J. Krause

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In vivo biosynthesis of hypothalamic luteinizing hormone releasing hormone in individual free-running female rats.

J. Krause, J. Advis, J. McKelvy, 1982, Endocrinology.

Molecular basis for the species selectivity of the substance P antagonist CP-96,345.

J. Lowe, J. Krause, B. Sachais, 1993, The Journal of biological chemistry.

Differential expression of insulin-like growth factor genes in rat central nervous system.

J. Milbrandt, S. Burgess, P. Rotwein, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Functional Wild‐Type and Carboxy‐Terminal‐Tagged Rat Substance P Receptors Expressed in Baculovirus‐Infected Insect Sf9 Cells

J. Lyons, M. Innis, J. Krause, 1995, Journal of neurochemistry.

Molecular characterization of a functional cDNA encoding the rat substance P receptor.

A. D. Hershey, J. Krause, James E. Krause, 1990, Science.

Pyrido[2,3-b]pyrazines, discovery of TRPV1 antagonists with reduced potential for the formation of reactive metabolites.

S. Boyce, J. Krause, Xiaozhang Zheng, 2010, Bioorganic & medicinal chemistry letters.

Identification of Methionine as the Site of Covalent Attachment of a p-Benzoyl-Phenylalanine-containing Analogue of Substance P on the Substance P (NK-1) Receptor*

S. Leeman, C. Costello, J. Krause, 1996, The Journal of Biological Chemistry.

Identification of the Site in the Substance P (NK-1) Receptor for Modulation of Peptide Binding by Sulfhydryl Reagents (*)

H. Li, S. Leeman, J. Krause, 1996, The Journal of Biological Chemistry.

Leukocyte effects of C5a-receptor blockade during simulated extracorporeal circulation.

B. Smith, J. Krause, R. Brodbeck, 2007, The Annals of thoracic surgery.

Neuropeptide Y1 subtype pharmacology of a recombinantly expressed neuropeptide receptor.

P. Seeburg, R. Sprengel, J. Krause, 1992, Molecular pharmacology.

The formalin-induced expression of tachykinin peptide and neurokinin receptor messenger RNAs in rat sensory ganglia and spinal cord is modulated by opiate preadministration

J. Krause, K. McCarson, K. Mccarson, 1995, Neuroscience.

Intraspinal substance p-containing projections to the sympathetic preganglionic neuropil in pigeon, Columba livia: High-performance liquid chromatography, radioimmunoassay and electron microscopic evidence

B. Davis, J. Krause, N. Bogan, 1988, Neuroscience.

Measurement of the degradation of luteinizing hormone releasing hormone by hypothalamic tissue.

J. Krause, J. McKelvy, 1983, Methods in enzymology.

Substance P and related peptides : cellular and molecular physiology

Worcester, L. Iversen, S. Nakanishi, 1991 .

The adaptation of enkephalin, tachykinin and monoamine neurons of the basal ganglia following neonatal dopaminergic denervation is dependent on the extent of dopamine depletion

J. Krause, S. Sivam, 1990, Brain Research.

Expression of substance P/neurokinin A-encoding preprotachykinin messenger ribonucleic acids in the rat enteric nervous system.

G. Frantz, C. Sternini, N. Brecha, 1989, Gastroenterology.

Structure, functions, and mechanisms of substance P receptor action.

A. D. Hershey, J. Krause, Y. Takeda, 1992, The Journal of investigative dermatology.

C5a, But Not C3a, Increases VEGF Secretion in ARPE-19 Human Retinal Pigment Epithelial Cells

J. Krause, B. Chenard, R. Meade, 2009, Current eye research.

Nerve growth factor induces mechanical allodynia associated with novel A fibre-evoked spinal reflex activity and enhanced neurokinin-1 receptor activation in the rat

L. Urbán, J. Krause, A. Dray, 1995, Pain.

A human calcium-activated potassium channel gene expressed in vascular smooth muscle.

