H. Champion

S. Russell, E. Kasper, J. Hare, 2007, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

[Pulmonary hypertension in chronic lung diseases].

F. Martinez, W. Seeger, J. Barberà, 2014, Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir.

A Critical Role for the Protein Apoptosis Repressor With Caspase Recruitment Domain in Hypoxia-Induced Pulmonary Hypertension

M. Halushka, M. Crow, R. Kitsis, 2011, Circulation.

Post-translational inactivation of endothelial nitric oxide synthase in the transgenic sickle cell mouse penis.

A. Burnett, T. Bivalacqua, H. Champion, 2011, The journal of sexual medicine.

A rat model of Peyronie's disease associated with a decrease in erectile activity and an increase in inducible nitric oxide synthase protein expression.

W. Hellstrom, S. Sikka, T. Bivalacqua, 2000, The Journal of urology.

Risk of transmission of bovine spongiform encephalopathy to humans in the United States: report of the Council on Scientific Affairs. American Medical Association.

M. Williams, H. Champion, M. K. Khan, 1999, JAMA.

Adverse ventricular remodeling and exacerbated NOS uncoupling from pressure-overload in mice lacking the beta3-adrenoreceptor.

D. Kass, M. Halushka, A. Hale, 2009, Journal of molecular and cellular cardiology.

Resistin-like molecule-beta in scleroderma-associated pulmonary hypertension.

R. Johns, Stephen C. Yang, R. Tuder, 2009, American journal of respiratory cell and molecular biology.

Increased expression of arginase II in human diabetic corpus cavernosum: in diabetic-associated erectile dysfunction.

W. Hellstrom, T. Bivalacqua, H. Champion, 2001 .

Altered high-energy phosphate metabolism predicts contractile dysfunction and subsequent ventricular remodeling in pressure-overload hypertrophy mice.

D. Kass, V. P. Chacko, M. Stuber, 2007, American journal of physiology. Heart and circulatory physiology.

[Pro11,D-Ala12]angiotensin I has rapid onset vasoconstrictor activity in the cat.

H. Champion, P. Kadowitz, E. Garrison, 1997, The American journal of physiology.

[Pro11,d-Ala12]angiotensin I has rapid onset vasoconstrictor activity in the cat.

H. Champion, P. Kadowitz, E. Garrison, 1997, American journal of physiology. Endocrinology and metabolism.

Heart failure-associated alterations in troponin I phosphorylation impair ventricular relaxation-afterload , and force-frequency responses and systolic function

D. Kass, E. Takimoto, J. Duncan, 2006 .

Gene therapy techniques for the delivery of endothelial nitric oxide synthase to the lung for pulmonary hypertension.

S. N. Murthy, T. Bivalacqua, H. Champion, 2010, Methods in molecular biology.

Mesenchymal stem cells alone or ex vivo gene modified with endothelial nitric oxide synthase reverse age-associated erectile dysfunction.

S. N. Murthy, B. Taylor, W. Hellstrom, 2007, American journal of physiology. Heart and circulatory physiology.

Gene therapy techniques for the delivery of endothelial nitric oxide synthase to the corpora cavernosa for erectile dysfunction.

W. Hellstrom, T. Bivalacqua, H. Champion, 2004, Methods in molecular biology.

Awareness, diagnosis, and treatment of depression

Larry S. Goldman, L. Goldman, H. Champion, 1999, Journal of General Internal Medicine.

Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability.

M. Gladwin, A. Schechter, B. Diwan, 2006, Blood.

&bgr;2-Adrenergic Receptor-Coupled Phosphoinositide 3-Kinase Constrains cAMP-Dependent Increases in Cardiac Inotropy Through Phosphodiesterase 4 Activation

A. Shoukas, A. Phan, J. Hare, 2010, Anesthesia and analgesia.

Obesity-induced tissue free radical generation: an in vivo immuno-spin trapping study.

Simon C Watkins, B. Freeman, R. Mason, 2012, Free radical biology & medicine.

Gene transfer of extracellular SOD to the penis reduces O2-* and improves erectile function in aged rats.

W. Hellstrom, A. Abdel‐Mageed, T. Bivalacqua, 2003, American journal of physiology. Heart and circulatory physiology.

Overexpression of arginase in the aged mouse penis impairs erectile function and decreases eNOS activity: influence of in vivo gene therapy of anti-arginase.

A. Burnett, W. Hellstrom, T. Bivalacqua, 2007, American journal of physiology. Heart and circulatory physiology.

Targeting Nrf2 with the triterpenoid CDDO- imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice

M. Sporn, S. Biswal, Masayuki Yamamoto, 2009, Proceedings of the National Academy of Sciences.

Acute phosphodiesterase 5 inhibition mimics hemodynamic effects of B-type natriuretic peptide and potentiates B-type natriuretic peptide effects in failing but not normal canine heart.

D. Kass, R. Tunin, H. Champion, 2007, Journal of the American College of Cardiology.

Role of Nitric Oxide in the Pathophysiology of Heart Failure

J. Hare, H. Champion, Michel W. Skaf, 2004, Heart Failure Reviews.

Emerging therapeutic targets in nitric oxide-dependent cardiac disease

J. Hare, H. Champion, 2001, Expert opinion on therapeutic targets.

ORIGINAL RESEARCH—BASIC SCIENCE: Superoxide Anion Production in the Rat Penis Impairs Erectile Function in Diabetes: Influence of In Vivo Extracellular Superoxide Dismutase Gene Therapy

W. Hellstrom, T. Bivalacqua, H. Champion, 2005 .

Endothelial dysfunction in erectile dysfunction: role of the endothelium in erectile physiology and disease.

W. Hellstrom, T. Bivalacqua, H. Champion, 2003, Journal of andrology.

PI 3 K rescues the detrimental effects of chronic Akt activation in the heart during ischemia / reperfusion injury

D. Kass, P. Anversa, A. Leri, 2018 .

PI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injury.

D. Kass, P. Anversa, A. Leri, 2005, The Journal of clinical investigation.

Diagnosis and Management of Secondary Pulmonary Hypertension

H. Champion, A. Hemnes, 2006 .

vascular responses Peroxynitrite does not impair pulmonary and systemic

P. Barnes, L. Roberts, T. Bivalacqua, 2015 .

Peroxynitrite does not impair pulmonary and systemic vascular responses.

