A. Berson

发表

Hepatitis after intravenous buprenorphine misuse in heroin addicts.

P. Marcellin, D. Pessayre, D. Valla, 2001, Journal of hepatology.

Cell-generated nitric oxide inactivates rat hepatocyte mitochondria in vitro but reacts with hemoglobin in vivo.

D. Pessayre, B. Fromenty, A. Berson, 1996, Gastroenterology.

Dual effect of amiodarone on mitochondrial respiration. Initial protonophoric uncoupling effect followed by inhibition of the respiratory chain at the levels of complex I and complex II.

D. Pessayre, B. Fromenty, A. Berson, 1990, The Journal of pharmacology and experimental therapeutics.

Uncoupling of rat and human mitochondria: a possible explanation for tacrine-induced liver dysfunction.

D. Pessayre, B. Fromenty, G. Feldmann, 1996, Gastroenterology.

Central role of mitochondria in drug-induced liver injury

D. Pessayre, B. Fromenty, R. Moreau, 2012, Drug metabolism reviews.

Prediction of drug-induced liver injury in humans by using in vitro methods: the case of ximelagatran.

P. Beaune, D. Pessayre, T. Andersson, 2008, Toxicology in vitro : an international journal published in association with BIBRA.

Possible role of HLA in hepatotoxicity. An exploratory study in 71 patients with drug-induced idiosyncratic hepatitis.

D. Pessayre, B. Fromenty, A. Berson, 1994, Journal of hepatology.

Mitochondria in Steatohepatitis

D. Pessayre, B. Fromenty, A. Berson, 2001, Seminars in liver disease.

Effects of female sex hormones on mitochondria: possible role in acute fatty liver of pregnancy.

D. Pessayre, B. Fromenty, G. Feldmann, 1995, The American journal of physiology.

Decreased mitochondrial oxidation of fatty acids in pregnant mice: Possible relevance to development of acute fatty liver of pregnancy

D. Pessayre, B. Fromenty, G. Feldmann, 1993, Hepatology.

Tacrine inhibits topoisomerases and DNA synthesis to cause mitochondrial DNA depletion and apoptosis in mouse liver

D. Pessayre, B. Fromenty, A. Sutton, 2003, Hepatology.

Subliminal Fas stimulation increases the hepatotoxicity of acetaminophen and bromobenzene in mice

D. Pessayre, G. Feldmann, A. Berson, 2004, Hepatology.

Inhibitory effects of nilutamide, a new androgen receptor antagonist, on mouse and human liver cytochrome P-450.

D. Pessayre, A. Berson, P. Lettéron, 1989, Biochemical pharmacology.

Generation of free radicals during the reductive metabolism of the nitroaromatic compound, nilutamide.

D. Pessayre, B. Fromenty, C. Wolf, 1991, The Journal of pharmacology and experimental therapeutics.

Genetic predisposition to drug hepatotoxicity: Role in hepatitis caused by amineptine, a tricyclic antidepressant

D. Pessayre, A. Berson, P. Dansette, 1989, Hepatology.

Mechanism for the protective effects of silymarin against carbon tetrachloride-induced lipid peroxidation and hepatotoxicity in mice. Evidence that silymarin acts both as an inhibitor of metabolic activation and as a chain-breaking antioxidant.

G. Labbe, D. Pessayre, B. Fromenty, 1990, Biochemical pharmacology.

An alcoholic binge causes massive degradation of hepatic mitochondrial DNA in mice.

D. Pessayre, B. Fromenty, G. Feldmann, 1999, Gastroenterology.

Microvesicular steatosis and steatohepatitis: role of mitochondrial dysfunction and lipid peroxidation.

D. Pessayre, B. Fromenty, A. Berson, 1997, Journal of hepatology.

Migration of microsomal autoantigens to the hepatocyte plasma membrane

D. Pessayre, A. Berson, M. Robin, 2000 .

Vesicular transport of newly synthesized cytochromes P4501A to the outside of rat hepatocyte plasma membranes.

D. Pessayre, M. Maratrat, A. Berson, 2000, The Journal of pharmacology and experimental therapeutics.

Interleukin-2 overexpresses c-myc and down-regulates cytochrome P-450 in rat hepatocytes.

D. Pessayre, A. Berson, M. Robin, 1999, The Journal of pharmacology and experimental therapeutics.

High hepatic glutathione stores alleviate Fas-induced apoptosis in mice.