L. Salkoff, M. Saito, C. Lingle, 1995, The American journal of physiology.

Identification and Characterization of NDT 9513727 [N,N-bis(1,3-Benzodioxol-5-ylmethyl)-1-butyl-2,4-diphenyl-1H-imidazole-5-methanamine], a Novel, Orally Bioavailable C5a Receptor Inverse Agonist

J. Krause, M. E. Buck, R. Brodbeck, 2008, Journal of Pharmacology and Experimental Therapeutics.

Presence of nuclear androgen receptor-like immunoreactivity in neurokinin B-containing neurons of the hypothalamic arcuate nucleus of the adult male rat

G. Prins, J. Krause, P. Ciofi, 1994, Neuroscience Letters.

Dopamine‐Dependent Postnatal Development of Enkephalin and Tachykinin Neurons of Rat Basal Ganglia

G. Breese, J. Krause, J.-S. Hong, 1991, Journal of neurochemistry.

Developmental expression of neurokinin A and functional neurokinin-2 receptors in lung.

R. Osathanondh, K. Haley, C. Lilly, 2001, American journal of physiology. Lung cellular and molecular physiology.

Molecular Biology of Receptors

J. Krause, P. Blount, B. Sachais, 1994 .

Neurokinin-3 receptor distribution in rat and human brain: an immunohistochemical study

J. Lorens, J. Krause, S. Lorens, 1999, Neuroscience.

A substance P (neurokinin-1) receptor mutant carboxyl-terminally truncated to resemble a naturally occurring receptor isoform displays enhanced responsiveness and resistance to desensitization.

G. Hauser, J. Blusztajn, H. Li, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Effect of hyperoxia on substance P expression and airway reactivity in the developing lung.

F. Agani, P. Ernsberger, C. Chang, 1997, The American journal of physiology.

The Discovery of Small Molecule C5a Antagonists

J. Krause, A. Hutchison, 2004 .

G-Protein Coupled Receptor Inverse Agonists: Identification, Pharmacological Relevance and Functional Assays

J. Krause, R. Brodbeck, B. Chenard, 2005 .

Substance P and its receptor neurokinin 1 expression in asthmatic airways.

R. Martin, M. Kraft, H. Chu, 2000, The Journal of allergy and clinical immunology.

Substance P and neurokinin-1 receptor expression by intrinsic airway neurons in the rat.

S. Shapiro, B. Mora, J. Krause, 2000, American journal of physiology. Lung cellular and molecular physiology.

Alterations in neurokinin 1 receptor gene expression in models of pain and inflammation.

J. Krause, K. McCarson, D. Dimaggio, 1995, Canadian journal of physiology and pharmacology.

Mechanisms of desensitization and resensitization of G protein-coupled neurokinin1 and neurokinin2 receptors.

N. Bunnett, J. Krause, E. Grady, 1996, Molecular pharmacology.

In vitro and in vivo pharmacology of S 16474, a novel dual tachykinin NK1 and NK2 receptor antagonist.

J. Fauchère, J. Krause, J. Prost, 1995, European journal of pharmacology.

Substance-P is present in a subset of thyrotrophs in the human pituitary.

K. Roth, J. Krause, 1990, The Journal of clinical endocrinology and metabolism.

Characterization of Substance P‐Like Immunoreactivity and Tachykinin‐Encoding mRNAs in Rat Medullary Thyroid Carcinoma Cell Lines

J. Krause, J. Farah, J. Michel, 1992, Journal of neurochemistry.

The distribution of neurokinin-1 and neurokinin-2 receptors in human central airways.

L. Fabbri, J. Krause, F. Braccioni, 2000, American journal of respiratory and critical care medicine.

The neurokinin-1 receptor antagonist LY306,740 blocks nociception-induced increases in dorsal horn neurokinin-1 receptor gene expression.

J. Krause, K. McCarson, 1996, Molecular pharmacology.

Multiple tachykinins are produced and secreted upon post-translational processing of the three substance P precursor proteins, alpha-, beta-, and gamma-preprotachykinin. Expression of the preprotachykinins in AtT-20 cells infected with vaccinia virus recombinants.

C. Rice, J. Krause, M. MacDonald, 1989, The Journal of biological chemistry.

Posttranslational processing of alpha-, beta-, and gamma-preprotachykinins. Cell-free translation and early posttranslational processing events.