A. Kaye, T. Bivalacqua, B. Nossaman, 2004, Journal of applied physiology.

Calcium handler mishandles heart

D. Kass, H. Champion, 2004, Nature Medicine.

Compartmentalization of Cardiac &bgr;-Adrenergic Inotropy Modulation by Phosphodiesterase Type 5

D. Kass, E. Takimoto, H. Champion, 2007 .

Fatty acid nitroalkenes ameliorate glucose intolerance and pulmonary hypertension in high-fat diet-induced obesity.

Simon C Watkins, M. Gladwin, B. Freeman, 2014, Cardiovascular research.

Increased levels of uric acid predict haemodynamic compromise in patients with heart failure independently of B-type natriuretic peptide levels

S. Russell, E. Kasper, J. Hare, 2007, Heart.

Positive inotropic and lusitropic effects of HNO/NO− in failing hearts: Independence from β-adrenergic signaling

D. Kass, D. Wink, H. Champion, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Reversal of Cardiac Hypertrophy and Fibrosis From Pressure Overload by Tetrahydrobiopterin: Efficacy of Recoupling Nitric Oxide Synthase as a Therapeutic Strategy

James B. Mitchell, D. Kass, M. Halushka, 2008, Circulation.

Phosphodiesterase regulation of nitric oxide signaling.

D. Kass, E. Takimoto, H. Champion, 2007, Cardiovascular research.

PDE5A Inhibitor Treatment of Persistent Pulmonary Hypertension After Mechanical Circulatory Support

D. Yuh, S. Russell, J. Orens, 2008, Circulation. Heart failure.

Endothelin Axis Is Upregulated in Human and Rat Right Ventricular Hypertrophy

D. Ross, I. Rebeyka, E. Michelakis, 2013, Circulation research.

Combination Therapy in Pulmonary Arterial Hypertension—Targeting the Nitric Oxide and Prostacyclin Pathways

H. Olschewski, H. Champion, G. Kovacs, 2021, Journal of cardiovascular pharmacology and therapeutics.

Pulmonary Hypertension: A Common Complication of Left Heart Disease

H. Champion, 2011 .

Pulmonary vascular lesions are common in SIV- and SHIV-env-infected macaques.

M. Gladwin, T. Reinhart, A. Morris, 2011, AIDS research and human retroviruses.

impairment in nitric oxide bioavailability Hemolysis in sickle cell mice causes pulmonary hypertension due to global

M. Gladwin, A. Schechter, B. Diwan, 2012 .

Chronic hypoxia induces right heart failure in caveolin-1-/- mice.

Andres I Rodriguez, H. Champion, S. Shiva, 2012, American journal of physiology. Heart and circulatory physiology.

Hypoxia-induced mitogenic factor has proangiogenic and proinflammatory effects in the lung via VEGF and VEGF receptor-2.

R. Johns, H. Champion, Qingning Su, 2006, American journal of physiology. Lung cellular and molecular physiology.

Schistosomiasis-induced experimental pulmonary hypertension: role of interleukin-13 signaling.

G. Butrous, A. Zaiman, T. Wynn, 2010, The American journal of pathology.

Role of the TGF- b /Alk5 Signaling Pathway in Monocrotaline-induced Pulmonary Hypertension

P. Sehgal, A. Zaiman, R. Tuder, 2008 .

Pulmonary vascular responses to exercise: a haemodynamic observation

R. Naeije, G. Lewis, H. Champion, 2012, European Respiratory Journal.

Combination Therapy Improves Vascular Volume in Female Rats with Pulmonary Hypertension.

H. Champion, R. White, R. Ambrosini, 2019, American journal of physiology. Lung cellular and molecular physiology.

Adrenomedullin-(22-52) antagonizes vasodilator responses to CGRP but not adrenomedullin in the cat.

H. Champion, P. Kadowitz, W. Murphy, 1997, The American journal of physiology.

The heart in scleroderma.

H. Champion, 2008, Rheumatic diseases clinics of North America.

Injection drug use as a "second hit" in the pathogenesis of HIV-associated pulmonary hypertension.

M. Gladwin, A. Morris, H. Champion, 2012, American journal of respiratory and critical care medicine.

Regression of chronic hypoxic pulmonary hypertension by simvastatin.

R. Johns, R. Tuder, P. Hassoun, 2007, American journal of physiology. Lung cellular and molecular physiology.

Tissue factor pathway inhibitor overexpression inhibits hypoxia-induced pulmonary hypertension.

R. Simari, T. White, H. Champion, 2010, American journal of respiratory cell and molecular biology.

Role of calcitonin gene-related peptide (CGRP) in chronic hypoxia-induced pulmonary hypertension in the mouse Influence of gene transfer in vivo

D. Kass, T. Bivalacqua, H. Champion, 2002, Regulatory Peptides.

Chronic Hypoxia-induced Pulmonary Hypertension in the Mouse Related Peptide to the Lung Attenuates − in Vivo Gene Transfer of Prepro-calcitonin Gene in Vivo Gene Transfer of Prepro-calcitonin Gene–related Peptide to the Lung Attenuates Chronic Hypoxia-induced Pulmonary Hypertension in the Mouse

T. Bivalacqua, D. Heistad, K. Toyoda, 2022 .

Elevated RhoA/Rho‐kinase activity in the aged rat penis: mechanism for age‐associated erectile dysfunction

A. Burnett, T. Bivalacqua, H. Champion, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Analysis of responses to hAmylin, hCGRP, and hADM in isolated resistance arteries from the mesenteric vascular bed of the rat

D. Coy, T. Bivalacqua, H. Champion, 2001, Peptides.

Distribution, functional role, and signaling mechanism of adrenomedullin receptors in the rat adrenal gland

G. Albertin, G. Mazzocchi, G. Nussdorfer, 1999, Peptides.

Endothelial Arginase II: A Novel Target for the Treatment of Atherosclerosis

A. Shoukas, N. Alp, D. Christianson, 2008, Circulation research.

Knockdown of Arginase I Restores NO Signaling in the Vasculature of Old Rats

A. Shoukas, J. Hare, H. Champion, 2006, Hypertension.

Arginase Reciprocally Regulates Nitric Oxide Synthase Activity and Contributes to Endothelial Dysfunction in Aging Blood Vessels

A. Shoukas, J. Hare, H. Champion, 2003, Circulation.

Adenoviral gene transfer of endothelial nitric-oxide synthase (eNOS) partially restores normal pulmonary arterial pressure in eNOS-deficient mice

T. Giles, T. Bivalacqua, H. Champion, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Regulation of endothelial thrombomodulin expression by inflammatory cytokines is mediated by activation of nuclear factor-kappa B.

