Changyuan Wang

Huijun Sun, Zhihao Liu, J. Qin, 2016, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Molecular mechanisms of biliary excretion of cefditoren and the effects of cefditoren on the expression levels of hepatic transporters.

Huijun Sun, Y. Kato, Q. Meng, 2010, Drug metabolism and pharmacokinetics.

Benzylpenicillin inhibits the renal excretion of acyclovir by OAT1 and OAT3

Huijun Sun, Jinyong Peng, Q. Meng, 2013, Pharmacological reports : PR.

The oligopeptide transporter 2-mediated reabsorption of entecavir in rat kidney.

Huijun Sun, Q. Meng, Changyuan Wang, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Peptide cotransporter 1 in intestine and organic anion transporters in kidney are targets of interaction between JBP485 and lisinopril in rats.

Huijun Sun, Jinyong Peng, Q. Meng, 2012, Drug metabolism and pharmacokinetics.

Inhibitory effect of zinc on the absorption of JBP485 via the gastrointestinal oligopeptide transporter (PEPT1) in rats.

Jinyong Peng, Q. Meng, Changyuan Wang, 2011, Drug metabolism and pharmacokinetics.

Pharmacokinetic Interaction between JBP485 and Cephalexin in Rats

Huijun Sun, Q. Meng, Changyuan Wang, 2010, Drug Metabolism and Disposition.

Structure-based modification of carbonyl-diphenylpyrimidines (Car-DPPYs) as a novel focal adhesion kinase (FAK) inhibitor against various stubborn cancer cells.

Xiaodong Ma, Zhihao Liu, Changyuan Wang, 2019, European journal of medicinal chemistry.

Organic anion transporters 1 (OAT1) and OAT3 meditated the protective effect of rhein on methotrexate-induced nephrotoxicity

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2017 .

Protective effects of formononetin against rhabdomyolysis-induced acute kidney injury by upregulating Nrf2 in vivo and in vitro

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2016 .

Luteolin attenuates glucocorticoid‐induced osteoporosis by regulating ERK/Lrp‐5/GSK‐3β signaling pathway in vivo and in vitro

Huijun Sun, Xiaodong Ma, Yue Jin, 2018, Journal of cellular physiology.

A stronger reversal effect of the combination of dasatinib and menadione on P-gp-mediated multidrug resistance in human leukemia K562/Adr cell line

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2017 .

Activation of PGC‐1α via isoliquiritigenin‐induced downregulation of miR‐138‐5p alleviates nonalcoholic fatty liver disease

Huijun Sun, Q. Meng, Changyuan Wang, 2022, Phytotherapy research : PTR.

Pharmacokinetics of phosphocreatine and its active metabolite creatine in the mouse plasma and myocardium

Huijun Sun, Changyuan Wang, Ke-xin Liu, 2014, Pharmacological reports : PR.

A new ent-labdane diterpenoid lactone from Andrographis paniculata

Zhanping Gou, Changyuan Wang, Ji-hong Yao, 2009 .

Targeting P‐glycoprotein and SORCIN: Dihydromyricetin strengthens anti‐proliferative efficiency of adriamycin via MAPK/ERK and Ca2+‐mediated apoptosis pathways in MCF‐7/ADR and K562/ADR

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2018, Journal of cellular physiology.

α-Lipoic acid protects HAECs from high glucose-induced apoptosis via decreased oxidative stress, ER stress and mitochondrial injury

Huijun Sun, Jinyong Peng, Yue Jin, 2015 .

Novel amino acid-substituted diphenylpyrimidine derivatives as potent BTK inhibitors against B cell lymphoma cell lines.

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Bioorganic & medicinal chemistry.

Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Regulatory toxicology and pharmacology : RTP.

Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells

Huijun Sun, Yue Jin, Zhihao Liu, 2018, Inflammation.

Leucine‑enriched essential amino acids promote muscle protein synthesis and ameliorate exercise-induced exhaustion in prolonged endurance exercise in rats

Changyuan Wang, Kexin Liu, Wenzhong Wu, 2022, Nutrire.

Dioscin alleviates lipopolysaccharide-induced inflammatory kidney injury via the microRNA let-7i/TLR4/MyD88 signaling pathway.

Huijun Sun, Jinyong Peng, Y. Qi, 2016, Pharmacological research.

Yangonin protects against non-alcoholic fatty liver disease through farnesoid X receptor.

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2019, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Effects of calycosin against high‐fat diet‐induced nonalcoholic fatty liver disease in mice

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2018, Journal of gastroenterology and hepatology.

Hepatoprotection of auraptene from the peels of citrus fruits against 17α-ethinylestradiol-induced cholestasis in mice by activating farnesoid X receptor.

Huijun Sun, Xiaodong Ma, Q. Meng, 2019, Food & function.

Yangonin protects against estrogen-induced cholestasis in a farnesoid X receptor-dependent manner.

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2019, European journal of pharmacology.

Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor.

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Food & function.

Yangonin protects against cholestasis and hepatotoxity via activation of farnesoid X receptor in vivo and in vitro

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Toxicology and applied pharmacology.

Alisol B 23-acetate protects against non-alcoholic steatohepatitis in mice via farnesoid X receptor activation

Huijun Sun, Q. Meng, Xiaokui Huo, 2016, Acta Pharmacologica Sinica.