J. Krause, M. MacDonald, D. McCourt, 1988, The Journal of biological chemistry.

Transient receptor potential ion channels as targets for the discovery of pain therapeutics.

J. Krause, B. Chenard, D. Cortright, 2005, Current opinion in investigational drugs.

Characterization of N-(Adamantan-1-ylmethyl)-5-[(3R-aminopyrrolidin-1-yl)methyl]-2-chloro-benzamide, a P2X7 Antagonist in Animal Models of Pain and Inflammation

J. Krause, M. E. Buck, Weifeng Yu, 2008, Journal of Pharmacology and Experimental Therapeutics.

Identification and characterization of NDT 9513727, a novel, orally bioavailable C5a receptor inverse agonist

J. Krause, M. E. Buck, R. Brodbeck, 2008 .

The rising sun shines on substance P and related peptides.

J. Krause, K. Watling, 1993, Trends in pharmacological sciences.

The P2X 3 Antagonist P 1 , P 5 -Di[inosine-5 (cid:1) ] Pentaphosphate Binds to the Desensitized State of the Receptor in Rat Dorsal Root Ganglion Neurons

J. Krause, Weifeng Yu, M. Matchett, 2005 .

Residue 78 in the second transmembrane domain of the neurokinin-1 receptor is important in coupling high affinity agonist binding to multiple second messenger responses.

J. Krause, B. Sachais, R. Brodbeck, 1995, Molecular pharmacology.

Tachykinins in Autonomic Control Systems

J. Krause, C. Helke, A. Niederer, 1991 .

Aminopyrazine CB1 receptor inverse agonists.

Mark T. Kershaw, J. Krause, J. Mao, 2008, Bioorganic & medicinal chemistry letters.

Diminished nociceptive response in mice following immunization with neurokinins

A. Cuello, J. Krause, P. Elliott, 1989, Peptides.

The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2.

M. Caron, R. Lefkowitz, J. Blank, 1993, The Journal of biological chemistry.

Lactone Modulation of the γ-Aminobutyric Acid A Receptor: Evidence for a Positive Modulatory Site

J. Ferrendelli, S. Rothman, J. Krause, 1997 .

Lactone modulation of the gamma-aminobutyric acid A receptor: evidence for a positive modulatory site.

J. Ferrendelli, S. Rothman, J. Krause, 1997, Molecular pharmacology.

Oligo-riboprobes

J. Polak, P. Denny, S. Legon, 2004, Histochemistry.

The polyprotein nature of substance P precursors

J. Krause, M. MacDonald, Y. Takeda, 1989, BioEssays : news and reviews in molecular, cellular and developmental biology.

J. Krause, R. Snider, R. Raddatz, 1995, Journal of neurochemistry.

Amyloid-beta peptide, substance P, and bombesin bind to the serpin-enzyme complex receptor.

A. D. Hershey, J. Krause, D. Perlmutter, 1991, The Journal of biological chemistry.

Expression of the gene for preproatriopeptin in the central nervous system of the rat.

D. Standaert, M. Day, P. Needleman, 1988, Brain research.

Subcellular location of hypothalamic progesterone metabolizing enzymes and evidence for distinct NADH- and NADPH-linked 3 alpha-hydroxysteroid oxidoreductase activities.

J. Krause, H. J. Karavolas, 1980, Journal of steroid biochemistry.

Gonadal steroid regulation of substance P (SP) and SP-encoding messenger ribonucleic acids in the rat anterior pituitary and hypothalamus.

R. Harlan, J. Krause, E. Brown, 1990, Endocrinology.

Distribution of galanin-1, -2 and -3 receptor messenger RNAs in central and peripheral rat tissues

J. Krause, S. M. Waters, 1999, Neuroscience.

Cellular localization of substance P‐ and neurokinin A‐encoding preprotachykinin mRna in the female rat brain

R. Harlan, M. M. Garcia, J. Krause, 1989, The Journal of comparative neurology.

gamma-Preprotachykinin-(72-92)-peptide amide: an endogenous preprotachykinin I gene-derived peptide that preferentially binds to neurokinin-2 receptors.