R. H. Sohn, K. Gardner, D. Johns, 2005, Blood.

Identification of candidate genes in scleroderma-related pulmonary arterial hypertension.

C. Cheadle, K. Barnes, D. Grigoryev, 2008, Translational research : the journal of laboratory and clinical medicine.

FIZZ1/RELM&agr;, a Novel Hypoxia-Induced Mitogenic Factor in Lung With Vasoconstrictive and Angiogenic Properties

R. Johns, H. Champion, Dechun Li, 2003, Circulation research.

A Inhibitor Treatment of Persistent Pulmonary Hypertension After Mechanical Circulatory Support

D. Yuh, S. Russell, J. Orens, 2008 .

Stress cardiomyopathy after intravenous administration of catecholamines and beta-receptor agonists.

James O. Mudd, I. Wittstein, H. Champion, 2009, Journal of the American College of Cardiology.

Isolated right ventricular dysfunction in patients with human immunodeficiency virus.

M. Gladwin, C. Kessinger, M. Simon, 2014, Journal of cardiac failure.

Analysis of effects of bosentan (Ro 47-0203), a nonpeptide endothelin ETA/ETB receptor antagonist, in the hind-limb vascular bed of the cat.

H. Champion, P. Kadowitz, J. Filep, 1998, Canadian journal of physiology and pharmacology.

Compartmentalization of Cardiac (cid:1) -Adrenergic Inotropy Modulation by Phosphodiesterase Type 5 Molecular Cardiology

D. Kass, E. Takimoto, H. Champion, 2007 .

Pharmacologic management of peripheral vascular disease.

H. Champion, P. Kadowitz, D. B. McNamara, 1998, The Surgical clinics of North America.

Comparison of the NO and HNO donating properties of diazeniumdiolates: primary amine adducts release HNO in Vivo.

D. Kass, K. Houk, D. Wink, 2005, Journal of medicinal chemistry.

Sildenafil inhibits superoxide formation and prevents endothelial dysfunction in a mouse model of secondhand smoke induced erectile dysfunction.

S. Biswal, A. Burnett, T. Bivalacqua, 2009, The Journal of urology.

NO Effect on Penile Blood Flow and Lower Genitourinary Tract Function

W. Hellstrom, T. Bivalacqua, H. Champion, 2000 .

The endogenous mu-opioid agonists, endomorphin 1 and 2, have vasodilator activity in the hindquarters vascular bed of the rat.

A. Kastin, H. Champion, P. Kadowitz, 1997, Life sciences.

The endogenous mu-opioid receptor agonists endomorphins 1 and 2 have novel hypotensive activity in the rabbit.

A. Kastin, H. Champion, L. Hackler, 1997, Biochemical and biophysical research communications.

Pulmonary hypertension in chronic lung diseases.

F. Martinez, W. Seeger, J. Barberà, 2013, Journal of the American College of Cardiology.

A Novel Acquisition Technique to Utilize Swan-Ganz Catheter data as a Surrogate for High-fidelity Micromanometry within the Right Ventricle and Pulmonary Circuit

M. Simon, H. Champion, T. Bachman, 2013, Cardiovascular engineering and technology.

Chronic oral administration of the arginase inhibitor 2(S)-amino-6-boronohexanoic acid (ABH) improves erectile function in aged rats.

A. Burnett, J. H. Kim, T. Bivalacqua, 2012, Journal of andrology.

Superoxide dismutase - a target for gene therapeutic approach to reduce oxidative stress in erectile dysfunction.

S. N. Murthy, T. Bivalacqua, H. Champion, 2010, Methods in molecular biology.

Gene transfer of endothelial nitric oxide synthase to the penis augments erectile responses in the aged rat.

L. Ignarro, T. Bivalacqua, H. Champion, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Induction of penile erection by intracavernosal and transurethral administration of novel nitric oxide donors in the cat.

P. C. Doherty, J. Saavedra, L. Keefer, 1999, The Journal of urology.

Cyclohexanone contamination from extracorporeal circuits impairs cardiovascular function.

A. Shoukas, L. Santhanam, H. Champion, 2009, American journal of physiology. Heart and circulatory physiology.

A novel right-heart catheterization technique for in vivo measurement of vascular responses in lungs of intact mice.

H. Champion, P. Kadowitz, A. Hyman, 2000, American journal of physiology. Heart and circulatory physiology.

Long-acting oral phosphodiesterase inhibition preconditions against reperfusion injury in an experimental lung transplantation model.

W. Baumgartner, H. Champion, Eric S. Weiss, 2009, The Journal of thoracic and cardiovascular surgery.

Effect of combination endothelial nitric oxide synthase gene therapy and sildenafil on erectile function in diabetic rats

T. Bivalacqua, H. Champion, M. Usta, 2004, International Journal of Impotence Research.

N-TERMINAL PRO-BRAIN NATRIURETIC PEPTIDE IS A UNIQUE MARKER OF POOR SURVIVAL IN SCLERODERMA-RELATED PULMONARY ARTERIAL HYPERTENSION

L. Hummers, P. Hassoun, S. Mathai, 2009 .

Sex and Menopause Differences in Response to Tadalafil: 6-Minute Walk Distance and Time to Clinical Worsening

J. Cleveland, H. Champion, M. Mathier, 2015, Pulmonary circulation.

Estrogens Exacerbate Development Of Occlusive Pulmonary Arterial Hypertension And Formation Of Plexiform Lesions

H. Champion, S. Tofovic, O. Rafikova, 2012, ATS 2012.

First Successful Lung Transplantation for Sickle Cell Disease with Severe Pulmonary Arterial Hypertension and Pulmonary Veno-Occlusive Disease

M. Gladwin, S. Yousem, J. Pilewski, 2013, Pulmonary circulation.

Role of Nitric Oxide in the Skeletal Muscle Vascular Bed

H. Champion, P. Kadowitz, 2000 .

Erection capability is potentiated by chronic sildenafil treatment: role of blood flow-induced endothelial nitric oxide synthase phosphorylation

A. Burnett, H. Champion, Tongyun Liu, 2005 .

Biocompatibility Assessment of the CentriMag-Novalung Adult ECMO Circuit in a Model of Acute Pulmonary Hypertension

Salim E. Olia, M. Simon, W. Wagner, 2014, ASAIO journal.

