D. Flood

发表

Hindlimb motor neurons require Cu/Zn superoxide dismutase for maintenance of neuromuscular junctions.

J. A. Gruner, D. Flood, A. Reaume, 1999, The American journal of pathology.

Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease

J. Troncoso, M. West, P. Coleman, 1994, The Lancet.

Neuron numbers and sizes in aging brain: Comparisons of human, monkey, and rodent data

Paul D. Coleman, P. Coleman, D. Flood, 1988, Neurobiology of Aging.

[F-18]FDDNP microPET imaging correlates with brain Aβ burden in a transgenic rat model of Alzheimer disease: Effects of aging, in vivo blockade, and anti-Aβ antibody treatment

Sung-Cheng Huang, Gary W. Small, Vladimir Kepe, 2011, Neurobiology of Disease.

Therapeutic Potential of α7 Nicotinic Acetylcholine Receptors

D. Bertrand, D. Donnelly-roberts, Chih-Hung Lee, 2015, Pharmacological Reviews.

Paul D. Coleman, P. Coleman, S. J. Buell, 1985, Brain Research.

Studies on the Morphological Basis of Orientation Selectivity

P. Coleman, D. Flood, 1995 .

The novel α7 nicotinic acetylcholine receptor agonist EVP-6124 enhances dopamine, acetylcholine, and glutamate efflux in rat cortex and nucleus accumbens

H. Meltzer, D. Hilt, D. Flood, 2014, Psychopharmacology.

Spatial sampling by dendritic trees in visual cortex

R. C. Emerson, P. Coleman, M. C. Whitehead, 1981, Brain Research.

Stability of numbers but not size of mouse forebrain cholinergic neurons to 53 months

P. Coleman, S. J. Buell, D. Flood, 1985, Neurobiology of Aging.

Cu/Zn SOD deficiency potentiates hearing loss and cochlear pathology in aged 129,CD‐1 mice

R. Burkard, R. Salvi, D. Ding, 1999, The Journal of comparative neurology.

Neuropharmacokinetics of two investigational compounds in rats: divergent temporal profiles in the brain and cerebrospinal fluid.

Xing Chen, D. Flood, D. Welty, 2014, Biochemical pharmacology.

Dendritic proliferation in the aging brain as a compensatory repair mechanism.

P. Coleman, D. Flood, Paul D. Coleman, 1986, Progress in brain research.

CEP-11004, an inhibitor of the SAPK/JNK pathway, reduces TNF-alpha release from lipopolysaccharide-treated cells and mice.

D. Bozyczko‐Coyne, M. Leist, D. Flood, 2005, European journal of pharmacology.

Presenilin P264L knock-in mutation: Differential effects on abproduction, amyloid deposition, and neuronal vulnerability

D. Flood, A. Reaume, R. Scott, 2000, Neurobiology of Aging.

Presenilin-1 P264L Knock-In Mutation: Differential Effects on Aβ Production, Amyloid Deposition, and Neuronal Vulnerability

D. Flood, A. Reaume, R. Scott, 2000, The Journal of Neuroscience.

Neuron numbers and dendritic extent in normal aging and Alzheimer's disease

Paul D. Coleman, P. Coleman, D. Flood, 1987, Neurobiology of Aging.

CEP-26401 (Irdabisant), a Potent and Selective Histamine H3 Receptor Antagonist/Inverse Agonist with Cognition-Enhancing and Wake-Promoting Activities

D. Bozyczko‐Coyne, E. Duzic, M. Williams, 2012, Journal of Pharmacology and Experimental Therapeutics.

Variables affecting prepulse inhibition of the startle reflex and the response to antipsychotics in DBA/2NCrl mice

D. Flood, M. Gasior, M. Marino, 2007, Psychopharmacology.

Immunolocalization of the mitogen‐activated protein kinases p42MAPK and JNK1, and their regulatory kinases MEK1 and MEK4, in adult rat central nervous system

P. Contreras, C. Dionne, K. Walton, 1998, The Journal of comparative neurology.

Demonstration of orientation columns with [14C]2-deoxyglucose in a cat reared in a striped environment

P. Coleman, D. Flood, 1979, Brain Research.

Characterization of Pharmacological and Wake-Promoting Properties of the Dopaminergic Stimulant Sydnocarb in Rats

D. Flood, M. Gasior, J. Mathiasen, 2011, Journal of Pharmacology and Experimental Therapeutics.

Quantitative measures of hair cell loss in CBA and C57BL/6 mice throughout their life spans.

R J Salvi, R. Frisina, R. Salvi, 1997, The Journal of the Acoustical Society of America.

Developing predictive CSF biomarkers-a challenge critical to success in Alzheimer's disease and neuropsychiatric translational medicine.

G. Marek, D. Flood, Michael Williams, 2011, Biochemical pharmacology.

AMPA receptor downscaling at the onset of Alzheimer's disease pathology in double knockin mice.