D. Pessayre, B. Fromenty, G. Feldmann, 2007, Journal of hepatology.

The Anti-Inflammatory Drug, Nimesulide Uncouples Mitochondria and Induces Mitochondrial Permeability Transition in Human Hepatoma Cells. Protection by Albumin.

D. Pessayre, G. Feldmann, A. Berson, 2006 .

Mesalazine (5-aminosalicylic acid) induced chronic hepatitis

P. Marcellin, D. Pessayre, C. Degott, 1999, Gut.

Drug induced Hepatotoxicity and Mitochondrial Dysfunction

D. Pessayre, B. Fromenty, A. Berson, 2002 .

Peliosis hepatis induced by 6-thioguanine administration.

D. Pessayre, D. Valla, C. Degott, 1988, Gut.

Renoprotective effects of the 21-aminosteroid U74389G in ischemia-reperfusion injury and cold storage preservation.

A. Berson, L. Salinas-Madrigal, C. Combs, 1997, Transplantation.

Ibuprofen administration attenuates serum TNF-alpha levels, hepatic glutathione depletion, hepatic apoptosis and mouse mortality after Fas stimulation.

D. Pessayre, G. Feldmann, A. Berson, 2008, Toxicology and applied pharmacology.

Toxicity of the antiandrogen flutamide in isolated rat hepatocytes.

D. Pessayre, B. Fromenty, A. Berson, 1994, The Journal of pharmacology and experimental therapeutics.

Mitochondrial involvement in drug-induced liver injury.

D. Pessayre, B. Fromenty, A. Berson, 2010, Handbook of experimental pharmacology.

Evaluation of human blood lymphocytes as a model to study the effects of drugs on human mitochondria. Effects of low concentrations of amiodarone on fatty acid oxidation, ATP levels and cell survival.

D. Pessayre, B. Fromenty, A. Berson, 1993, Biochemical pharmacology.

Carbon tetrachloride-mediated lipid peroxidation induces early mitochondrial alterations in mouse liver

B. Fromenty, A. Fautrel, A. Berson, 2012, Laboratory Investigation.

The Anti-Inflammatory Drug, Nimesulide (4-Nitro-2-phenoxymethane-sulfoanilide), Uncouples Mitochondria and Induces Mitochondrial Permeability Transition in Human Hepatoma Cells: Protection by Albumin

D. Pessayre, G. Feldmann, C. Wolf, 2006, Journal of Pharmacology and Experimental Therapeutics.

Hepatic Mitochondrial DNA Depletion after an Alcohol Binge in Mice: Probable Role of Peroxynitrite and Modulation by Manganese Superoxide Dismutase

D. Pessayre, B. Fromenty, R. Moreau, 2010, Journal of Pharmacology and Experimental Therapeutics.

Metabolic activation of the nitroaromatic antiandrogen flutamide by rat and human cytochromes P-450, including forms belonging to the 3A and 1A subfamilies.

P. Beaune, C. Wolf, A. Berson, 1993, The Journal of pharmacology and experimental therapeutics.

Interest of ESR in determining the mechanisms of drug toxicity : application to the antiandrogen nilutamide

D. Pessayre, C. Wolf, A. Berson, 1994 .

Genetically determined oxidation polymorphism and drug hepatotoxicity. Study of 51 patients.

F. Iglicki, A. Berson, H. Fouin-Fortunet, 1989, Journal of hepatology.

Generation of free radicals during the reductive metabolism of nilutamide by lung microsomes: possible role in the development of lung lesions in patients treated with this anti-androgen.

D. Pessayre, B. Fromenty, C. Wolf, 1992, Biochemical pharmacology.

Mechanisms for experimental buprenorphine hepatotoxicity: major role of mitochondrial dysfunction versus metabolic activation.

D. Pessayre, A. Sutton, G. Feldmann, 2001, Journal of hepatology.

Stereoselective and nonstereoselective effects of ibuprofen enantiomers on mitochondrial beta-oxidation of fatty acids.

G. Labbe, D. Pessayre, B. Fromenty, 1990, The Journal of pharmacology and experimental therapeutics.

Opening of the mitochondrial permeability transition pore causes matrix expansion and outer membrane rupture in fas‐mediated hepatic apoptosis in mice

D. Pessayre, G. Feldmann, A. Berson, 2000, Hepatology.

Downregulation of cytochromes P450 in growth-stimulated rat hepatocytes: role of c-Myc induction and impaired C/EBP binding to DNA.