A typical case of atypical dyspnea.

H. Champion, J. Spahr, Eric M. Davis, 2013, Annals of the American Thoracic Society.

Novel catheterization technique for the in vivo measurement of pulmonary vascular responses in rats.

H. Lippton, H. Champion, P. Kadowitz, 1998, The American journal of physiology.

Results Effects of Acute Pressure Overload on Endocardial Thrombomodulin Expression

D. Kass, H. Champion, J. K. Donahue, 2006 .

Pharmacotherapy for erectile dysfunction.

T. Bivalacqua, H. Champion, P. Kadowitz, 2000, Trends in pharmacological sciences.

Responses to angiotensin peptides are mediated by AT1 receptors in the rat.

H. Champion, P. Kadowitz, M. A. Czapla, 1998, The American journal of physiology.

Patients with Stress-Induced (Takotsubo) Cardiomyopathy Have an Increased Prevalence of Mood Disorders and Antidepressant Use Compared to Patients with Acute Myocardial Infarction

S. Schulman, I. Wittstein, H. Champion, 2007 .

Is exercise‐induced pulmonary hypertension ready for prime time in systemic sclerosis?

V. Steen, H. Champion, 2011, International journal of clinical practice. Supplement.

Relationship Between Baseline Pulmonary Capillary Wedge Pressure And Response To Sildenafil Treatment In Pulmonary Arterial Hypertension

H. Champion, L. Rubin, M. Mathier, 2012, ATS 2012.

Sildenafil Citrate-Restored eNOS and PDE5 Regulation in Sickle Cell Mouse Penis Prevents Priapism Via Control of Oxidative/Nitrosative Stress

A. Burnett, T. Bivalacqua, H. Champion, 2013, PloS one.

Increased expression of arginase II in human diabetic corpus cavernosum: in diabetic-associated erectile dysfunction

T. Bivalacqua, H. Champion, P. Kadowitz, 2002, International Journal of Impotence Research.

Inhibitory effects of candesartan on responses to angiotensin peptides in the hindquarters vascular bed of the cat.

D. Lambert, H. Champion, P. Kadowitz, 1998, Canadian journal of physiology and pharmacology.

Comparison of the Inhibitory Actions of Angiotensin AT1 Receptor Antagonists in the Peripheral Vascular Bed

D. Lambert, T. Bivalacqua, H. Champion, 1998 .

Analysis of the effects of candesartan in the mesenteric vascular bed of the cat.

H. Champion, P. Kadowitz, 1997, HYPERTENSION.

Analysis of responses to human synthetic adrenomedullin and calcitonin gene-related peptides in the hindlimb vascular bed of the cat.

D. Lambert, H. Champion, P. Kadowitz, 1997 .

Analysis of responses to angiotensin I and angiotensin I-(3-10) in the mesenteric vascular bed of the cat.

H. Champion, P. Kadowitz, E. Garrison, 1996, European journal of pharmacology.

[MPR14]-rADM(14-50), a novel analog of adrenomedullin, possesses potent vasodilator activity in the hindlimb vascular bed of the cat.

D. Lambert, H. Champion, P. Kadowitz, 1996, Life Science.

Dysregulation of cGMP‐dependent protein kinase 1 (PKG‐1) impairs erectile function in diabetic rats: influence of in vivo gene therapy of PKG1α

W. Hellstrom, T. Bivalacqua, H. Champion, 2007, BJU international.

Gene transfer of endothelial nitric oxide synthase partially restores nitric oxide synthesis and erectile function in streptozotocin diabetic rats.

W. Hellstrom, A. Abdel‐Mageed, T. Bivalacqua, 2003, The Journal of urology.

Direct effects of selective type 5 phosphodiesterase inhibitors alone or with other vasodilators on the erectile response in cats.

P. C. Doherty, T. Bivalacqua, H. Champion, 2001, The Journal of urology.

Feline penile erection induced by transurethral administration of sodium nitroprusside

P. C. Doherty, W. Hellstrom, T. Bivalacqua, 1999, Urological research.

Role of PDE5a in cardiac stress response

D. Kass, E. Takimoto, H. Champion, 2005 .

Endothelial nitric oxide synthase keeps erection regulatory function balance in the penis.

A. Burnett, T. Bivalacqua, H. Champion, 2007, European urology.

Influence of Nimodipine on Vasoconstrictor Responses in the Hindquarters Vascular Bed of the Cat

H. Champion, P. Kadowitz, 1998, The Journal of pharmacy and pharmacology.

Analysis of Vasodilator Responses to Peroxynitrite in the Hindlimb Vascular Bed of the Cat

T. Bivalacqua, B. Nossaman, H. Champion, 2007, Journal of cardiovascular pharmacology.

Role of Cyclooxygenase-2 in the Generation of Vasoactive Prostanoids in the Rat Pulmonary and Systemic Vascular Beds

T. Bivalacqua, H. Champion, P. Kadowitz, 2003, Circulation.

Establishment of a transgenic sickle-cell mouse model to study the pathophysiology of priapism.

M. Gladwin, A. Burnett, T. Bivalacqua, 2009, The journal of sexual medicine.

Direct sGC activation bypasses NO scavenging reactions of intravascular free oxy-hemoglobin and limits vasoconstriction.

M. Gladwin, J. Stasch, D. Tabima, 2013, Antioxidants & redox signaling.

Stem and endothelial progenitor cells in erectile biology: future therapeutic applications and potential biomarker for erectile dysfunction

A. Burnett, T. Bivalacqua, H. Champion, 2008 .

Mitochondria in Cardiovascular Physiology and Disease Nox-derived ROS are acutely activated in pressure overload pulmonary hypertension : indications for a seminal role for mitochondrial Nox 4

H. Champion, S. Shiva, J. Baust, 2013 .

Mitochondria in Cardiovascular Physiology and Disease Nox-derived ROS are acutely activated in pressure overload pulmonary hypertension : indications for a seminal role for mitochondrial Nox 4

H. Champion, S. Shiva, J. Baust, 2013 .

Tone-Dependent Vasodilator Responses to Proadrenomedullin NH2-Terminal 20 Peptide in the Hindquarters Vascular Bed of the Rat

D. Lambert, H. Champion, P. Kadowitz, 1997, Peptides.

Effects of Acute Intravenous Iloprost on Right Ventricular Hemodynamics in Rats with Chronic Pulmonary Hypertension

H. Champion, T. Bachman, N. Zeineh, 2014, Pulmonary circulation.

New clinical and ultrastructural findings in hydroxychloroquine-induced cardiomyopathy--a report of 2 cases.

