M. Malissen

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Precise Temporal Profiling of Signaling Complexes in Primary Cells Using SWATH Mass Spectrometry

Ben C. Collins, H. Kitano, R. Aebersold, 2017, Cell reports.

Pathogenic roles and therapeutic potential of the CCL8–CCR8 axis in a murine model of IgG4-related sialadenitis

I. Matsumoto, T. Sumida, B. Malissen, 2021, Arthritis Research & Therapy.

The lymphoid lineage–specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells

B. Malissen, I. Nijman, J. Imbert, 2013, Nature Immunology.

Mouse T cell antigen receptor: Structure and organization of constant and joining gene segments encoding the β polypeptide

Tak W. Mak, Marie Malissen, Tim Hunkapiller, 1984, Cell.

T-cell-specific deletion of T-cell receptor transgenes allows functional rearrangement of endogenous alpha- and beta-genes.

A. Berns, Y. Uematsu, M. Malissen, 1988, Nature.

The joining of germ-line V alpha to J alpha genes replaces the preexisting V alpha-J alpha complexes in a T cell receptor alpha, beta positive T cell line.

P. Cazenave, K. Marcu, J. Fondell, 1988, Cell.

Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor.

P. Perrin, R. Locksley, M. Mingueneau, 2009, Immunity.

Lymphoproliferative disorders involving T helper effector cells with defective LAT signalosomes

M. Mingueneau, B. Malissen, R. Roncagalli, 2010, Seminars in Immunopathology.

LAT signaling pathology: an "autoimmune" condition without T cell self-reactivity.

M. Mingueneau, B. Malissen, R. Roncagalli, 2010, Trends in immunology.

Dominant Role of CD80–CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LATY136F CD4+ T Cells

Stéphane Chevrier, B. Malissen, H. Acha‐Orbea, 2012, Front. Immun..

Function of the CD3 subunits of the pre-TCR and TCR complexes during T cell development.

B. Malissen, M. Malissen, S. Y. Lin, 1999, Advances in immunology.

intraepithelial lymphocytes + gut δ γ early T- and B-cell development and a reduction in T-cell receptor Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of

M. Nussenzweig, E. Meffre, A. Carrier, 2013 .

Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of early T- and B-cell development and a reduction in T-cell receptor γδ+ gut intraepithelial lymphocytes

M. Nussenzweig, E. Meffre, A. Carrier, 2001 .

Non-T Cell Activation Linker Promotes Mast Cell Survival by Dampening the Recruitment of SHIP1 by Linker for Activation of T Cells1

B. Malissen, M. Malissen, K. Roget, 2008, The Journal of Immunology.

Selective Defect in Antigen-Induced TCR Internalization at the Immune Synapse of CD8 T Cells Bearing the ZAP-70(Y292F) Mutation1

B. Malissen, J. Leignadier, P. Soubeyran, 2005, The Journal of Immunology.

Mutation CD 8 T Cells Bearing the ZAP-70 ( Y 292 F ) Internalization at the Immune Synapse of Selective Defect in Antigen-Induced TCR

B. Malissen, J. Leignadier, P. Soubeyran, 2005 .

Crippling of CD3-ζ ITAMs Does Not Impair T Cell Receptor Signaling

A. Trautmann, B. Malissen, J. Nunès, 1999 .

Th2 Lymphoproliferative Disorder of LatY136F Mutant Mice Unfolds Independently of TCR-MHC Engagement and Is Insensitive to the Action of Foxp3+ Regulatory T Cells1

P. Perrin, M. Mingueneau, Stéphane Chevrier, 2008, The Journal of Immunology.

T Cell Development and T Cell Responses in Mice with Mutations Affecting Tyrosines 292 or 315 of the Zap-70 Protein Tyrosine Kinase

C. Arrieumerlou, B. Malissen, O. Acuto, 2001, The Journal of experimental medicine.

CD93 is required for maintenance of antibody secretion and persistence of plasma cells in the bone marrow niche

L. Otten, Stéphane Chevrier, S. Nutt, 2009, Proceedings of the National Academy of Sciences.

Tyrosine 315 determines optimal recruitment of ZAP‐70 to the T cell antigen receptor

B. Malissen, O. Acuto, M. Malissen, 2002, European journal of immunology.

Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor–independent TCR signaling hub

H. Lähdesmäki, R. Aebersold, R. Lahesmaa, 2014, Nature Immunology.

DelK32-lamin A/C has abnormal location and induces incomplete tissue maturation and severe metabolic defects leading to premature death.