Alisol B 23-acetate protects against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes involved in bile acid homeostasis.

Huijun Sun, Q. Meng, Xiaokui Huo, 2015, Toxicology and applied pharmacology.

Protective effects of alisol B 23-acetate from edible botanical Rhizoma alismatis against carbon tetrachloride-induced hepatotoxicity in mice.

Huijun Sun, Zhihao Liu, Q. Meng, 2015, Food & function.

Protective Effects of Alisol B 23-Acetate Via Farnesoid X Receptor-Mediated Regulation of Transporters and Enzymes in Estrogen-Induced Cholestatic Liver Injury in Mice

Huijun Sun, Zhihao Liu, Q. Meng, 2015, Pharmaceutical Research.

Alisol B 23-acetate promotes liver regeneration in mice after partial hepatectomy via activating farnesoid X receptor.

Huijun Sun, Jinyong Peng, Q. Meng, 2014, Biochemical pharmacology.

Laennec protects murine from concanavalin A-induced liver injury through inhibition of inflammatory reactions and hepatocyte apoptosis.

Huijun Sun, Tao Yang, Changyuan Wang, 2008, Biological & pharmaceutical bulletin.

Cilastatin protects against imipenem-induced nephrotoxicity via inhibition of renal organic anion transporters (OATs)

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2019, Acta pharmaceutica Sinica. B.

Protective effect of JBP485 on concanavalin A‐induced liver injury in mice

Jinyong Peng, Tao Yang, Xiaochi Ma, 2009, The Journal of pharmacy and pharmacology.

Protective effect of JBP485 on concanavalin A-induced hepatocyte toxicity in primary cultured rat hepatocytes.

Huijun Sun, Jinyong Peng, Tao Yang, 2008, European journal of pharmacology.

Changes in expression of renal Oat1, Oat3 and Mrp2 in cisplatin-induced acute renal failure after treatment of JBP485 in rats.

Huijun Sun, Jinyong Peng, Q. Meng, 2012, Toxicology and applied pharmacology.

Soluplus®/TPGS mixed micelles for co-delivery of docetaxel and piperine for combination cancer therapy

Xiaodong Ma, Jianping Wu, Youwei Xu, 2020, Pharmaceutical development and technology.

Design, synthesis, and biological evaluation of cyano-substituted 2,4-diarylaminopyrimidines as potent JAK3 inhibitors for the treatment of B-cell lymphoma.

Xiaodong Ma, Yue Jin, Bin Wu, 2021, Bioorganic chemistry.

JAK3 inhibitors based on thieno[3,2-d]pyrimidine scaffold: design, synthesis and bioactivity evaluation for the treatment of B-cell lymphoma.

Xiaodong Ma, Changyuan Wang, Kexin Liu, 2019, Bioorganic chemistry.

Organic anion transporters also mediate the drug–drug interaction between imipenem and cilastatin

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2018, Asian journal of pharmaceutical sciences.

Isoliquiritigenin-mediated miR-23a-3p inhibition activates PGC-1α to alleviate alcoholic liver injury.

Huijun Sun, Q. Meng, Changyuan Wang, 2021, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Targeting P-glycoprotein expression and cancer cell energy metabolism: combination of metformin and 2-deoxyglucose reverses the multidrug resistance of K562/Dox cells to doxorubicin

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2016, Tumor Biology.

Dioscin restores the activity of the anticancer agent adriamycin in multidrug-resistant human leukemia K562/adriamycin cells by down-regulating MDR1 via a mechanism involving NF-κB signaling inhibition.

Huijun Sun, Jinyong Peng, Q. Meng, 2013, Journal of natural products.

Structural optimization of diphenylpyrimidine scaffold as potent and selective epidermal growth factor receptor inhibitors against L858R/T790M resistance mutation in nonsmall cell lung cancer

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Chemical biology & drug design.

Synthesis and biological activity of imidazole group-substituted arylaminopyrimidines (IAAPs) as potent BTK inhibitors against B-cell lymphoma and AML.

Huijun Sun, Xiaodong Ma, Bin Wu, 2020, Bioorganic chemistry.

Methotrexate-bestatin interaction: involvement of P-glycoprotein and organic anion transporters in rats.

Huijun Sun, Q. Meng, Xiaokui Huo, 2014, International journal of pharmaceutics.

OAT1 and OAT3: targets of drug-drug interaction between entecavir and JBP485.

Huijun Sun, Jinyong Peng, Q. Meng, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Inhibitory effect of JBP485 on renal excretion of acyclovir by the inhibition of OAT1 and OAT3.

Huijun Sun, Jinyong Peng, Q. Meng, 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Activating the PGC-1α/TERT Pathway by Catalpol Ameliorates Atherosclerosis via Modulating ROS Production, DNA Damage, and Telomere Function: Implications on Mitochondria and Telomere Link

Huijun Sun, Yue Jin, Zhihao Liu, 2018, Oxidative medicine and cellular longevity.

Identification of highly potent BTK and JAK3 dual inhibitors with improved activity for the treatment of B-cell lymphoma.

Xiaodong Ma, Zhihao Liu, Q. Meng, 2018, European journal of medicinal chemistry.

Design and synthesis of sulfonamide-substituted diphenylpyrimidines (SFA-DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors with improved activity toward B-cell lymphoblastic leukemia.

