the New York Academy of Sciences.

Trapped Ion Mobility Spectrometry of Native Macromolecular Assemblies.

Melvin A. Park, F. Fernandez-Lima, F. Leng, 2021, Analytical chemistry.

Flexibility at Gly-194 Is Required for DNA Cleavage and Relaxation Activity of Escherichia coli DNA Topoisomerase I*

Y. Tse‐Dinh, B. Cheng, Jingyang Feng, 2004, Journal of Biological Chemistry.

The Acidic Triad Conserved in Type IA DNA Topoisomerases Is Required for Binding of Mg(II) and Subsequent Conformational Change*

Y. Tse‐Dinh, Chang-Xi Zhu, 2000, The Journal of Biological Chemistry.

Mutation in Cys662 of Escherichia coli DNA topoisomerase I confers temperature sensitivity and change in DNA cleavage selectivity.

Y. Tse‐Dinh, C. Zhu, H. Qi, 1995, Journal of molecular biology.

Expression and DNA-binding properties of the 14K carboxyl terminal fragment of Escherichia coli DNA topoisomerase I.

Y. Tse‐Dinh, A. Ahumada, A. Pound, 1995, Biochemistry and molecular biology international.

Zinc (II) coordination in Escherichia coli DNA topoisomerase I is required for cleavable complex formation with DNA.

Y. Tse‐Dinh, 1991, Journal of Biological Chemistry.

Overexpression and purification of bacterial DNA topoisomerase I.

Y. Tse‐Dinh, C. Zhu, 1999, Methods in molecular biology.

Biochemical and biophysical properties of positively supercoiled DNA.

Z. Hua, F. Leng, Y. Tse‐Dinh, 2017, Biophysical chemistry.

Microbial Type IA Topoisomerase C-Terminal Domain Sequence Motifs, Distribution and Combination

K. Tan, Y. Tse‐Dinh, Christopher Mederos, 2022, International journal of molecular sciences.

Systematic investigation of crystallization parameters for protein-nucleic acid complexes: application to an active truncated form ofEscherichia coli topoisomerase I

P. Weber, Y. Tse‐Dinh, Chang-Xi Zhu, 1992 .

Mutations of vaccinia virus DNA topoisomerase I that stabilize the cleavage complex.

Y. Tse‐Dinh, M. Gupta, C. Zhu, 1994, The Journal of biological chemistry.

The interaction between transport-segment DNA and topoisomerase IA—crystal structure of MtbTOP1 in complex with both G- and T-segments

K. Tan, Y. Tse‐Dinh, T. Annamalai, 2022, Nucleic acids research.

Microheterogeneity of Topoisomerase IA/IB and Their DNA-Bound States

F. Fernandez-Lima, F. Leng, Y. Tse‐Dinh, 2019, ACS omega.

Metal ion and inter-domain interactions as functional networks in E. coli topoisomerase I.

M. Palumbo, Y. Tse‐Dinh, C. Sissi, 2013, Gene.

Binding of Zn(II) to Escherichia coli DNA topoisomerase I.

Y. Tse‐Dinh, C. Zhu, 1994, Biochemistry and molecular biology international.

An engineered mutant of vaccinia virus DNA topoisomerase I is sensitive to the anti-cancer drug camptothecin.

Y. Tse‐Dinh, M. Gupta, C. Zhu, 1992, The Journal of biological chemistry.

Effect of zinc removal on the conformation of Escherichia coli DNA topoisomerase I.

Y. Tse‐Dinh, C. Zhu, G. Villanueva, 1993, Archives of biochemistry and biophysics.

A diverse global fungal library for drug discovery

Xiaohong Wang, Jun Li, S. Munga, 2020, PeerJ.

Topological transformations of synthetic DNA knots.

N. Seeman, Y. Tse‐Dinh, S. Du, 1995, Biochemistry.

C-TERMINAL DOMAIN OF ESCHERICHIA COLI TOPOISOMERASE I

Liping Yu, S. Fesik, Y. Tse‐Dinh, 1996 .