Valerie Schmieder

发表

Genetic engineering approaches to improve posttranslational modification of biopharmaceuticals in different production platforms

M. Andersen, N. Borth, T. Amann, 2019, Biotechnology and bioengineering.

CRISPR/Cas9-Mediated Knockout of MicroRNA-744 Improves Antibody Titer of CHO Production Cell Lines.

Vaibhav Jadhav, N. Borth, Simon Fischer, 2019, Biotechnology journal.

Enhanced targeted DNA methylation with dCas9-DNMT3A3L of the CMV and endogenous promoters entails distinct subsequent histone modification changes in CHO cells.

Heena Dhiman, N. Borth, Valerie Schmieder, 2021, Metabolic engineering.

The contributions of individual galactosyltransferases to protein specific N-glycan processing in Chinese Hamster Ovary cells.

N. Borth, D. Maresch, Valerie Schmieder, 2018, Journal of biotechnology.

Enhanced Genome Editing Tools For Multi-Gene Deletion Knock-Out Approaches Using Paired CRISPR sgRNAs in CHO Cells.

Vaibhav Jadhav, N. Borth, Valerie Schmieder, 2018, Biotechnology journal.

Loss of a newly discovered microRNA in Chinese hamster ovary cells leads to upregulation of N‐glycolylneuraminic acid sialylation on monoclonal antibodies

P. Schulz, Harald Bradl, T. Hartsch, 2021, Biotechnology and bioengineering.

Novel promoters derived from Chinese Hamster Ovary cells via in silico and in vitro analysis.

Heena Dhiman, Inmaculada Hernández, N. Borth, 2019, Biotechnology journal.

A pooled CRISPR/AsCpf1 screen using paired gRNAs to induce genomic deletions in Chinese hamster ovary cells

Heena Dhiman, N. Borth, Valerie Schmieder, 2021, Biotechnology reports.

Towards Maximum Acceleration of Monoclonal Antibody Development: Leveraging Transposase-Mediated Cell Line Generation to Enable GMP Manufacturing within 3 Months using a Stable Pool.

P. Schulz, Simon Fischer, Valerie Schmieder, 2022, Journal of biotechnology.

Biotechnology and Bioengineering

N. Borth, Valerie Schmieder, Helene Faustrup Kildegaard, 2019 .