Jinyong Peng, Xiaodong Ma, Li-na Xu, 2017, European journal of medicinal chemistry.

Structural optimization of diphenylpyrimidine derivatives (DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors with improved activity toward B leukemia cell lines.

Jinyong Peng, Xiaodong Ma, Zhihao Liu, 2017, European journal of medicinal chemistry.

Anti‐Postmenopausal osteoporosis effects of Isopsoralen: A bioinformatics‐integrated experimental study

Huijun Sun, Yue Jin, Q. Meng, 2022, Phytotherapy research : PTR.

Risk assessment and molecular mechanism study of drug-drug interactions between rivaroxaban and tyrosine kinase inhibitors mediated by CYP2J2/3A4 and BCRP/P-gp

Huijun Sun, Q. Meng, Changyuan Wang, 2022, Frontiers in Pharmacology.

Protective effects of yangonin from an edible botanical Kava against lithocholic acid‐induced cholestasis and hepatotoxicity

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, European journal of pharmacology.

Microbial transformation of acetyl-11-keto-β-boswellic acid and their inhibitory activity on LPS-induced NO production.

Xiaochi Ma, Yan Wang, Bao-jing Zhang, 2013, Bioorganic & medicinal chemistry letters.

Dioscin attenuates renal ischemia/reperfusion injury by inhibiting the TLR4/MyD88 signaling pathway via up-regulation of HSP70.

Huijun Sun, Jinyong Peng, Y. Qi, 2015, Pharmacological research.

CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism

Huijun Sun, Yue Jin, Q. Meng, 2020, Frontiers in Pharmacology.

Scutellarin ameliorates nonalcoholic fatty liver disease through the PPARγ/PGC-1α-Nrf2 pathway

Yufeng Fu, Huijun Sun, Jinyong Peng, 2018, Free radical research.

Resveratrol enhances the protective effects of JBP485 against indomethacin-induced rat intestinal damage in vivo and vitro through up-regulating oligopeptide transporter 1 (Pept1).

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Naringin inhibits TNF-α induced oxidative stress and inflammatory response in HUVECs via Nox4/NF-κ B and PI3K/Akt pathways.

Huijun Sun, Jinyong Peng, Yue Jin, 2014, Current pharmaceutical biotechnology.

Novel Pyrimidines as Multitarget Protein Tyrosine Kinase Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis (IPF)

Bo Sun, Huijun Sun, Xiaodong Ma, 2019, ChemMedChem.

Protective effects of glycyrrhizic acid from edible botanical glycyrrhiza glabra against non-alcoholic steatohepatitis in mice.

Huijun Sun, Zhihao Liu, Q. Meng, 2016, Food & function.

Identifying the Dominant Contribution of Human Cytochrome P450 2J2 to the Metabolism of Rivaroxaban, an Oral Anticoagulant

Huijun Sun, Q. Meng, Changyuan Wang, 2021, Cardiovascular Drugs and Therapy.

Dihydroartemisinin and doxorubicin co-loaded Soluplus®-TPGS mixed micelles: formulation characterization, cellular uptake, and pharmacodynamic studies

Xiaodong Ma, Jing Zhao, Bao-jing Zhang, 2019, Pharmaceutical development and technology.

Soluplus/TPGS mixed micelles for dioscin delivery in cancer therapy

Jinyong Peng, Youwei Xu, Jing Zhao, 2017, Drug development and industrial pharmacy.

Decreased liver distribution of entecavir is related to down-regulation of Oat2/Oct1 and up-regulation of Mrp1/2/3/5 in rat liver fibrosis.

Huijun Sun, Jinyong Peng, Q. Meng, 2015, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Puerarin sensitized K562/ADR cells by inhibiting NF‐κB pathway and inducing autophagy

Huijun Sun, Xiaodong Ma, Q. Meng, 2020, Phytotherapy research : PTR.

Dioscin enhances methotrexate absorption by down-regulating MDR1 in vitro and in vivo.

Huijun Sun, Jinyong Peng, Q. Meng, 2014, Toxicology and applied pharmacology.

Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response.

Huijun Sun, Q. Meng, Changyuan Wang, 2021, International immunopharmacology.

PEPT1 involved in the uptake and transepithelial transport of cefditoren in vivo and in vitro.

Jinyong Peng, Xiaochi Ma, Changyuan Wang, 2009, European journal of pharmacology.

Dioscin promotes osteoblastic proliferation and differentiation via Lrp5 and ER pathway in mouse and human osteoblast-like cell lines

Huijun Sun, Jinyong Peng, Yue Jin, 2014, Journal of Biomedical Science.

Targeting of miR-96-5p by catalpol ameliorates oxidative stress and hepatic steatosis in LDLr-/- mice via p66shc/cytochrome C cascade

Huijun Sun, Xiaodong Ma, Yue Jin, 2020, Aging.

Fenretinide-polyethylene glycol (PEG) conjugate with improved solubility enhanced cytotoxicity to cancer cell and potent in vivo efficacy

Xiaodong Ma, Youwei Xu, Changyuan Wang, 2020, Pharmaceutical development and technology.

Mixed micelles of TPGS and Soluplus® for co-delivery of paclitaxel and fenretinide: in vitro and in vivo anticancer study

Xiaodong Ma, Youwei Xu, Changyuan Wang, 2020, Pharmaceutical development and technology.