Eric H. Chang, C. Aoki, T. Shirao, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Neuronal plasticity in normal aging and deficient plasticity in Alzheimer's disease: a proposed intercellular signal cascade.

P. Coleman, D. Flood, K. Rogers, 1990, Progress in brain research.

Selective damage to large cells in the cat retinogeniculate pathway by 2,5-hexanedione

W. Merigan, T. Pasternak, D. Flood, 1985, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Glycine transporter (GlyT1) inhibitors with reduced residence time increase prepulse inhibition without inducing hyperlocomotion in DBA/2 mice.

Karla K Kopec, J. Salvino, D. Flood, 2010, Biochemical pharmacology.

FAD mutant PS-1 gene-targeted mice: increased Aβ42 and Aβ deposition without APP overproduction

B. Strooper, W. Annaert, D. Flood, 2002, Neurobiology of Aging.

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

M. Beal, R. Ferrante, N. Kowall, 1996, Nature Genetics.

Critical issues in the analysis of dendritic extent in aging humans, primates, and rodents

D. Flood, 1993, Neurobiology of Aging.

Region-specific stability of dendritic extent in normal human aging and regression in Alzheimer's disease. I. CA1 of hippocampus

D. Flood, S. Hanks, 1991, Brain Research.

Stability of dendrites in cortical barrels of C57BL/6N mice between 4 and 45 months

C. Curcio, P. Coleman, S. J. Buell, 1986, Neurobiology of Aging.

Synaptic loss in the central nucleus of the inferior colliculus correlates with sensorineural hearing loss in the C57BL/6 mouse model of presbycusis

J. Walton, R. Salvi, D. Flood, 1995, Hearing Research.

α7-nAChR agonist enhances neural plasticity in the hippocampus via a GABAergic circuit.

L. Leventhal, D. Flood, H. Patzke, 2016, Journal of neurophysiology.

Increased Expression of IL-1β Converting Enzyme in Hippocampus after Ischemia: Selective Localization in Microglia

P. Contreras, P. Dobrzanski, R. Dirocco, 1996, The Journal of Neuroscience.

Endoplasmic Reticulum Stress-induced Cysteine Protease Activation in Cortical Neurons

R. Neumar, D. Flood, R. Siman, 2001, The Journal of Biological Chemistry.

Activation of c-Jun N-Terminal Kinase and p38 in an Alzheimer's Disease Model Is Associated with Amyloid Deposition

D. Flood, R. Scott, M. Savage, 2002, The Journal of Neuroscience.

Mood stabilizers increase prepulse inhibition in DBA/2NCrl mice

D. Flood, M. Gasior, M. Marino, 2009, Psychopharmacology.

Profiling of endogenous peptides as a tool for studying development and neurological disease.

D. Flood, T. Wengenack, J. Slemmon, 1997, Biopolymers.

Modulation of Secreted β-Amyloid Precursor Protein and Amyloid β-Peptide in Brain by Cholesterol*

B. Greenberg, D. Flood, A. Reaume, 1998, The Journal of Biological Chemistry.

Comparative analysis of cortical gene expression in mouse models of Alzheimer's disease

D. Bozyczko‐Coyne, D. Flood, M. Savage, 2006, Neurobiology of Aging.

Dendritic regression dissociated from neuronal death but associated with partial deafferentation in aging rat supraoptic nucleus

P. Coleman, D. Flood, 1993, Neurobiology of Aging.

A transgenic rat model of Alzheimer's disease with extracellular Aβ deposition

D. Flood, J. Hirsch, R. Scott, 2009, Neurobiology of Aging.

Hippocampal plasticity in normal aging and decreased plasticity in Alzheimer's disease.

P. Coleman, D. Flood, Paul D. Coleman, 1990, Progress in brain research.

The novel α7 nicotinic acetylcholine receptor agonist EVP-6124 enhances dopamine, acetylcholine, and glutamate efflux in rat cortex and nucleus accumbens

H. Meltzer, D. Hilt, D. Flood, 2014, Psychopharmacology.

Caspase inhibition therapy abolishes brain trauma-induced increases in Aβ peptide: Implications for clinical outcome

S. DeKosky, R. Clark, M. Ikonomovic, 2006, Experimental Neurology.

EVP-6124, a novel and selective α7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors

D. Bertrand, D. Hilt, J. Prickaerts, 2012, Neuropharmacology.

Dendritic changes in Alzheimer's disease and factors that may underlie these changes

Peter Davies, Linda Callahan, Gregory A. Jicha, 1998, Progress in Neurobiology.