P. Beaune, D. Pessayre, T. Cresteil, 2003, Journal of hepatology.

Premature oxidative aging of hepatic mitochondrial DNA in Wilson's disease.

D. Pessayre, B. Fromenty, C. Degott, 1997, Gastroenterology.

Multiple hepatic mitochondrial DNA deletions suggest premature oxidative aging in alcoholic patients.

D. Pessayre, B. Fromenty, M. Beaugrand, 1997, Journal of hepatology.

Amiodarone inhibits the mitochondrial beta-oxidation of fatty acids and produces microvesicular steatosis of the liver in mice.

G. Labbe, D. Pessayre, B. Fromenty, 1990, The Journal of pharmacology and experimental therapeutics.

Pharmacogenetics of human erythrocyte thiopurine methyltransferase activity in a French population.

D. Pessayre, A. Berson, Y. Horsmans, 1991, British journal of clinical pharmacology.

Withdrawal of life support, altruistic suicide, fratricidal killing and euthanasia by lymphocytes: different forms of drug-induced hepatic apoptosis.

D. Pessayre, A. Berson, M. Robin, 1999, Journal of hepatology.

Steatohepatitis-inducing drugs trigger cytokeratin cross-links in hepatocytes. Possible contribution to Mallory-Denk body formation.

D. Pessayre, A. Berson, M. Robin, 2008, Toxicology in vitro : an international journal published in association with BIBRA.

Steatohepatitis-inducing drugs cause mitochondrial dysfunction and lipid peroxidation in rat hepatocytes.

D. Pessayre, B. Fromenty, C. Moreau, 1998, Gastroenterology.

Decrease in hepatic cytochrome P450 after interleukin-2 immunotherapy.

P. Beaune, G. Labbe, D. Pessayre, 1999, Biochemical pharmacology.

Toxicity of alpidem, a peripheral benzodiazepine receptor ligand, but not zolpidem, in rat hepatocytes: role of mitochondrial permeability transition and metabolic activation.

D. Pessayre, A. Sutton, T. Tordjmann, 2001, The Journal of pharmacology and experimental therapeutics.

Mechanism for the hepatotoxicity of the antiandrogen, nilutamide. Evidence suggesting that redox cycling of this nitroaromatic drug leads to oxidative stress in isolated hepatocytes.

D. Pessayre, B. Fromenty, A. Berson, 1992, The Journal of pharmacology and experimental therapeutics.

Polymorphism of dextromethorphan oxidation in a French population.

G. Labbe, D. Pessayre, A. Berson, 1987, British journal of clinical pharmacology.

Inhibition by salicylic acid of the activation and thus oxidation of long chain fatty acids. Possible role in the development of Reye's syndrome.

D. Pessayre, B. Fromenty, C. Degott, 1991, The Journal of pharmacology and experimental therapeutics.

Effects of various tetracycline derivatives on in vitro and in vivo beta-oxidation of fatty acids, egress of triglycerides from the liver, accumulation of hepatic triglycerides, and mortality in mice.

G. Labbe, D. Pessayre, B. Fromenty, 1991, Biochemical pharmacology.

Inhibition by nilutamide of the mitochondrial respiratory chain and ATP formation. Possible contribution to the adverse effects of this antiandrogen.

D. Pessayre, B. Fromenty, C. Wolf, 1994, The Journal of pharmacology and experimental therapeutics.

[Hepatitis caused by cyproheptadine (Periactine). A case and review of the literature].

D. Pessayre, A. Berson, J. Benhamou, 1988, Gastroenterologie clinique et biologique.

Increased ethane exhalation, an in vivo index of lipid peroxidation, in alcohol-abusers.

D. Pessayre, B. Fromenty, C. Degott, 1993, Gut.

Amineptine, a tricyclic antidepressant, inhibits the mitochondrial oxidation of fatty acids and produces microvesicular steatosis of the liver in mice.

G. Labbe, D. Pessayre, C. Degott, 1988, The Journal of pharmacology and experimental therapeutics.

[Hepatitis probably caused by Plethoryl. Apropos of 7 cases].

D. Pessayre, C. Degott, A. Berson, 1988, Gastroentérologie Clinique et Biologique.

Central role of mitochondria in drug-induced liver injury

D. Pessayre, B. Fromenty, R. Moreau, 2012, Drug metabolism reviews.