Uptake, Transport and Regulation of JBP485 by PEPT1 in vitro and in vivo

Zhihao Liu, Q. Meng, Changyuan Wang, 2011, Peptides.

Inhibitory effect of 1α,25-dihydroxyvitamin D₃ on excretion of JBP485 via organic anion transporters in rats.

Huijun Sun, Jinyong Peng, Q. Meng, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Comparative Inhibitory Effects of Natural Biflavones from Ginkgo against Human CYP1B1 in Recombinant Enzymes and MCF-7 Cells

Hong Yu, Huijun Sun, Q. Meng, 2022, Planta Medica.

Effects of JBP485 on the expression and function of PEPT1 in indomethacin-induced intestinal injury in rats and damage in Caco-2 cells

Q. Meng, Changyuan Wang, Kexin Liu, 2011, Peptides.

Adenine: an important drug scaffold for the design of antiviral agents

Xiaodong Ma, Changyuan Wang, Kexin Liu, 2015, Acta pharmaceutica Sinica. B.

Protective effect of Rhein against vancomycin‐induced nephrotoxicity through regulating renal transporters and Nrf2 pathway

Huijun Sun, Xiaodong Ma, Deshi Dong, 2022, Phytotherapy research : PTR.

Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats

Jinyong Peng, Y. Qi, Li-na Xu, 2016, Nutrients.

WITHDRAWN: Structure optimizations of the novel benzophenone derivatives as potential HIV-1 inhibitors

Xiaodong Ma, Yong-tang Zheng, Changyuan Wang, 2016 .

Identification of the novel N-phenylbenzenesulfonamide derivatives as potent HIV inhibitors

Xiaodong Ma, Yong-tang Zheng, Changyuan Wang, 2015 .

Regio- and stereo-selective oxidation of β-boswellic acids transformed by filamentous fungi

Xiaochi Ma, Xiaokui Huo, Chao Wang, 2015 .

Biotransformation of 11-keto-β-boswellic acid by Cunninghamella blakesleana.

Xiaochi Ma, Xiaokui Huo, Chao Wang, 2013, Phytochemistry.

Biotransformation of imperatorin by Penicillium janthinellum. Anti-osteoporosis activities of its metabolites.

Xiaochi Ma, Changyuan Wang, Kexin Liu, 2013, Food chemistry.

Microbial transformation of deoxyandrographolide and their inhibitory activity on LPS-induced NO production in RAW 264.7 macrophages.

Bao-jing Zhang, Changyuan Wang, Kexin Liu, 2012, Bioorganic & medicinal chemistry letters.

Microbial transformation of deoxyandrographolide by Fusarium graminearum AS 3.4598

Xiaochi Ma, Bao-jing Zhang, Changyuan Wang, 2011, Journal of Asian natural products research.

Bioactive metabolites of Schisanlactone E transformed by Cunninghamella blakesleana AS 3.970.

Xiaochi Ma, Xiaokui Huo, Chao Wang, 2014, Fitoterapia.

Microbial transformation of cinobufotalin by Alternaria alternate AS 3.4578 and Aspergillus niger AS 3.739

Xiaochi Ma, Bao-jing Zhang, Changyuan Wang, 2013 .

Biotransformation of osthole by Mucor spinosus

H. Kuang, Xiaochi Ma, Bao-jing Zhang, 2012 .

Microbial biotransformation of kurarinone by Cunninghamella echinulata AS 3.3400

Qipeng Yuan, Xiaochi Ma, Bao-jing Zhang, 2012, Journal of Asian natural products research.

Simultaneous Determination of Resibufogenin and Its Major Metabolite 3-epi-Resibufogenin in Rat Plasma by HPLC Coupled with Tandem Mass Spectrometry

P. Chang, Xiaochi Ma, Changyuan Wang, 2012, Chromatographia.

Efficient isolation and purification of five products from microbial biotransformation of cinobufagin by high-speed counter-current chromatography.

Xiaochi Ma, Bao-jing Zhang, Changyuan Wang, 2010, Journal of separation science.

Preparative Separation of Four Major Bufadienolides from the Chinese Traditional Medicine, Chansu, Using High-Speed Counter-Current Chromatography

Changyuan Wang, Ji-hong Yao, Li Lv, 2010, Natural product communications.

Microbial transformation of Norkurarinone by Cunninghamella blakesleana AS 3.970

Qipeng Yuan, Xiaochi Ma, Bao-jing Zhang, 2012, Journal of Asian natural products research.

Covalent binding design strategy: A prospective method for discovery of potent targeted anticancer agents.

Xiaodong Ma, Changyuan Wang, Kexin Liu, 2017, European journal of medicinal chemistry.

Protective effect of cilastatin against diclofenac‐induced nephrotoxicity through interaction with diclofenac acyl glucuronide via organic anion transporters

Huijun Sun, Xiaodong Ma, Q. Meng, 2020, British journal of pharmacology.

Targeting renal OATs to develop renal protective agent from traditional Chinese medicines: Protective effect of Apigenin against Imipenem‐induced nephrotoxicity

Huijun Sun, Xiaodong Ma, Q. Meng, 2020, Phytotherapy research : PTR.

Synthesis and biological evaluation of morpholine-substituted diphenylpyrimidine derivatives (Mor-DPPYs) as potent EGFR T790M inhibitors with improved activity toward the gefitinib-resistant non-small cell lung cancers (NSCLC).

