Karan M. Shah

发表

Decoding the genomic basis of osteoarthritis

E. Zeggini, C. Lelliott, J. Choudhary, 2019, bioRxiv.

Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis

E. Zeggini, G. Ritchie, J. Choudhary, 2016, Scientific Reports.

Genome-wide association study of developmental dysplasia of the hip identifies an association with GDF5

E. Zeggini, K. Hatzikotoulas, A. Wainwright, 2018, Communications Biology.

A Systematic Review of the Expression, Signalling and Function of P2 Receptors in Primary Bone Cancer.

A. Gartland, Karan M. Shah, Luke Tattersall, 2022, Frontiers in bioscience.

A novel prostaglandin E receptor 4 (EP4) small molecule antagonist induces articular cartilage regeneration

Mingyao Liu, Jian Luo, Weiqiang Lu, 2022, Cell discovery.

Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis

E. Zeggini, G. Ritchie, J. Choudhary, 2016, bioRxiv.

Effects of cobalt and chromium ions at clinically equivalent concentrations after metal-on-metal hip replacement on human osteoblasts and osteoclasts: implications for skeletal health.

A. Gartland, J. Wilkinson, Karan M. Shah, 2011, Bone.

JZL184, A Monoacylglycerol Lipase Inhibitor, Induces Bone Loss in a Multiple Myeloma Model of Immunocompetent Mice

Karan M. Shah, S. Marino, D. Lath, 2020, Calcified Tissue International.

Understanding the tissue effects of tribo‐corrosion: Uptake, distribution, and speciation of cobalt and chromium in human bone cells

A. Gartland, J. Wilkinson, P. Quinn, 2015, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

The strategy and clinical relevance of in vitro models of MAP resistance in osteosarcoma: a systematic review

A. Gartland, Karan M. Shah, M. Lawson, 2022, Oncogene.

Cobalt and chromium exposure affects osteoblast function and impairs the mineralization of prosthesis surfaces in vitro

A. Gartland, J. Wilkinson, Karan M. Shah, 2015, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

PGE2 activates EP4 in subchondral bone osteoclasts to regulate osteoarthritis

Mingyao Liu, Jian Luo, Weiqiang Lu, 2022, Bone Research.

Strategies for Articular Cartilage Repair and Regeneration

Karan M. Shah, Yanxi Liu, Jian Luo, 2021, Frontiers in Bioengineering and Biotechnology.

Genome-wide association study of developmental dysplasia of the hip identifies an association with GDF5

E. Zeggini, K. Hatzikotoulas, A. Wainwright, 2018, Communications Biology.

A molecular quantitative trait locus map for osteoarthritis

E. Zeggini, J. Choudhary, L. Southam, 2021, Nature Communications.

The 2018 Otto Aufranc Award: How Does Genome-wide Variation Affect Osteolysis Risk After THA?

E. Zeggini, I. Tachmazidou, K. Hatzikotoulas, 2019, Clinical orthopaedics and related research.

Effects of chronic cobalt and chromium exposure after metal‐on‐metal hip resurfacing: An epigenome‐wide association pilot study

E. Zeggini, A. Gartland, J. Wilkinson, 2017, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

A novel prostaglandin E receptor 4 (EP4) small molecule antagonist induces articular cartilage regeneration

Mingyao Liu, Jian Luo, Weiqiang Lu, 2022, Cell Discovery.

P2RX7 inhibition reduces breast cancer induced osteolytic lesions - implications for bone metastasis

J. Erler, A. Gartland, Karan M. Shah, 2022, bioRxiv.

The Genetic Epidemiology of Developmental Dysplasia of the Hip: A Genome-Wide Association Study Harnessing National Clinical Audit Data

E. Zeggini, K. Hatzikotoulas, D. Eastwood, 2017, bioRxiv.

JZL184, A Monoacylglycerol Lipase Inhibitor, Induces Bone Loss in a Multiple Myeloma Model of Immunocompetent Mice

Karan M. Shah, S. Marino, D. Lath, 2020, Calcified Tissue International.

The P2RX7B splice variant modulates osteosarcoma cell behaviour and metastatic properties

F. Di Virgilio, W. Fraser, A. Gartland, 2021, bioRxiv.

YBX1-interacting small RNAs and RUNX2 can be blocked in primary bone cancer using CADD522

W. Fraser, A. Gartland, D. Elliott, 2023, Journal of bone oncology.

Linking chondrocyte and synovial transcriptional profile to clinical phenotype in osteoarthritis

E. Zeggini, L. Southam, R. Brooks, 2021, Annals of the Rheumatic Diseases.

Osteocyte physiology and response to fluid shear stress are impaired following exposure to cobalt and chromium: Implications for bone health following joint replacement

A. Gartland, J. Wilkinson, N. Mani, 2016, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Osteocyte isolation and culture methods.

M. Stern, Karan M. Shah, A. Bakker, 2016, BoneKEy reports.

Distinct Concentration-Dependent Molecular Pathways Regulate Bone Cell Responses to Cobalt and Chromium Exposure from Joint Replacement Prostheses

M. Dunning, A. Gartland, J. Wilkinson, 2021, International journal of molecular sciences.

GPRC5B protects osteoarthritis by regulation of autophagy signaling

Mingyao Liu, Karan M. Shah, Jingduo Gao, 2023, Acta pharmaceutica Sinica. B.