T. Arimura, E. Lacène, M. Malissen, 2012, Human molecular genetics.

Excessive immunosuppression by regulatory T cells antagonizes T cell response to schistosome infection in PD-1-deficient mice

B. Malissen, M. Malissen, Binhui Zhou, 2022, PLoS pathogens.

Tyrosine Kinase Expression for the Down-Regulation of Syk Protein PreT Cell Receptor Signals Are Responsible

A. Weiss, M. Malissen, M. Elder, 1999 .

Pre-T cell receptor signals are responsible for the down-regulation of Syk protein tyrosine kinase expression.

A. Weiss, M. Malissen, M. Elder, 1999, Journal of immunology.

Functions of TCR and pre-TCR subunits: lessons from gene ablation.

B. Malissen, M. Malissen, 1996, Current opinion in immunology.

SHIP 1 by Linker for Activation of T Cells Cell Survival by Dampening the Recruitment Non-T Cell Activation Linker Promotes

B. Malissen, M. Malissen, K. Roget, 2008 .

STAT6 Deletion Converts the Th2 Inflammatory Pathology Afflicting LatY136F Mice into a Lymphoproliferative Disorder Involving Th1 and CD8 Effector T Cells1

E. Devilard, M. Mingueneau, G. Delsol, 2009, The Journal of Immunology.

Involving Th 1 and CD 8 Effector T Cells Mice into a Lymphoproliferative Disorder Y 136 FLat Inflammatory Pathology Afflicting STAT 6 Deletion Converts the Th 2 Malissen and

E. Devilard, M. Mingueneau, G. Delsol, 2009 .

Mechanisms of Peripheral Tolerance

G. Schönrich, B. Malissen, F. Momburg, 1993 .

Non‐Deletional Mechanisms of Peripheral and Central Tolerance: Studies with Transgenic Mice with Tissue‐Specific Expression of a Foreign MHC Class I Antigen

G. Schönrich, B. Malissen, F. Momburg, 1991, Immunological reviews.

A hypomorphic allele of ZAP-70 reveals a distinct thymic threshold for autoimmune disease versus autoimmune reactivity

A. Weiss, M. Malissen, Lih-Yun Hsu, 2009, The Journal of experimental medicine.

Induction of T Helper Type 2 Immunity by a Point Mutation in the LAT Adaptor

B. Malissen, M. Malissen, Xiao-jun Guo, 2002, Science.

HLA Class I Genes: From Structure to Expression, Serology and Function

T. Strachan, F. Lemonnier, R. Sodoyer, 1985, Immunological reviews.

Role of the LAT adaptor in T-cell development and Th2 differentiation.

B. Malissen, M. Malissen, E. Aguado, 2005, Advances in immunology.

Cell Activation and Systemic Autoimmunity Mutant Mice Triggers Polyclonal B Y136F Lat The Th2 Lymphoproliferation Developing in

G. Delsol, B. Malissen, H. Acha‐Orbea, 2006 .

The Th2 Lymphoproliferation Developing in LatY136F Mutant Mice Triggers Polyclonal B Cell Activation and Systemic Autoimmunity1

G. Delsol, B. Malissen, H. Acha‐Orbea, 2006, The Journal of Immunology.

Exon/intron organization and complete nucleotide sequence of an HLA gene.

B. Malissen, M. Malissen, B. Jordan, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Tuning of Natural Killer Cell Reactivity by NKp46 and Helios Calibrates T Cell Responses

Baptiste N. Jaeger, J. Estellé, S. Heath, 2012, Science.

Multiplicity and plasticity of natural killer cell signaling pathways.

M. Mingueneau, B. Malissen, É. Vivier, 2006, Blood.

HLA cosmid clones show complete, widely spaced human class I genes with occasional clusters.

D. Birnbaum, M. Malissen, B. Jordan, 1982, Gene.

Genetic Dissection of the Transducing Subunits of the T‐Cell Antigen Receptor

B. Malissen, É. Vivier, M. Malissen, 1995, Annals of the New York Academy of Sciences.

Analysis of the individual role of the TCRzeta chain in transgenic mice after conditional activation with chemical inducers of dimerization.