Xiaodong Ma, Q. Meng, Changyuan Wang, 2017, European journal of medicinal chemistry.

Development and evaluation of a novel drug delivery: Soluplus®/TPGS mixed micelles loaded with piperine in vitro and in vivo

Jinyong Peng, Youwei Xu, Yingying Ding, 2018, Drug development and industrial pharmacy.

Effects of epigallocatechin gallate on the cell-wall structure of Mycobacterial smegmatis mc2155

Changyuan Wang, Y. Xin, Shizhu Zang, 2015, Natural product research.

RAPID SEPARATION OF FLAVONOIDS FROM HYDROLYSIS PRODUCTS OF Epimedium koreanum

Tongxiang Liu, Xiaochi Ma, Bao-jing Zhang, 2012 .

Characterization of three naturally occurring lignans, sesamol, sesamolin, and sesamin, as potent inhibitors of human cytochrome P450 46A1: Implications for treating excitatory neurotoxicity

Huijun Sun, Q. Meng, Changyuan Wang, 2022, Frontiers in Pharmacology.

Alpha‐Lipoic Acid Promotes Osteoblastic Formation in H2O2‐Treated MC3T3‐E1 Cells and Prevents Bone Loss in Ovariectomized Rats

Huijun Sun, Yue Jin, Q. Meng, 2015, Journal of cellular physiology.

Novel dual small-molecule HIV inhibitors: scaffolds and discovery strategies.

Xiaodong Ma, Changyuan Wang, Kexin Liu, 2014, Current pharmaceutical design.

Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.

Jinyong Peng, Li-na Xu, L. Yin, 2016, Environmental toxicology and pharmacology.

Novel 4-anilinoquinazoline derivatives featuring an 1-adamantyl moiety as potent EGFR inhibitors with enhanced activity against NSCLC cell lines.

Xiaodong Ma, Yue Jin, Xu Han, 2016, European journal of medicinal chemistry.

Dioscin suppresses human laryngeal cancer cells growth via induction of cell-cycle arrest and MAPK-mediated mitochondrial-derived apoptosis and inhibition of tumor invasion.

Jinyong Peng, Y. Qi, Li-na Xu, 2016, European journal of pharmacology.

Challenges and Perspectives on the Development of Small-Molecule EGFR Inhibitors against T790M-Mediated Resistance in Non-Small-Cell Lung Cancer.

Xiaodong Ma, Youwen Zhou, Changyuan Wang, 2016, Journal of medicinal chemistry.

7‐O‐geranylquercetin‐induced autophagy contributes to apoptosis via ROS generation in human non‐small cell lung cancer cells

Xiaodong Ma, Changyuan Wang, Yanyan Jiang, 2017, Life sciences.

Synthesis and biological evaluation of azole-diphenylpyrimidine derivatives (AzDPPYs) as potent T790M mutant form of epidermal growth factor receptor inhibitors.

Jinyong Peng, Xiaodong Ma, Yue Jin, 2016, Bioorganic & medicinal chemistry.

A cost-effective method to prepare curcumin nanosuspensions with enhanced oral bioavailability.

Yanfang Ding, Changyuan Wang, Jing Zhao, 2017, Journal of colloid and interface science.

Catalpol attenuates oxidative stress and promotes autophagy in TNF-α-exposed HAECs by up-regulating AMPK

Huijun Sun, Yue Jin, Zhihao Liu, 2017 .

Inhibitory effect of valsartan on the intestinal absorption and renal excretion of bestatin in rats.

Huijun Sun, Jinyong Peng, Q. Meng, 2014, Journal of pharmaceutical sciences.

Design, synthesis and biological evaluation of sulfonamide-substituted diphenylpyrimidine derivatives (Sul-DPPYs) as potent focal adhesion kinase (FAK) inhibitors with antitumor activity.

Xiaodong Ma, Zhihao Liu, Changyuan Wang, 2017, Bioorganic & medicinal chemistry.

Protective effects of ginsenoside Rg1 against lipopolysaccharide/d‐galactosamine‐induced acute liver injury in mice through inhibiting toll‐like receptor 4 signaling pathway

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, International immunopharmacology.

Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2016, Oncotarget.

Yangonin inhibits ethanol-induced hepatocyte senescence via miR-194/FXR axis.

Huijun Sun, Q. Meng, Changyuan Wang, 2020, European journal of pharmacology.

The osteogenesis-promoting effects of alpha-lipoic acid against glucocorticoid-induced osteoporosis through the NOX4, NF-kappaB, JNK and PI3K/AKT pathways

Huijun Sun, Yue Jin, Q. Meng, 2017, Scientific Reports.

Identification of 2(1H)-pyrimidinones as potential EGFR T790M inhibitors for the treatment of gefitinib-resistant non-small cell lung cancer.

Xiaodong Ma, Changyuan Wang, Guoping Huang, 2019, Bioorganic chemistry.

Luteolin protects HUVECs from TNF-α-induced oxidative stress and inflammation via its effects on the Nox4/ROS-NF-κB and MAPK pathways.

Huijun Sun, Yue Jin, Q. Meng, 2014, Journal of atherosclerosis and thrombosis.