M. Halushka, H. Champion, L. Barouch, 2007, Human pathology.

eNOS Gene Therapy Exacerbates Hepatic Ischemia–Reperfusion Injury in Diabetes: A Role for eNOS Uncoupling

Mark R. Duranski, D. Lefer, H. Champion, 2006, Circulation research.

Role for eNOS Uncoupling eNOS Gene Therapy Exacerbates Hepatic Ischemia-Reperfusion Injury in Diabetes : A Print

Mark R. Duranski, D. Lefer, H. Champion, 2006 .

Adeno-associated viral gene transfer of dominant negative RhoA enhances erectile function in rats.

W. Hellstrom, T. Bivalacqua, H. Champion, 2002, Biochemical and biophysical research communications.

Right heart function

H. Champion, A. Hemnes, 2011 .

Responses to angiotensin peptides are mediated by AT1 receptors in the rat.

H. Champion, P. Kadowitz, M. A. Czapla, 1998, American journal of physiology. Endocrinology and metabolism.

Abstract 3379: cGMP Specific Phosphodiesterase Type 5A Activity is Regulated by S-nitrosylation at Cys 181

D. Kass, H. Champion, J. Eyk, 2008 .

Analysis of vasoconstrictor responses to histamine in the hindlimb vascular bed of the rabbit.

D. Lambert, T. Bivalacqua, H. Champion, 1999, American journal of physiology. Regulatory, integrative and comparative physiology.

Analysis of vasoconstrictor responses to histamine in the hindlimb vascular bed of the rabbit.

D. Lambert, T. Bivalacqua, H. Champion, 1999, The American journal of physiology.

Phosphodiesterase-5A (PDE5A) is localized to the endothelial caveolae and modulates NOS3 activity.

M. Halushka, G. Hesketh, A. Zaiman, 2011, Cardiovascular research.

Effects of Phentolamine on Responses to PAMP in the Hindquarters Vascular Bed of the Rat

A. Kaye, B. Nossaman, H. Champion, 1997, Journal of cardiovascular pharmacology and therapeutics.

Certified athletic trainers in secondary schools: report of the council on scientific affairs, american medical association.

J. Lyznicki, H. Champion, J. Riggs, 1999, Journal of athletic training.

Cavernous neurotomy causes hypoxia and fibrosis in rat corpus cavernosum.

W. Hellstrom, A. Abdel‐Mageed, T. Bivalacqua, 2003, Journal of andrology.

Clinical differences between idiopathic and scleroderma-related pulmonary hypertension.

J. Krishnan, L. Hummers, P. Hassoun, 2006, Arthritis and rheumatism.

Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy

D. Kass, Yibin Wang, E. Takimoto, 2005, Nature Medicine.

Early changes in vasoreactivity after simulated microgravity are due to an upregulation of the endothelium-dependent nitric oxide/cGMP pathway

A. Shoukas, J. Hare, H. Champion, 2010, European Journal of Applied Physiology.

Hyponatremia predicts right heart failure and poor survival in pulmonary arterial hypertension.

P. Hassoun, S. Mathai, H. Champion, 2008, American journal of respiratory and critical care medicine.

Survival of Pulmonary Arterial Hypertension Related to Systemic Sclerosis: A Single Center Longitudinal Study.

A. Zaiman, L. Hummers, P. Hassoun, 2009, ATS 2009.

Effects of U-37883A, a vascular selective KATP+ channel antagonist, in the pulmonary and hindlimb circulation.

T. McMahon, H. Champion, D. Cheng, 1996, American Journal of Physiology.

Vasodilator Responses to the Endomorphin Peptides, but Not Nociceptin/OFQ, Are Mediated by Nitric Oxide Release

A. Kastin, T. Bivalacqua, H. Champion, 1999, Annals of the New York Academy of Sciences.

Nitric oxide release mediates vasodilator responses to endomorphin 1 but not nociceptin/OFQ in the hindquarters vascular bed of the rat

A. Kastin, T. Bivalacqua, H. Champion, 1998, Peptides.

Endomorphin 1 and 2, the endogenous mu-opioid agonists, produce biphasic changes in systemic arterial pressure in the cat.

A. Kastin, D. Lambert, T. Bivalacqua, 1998, Life sciences.

Endomorphin 1 and 2 Have Vasodepressor Activity in the Anesthetized Mouse

A. Kastin, H. Champion, P. Kadowitz, 1998, Peptides.

d-[Ala2]endomorphin 2 and endomorphin 2 have nitric oxide-dependent vasodilator activity in rats.

H. Champion, P. Kadowitz, 1998, American journal of physiology. Heart and circulatory physiology.

Endomorphin 1 and 2, endogenous mu-opioid agonists, decrease systemic arterial pressure in the rat.

A. Kastin, H. Champion, L. Hackler, 1998, Life sciences.

Endomorphin 1 and 2, Endogenous Ligands for the μ-opioid Receptor, Decrease Cardiac Output, and Total Peripheral Resistance in the Rat

A. Kastin, H. Champion, L. Hackler, 1997, Peptides.

Subacute Hemolysis in Sickle Cell Mice Causes Priapism Secondary to NO Imbalance and PDE5 Dysregulation.

A. Burnett, T. Bivalacqua, N. Sopko, 2015, The journal of sexual medicine.

Combat Wound Initiative program.

C. Attinger, S. Ahlers, P. Pasquina, 2010, Military medicine.

Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats.

A. Shoukas, Y. Oh, D. Christianson, 2009, Journal of applied physiology.

Phosphodiesterase type 5: expanding roles in cardiovascular regulation.

D. Kass, J. Beavo, H. Champion, 2007, Circulation research.

The change in B-type natriuretic peptide levels over time predicts significant rejection in cardiac transplant recipients.

S. Russell, M. Halushka, D. Judge, 2009, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

Nerve regeneration and elastin formation within poly(glycerol sebacate)-based synthetic arterial grafts one-year post-implantation in a rat model.