J. Krause, E. Escher, Y. Takeda, 1990, Proceedings of the National Academy of Sciences of the United States of America.

mRNAs encoding muscarinic and substance P receptors in cultured sympathetic neurons are differentially regulated by LIF or CNTF.

D. Spray, J. Kessler, J. Krause, 1994, Developmental biology.

C5L2, a nonsignaling C5A binding protein.

J. Krause, S. Okinaga, C. Gerard, 2003, Biochemistry.

Inflammation-induced upregulation of NK1 receptor mRNA in dorsal horn neurones.

M. Schäfer, E. Weihe, J. Krause, 1993, Neuroreport.

Neurokinin B- and substance P-like immunoreactivity are co-localized in enteric nerves of rat ileum

K. Roth, J. Krause, A. Yunker, 1999, Regulatory Peptides.

Kainic acid induced seizures cause a marked increase in the expression of neurokinin-3 receptor mRNA in the rat cerebellum

G. Sperk, J. Krause, K. McCarson, 1994, Neuroscience Letters.

Solution hybridization-nuclease protection assays for sensitive detection of differentially spliced substance P- and neurokinin A-encoding messenger ribonucleic acids.

M. Carter, J. Krause, M. MacDonald, 1989, Methods in enzymology.

Depolarization regulates adrenal preproenkephalin mRNA.

I. Black, J. Krause, J. McKelvy, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Differential changes in mRNAs encoding for preprotachykinin A and B after kainic acid‐induced seizures in the rat

G. Sperk, C. Humpel, J. Marksteiner, 1991, Synapse.

Effects of spinal lesions on substance P levels in the rat sympathetic preganglionic cell column: Evidence for local spinal regulation

B. Davis, J. Krause, J. McKelvy, 1984, Neuroscience.

Functional nonequivalence of structurally homologous domains of neurokinin-1 and neurokinin-2 type tachykinin receptors.

J. Krause, P. Blount, 1993, The Journal of biological chemistry.

Structure, expression and second messenger-mediated regulation of the human and rat substance P receptors and their genes

K. B. Chou, J. Krause, P. Blount, 1992, Regulatory Peptides.

Biochemistry of peptide-secreting neurons.

J. Krause, J. McKelvy, K. D. Stewart, 1985, Physiological reviews.

Aminoquinazolines as TRPV1 antagonists: modulation of drug-like properties through the exploration of 2-position substitution.

Mark T. Kershaw, J. Chandrasekhar, J. Krause, 2008, Bioorganic & medicinal chemistry letters.

The co-occurrence of a substance P-like peptide and cholecystokinin-8 in a fiber system of turtle cortex

A. Reiner, W. Eldred, J. Krause, 1985, The Journal of neuroscience : the official journal of the Society for Neuroscience.

The distribution of substance P in turtle nervous system: A radioimmunoassay and immunohistochemical study

K. Keyser, W. Eldred, J. Krause, 1984, The Journal of comparative neurology.

Three rat preprotachykinin mRNAs encode the neuropeptides substance P and neurokinin A.

J. Chirgwin, A. D. Hershey, M. Carter, 1987, Proceedings of the National Academy of Sciences of the United States of America.

In vivo biosynthesis and transport of oxytocin, vasopressin, and neurophysins to posterior pituitary and nucleus of the solitary tract

J. Krause, J. McKelvy, J. White, 1984, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Discovery of novel 6,6-heterocycles as transient receptor potential vanilloid (TRPV1) antagonists.

Mark T. Kershaw, S. Boyce, J. Krause, 2010, Journal of medicinal chemistry.

Molecular Characterization of the Gerbil C5a Receptor and Identification of a Transmembrane Domain V Amino Acid That Is Crucial for Small Molecule Antagonist Interaction*

D. Severance, J. Krause, R. Brodbeck, 2005, Journal of Biological Chemistry.

Diversity in mammalian tachykinin peptidergic neurons: multiple peptides, receptors, and regulatory mechanisms 1

P. Mantyh, J. Krause, C. Helke, 1990, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Properties of the hypothalamic 5α-dihydroprogesterone NADH- and NADPH-linked 3α-hydroxysteroid oxidoreductase activities

J. Krause, H. J. Karavolas, 1981 .

Astroglial distribution of neurokinin-2 receptor immunoreactivity in the rat spinal cord

L. Descarries, J. Krause, V. Karpitskiy, 1998, Neuroscience.

Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and human.