L. Berg, M. Malissen, G. Soldevila, 2001, Cellular immunology.

The Type 1 Cysteinyl Leukotriene Receptor Triggers Calcium Influx and Chemotaxis in Mouse αβ- and γδ Effector T Cells1

H. Mollenkopf, S. Kaufmann, B. Malissen, 2005, The Journal of Immunology.

Diversity of innate immune cell subsets across spatial and temporal scales in an EAE mouse model

Keith K. Fenrich, G. Rougon, H. Luche, 2018, Scientific Reports.

Effects of VEGF blockade on the dynamics of the inflammatory landscape in glioblastoma-bearing mice

G. Rougon, M. Malissen, S. Brustlein, 2019, Journal of Neuroinflammation.

Roles of the C-terminal tyrosine residues of LAT in GPVI-induced platelet activation: insights into the mechanism of PLC gamma 2 activation.

B. Malissen, B. Payrastre, M. Malissen, 2007, Blood.

Single and Combined Deletions of the NTAL/LAB and LAT Adaptors Minimally Affect B-Cell Development and Function

B. Malissen, B. Schraven, J. Špička, 2005, Molecular and Cellular Biology.

The CD3-γδε and CD3-ζ/η Modules Are Each Essential for Allelic Exclusion at the T Cell Receptor β Locus but Are Both Dispensable for the Initiation of V to (D)J Recombination at the T Cell Receptor–β, –γ, and –δ Loci

B. Malissen, M. Malissen, L. Ardouin, 1998, The Journal of experimental medicine.

The Common Cytokine Receptor γ Chain Controls Survival of γ/δ T Cells

P. Pereira, D. Gerber, B. Malissen, 1997, The Journal of experimental medicine.

The Common Cytokine Receptor g Chain Controls Survival of g / d T Cells

P. Pereira, D. Gerber, B. Malissen, 1997 .

Altered T cell development in mice with a targeted mutation of the CD3‐epsilon gene.

B. Malissen, P. Ferrier, É. Vivier, 1995, The EMBO journal.

T-cell-specific deletion of T-cell receptor transgenes allows functional rearrangement of endogenous α- and β-genes

A. Berns, Y. Uematsu, M. Malissen, 1988, Nature.

Thymocytes and RelB‐dependent medullary epithelial cells provide growth‐promoting and organization signals, respectively, to thymic medullary stromal cells

M. Aurrand-Lions, M. Malissen, P. Naquet, 1997, European journal of immunology.

Expression of human class I histocompatibility antigens at the surface of DNA-transformed mouse L cells

D. Birnbaum, F. Lemonnier, P. Golstein, 2004, Immunogenetics.

LatY136F knock-in mouse model for human IgG4-related disease

B. Malissen, Masahiko Zuka, T. Onoe, 2018, PloS one.

Transformation of LMTK− cells with purified HLA class I genes

F. Lemonnier, P. Dubreuil, A. Svejgaard, 1983, Immunogenetics.

The transcriptional repressor Gfi1 prevents lupus autoimmunity by restraining TLR7 signaling

B. Malissen, P. Bruhns, L. Alexopoulou, 2016, European journal of immunology.

T cell development in mice lacking the CD3‐zeta/eta gene.

E. Spanopoulou, B. Rocha, É. Vivier, 1993, EMBO Journal.

Replacement of Pre-T Cell Receptor Signaling Functions by the CD4 Coreceptor

R. Perlmutter, K. Forbush, M. Malissen, 1997, The Journal of experimental medicine.

Replacement of PreT Cell Receptor Signaling Functions by the CD 4 Coreceptor

R. Perlmutter, K. Forbush, M. Malissen, 1996 .

Definitive Report : CD 6 modulates thymocyte selection and peripheral T cell homeostasis

B. Malissen, R. Vicente, Amado Carreras-Sureda, 2017 .

CD6 modulates thymocyte selection and peripheral T cell homeostasis

B. Malissen, R. Vicente, Amado Carreras-Sureda, 2016, The Journal of experimental medicine.

In the absence of its cytosolic domain, the CD28 molecule still contributes to T cell activation

D. Olive, J. Mege, J. Nunès, 2015, Cellular and Molecular Life Sciences.

Each of the two productive T cell receptor α-gene rearrangements found in both the A10 and BM 3.3 T cell clones give rise to an α chain which can contribute to the constitution of a surface-expressed αβ dimer

B. Malissen, M. Malissen, A. Schmitt‐Verhulst, 1991 .

Regulation of TCR alpha and beta gene allelic exclusion during T-cell development.