Anne M Robertson, Debaditya Dutta, Xinjie Duan, 2014, Biomaterials.

Nociceptin, an Endogenous Ligand for the ORL1 Receptor, Decreases Cardiac Output and Total Peripheral Resistance in the Rat

H. Champion, P. Kadowitz, M. A. Czapla, 1997, Peptides.

Accuracy of Doppler echocardiography in the hemodynamic assessment of pulmonary hypertension.

M. Corretti, P. Hassoun, H. Champion, 2009, American journal of respiratory and critical care medicine.

Robust Adenoviral and Adeno-Associated Viral Gene Transfer to the In Vivo Murine Heart: Application to Study of Phospholamban Physiology

Saptarsi M. Haldar, D. Kass, Lili Wang, 2003, Circulation.

hemodynamic changes of pulmonary hypertension ) induces the vascular and α (HIMF/FIZZ1/RELMmitogenic factor

R. Johns, M. Crow, Zongming Fu, 2011 .

Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) induces the vascular and hemodynamic changes of pulmonary hypertension.

R. Johns, M. Crow, H. Champion, 2009, American journal of physiology. Lung cellular and molecular physiology.

Effect of tumour necrosis factor‐α (TNF‐α) and interferon‐γ (IFN‐γ) on human sperm motility, viability and motion parameters

B. Aggarwal, S. Sikka, H. Champion, 1997 .

Vasodilator responses to adenosine and hyperemia are mediated by A(1) and A(2) receptors in the cat vascular bed.

D. Lambert, T. Bivalacqua, H. Champion, 2002, American journal of physiology. Regulatory, integrative and comparative physiology.

Vasodilator responses to ATP and UTP are not dependent on nitric oxide release, K+ATP channel activation, or the release of vasodilator prostaglandins in the hindlimb vascular bed of the cat

H. Champion, P. Kadowitz, 2000 .

Responses to human CGRP, ADM, and PAMP in human thymic arteries.

D. Coy, T. Bivalacqua, H. Champion, 2003, American journal of physiology. Regulatory, integrative and comparative physiology.

Vasorelaxant responses to endomorphins, nociceptin, albuterol, and adrenomedullin in isolated rat aorta.

H. Champion, P. Kadowitz, J. R. Jeter, 2000, Life sciences.

Nociceptin, a novel endogenous ligand for the ORL1 receptor, dilates isolated resistance arteries from the rat

H. Champion, P. Kadowitz, R. L. Pierce, 1998, Regulatory Peptides.

Nociceptin, An Endogenous Ligand for the ORL1 Receptor, has Vasodilator Activity in the Hindquarters Vascular Bed of the Rat

H. Champion, P. Kadowitz, M. A. Czapla, 1997, Peptides.

NO release and the opening of K+ATP channels mediate vasodilator responses to histamine in the cat.

H. Champion, P. Kadowitz, 1997, The American journal of physiology.

Attenuated RhoA/Rho-kinase signaling in penis of transgenic sickle cell mice.

A. Ross, A. Burnett, T. Bivalacqua, 2010, Urology.

Feasibility of the use of phosphodiesterase type 5 inhibitors in a pharmacologic prevention program for recurrent priapism.

A. Burnett, T. Bivalacqua, H. Champion, 2006, The journal of sexual medicine.

Long-term oral phosphodiesterase 5 inhibitor therapy alleviates recurrent priapism.

T. Bivalacqua, H. Champion, A. Burnett, 2006, Urology.

Phosphodiesterase-5A dysregulation in penile erectile tissue is a mechanism of priapism.

D. Kass, A. Burnett, E. Takimoto, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Phosphodiesterase type 5 inhibitor therapy for priapism

A. Burnett, T. Bivalacqua, H. Champion, 2008 .

RhoA/Rho-kinase suppresses endothelial nitric oxide synthase in the penis: A mechanism for diabetes-associated erectile dysfunction

W. Hellstrom, T. Bivalacqua, H. Champion, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Sildenafil promotes eNOS activation and inhibits NADPH oxidase in the transgenic sickle cell mouse penis.

A. Burnett, T. Bivalacqua, H. Champion, 2014, The journal of sexual medicine.

1202: Long-Term Phosphodiesterase Type 5 Inhibitor Therapy Reduces Priapic Activity in Transgenic Sickle Cell Mice

W. Mason, A. Burnett, T. Bivalacqua, 2006 .

Erection Capability Is Potentiated by Long-Term Sildenafil Treatment: Role of Blood Flow-Induced Endothelial Nitric-Oxide Synthase Phosphorylation

A. Burnett, H. Champion, Tongyun Liu, 2005, Molecular Pharmacology.

Transcriptomic Biomarkers for Individual Risk Assessment in New-Onset Heart Failure

Joshua M. Hare, Edward K. Kasper, S. Russell, 2008, Circulation.

Early Treatment with Fumagillin, an Inhibitor of Methionine Aminopeptidase-2, Prevents Pulmonary Hypertension in Monocrotaline-Injured Rats

Ferhaan Ahmad, A. Saqi, D. Kass, 2012, PloS one.

NADPH oxidase-derived ROS and the regulation of pulmonary vessel tone.

H. Champion, P. Pagano, G. Frazziano, 2012, American journal of physiology. Heart and circulatory physiology.

Structural and Mechanical Adaptations of Right Ventricle Free Wall Myocardium to Pressure Overload

M. Sacks, D. Valdez-Jasso, M. Simon, 2014, Annals of Biomedical Engineering.

Hemodynamic Modulation of Endocardial Thromboresistance

D. Kass, H. Champion, J. K. Donahue, 2006, Circulation.

"Happiness" and stress cardiomyopathy (apical ballooning syndrome/takotsubo syndrome).

H. Champion, Dingxin Qin, Sandeep M Patel, 2014, International journal of cardiology.

Gene therapy for erectile dysfunction: fact or fiction?

W. Hellstrom, T. Bivalacqua, H. Champion, 2006, European urology.

Alternatively spliced neuronal nitric oxide synthase mediates penile erection.

S. Snyder, A. Sawa, Paul L Huang, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Comprehensive invasive and noninvasive approach to the right ventricle-pulmonary circulation unit: state of the art and clinical and research implications.