JBP485 attenuates vancomycin-induced nephrotoxicity by regulating the expressions of organic anion transporter (Oat) 1, Oat3, organic cation transporter 2 (Oct2), multidrug resistance-associated protein 2 (Mrp2) and P-glycoprotein (P-gp) in rats.

Huijun Sun, Zhihao Liu, Q. Meng, 2018, Toxicology letters.

7-O-Geranylquercetin induces apoptosis in gastric cancer cells via ROS-MAPK mediated mitochondrial signaling pathway activation.

Changyuan Wang, Y. Zhen, Xiaodong Xu, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells

Huijun Sun, Yue Jin, Zhihao Liu, 2018, Inflammation.

Puerarin improves methotrexate-induced renal damage by up-regulating renal expression of Oat1 and Oat3 in vivo and in vitro.

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Noncovalent EGFR T790M/L858R inhibitors based on diphenylpyrimidine scaffold: Design, synthesis, and bioactivity evaluation for the treatment of NSCLC.

Huijun Sun, Xiaodong Ma, Q. Meng, 2021, European journal of medicinal chemistry.

Design and synthesis of diphenylpyrimidine derivatives (DPPYs) as potential dual EGFR T790M and FAK inhibitors against a diverse range of cancer cell lines.

Xiaodong Ma, Changyuan Wang, Kexin Liu, 2019, Bioorganic chemistry.

Renal transporter OAT1 and PPAR‐α pathway co‐contribute to icaritin‐induced nephrotoxicity

Huijun Sun, Fangjun Wang, Q. Meng, 2022, Phytotherapy research : PTR.

Liver uptake of cefditoren is mediated by OATP1B1 and OATP2B1 in humans and Oatp1a1, Oatp1a4, and Oatp1b2 in rats

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2017 .

Involvement of Organic Anion-Transporting Polypeptides in the Hepatic Uptake of Dioscin in Rats and Humans

Huijun Sun, Jinyong Peng, Q. Meng, 2013, Drug Metabolism and Disposition.

Title Involvement of organic anion-transporting polypeptides in the hepatic uptake of dioscin in rat and human

Huijun Sun, Jinyong Peng, Q. Meng, 2013 .

Potent anti-inflammatory effect of dioscin mediated by suppression of TNF-α-induced VCAM-1, ICAM-1and EL expression via the NF-κB pathway.

Huijun Sun, Jinyong Peng, Yue Jin, 2015, Biochimie.

RAPID AND SENSITIVE DETERMINATION OF JBP485 BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY AND ITS APPLICATION IN PHARMACOKINETICS IN RAT

Huijun Sun, Changyuan Wang, Kexin Liu, 2011 .

Dioscin strengthens the efficiency of adriamycin in MCF-7 and MCF-7/ADR cells through autophagy induction: More than just down-regulation of MDR1

Huijun Sun, Jinyong Peng, Zhihao Liu, 2016, Scientific Reports.

Dasatinib reverses the multidrug resistance of breast cancer MCF-7 cells to doxorubicin by downregulating P-gp expression via inhibiting the activation of ERK signaling pathway

Huijun Sun, Jinyong Peng, Zhihao Liu, 2015, Cancer biology & therapy.

Pharmacokinetics and mechanism of intestinal absorption of JBP485 in rats.

Y. Sugiyama, A. Tsuji, Q. Meng, 2010, Drug metabolism and pharmacokinetics.

Organic anion transporters and PI3K–AKT–mTOR pathway mediate the synergistic anticancer effect of pemetrexed and rhein

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2020, Journal of cellular physiology.

Afatinib Decreases P‐Glycoprotein Expression to Promote Adriamycin Toxicity of A549T Cells

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Journal of cellular biochemistry.

Protective Effects of Calycosin Against CCl4-Induced Liver Injury with Activation of FXR and STAT3 in Mice

Huijun Sun, Jinyong Peng, Q. Meng, 2014, Pharmaceutical Research.

Targeting P-Glycoprotein: Nelfinavir Reverses Adriamycin Resistance in K562/ADR Cells

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Cellular Physiology and Biochemistry.

Design and synthesis of phosphoryl-substituted diphenylpyrimidines (Pho-DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors: Targeted treatment of B lymphoblastic leukemia cell lines.

Huijun Sun, Xiaodong Ma, Q. Meng, 2017, Bioorganic & medicinal chemistry.

Discovery of Novel Bruton's Tyrosine Kinase (BTK) Inhibitors Bearing a N,9-Diphenyl-9H-purin-2-amine Scaffold.

Xiaodong Ma, Changyuan Wang, Jinyong Peng, 2016, ACS medicinal chemistry letters.

Hepatoprotective effect of rhein against methotrexate‐induced liver toxicity

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, European journal of pharmacology.

Dioscin reduces ovariectomy-induced bone loss by enhancing osteoblastogenesis and inhibiting osteoclastogenesis.

Huijun Sun, Jinyong Peng, Y. Qi, 2016, Pharmacological research.

Rhizoma Dioscoreae Nipponicae polysaccharides protect HUVECs from H2O2-induced injury by regulating PPARγ factor and the NADPH oxidase/ROS-NF-κB signal pathway.

Huijun Sun, Jinyong Peng, Yue Jin, 2015, Toxicology letters.

P-gp, MRP2 and OAT1/OAT3 mediate the drug-drug interaction between resveratrol and methotrexate.

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2016, Toxicology and applied pharmacology.