B. Malissen, P. Cazenave, M. Malissen, 1992, Immunology today.

Distinct mechanisms of extrathymic T cell tolerance due to differential expression of self antigen.

G. Schönrich, B. Malissen, F. Momburg, 1992, International immunology.

The Single Positive T Cells Found in CD3-ζ/η− /− Mice Overtly React with Self–Major Histocompatibility Complex Molecules upon Restoration of Normal Surface Density of T Cell Receptor–CD3 Complex

B. Malissen, M. Malissen, L. Ardouin, 1997, The Journal of experimental medicine.

The joining of germ-line Vα to Jα genes replaces the preexisting Vα-Jα complexes in a T cell receptor α,β positive T cell line

P. Cazenave, K. Marcu, J. Fondell, 1988, Cell.

Cell Receptor g Gene Regulatory Sequences Prevent the Function of a Novel TCR g / pT a Pre – T Cell Receptor

C. Laplace, Joonsoo Kang, H. Fehling, 1998 .

A hypomorphic mutation in the Gfi1 transcriptional repressor results in a novel form of neutropenia

M. D. de Angelis, B. Malissen, P. Bruhns, 2012, European journal of immunology.

A novel form of mouse neutropenia resulting from a point mutation in the zinc finger protein Gfi1

B. Malissen, P. Bruhns, Weidong Zhao, 2012 .

Reply to "Neutrophils are not required for resolution of acute gouty arthritis in mice"

A. Mócsai, G. Schett, M. Herrmann, 2016, Nature Medicine.

Rapid Sequestration of Leishmania mexicana by Neutrophils Contributes to the Development of Chronic Lesion

B. Malissen, H. Simon, S. Yousefi, 2015, PLoS pathogens.

Neutrophils Exert a Suppressive Effect on Th1 Responses to Intracellular Pathogen Brucella abortus

H. Lepidi, Anna R Martirosyan, B. Malissen, 2013, PLoS pathogens.

Negative Regulation of Mast Cell Signaling and Function by the Adaptor LAB/NTAL

B. Malissen, P. Heneberg, M. Boubelík, 2004, The Journal of experimental medicine.

Multiple C4/Slp genes distinguished by expression after transfection

L. Hood, A. Ferreira, M. Malissen, 1986, Molecular and cellular biology.

LAT regulates gammadelta T cell homeostasis and differentiation.

L. Xerri, B. Chetaille, B. Malissen, 2003, Nature immunology.

Use of TCR ADV gene segments by the δ chain is independent of their position and of CD3 expression

S. Candéias, M. Malissen, P. Marche, 1998, European journal of immunology.

Expression of human histocompatibility antigens on the surface of murine cells transformed by cosmid clones containing HLA genes.

F. Lemonnier, P. Golstein, P. Le Bouteiller, 1982, Experimental cell research.

T Cell Receptor γ Gene Regulatory Sequences Prevent the Function of a Novel TCRγ/pTα Pre–T Cell Receptor

C. Laplace, Joonsoo Kang, H. Fehling, 1998 .

Neutrophils enhance early Trypanosoma brucei infection onset

P. De Baetselier, M. Mazzone, S. Magez, 2018, Scientific Reports.

Genomic organization of the mouse T cell receptor V alpha family.

B. Malissen, I. Hue, M. Malissen, 1990, The EMBO journal.

Isolation and Characterization of I Region Genes from the Major Histocompatibility Complex of the Mouse

L. Hood, B. Mach, A. Winoto, 1983 .

The tight interallelic positional coincidence that distinguishes T-cell receptor Jalpha usage does not result from homologous chromosomal pairing during ValphaJalpha rearrangement.

J. Casanova, A. Nussenzweig, M. Bonneville, 2001, The EMBO journal.

Complexity, polymorphism, and recombination of mouse T-cell receptor alpha gene families.

N. Trede, P. Cazenave, I. Hue, 1989, Immunogenetics.

Normal development and function of natural killer cells in CD3 epsilon delta 5/delta 5 mutant mice.