P. Blumberg, A. Szallasi, É. Mezey, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Chronic non-peptide neurokinin receptor antagonist treatment alters striatal tachykinin peptide and receptor gene expression in the rat

J. Krause, K. McCarson, S. Mclean, 1998, Neuroscience Letters.

Structure, Expression and Regulation of the Rat Preprotachykinin I Gene

M. Carter, J. Krause, M. MacDonald, 1987 .

On the presence of NK2 receptor subtypes in peripheral and central tissues

R. Zarnegar, S. Guard, J. Krause, 1993, Regulatory Peptides.

Immunocytochemical localization of neurokinin B in the rat spinal dorsal horn and its association with substance P and GABA: An electron microscopic study

A. Ribeiro-da-Silva, J. Krause, Amber L. McLeod, 2000, The Journal of comparative neurology.

Immunoelectron microscopic localization of NK‐3 receptor in the rat spinal cord

L. Descarries, J. Krause, R. Couture, 1997, Neuroreport.

Functional expression of a novel human neurokinin-3 receptor homolog that binds [3H]senktide and [125I-MePhe7]neurokinin B, and is responsive to tachykinin peptide agonists.

J. Krause, V. Karpitskiy, P. T. Staveteig, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Chapter VI Neurokinin receptors in the CNS

A. Ribeiro-da-Silva, J. Krause, A. L. McLeod, 2000 .

Molecular and Genetic Characterization, Functional Expression, and mRNA Expression Patterns of a Rat Substance P Receptor a

R. Miledi, A. D. Hershey, J. Krause, 1991, Annals of the New York Academy of Sciences.

Regional distribution of neuropeptide γ and other tachykinin peptides derived from the substance P gene in the rat

J. Krause, J. Takeda, Y. Takeda, 1990, Regulatory Peptides.

Dialdehyde sesquiterpenes and other terpenoids as vanilloids.

P. Blumberg, T. Bíró, A. Szallasi, 1998, European journal of pharmacology.

Tetrapeptide tachykinin antagonists: synthesis and modulation of the physicochemical and pharmacological properties of a new series of partially cyclic analogs.

J. Fauchère, J. Krause, J. Paladino, 1993, Journal of medicinal chemistry.

Molecular Biological Studies on the Diversity of Chemical Signalling in Tachykinin Peptidergic Neurons a

A. D. Hershey, J. Krause, Y. Takeda, 1990, Annals of the New York Academy of Sciences.

Localization of leptin binding domain in the leptin receptor.

M. Tota, L. V. D. van der Ploeg, J. Krause, 1998, Molecular pharmacology.

A non‐pungent triprenyl phenol of fungal origin, scutigeral, stimulates rat dorsal root ganglion neurons via interaction at vanilloid receptors

P. Blumberg, T. Bíró, A. Szallasi, 1999, British journal of pharmacology.

Substrate Turnover by Transporters Curtails Synaptic Glutamate Transients

K. Isenberg, C. Zorumski, S. Mennerick, 1999, The Journal of Neuroscience.

Pituitary 5 alpha-dihydroprogesterone 3 alpha-hydroxysteroid oxidoreductases. Subcellular location and properties of NADH- and NADPH-linked activities.

J. Krause, H. J. Karavolas, 1980, The Journal of biological chemistry.

The effects of neurotransmitters and other cellular modulators and factors on hypothalamic and anterior pituitary Δ4 -steroid (progesterone) 5α-reductase activity

J. Krause, H. J. Karavolas, J. J. Halls, 1980, Steroids.

The effect of progesterone analogues, naturally occurring steroids, and contraceptive progestins on hypothalamic and anterior pituitary Δ4-steroid (progesterone) 5α-reductase

J. Krause, H. J. Karavolas, 1978, Steroids.

Ovarian regulation of hypothalamic and pituitary progestin-metabolizing enzyme activities.