Phosphamide-containing diphenylpyrimidine analogues (PA-DPPYs) as potent focal adhesion kinase (FAK) inhibitors with enhanced activity against pancreatic cancer cell lines.

Xiaodong Ma, Bin Wu, Changyuan Wang, 2017, Bioorganic & medicinal chemistry.

C-2 (E)-4-(Styryl)aniline substituted diphenylpyrimidine derivatives (Sty-DPPYs) as specific kinase inhibitors targeting clinical resistance related EGFRT790M mutant.

Jinyong Peng, Xiaodong Ma, Q. Meng, 2017, Bioorganic & medicinal chemistry.

Resveratrol Increases Anti‐Proliferative Activity of Bestatin Through Downregulating P‐Glycoprotein Expression Via Inhibiting PI3K/Akt/mTOR Pathway in K562/ADR Cells

Zhihao Liu, Changyuan Wang, Kexin Liu, 2016, Journal of cellular biochemistry.

MDR1 and OAT1/OAT3 Mediate the Drug-Drug Interaction between Puerarin and Methotrexate

Huijun Sun, Jinyong Peng, Q. Meng, 2013, Pharmaceutical Research.

Preparative Isolation and Purification of Two Phenylpropanoids from Daphne giraldii Nitsche by HSCCC

Xiaochi Ma, Changyuan Wang, Kexin Liu, 2010 .

Dioscin protects against ANIT-induced cholestasis via regulating Oatps, Mrp2 and Bsep expression in rats.

Huijun Sun, Jinyong Peng, Q. Meng, 2016, Toxicology and applied pharmacology.

Protective Effects of Alisol B 23-Acetate Via Farnesoid X Receptor-Mediated Regulation of Transporters and Enzymes in Estrogen-Induced Cholestatic Liver Injury in Mice

Huijun Sun, Zhihao Liu, Q. Meng, 2015, Pharmaceutical Research.

Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis.

Huijun Sun, Xiaodong Ma, Yue Jin, 2019, Pharmacological research.

Enhancement effect of resveratrol on the intestinal absorption of bestatin by regulating PEPT1, MDR1 and MRP2 in vivo and in vitro.

Huijun Sun, Zhihao Liu, Q. Meng, 2015, International journal of pharmaceutics.

JBP485, A Dual Inhibitor of Organic Anion Transporters (OATs) and Renal Dehydropeptidase-I (DHP-I), Protects Against Imipenem-Induced Nephrotoxicity

Huijun Sun, Jing Chen, Q. Meng, 2022, Frontiers in Pharmacology.

MDR1 and OAT1/OAT3 Mediate the Drug-Drug Interaction between Puerarin and Methotrexate

Huijun Sun, Jinyong Peng, Q. Meng, 2014, Pharmaceutical Research.

Protective effects of glycyrrhizic acid against non‐alcoholic fatty liver disease in mice

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2017, European journal of pharmacology.

Promising galactose-decorated biodegradable poloxamer 188-PLGA diblock copolymer nanoparticles of resibufogenin for enhancing liver cancer therapy

Xiaochi Ma, Changyuan Wang, Yan Tian, 2017, Drug delivery.

Emodin-Loaded PLGA-TPGS Nanoparticles Combined with Heparin Sodium-Loaded PLGA-TPGS Nanoparticles to Enhance Chemotherapeutic Efficacy Against Liver Cancer

Changyuan Wang, Yan Tian, M. Gao, 2016, Pharmaceutical Research.

Yangonin modulates lipid homeostasis, ameliorates cholestasis and cellular senescence in alcoholic liver disease via activating nuclear receptor FXR.

Huijun Sun, Q. Meng, Changyuan Wang, 2021, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Dioscin reduces lipopolysaccharide-induced inflammatory liver injury via regulating TLR4/MyD88 signal pathway.

Jinyong Peng, Y. Qi, Li-na Xu, 2016, International immunopharmacology.

Substrate-dependent inhibition of hypericin on human carboxylesterase 2: implications for herb-drug combination.

Huijun Sun, Tongyi Dou, J. Chen, 2022, Current drug metabolism.

Combination of dihydromyricetin and ondansetron strengthens antiproliferative efficiency of adriamycin in K562/ADR through downregulation of SORCIN: A new strategy of inhibiting P‐glycoprotein

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2018, Journal of cellular physiology.

Enhancement effect of P-gp inhibitors on the intestinal absorption and antiproliferative activity of bestatin.

Huijun Sun, Jinyong Peng, Q. Meng, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Hepatoprotection of yangonin against hepatic fibrosis in mice via farnesoid X receptor activation.

Huijun Sun, Xiaodong Ma, Q. Meng, 2019, International immunopharmacology.

Corrigendum to "Dioscin attenuates renal ischemia/reperfusion injury by inhibiting theTLR4/MyD88 signaling pathway via up-regulation of HSP70" [Pharmacol. Res. 100 (2015) 341-352].

Huijun Sun, Jinyong Peng, Y. Qi, 2019, Pharmacological Research.

The integrative analysis of competitive endogenous RNA regulatory networks in osteoporosis

Huijun Sun, Yue Jin, Changyuan Wang, 2022, Scientific Reports.

Design, synthesis and activity evaluation of isopropylsulfonyl-substituted 2,4- diarylaminopyrimidine derivatives as FAK inhibitors for the potential treatment of pancreatic cancer.