P. Hassoun, E. Michelakis, H. Champion, 2009, Circulation.

Research Implications VentriclePulmonary Circulation Unit: State of the Art and Clinical and Comprehensive Invasive and Noninvasive Approach to the Right

P. Hassoun, E. Michelakis, H. Champion, 2009 .

Future perspectives for the treatment of pulmonary arterial hypertension.

M. Humbert, D. Stewart, H. Ghofrani, 2009, Journal of the American College of Cardiology.

Diagnosis and assessment of pulmonary arterial hypertension.

Horst Olschewski, Adam Torbicki, A. Torbicki, 2009, Journal of the American College of Cardiology.

The variable natural history of idiopathic dilated cardiomyopathy.

S. Russell, D. Judge, K. Parakh, 2012, The Israel Medical Association journal : IMAJ.

Transcriptomic Biomarkers for the Accurate Diagnosis of Myocarditis

S. Russell, R. Hruban, E. Kasper, 2011, Circulation.

Posttranslational modification of constitutive nitric oxide synthase in the penis.

A. Ross, A. Burnett, T. Bivalacqua, 2009, Journal of andrology.

Gene transfer of endothelial nitric oxide synthase to the lung of the mouse in vivo. Effect on agonist-induced and flow-mediated vascular responses.

L. Ortiz, T. Bivalacqua, D. Heistad, 1999, Circulation research.

cGMP Catabolism by Phosphodiesterase 5A Regulates Cardiac Adrenergic Stimulation by NOS3-Dependent Mechanism

M. Zaccolo, D. Kass, M. Mongillo, 2004, Circulation research.

Pulmonary hypertension due to left heart diseases.

F. Martinez, W. Seeger, J. Barberà, 2013, Journal of the American College of Cardiology.

Nociceptin, an endogenous ligand for the ORL1 receptor, has novel hypotensive activity in the rat.

H. Champion, P. Kadowitz, 1997, Life sciences.

Decreases in Systemic Arterial and Hindquarters Perfusion Pressure in Response to Nociceptin Are Not Inhibited by Naloxone in the Rat

H. Champion, P. Kadowitz, M. A. Czapla, 1997, Peptides.

Role of AT(1) receptors and autonomic nervous system in mediating acute pressor responses to ANG II in anesthetized mice.

T. Bivalacqua, H. Champion, P. Kadowitz, 1999, The American journal of physiology.

Role of AT1 receptors and autonomic nervous system in mediating acute pressor responses to ANG II in anesthetized mice.

T. Bivalacqua, H. Champion, P. Kadowitz, 1999, American journal of physiology. Endocrinology and metabolism.

Modulation of In Vivo Cardiac Function by Myocyte-Specific Nitric Oxide Synthase-3

D. Kass, Yibin Wang, E. Takimoto, 2004, Circulation research.

The gene expression profile of patients with new-onset heart failure reveals important gender-specific differences.

S. Russell, E. Kasper, K. Baughman, 2010, European heart journal.

Cardiac CD47 Drives Left Ventricular Heart Failure Through Ca2+‐CaMKII‐Regulated Induction of HDAC3

R. Bilonick, C. S. St. Croix, C. McTiernan, 2014, Journal of the American Heart Association.

Tricuspid annular displacement predicts survival in pulmonary hypertension.

T. Abraham, M. Corretti, P. Hassoun, 2006, American journal of respiratory and critical care medicine.

L-arginine therapy in acute myocardial infarction: the Vascular Interaction With Age in Myocardial Infarction (VINTAGE MI) randomized clinical trial.

D. Kass, L. Becker, J. Hare, 2006, JAMA.

Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load.

D. Kass, Yibin Wang, E. Takimoto, 2005, The Journal of clinical investigation.

Exposure to inhaled particulate matter impairs cardiac function in senescent mice.

W. Mitzner, E. Takimoto, C. Tankersley, 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

Characterization of Right Ventricular Remodeling in Pulmonary Hypertension Associated With Patient Outcomes by 3-Dimensional Wall Motion Tracking Echocardiography

M. Gladwin, J. Gorcsan, M. Simon, 2015, Circulation. Cardiovascular imaging.

Compartmentation of Cyclic Nucleotide Signaling in the Heart: The Role of Cyclic Nucleotide Phosphodiesterases Overview of PDEs and their Regulation Regulation of Phosphodiesterase 3 (PDE3) and Inducible cAMP Early Repressor in the Heart cAMP Specific Phosphodiesterase-4 Enzymes in the Cardiovascula

D. Kass, J. Beavo, H. Champion, 2007 .

When to initiate intravenous therapy and/or refer.

H. Champion, 2013, The American journal of cardiology.

Analysis of Vasodilator Responses to Novel Nitric Oxide Donors in the Hindquarters Vascular Bed of the Cat

J. Saavedra, L. Keefer, T. Bivalacqua, 2001, Journal of cardiovascular pharmacology.

Safety of over-the-counter inhalers for asthma: report of the council on scientific affairs.

R. Altman, S. Deitchman, H. Champion, 2000, Chest.

Mechanisms and potential therapeutic targets for folic acid in cardiovascular disease.

D. Kass, C. Vrints, J. Timmermans, 2008, American journal of physiology. Heart and circulatory physiology.

Expression, activity, and pro-hypertrophic effects of PDE5A in cardiac myocytes.

D. Kass, M. Crow, B. O’Rourke, 2008, Cellular signalling.

Endothelial dysfunction is present only in the microvasculature and microcirculation of early diffuse systemic sclerosis patients.

C. Kwoh, R. Domsic, T. Medsger, 2014, Clinical and experimental rheumatology.

Analysis of responses to adrenomedullin-(13-52) in the pulmonary vascular bed of rats.

J. Mehta, H. Lippton, J. Chang, 1998, American journal of physiology. Heart and circulatory physiology.

Catabolism by Phosphodiesterase 5 A Regulates Cardiac Adrenergic Stimulation

M. Zaccolo, D. Kass, M. Mongillo, 2004 .

Comparative responses to α,β-methylene-ATP in cat pulmonary, mesenteric, and hindquarter vascular beds

E. Inscho, T. Bivalacqua, H. Champion, 2002 .

Application of Evicel to cavernous nerves of the rat does not influence erectile function in vivo.

T. Guzzo, E. Schaeffer, A. Burnett, 2008, Urology.

[Tyr1]-nociceptin and nociceptin have similar naloxone-insensitive erectile activity in the cat.

T. Bivalacqua, H. Champion, P. Kadowitz, 1998, Journal of andrology.

Endothelium-specific gene and stem cell-based therapy for erectile dysfunction.