Profiling of endogenous brain peptides and small proteins: Methodology, computer-assisted analysis, and application to aging and lesion models

D. Flood, J. Slemmon, 1992, Neurobiology of Aging.

in Brain by Cholesterol -Peptide β Precursor Protein and Amyloid -Amyloid β Modulation of Secreted CELL BIOLOGY AND METABOLISM:

B. Greenberg, J. Savage, D. Flood, 2013 .

Region-specific stability of dendritic extent in normal human aging and regression in Alzheimer's disease. II. Subiculum

D. Flood, 1991, Brain Research.

Dendritic extent in human CA2–3 hippocampal pyramidal neurons in normal aging and senile dementia

P. Coleman, D. Flood, M. Guarnaccia, 1987, Brain Research.

Dendritic extent in human dentate gyrus granule cells in normal aging and senile dementia

P. Coleman, S. J. Buell, D. Flood, 1987, Brain Research.

Estimating the number of granule cells in the dentate gyrus with the disector

Paul D. Coleman, Mark J. West, M. West, 1988, Brain Research.

Volumes of the components of the hippocampus in the aging F344 rat

M. West, P. Coleman, D. Flood, 1987, The Journal of comparative neurology.

Concentration-response relationship of the α7 nicotinic acetylcholine receptor agonist FRM-17874 across multiple in vitro and in vivo assays.

D. Bertrand, R. Hurst, M. Hajós, 2015, Biochemical pharmacology.

Continuous infusion of the α7 nicotinic acetylcholine receptor agonist EVP-6124 produces no signs of tolerance at memory-enhancing doses in rats: a pharmacokinetic and behavioral study.

J. Prickaerts, D. Flood, D. Welty, 2015, Behavioural pharmacology.

FAD mutant PS-1 gene-targeted mice: increased A beta 42 and A beta deposition without APP overproduction.

B. de Strooper, W. Annaert, D. Flood, 2002, Neurobiology of aging.

Is Dendritic Proliferation of Surviving Neurons a Compensatory Response to Loss of Neighbors in the Aging Brain

P. Coleman, D. Flood, 1988 .

Targeted Deletion of the Cytosolic Cu/Zn-Superoxide Dismutase Gene (Sod1) Increases Susceptibility to Noise-Induced Hearing Loss

James S. Wright, Richard J. Salvi, R. Salvi, 1999, Audiology and Neurotology.

Thoughts on no neocortical neuronal loss but loss of volume in AD

D. Flood, 1994, Neurobiology of Aging.

Mice lacking cytosolic copper/zinc superoxide dismutase display a distinctive motor axonopathy

J. Shefner, D. Flood, A. Reaume, 1999, Neurology.

Prepulse inhibition of the startle reflex and response to antipsychotic treatments in two outbred mouse strains in comparison to the inbred DBA/2 mouse

D. Flood, M. Gasior, M. Marino, 2011, Psychopharmacology.

Modulation of γ-secretase by EVP-0015962 reduces amyloid deposition and behavioral deficits in Tg2576 mice

B. de Strooper, H. Zetterberg, L. Leventhal, 2012, Molecular Neurodegeneration.

R. Salvi, D. Ding, D. Flood, 1999, Neurobiology of Aging.

The neuropil and GAP-43/B-50 in normally aging and Alzheimer's disease human brain.

P. Coleman, D. Flood, K. Rogers, 1991, Progress in brain research.

Failed Compensatory Dendritic Growth as a Pathophysiological Process in Alzheimer's Disease

P. Coleman, D. Flood, D G Flood, 1986, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

Net dendritic stability of layer II pyramidal neurons in F344 rat entorhinal cortex from 12 to 37 months

P. Coleman, D. Flood, 1991, Neurobiology of Aging.

Species difference in circadian [14C]2-deoxyglucose uptake by suprachiasmatic nuclei

D. Flood, F. P. Gibbs, 1982, Brain Research.

A Golgi study of hypothalamic transplants in young and old host rats

P. Coleman, D. Flood, D. Gash, 1985, Neurobiology of Aging.

Armodafinil promotes wakefulness and activates Fos in rat brain

D. Flood, L. Aimone, John A. Gruner, 2009, Pharmacology Biochemistry and Behavior.

GSM treatment after the onset of Aβ deposition in mice reduces total Aβ load

L. Leventhal, D. Flood, H. Patzke, 2012, Alzheimer's & Dementia.

In vivo [F-18]FDDNP microPET imaging of brain B-amyloid in a transgenic rat model of Alzheimer’s disease

G. Small, V. Kepe, J. Barrio, 2005, Alzheimer's & Dementia.

Therapeutic Potential of α7 Nicotinic Acetylcholine Receptors

D. Bertrand, Chih-Hung Lee, D. Flood, 2015, Pharmacological Reviews.

EVP-6124, a novel and selective α7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors

D. Bertrand, D. Hilt, J. Prickaerts, 2012, Neuropharmacology.

Developing predictive CSF biomarkers-a challenge critical to success in Alzheimer's disease and neuropsychiatric translational medicine.

G. Marek, D. Flood, Michael Williams, 2011, Biochemical pharmacology.

The role of area centralis in the spatial vision of the cat

W. Merigan, T. Pasternak, D. Zehl, 1983, Vision Research.

Hair Cell Loss and Synaptic Loss in Inferior Colliculus of C57BL/6 MICE

R. Frisina, J. Walton, R. Salvi, 1997 .