B. Malissen, G. Milon, É. Vivier, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Differential effects of manipulating signaling in early T cell development in intestinal intraepithelial lymphocytes and thymocytes.

R. Perlmutter, L. Bogatzki, M. Malissen, 1999, International immunology.

ARHGAP45 controls naïve T‐ and B‐cell entry into lymph nodes and T‐cell progenitor thymus seeding

Even Fossum, B. Malissen, S. Audebert, 2021, EMBO reports.

A novel model for treatment of hypertrophic pachymeningitis

J. Kira, B. Malissen, M. Kawano, 2019, Annals of clinical and translational neurology.

Complexity, polymorphism, and recombination of mouse T-cell receptor α gene families

N. Trede, P. Cazenave, I. Hue, 2006, Immunogenetics.

Sox17 Regulates Liver Lipid Metabolism and Adaptation to Fasting

B. Beutler, B. Malissen, J. Imbert, 2014, PloS one.

Impaired Accumulation of Antigen-Specific CD8 Lymphocytes in Chemokine CCL25-Deficient Intestinal Epithelium and Lamina Propria1

James J. Campbell, B. Malissen, M. Malissen, 2007, The Journal of Immunology.

Lamina Propria CCL25-Deficient Intestinal Epithelium and CD8 Lymphocytes in Chemokine Impaired Accumulation of Antigen-Specific

James J. Campbell, B. Malissen, M. Malissen, 2007 .

Intestinal intraepithelial lymphocytes include precursors committed to the T cell receptor αβ lineage

R. Perlmutter, L. Bogatzki, M. Malissen, 1998 .

Differential gene expression in CD3e- and RAG1-deficient thymuses: definition of a set of genes potentially involved in thymocyte maturation

S. Granjeaud, B. Malissen, P. Ferrier, 1999, Immunogenetics.

Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of early T- and B-cell development and a reduction in T-cell receptor gammadelta(+) gut intraepithelial lymphocytes.

M. Nussenzweig, E. Meffre, A. Carrier, 2001, Blood.

Mannosidase I inhibition rescues the human alpha-sarcoglycan R77C recurrent mutation.

I. Richard, B. Malissen, O. Danos, 2008, Human molecular genetics.

Gene Knock-in by CRISPR/Cas9 and Cell Sorting in Macrophage and T Cell Lines

M. Malissen, Yinming Liang, Le He, 2021, Journal of Visualized Experiments.

Non–T Cell Activation Linker (NTAL)

Naděžda Brdičková, B. Schraven, J. Špička, 2002, The Journal of experimental medicine.

Unveiling skin macrophage dynamics explains both tattoo persistence and strenuous removal

M. Bajénoff, P. Benaroch, B. Malissen, 2018, The Journal of experimental medicine.

Diversity of innate immune cell subsets across spatial and temporal scales in an EAE mouse model

Keith K. Fenrich, G. Rougon, H. Luche, 2018, Scientific Reports.

Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction

G. Schönrich, B. Malissen, F. Momburg, 1991, Cell.

Tracts of high or low sequence divergence in the mouse major histocompatibility complex.

Ryszard S. Romaniuk, L. Hood, R. Maki, 1984, The EMBO journal.

Early T‐cell Development in CD3‐deficient Mice

B. Malissen, M. Malissen, A. Magnan, 1995, Immunological reviews.

Regulation of TCR α and β gene allelic exclusion during T-cell development

B. Malissen, P. Cazenave, M. Malissen, 1992 .

A T cell clone expresses two T cell receptor α genes but uses one αβ heterodimer for allorecognition and self MHC-restricted antigen recognition

L. Hood, B. Malissen, M. Malissen, 1988, Cell.

The scaffolding function of the RLTPR protein explains its essential role for CD28 co-stimulation in mouse and human T cells

B. Malissen, S. Audebert, L. Camoin, 2016, The Journal of experimental medicine.

Dual T cell– and B cell–intrinsic deficiency in humans with biallelic RLTPR mutations

J. Casanova, L. Notarangelo, E. Crestani, 2016, The Journal of experimental medicine.

The human t cell antigen receptor is encoded by variable, diversity, and joining gene segments that rearrange to generate a complete V gene

L. Hood, T. Mak, Y. Yoshikai, 1984, Cell.

ImmGen at 15

Jason D. Buenrostro, E. Amir, A. Regev, 2020, Nature Immunology.