P. Bertics, J. Krause, H. J. Karavolas, 1981, Endocrinology.

Distribution of neurons expressing neurokinin B in the rat brain: Immunohistochemistry and in situ hybridization

G. Sperk, J. Marksteiner, J. Krause, 1992, The Journal of comparative neurology.

Luteinizing hormone-releasing hormone peptidase activities in discrete hypothalamic regions and anterior pituitary of the rat: apparent regulation during the prepubertal period and first estrous cycle at puberty.

J. Krause, J. Advis, J. McKelvy, 1982, Endocrinology.

Neurokinin A and neurokinin B in the human retina

Johannes Leierer, J. Krause, E. Schmid, 2006, Peptides.

Localization of the Peptide Binding Domain of the NK‐1 Tachykinin Receptor Using Photoreactive Analogues of Substance P

J. Krause, N. Boyd, R. Kage, 1995, Annals of the New York Academy of Sciences.

TRP channels and pain.

J. Krause, Daniel N Cortright, James E Krause, 2007, Biochimica et biophysica acta.

Distinct and interactive effects of d‐amphetamine and haloperidol on levels of neurotensin and its mRNA in subterritories in the dorsal and ventral striatum of the rat

J. Krause, D. Grosu, D. Zahm, 1998, The Journal of comparative neurology.

Temporal dissociation of neurotensin/neuromedin N mRNA expression in topographically separate subsets of rat striatal neurons following administration of haloperidol.

J. Krause, D. Zahm, E. Williams, 1996, Brain research. Molecular brain research.

Discovery of N-(1-ethylpropyl)-[3-methoxy-5-(2-methoxy-4-trifluoromethoxyphenyl)-6-methyl-pyrazin-2-yl]amine 59 (NGD 98-2): an orally active corticotropin releasing factor-1 (CRF-1) receptor antagonist.

Ping Ge, Taeyoung Yoon, Dario Doller, 2011, Journal of medicinal chemistry.

2-Arylpyrimidines: novel CRF-1 receptor antagonists.

J. Kehne, J. Chandrasekhar, D. Hoffman, 2008, Bioorganic & medicinal chemistry letters.

The design, synthesis and structure-activity relationships of 1-aryl-4-aminoalkylisoquinolines: a novel series of CRF-1 receptor antagonists.

Mark T. Kershaw, J. Kehne, J. Chandrasekhar, 2008, Bioorganic & medicinal chemistry letters.

Organization, structure, and expression of the gene encoding the rat substance P receptor.

A. D. Hershey, J. Krause, P. Dykema, 1991, The Journal of biological chemistry.

Chapter 2. Neuropeptide receptor antagonists for CNS disorders

J. Kehne, J. Krause, G. Maynard, 2003 .

Peptide‐like immunoreactivity in anuran optic nerve fibers

H. Karten, R. Kuljiš, J. Krause, 1984, The Journal of comparative neurology.

The distribution and regulation of vanilloid receptor VR1 and VR1 5′ splice variant RNA expression in rat

J. Krause, D. Cortright, J. F. Sanchez, 2001, Neuroscience.

Immunohistochemical localization of the neuropeptide Y Y1 receptor in rat central nervous system

A. Loewy, J. Krause, K. Migita, 2001, Brain Research.

Expression and cellular localization of substance P/neurokinin A and neurokinin B mRNAs in the rat retina

C. Sternini, J. Krause, K. Anderson, 1989, Visual Neuroscience.

Sexually dimorphic distribution of substance P in specific anterior pituitary cell populations.

K. Roth, J. Krause, E. Brown, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Molecular cloning, structural characterization and functional expression of the human substance P receptor.

K. B. Chou, J. Krause, J. Takeda, 1991, Biochemical and biophysical research communications.

Characterization of the site of cleavage of luteinizing hormone-releasing hormone under conditions of measurement in which LHRH degradation undergoes physiologically related change.

J. Krause, J. Advis, J. McKelvy, 1982, Biochemical and biophysical research communications.

Localization of the tachykinin neurokinin B precursor peptide in rat brain by immunocytochemistry and in situ hybridization

R. Harlan, J. Krause, D. Hurley, 1992, Neuroscience.

The peptide binding site of the substance P (NK-1) receptor localized by a photoreactive analogue of substance P: presence of a disulfide bond.