Xiaodong Ma, Changyuan Wang, Xu Zheng, 2022, European journal of medicinal chemistry.

Naringin regulates cholesterol homeostasis and inhibits inflammation via modulating NF-κB and ERK signaling pathways in vitro.

Huijun Sun, Jinyong Peng, Yue Jin, 2016, Die Pharmazie.

Biotransformation of isoimperatorin by Cunninghamella blakesleana AS 3.970

H. Kuang, Changyuan Wang, Kexin Liu, 2013 .

Effect of JBP485 on obstructive jaundice is related to regulation of renal Oat1, Oat3 and Mrp2 expression in ANIT-treated rats

Huijun Sun, Q. Meng, Xiaochi Ma, 2012, Peptides.

JBP485 improves gentamicin-induced acute renal failure by regulating the expression and function of Oat1 and Oat3 in rats.

Huijun Sun, Jinyong Peng, Q. Meng, 2013, Toxicology and applied pharmacology.

Piperacillin enhances the inhibitory effect of tazobactam on β-lactamase through inhibition of organic anion transporter 1/3 in rats

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2018, Asian Journal of Pharmaceutical Sciences.

Aspirin and Probenecid Inhibit Organic Anion Transporter 3–Mediated Renal Uptake of Cilostazol and Probenecid Induces Metabolism of Cilostazol in the Rat

Huijun Sun, Jinyong Peng, Q. Meng, 2014, Drug Metabolism and Disposition.

Two new ent-kaurane diterpenoids from Pteris semipinnata

Xiaochi Ma, Bao-jing Zhang, Changyuan Wang, 2013, Journal of Asian natural products research.

Two new diterpene and sesquiterpene from Pteris dispar

N. Liang, Li Li, Bao-jing Zhang, 2011 .

Catalpol-Induced AMPK Activation Alleviates Cisplatin-Induced Nephrotoxicity through the Mitochondrial-Dependent Pathway without Compromising Its Anticancer Properties

Huijun Sun, Xiaodong Ma, Q. Meng, 2021, Oxidative medicine and cellular longevity.

Organic Anion-Transporting Polypeptide and Efflux Transporter-Mediated Hepatic Uptake and Biliary Excretion of Cilostazol and Its Metabolites in Rats and Humans.

Huijun Sun, Zhihao Liu, Q. Meng, 2017, Journal of pharmaceutical sciences.

Pharmacokinetic changes of cefdinir and cefditoren and its molecular mechanisms in acute kidney injury in rats

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2018, The Journal of pharmacy and pharmacology.

Scutellarin ameliorates nonalcoholic fatty liver disease through the PPARγ/PGC-1α-Nrf2 pathway

Yufeng Fu, Huijun Sun, Jinyong Peng, 2018, Free radical research.

Farnesoid X receptor overexpression prevents hepatic steatosis through inhibiting AIM2 inflammasome activation in nonalcoholic fatty liver disease.

Q. Meng, Changyuan Wang, Haifeng Luo, 2023, Biochimica et biophysica acta. Molecular basis of disease.

Honokiol Prodrug Nanoparticles Based on In Situ Albumin Binding for Long Circulation and High Tumor Uptake.

Xiaodong Ma, Y. Qi, Youwei Xu, 2021, ACS medicinal chemistry letters.

Circ_0114581 promotes osteogenic differentiation of BMSCs via the MiR-155-5p/HNRNPA3 axis.

Huijun Sun, Yue Jin, Q. Meng, 2023, Life sciences.

Phosphocreatine Promotes Osteoblastic Activities in H2O2-induced MC3T3-E1 Cells by Regulating SIRT1/FOXO1/PGC-1α Signaling Pathway.

Huijun Sun, Yue Jin, Q. Meng, 2020, Current Pharmaceutical Biotechnology.

Alpha-lipoic Acid Prevents Bone Loss in Type 2 Diabetes and Postmenopausal Osteoporosis Coexisting Conditions by Modulating the YAP/Glut4 Pathway.

Changyuan Wang, Mozhen Liu, Chunfang Zhang, 2024, Cell biochemistry and biophysics.

Identifying the Dominant Contribution of Human Cytochrome P450 2J2 to the Metabolism of Rivaroxaban, an Oral Anticoagulant

Huijun Sun, Q. Meng, Changyuan Wang, 2020, Cardiovascular Drugs and Therapy.

Epigenetic modification of TWIST1 in macrophages promotes hypertension-induced atherosclerotic plaque instability.

Yue Jin, Q. Meng, Changyuan Wang, 2023, International immunopharmacology.

BMSC-derived extracellular vesicles promoted osteogenesis via Axin2 inhibition by delivering MiR-16-5p.

Huijun Sun, Yue Jin, Changyuan Wang, 2023, International immunopharmacology.

Synthesis and biological activity of thieno[3,2-d]pyrimidines as potent JAK3 inhibitors for the treatment of idiopathic pulmonary fibrosis.

Huijun Sun, Xiaodong Ma, Changyuan Wang, 2019, Bioorganic & medicinal chemistry.

Protective Effects of Calycosin Against CCl4-Induced Liver Injury with Activation of FXR and STAT3 in Mice

Huijun Sun, Jinyong Peng, Q. Meng, 2015, Pharmaceutical Research.