The chemokine TECK is expressed by thymic and intestinal epithelial cells and attracts double‐ and single‐positive thymocytes expressing the TECK receptor CCR9

Marie Malissen, Bernard Malissen, M. Mattei, 2000, European journal of immunology.

Germline genomic structure of the B10.A mouseTcra-V2 gene subfamily

B. Malissen, P. Cazenave, A. Six, 2007, Immunogenetics.

Phenotypic dynamics of microglial and monocyte-derived cells in glioblastoma-bearing mice

D. Figarella-Branger, G. Rougon, H. Luche, 2016, Scientific Reports.

Direct evidence for chromosomal inversion during T-cell receptor β-gene rearrangements

L. Hood, B. Malissen, M. Malissen, 1986, Nature.

Rapid in vivo analysis of mutant forms of the LAT adaptor using Pax5‐Lat double‐deficient pro‐B cells

M. Busslinger, B. Malissen, A. Rolink, 2005, European journal of immunology.

Linker for Activation of T Cells Integrates Positive and Negative Signaling in Mast Cells1

W. Fridman, B. Malissen, M. Malissen, 2004, The Journal of Immunology.

Positive and Negative Signaling in Mast Cells Linker for Activation of T Cells Integrates

B. Malissen, M. Malissen, M. Daëron, 2004 .

The T cell receptor β chain genes are located on chromosome 6 in mice and chromosome 7 in humans

L. Hood, T. Mak, J. Goverman, 1984, Cell.

Rearrangement and transcription of the β-chain genes of the T-cell antigen receptor in different types of murine lymphocytes

L. Hood, J. Goverman, M. Kronenberg, 1985, Nature.

Visualization of the earliest steps of gammadelta T cell development in the adult thymus.

B. Malissen, A. Kissenpfennig, I. Prinz, 2006, Nature immunology.

Tumor-associated neutrophils suppress pro-tumoral IL-17+ γδ T cells through induction of oxidative stress

H. Kubo, B. Silva-Santos, M. Malissen, 2018, PLoS biology.

Atp6ap2 ablation in adult mice impairs viability through multiple organ deficiencies

Y. Hérault, T. Sorg, M. Champy, 2017, Scientific Reports.

Neutrophil depletion impairs natural killer cell maturation, function, and homeostasis

Baptiste N. Jaeger, M. Bajénoff, B. Malissen, 2012, The Journal of experimental medicine.

Innate Immune Basis for Rift Valley Fever Susceptibility in Mouse Models

P. Bruhns, G. Jouvion, M. Malissen, 2017, Scientific Reports.

LAT regulates γδ T cell homeostasis and differentiation

L. Xerri, B. Chetaille, B. Malissen, 2003, Nature Immunology.

Regulatory T Cells + to the Action of Foxp 3 of TCR-MHC Engagement and Is Insensitive Mutant Mice Unfolds Independently Y 136 F Lat Th 2 Lymphoproliferative Disorder of

P. Perrin, M. Mingueneau, Stéphane Chevrier, 2008 .

Deletion of the LIME adaptor protein minimally affects T and B cell development and function

B. Malissen, B. Schraven, M. Malissen, 2007, European journal of immunology.

Distinct mechanisms of peripheral tolerance in transgenic mice.

G. Schönrich, B. Malissen, F. Momburg, 1991, Research in immunology.

Natural Killer Defective Maturation Is Associated with Adverse Clinical Outcome in Patients with Acute Myeloid Leukemia

S. Granjeaud, D. Olive, A. Toubert, 2017, Front. Immunol..

Visualization of the earliest steps of γδ T cell development in the adult thymus

B. Malissen, A. Kissenpfennig, I. Prinz, 2006, Nature Immunology.

Transformation of murine LMTK- cells with purified HLA class I genes. I. Modification of conformation of murine beta 2-microglobulin upon its association with HLA heavy chains.

F. Lemonnier, B. Malissen, P. Golstein, 1983, Journal of immunology.

Influence of antigen density on degree of clonal deletion in T cell receptor transgenic mice.