S. Leeman, J. Krause, N. Boyd, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Effects of systemic resiniferatoxin treatment on substance P mRNA in rat dorsal root ganglia and substance P receptor mRNA in the spinal dorsal horn

T. Hökfelt, A. Szallasi, J. Krause, 1999, Brain Research.

Molecular characterization and functional expression of a substance P receptor from the sympathetic ganglion of Rana catesbeiana

M. A. Simmons, J. Krause, V. Karpitskiy, 1997, Neuroscience.

Different neuropeptide Y receptor subtypes in rat and rabbit vas deferens.

J. Krause, H. Doods, 1991, European journal of pharmacology.

Arginine-vasopressin neurons in the rat hypothalamus produce neurokinin B and co-express the tachykinin NK-3 receptor and angiotensin II type 1 receptor.

H. Kawano, J. Krause, V. Karpitskiy, 2001, Archives of histology and cytology.

Antidiuretic action of tachykinin NK-3 receptor in the rat paraventricular nucleus

Yasufumi Shigeyoshi, H. Okamura, Y. Shigeyoshi, 1996, Brain Research.

Desensitization and enhancement of neurotensin/neuromedin N mRNA responses in subsets of rat caudate-putamen neurons following multiple administrations of haloperidol.

J. Krause, D. Zahm, E. Williams, 1998, Brain research. Molecular brain research.

The cloned rat vanilloid receptor VR1 mediates both R-type binding and C-type calcium response in dorsal root ganglion neurons.

P. Blumberg, A. Szallasi, J. Krause, 1999, Molecular pharmacology.

Neonatal and Adult 6‐Hydroxydopamine‐Induced Lesions Differentially Alter Tachykinin and Enkephalin Gene Expression

G. Breese, R. Mueller, J. Krause, 1987, Journal of neurochemistry.

Lithium increases rat striatal beta- and gamma-preprotachykinin messenger RNAs.

J. McGinty, K. Takeuchi, J. Krause, 1989, The Journal of pharmacology and experimental therapeutics.

Both extracellular and transmembrane residues contribute to the species selectivity of the neurokinin-1 receptor antagonist WIN 51708.

J. Krause, B. Sachais, B S Sachais, 1994, Molecular pharmacology.

The roles of the putative third cytoplasmic loop and cytoplasmic carboxyl tail of NK-1 and NK-2 receptors in agonist stimulated second messenger responses in stably transfected CHO cells

J. Krause, P. Blount, 1993, Regulatory Peptides.

Ligand Binding Kinetics of Substance P and Neurokinin A Receptors Stably Expressed in Chinese Hamster Ovary Cells and Evidence for Differential Stimulation of Inositol 1,4,5‐Trisphosphate and Cyclic AMP Second Messenger Responses

A. D. Hershey, J. Krause, P. Blount, 1992, Journal of neurochemistry.

Limbic seizures cause pronounced changes in the expression of neurokinin B in the hippocampus of the rat

G. Sperk, J. Marksteiner, J. Krause, 1992, Neuroscience.

Pharmacological and Molecular Biological Studies on the Diversity of Rat Tachykinin NK‐2 Receptor Subtypes in Rat CNS, Duodenum, Vas Deferens, and Urinary Bladder a

J. Krause, Y. Takeda, 1991, Annals of the New York Academy of Sciences.

Neuropeptide K potently stimulates salivary gland secretion and potentiates substance P-induced salivation.

J. Krause, Y. Takeda, 1989, Proceedings of the National Academy of Sciences of the United States of America.

The tissue distribution and functional characterization of human VR1.

J. Krause, G. White, T. Zou, 2001, Biochemical and biophysical research communications.

Comparative Autoradiographic Distribution of [125I] —Neuropeptide Gamma and [125I]—Neurokinin A Binding Sites in Guinea Pig Brain

R. Quirion, J. Krause, Y. Takeda, 1991, Annals of the New York Academy of Sciences.

gamma-Preprotachykinin-(72-92)-peptide amide potentiates substance P-induced salivation.