G. Schönrich, B. Malissen, G. Hämmerling, 1992, International immunology.

Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics

K. Kersse, B. Malissen, O. Burlet-Schiltz, 2019, Nature Immunology.

In Utero Administration of Drugs Targeting Microglia Improves the Neurodevelopmental Outcome Following Cytomegalovirus Infection of the Rat Fetal Brain

F. Michel, P. Gressens, S. Bauer, 2018, Front. Cell. Neurosci..

Cytomegalovirus Infection of the Rat Developing Brain In Utero Prominently Targets Immune Cells and Promotes Early Microglial Activation

P. Gressens, S. Bauer, F. Watrin, 2016, PloS one.

Nucleotide sequence of a light chain gene of the mouse I-A subregion: A beta d.

L. Hood, T. Hunkapiller, M. Malissen, 1983, Science.

The T cell CD6 receptor operates a multitask signalosome with opposite functions in T cell activation

B. Malissen, O. Burlet-Schiltz, M. Malissen, 2020, The Journal of experimental medicine.

Co‐recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR‐induced ubiquitylation

B. Malissen, O. Burlet-Schiltz, Antonio García-Blesa, 2016, Molecular systems biology.

Integrative biology of T cell activation

B. Malissen, M. Malissen, C. Grégoire, 2014, Nature Immunology.

Olfactory dysfunction in LATY136F knock-in mice.

B. Malissen, S. Kondo, T. Yoshizaki, 2021, Auris, nasus, larynx.

Mouse model carrying H222P-Lmna mutation develops muscular dystrophy and dilated cardiomyopathy similar to human striated muscle laminopathies.

S. Varnous, T. Arimura, Y. Fromes, 2005, Human molecular genetics.

The proline-rich sequence of CD3ε controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes

Marie Malissen, Romain Roncagalli, Bernard Malissen, 2008, Nature Immunology.

Revisiting the Timing of Action of the PAG Adaptor Using Quantitative Proteomics Analysis of Primary T Cells

Odile Burlet-Schiltz, Marie Malissen, Romain Roncagalli, 2015, The Journal of Immunology.

High-dimensional mass cytometry analysis of NK cell alterations in AML identifies a subgroup with adverse clinical outcome

S. Granjeaud, D. Olive, D. Blaise, 2021, Proceedings of the National Academy of Sciences.

High-dimensional mass cytometry analysis of NK cell alterations in Acute Myeloid Leukemia identifies a subgroup with adverse clinical outcome

S. Granjeaud, D. Olive, D. Blaise, 2020, medRxiv.

Reconstitution of CD3 zeta coupling to calcium mobilization via genetic complementation.

A. Trautmann, B. Malissen, É. Vivier, 1994, The Journal of biological chemistry.

The pronounced lung lesions developing in LATY136F knock-in mice mimic human IgG4-related lung disease

T. Ishizuka, B. Malissen, Masahiko Zuka, 2021, PloS one.

The tight interallelic positional coincidence that distinguishes T‐cell receptor Jα usage does not result from homologous chromosomal pairing during VαJα rearrangement

J. Casanova, A. Nussenzweig, M. Bonneville, 2001 .

Dynamic recruitment of the adaptor protein LAT: LAT exists in two distinct intracellular pools and controls its own recruitment

D. Olive, F. Sánchez‐Madrid, C. Langlet, 2004, Journal of Cell Science.

Crippling of CD3-zeta ITAMs does not impair T cell receptor signaling.

A. Trautmann, B. Malissen, J. Nunès, 1999, Immunity.

When the T cell antigen receptor (TCR) binds an antigen, the immuno receptor tyrosinebased activation motifs (ITAMs) in the TCR associated CD3 chains are phosphorylated by the tyrosine kinase Lck. That allows recruitment and activation of the tyrosine kinase Zap70

H. Lähdesmäki, R. Aebersold, R. Lahesmaa, 2014 .

Erratum: Reply to “Neutrophils are not required for resolution of acute gouty arthritis in mice”

A. Mócsai, G. Schett, M. Herrmann, 2017, Nature Medicine.

Thymus‐specific serine protease regulates positive selection of a subset of CD4+ thymocytes

A. Carrier, B. Malissen, M. Malissen, 2009, European journal of immunology.

Effects of VEGF blockade on the dynamics of the inflammatory landscape in glioblastoma-bearing mice

G. Rougon, M. Malissen, S. Brustlein, 2019, Journal of Neuroinflammation.

Each of the two productive T cell receptor alpha-gene rearrangements found in both the A10 and BM 3.3 T cell clones give rise to an alpha chain which can contribute to the constitution of a surface-expressed alpha beta dimer.