J. Krause, Y. Takeda, 1989, European journal of pharmacology.

The neostriatal mosaic: Basis for the changing distribution of neurokinin‐1 receptor immunoreactivity during development

K. Roth, J. Krause, A. A. Ardelt, 1996, The Journal of comparative neurology.

Analysis of Tachykinin Peptide Family Gene Expression Patterns by Combined High-Performance Liquid Chromatography–Radioimmunoassay

J. Krause, J. Takeda, Y. Takeda, 1991 .

Substance P and substance P receptor histochemistry in human neurodegenerative diseases

B. Kosofsky, R. Ferrante, N. Kowall, 1992, Regulatory Peptides.

Human Astrocytoma Cells (U‐87 MG) Exhibit a Specific Substance P Binding Site with the Characteristics of an NK‐1 Receptor

J. Krause, Y. Nakata, Y. Hirai, 1996, Journal of neurochemistry.

Preferential synaptic relationships between substance P-immunoreactive boutons and neurokinin 1 receptor sites in the rat spinal cord.

A. Cuello, A. Ribeiro-da-Silva, J. Krause, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Comparative distribution of neurokinin B-, substance P- and enkephalin-like immunoreactivities and neurokinin B messenger RNA in the basal forebrain of the rat: Evidence for neurochemical compartmentation

J. Marksteiner, J. Krause, A. Saria, 1992, Neuroscience.

Biphasic response of hippocampal dynorphin expression following recurrent limbic seizure

Jeffrey H. D. White, J. Lauterborn, C. Gall, 1992, Molecular and Cellular Neuroscience.

Photoaffinity labeling of mutant neurokinin-1 receptors reveals additional structural features of the substance P/NK-1 receptor complex.

H. Li, S. Leeman, J. Krause, 2001, Biochemistry.

In vivo biosynthesis of [35S]- and [3H]substance P in the striatum of the rat and their axonal transport to the substantia nigra

A. Reiner, J. Krause, J. Advis, 1984, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Resiniferatoxin‐type phorboid vanilloids display capsaicin‐like selectivity at native vanilloid receptors on rat DRG neurons and at the cloned vanilloid receptor VR1

P. Blumberg, T. Bíró, A. Szallasi, 1999, British journal of pharmacology.

In vivo biosynthesis and transport of oxytocin, vasopressin and neurophysin from the hypothalamus to the spinal cord

J. Krause, J. McKelvy, J. White, 1986, Neuroscience.

Luteinizing hormone-releasing hormone peptidase activities in the female rat: characterization by an assay based on high-performance liquid chromatography.

J. Krause, J. Advis, J. McKelvy, 1982, Analytical biochemistry.

Tachykinin Systems in the Spinal Cord and Basal Ganglia: Influence of Neonatal Capsaicin Treatment or Dopaminergic Intervention on Levels of Peptides, Substance P–Encoding mRNAs, and Substance P Receptor mRNA

J. Krause, S. Sivam, James E. Krause, 1992, Journal of neurochemistry.

De novo expression of the neurokinin 1 receptor in spinal lamina I pyramidal neurons in polyarthritis

G. Bennett, A. Ribeiro-da-Silva, J. Krause, 2009, The Journal of comparative neurology.

Immunocytochemical localization of neurokinin B in the rat spinal dorsal horn and its association with substance P and GABA: An electron microscopic study

A. Ribeiro-da-Silva, J. Krause, A. McLeod, 2000, The Journal of comparative neurology.

Hunting for ion channel modulators with herpes simplex virus

J. Krause, M. E. Buck, D. Cortright, 2007, Nature Methods.

Presence and Ontogeny of Enkephalin and Substance P in the Chick Ciliary Ganglion

J. Krause, J. McKelvy, J. White, 1985, Journal of neurochemistry.

De novo expression of the neurokinin 1 receptor in spinal lamina I pyramidal neurons in polyarthritis

G. Bennett, A. Ribeiro-da-Silva, J. Krause, 2009, The Journal of comparative neurology.

Pyrido[2,3-b]pyrazines, discovery of TRPV1 antagonists with reduced potential for the formation of reactive metabolites.

S. Boyce, J. Krause, Xiaozhang Zheng, 2010, Bioorganic & medicinal chemistry letters.