B. Malissen, M. Malissen, M. Buferne, 1991, International immunology.

A novel type of aberrant T cell receptor alpha-chain gene rearrangement. Implications for allelic exclusion and the V-J recombination process.

B. Malissen, I. Hue, M. Malissen, 1990, Journal of immunology.

Atp6ap2 ablation in adult mice impairs viability through multiple organ deficiencies

Y. Hérault, T. Sorg, M. Champy, 2017, Scientific Reports.

Mapping the SLP76 interactome in T cells lacking each of the GRB2-family adaptors reveals molecular plasticity of the TCR signaling pathway

B. Malissen, S. Audebert, L. Camoin, 2023, Frontiers in Immunology.

Expression and Characterization of Leucocyte Antigens

P. Gregersen, K. Lennert, B. Dörken, 1984 .

T cell activation and thymic tolerance induction require different adhesion intensities of the CD8 co-receptor.

G. Schönrich, B. Malissen, J. Schenkel, 1992, International immunology.

LymphoAtlas: a dynamic and integrated phosphoproteomic resource of TCR signaling in primary T cells reveals ITSN2 as a regulator of effector functions

Miguel Ángel Martínez, J. Garin, B. Malissen, 2020, Molecular systems biology.

Use of TCR ADV gene segments by the δ chain is independent of their position and of CD3 expression

S. Candéias, M. Malissen, P. Marche, 1998 .

Chromosomal localization of two mouse genes encoding thymus-specific serine peptidase and thymus-expressed acidic protein

M. Mattei, A. Carrier, B. Malissen, 2000, Immunogenetics.

Evaluating the efficiency of isotope transmission for improved panel design and a comparison of the detection sensitivities of mass cytometer instruments

Sabine Tricot, Mickael Meyrand, Chiara Sammicheli, 2015, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

Lacrimal Gland and Orbital Lesions in LatY136F Knock-in Mice, a Model for Human IgG4-Related Ophthalmic Disease

B. Malissen, M. Kawano, M. Malissen, 2022, Current eye research.

Neutrophils enhance early Trypanosoma brucei infection onset

P. De Baetselier, M. Mazzone, S. Magez, 2018, Scientific Reports.

Defective LAT signalosome pathology in mice mimics human IgG4-related disease at single-cell level

B. Malissen, M. Malissen, Yinming Liang, 2023, The Journal of experimental medicine.

A T cell clone expresses two T cell receptor alpha genes but uses one alpha beta heterodimer for allorecognition and self MHC-restricted antigen recognition.

L. Hood, B. Malissen, M. Malissen, 1988, Cell.

Evaluating the efficiency of isotope transmission for improved panel design and a comparison of the detection sensitivities of mass cytometer instruments

S. Bertholet, S. Nuti, H. Luche, 2015, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

Involving Th1 and CD8 Effector T Cells Mice into a Lymphoproliferative Disorder Y136F Lat Inflammatory Pathology Afflicting STAT6 Deletion Converts the Th2

E. Devilard, G. Delsol, M. Malissen, 2009 .

The Common Cytokine Receptor ␥ Chain Controls Survival of ␥ / ␦ T Cells

B. Malissen, M. Malissen, J. Disanto, 1997 .

The Single Positive T Cells Found in Cd3-␨ / ␩ Ϫ / Ϫ Mice Overtly React with Self–major Histocompatibility Complex Molecules upon Restoration of Normal Surface Density of T Cell Receptor–cd3 Complex

B. Malissen, M. Malissen, L. Ardouin, 1997 .

The three members of the Vav family proteins form complexes that concur to foam cell formation and atherosclerosis[S]

T. Lawrence, B. Malissen, M. Malissen, 2019, Journal of Lipid Research.

In the absence of its cytosolic domain, the CD28 molecule still contributes to T cell activation

D. Olive, J. Mege, J. Nunès, 2015, Cellular and Molecular Life Sciences.

Th2 lymphoproliferative disorders resulting from defective LAT signalosomes.

M. Mingueneau, B. Malissen, M. Malissen, 2007, Novartis Foundation symposium.