A. Burnett, T. Bivalacqua, H. Champion, 2008, Asian journal of andrology.

Novel catheterization technique for the in vivo measurement of pulmonary vascular responses in rats.

H. Lippton, H. Champion, P. Kadowitz, 1998, American journal of physiology. Heart and circulatory physiology.

Cardiac CD 47 Drives Left Ventricular Heart Failure Through Ca 2 +-CaMKII-Regulated Induction of HDAC 3

R. Bilonick, C. McTiernan, H. Champion, 2014 .

Activated RhoA/Rho kinase impairs erectile function after cavernous nerve injury in rats.

C. Stief, A. Burnett, T. Bivalacqua, 2010, The Journal of urology.

Analysis of responses to angiotensin II in the mouse

T. Bivalacqua, H. Champion, P. Kadowitz, 2001, Journal of the renin-angiotensin-aldosterone system : JRAAS.

Cardiopulmonary function in individuals with HIV infection in the antiretroviral therapy era

M. Gladwin, F. Sciurba, C. Kessinger, 2012, AIDS.

Comparison of Responses to T-Kinin and Bradykinin in the Mesenteric Vascular Bed of the Cat

T. Bivalacqua, H. Champion, P. Kadowitz, 1997, Peptides.

Conductance catheter-based assessment of arterial input impedance, arterial function, and ventricular-vascular interaction in mice.

Pascal Verdonck, Patrick Segers, Nikos Stergiopulos, 2005, American journal of physiology. Heart and circulatory physiology.

Endothelin‐1[1–31], acting as an ETA‐receptor selective agonist, stimulates proliferation of cultured rat zona glomerulosa cells

G. Mazzocchi, G. Nussdorfer, H. Champion, 2000, FEBS letters.

Heart: Application to Study of Phospholamban Physiology Robust Adenoviral and Adeno-Associated Viral Gene Transfer to the In Vivo Murine

Saptarsi M. Haldar, D. Kass, R. Simari, 2015 .

Reply: potential differentiation of human mesenchymal stem cell transplanted in rat corpus cavernosum toward endothelial or smooth muscle cells

T. Bivalacqua, H. Champion, P. Kadowitz, 2007, International Journal of Impotence Research.

Vasodepressor responses to [D-Ala2]-endomorphin 2 (TAPP) are mediated by an L-NAME-sensitive mechanism in the rat.

H. Champion, P. Kadowitz, 1999, Journal of cardiovascular pharmacology.

1041: Endothelial Nitric Oxide Synthase is a Homeostatic Regulator of RHOA/RHO-Kinase Activity in the Penis

A. Burnett, T. Bivalacqua, H. Champion, 2005 .

Differential responses to ATPgammaS in the mesenteric and hindlimb vascular bed of the cat.

T. Bivalacqua, H. Champion, P. Kadowitz, 2001, Life sciences.

Analysis of responses to adrenomedullin-(13-52) in the pulmonary vascular bed of rats.

J. Mehta, H. Lippton, H. Champion, 1998, The American journal of physiology.

Pulmonary hypertension in chronic lung diseases.

F. Martinez, W. Seeger, J. Barberà, 2013, Journal of the American College of Cardiology.

R-(-)-alpha-methyl-histamine has nitric oxide-mediated vasodilator activity in the mesenteric vascular bed of the cat.

H. Champion, P. Kadowitz, 1998, European journal of pharmacology.

Vasodilator Responses to ATP and UTP are cAMP Dependent in the Mesenteric Vascular Bed of the Cat

T. Bivalacqua, H. Champion, P. Kadowitz, 2001, Journal of cardiovascular pharmacology and therapeutics.

Transcriptomic biomarkers for the accurate diagnosis of myocarditis.

R. Hruban, E. Kasper, K. Baughman, 2011, Circulation.

Evaluation of nitric oxide synthase and arginase in the induction of a Peyronie's-like condition in the rat.

W. Hellstrom, A. Abdel‐Mageed, S. Sikka, 2001, Journal of andrology.

[Tyr1]-nociceptin, a novel nociceptin analog, decreases systemic arterial pressure by a naloxone-insensitive mechanism in the rat.

H. Champion, P. Kadowitz, 1997, Biochemical and biophysical research communications.

The influence of candesartan and PD123319 on responses to angiotensin II in the hindquarters vascular bed of the rat.

D. Lambert, T. Bivalacqua, H. Champion, 1999, Journal of the American Society of Nephrology : JASN.

Analysis of Vasodepressor Responses to Nociceptin and Nociceptin Analogs in the Systemic Vascular Bed of the Anesthetized Rabbit In Vivo

T. Bivalacqua, H. Champion, P. Kadowitz, 1998, Journal of cardiovascular pharmacology and therapeutics.

[Tyr1]-nociceptin has naloxone-insensitive vasodilator activity in the hindquarters vascular bed of the rat.

H. Champion, P. Kadowitz, 1997, Life sciences.

Vasodilator responses to acetylcholine, bradykinin, and substance P are mediated by a TEA-sensitive mechanism.

H. Champion, P. Kadowitz, 1997, The American journal of physiology.

Potentiation of erectile response and cAMP accumulation by combination of prostaglandin E1 and rolipram, a selective inhibitor of the type 4 phosphodiesterase (PDE 4).

P. C. Doherty, S. Sikka, T. Bivalacqua, 1999, The Journal of urology.

J. Beavo, H. Champion, David A. Kass, 2007 .

Sildenafil inhibits superoxide formation and prevents endothelial dysfunction in a mouse model of secondhand smoke induced erectile dysfunction.

S. Biswal, A. Burnett, T. Bivalacqua, 2009, The Journal of urology.

Stem and endothelial progenitor cells in erection biology

A. Burnett, T. Bivalacqua, H. Champion, 2008, International Journal of Impotence Research.

Endothelial Krüppel-like factor 4 modulates pulmonary arterial hypertension.

H. Champion, Rongli Zhang, J. Martínez-González, 2014, American journal of respiratory cell and molecular biology.

Cellular, Pharmacological, and Biophysical Evaluation of Explanted Lungs from a Patient with Sickle Cell Disease and Severe Pulmonary Arterial Hypertension

Ferhaan Ahmad, M. Gladwin, J. Milošević, 2013, Pulmonary circulation.

NADPH oxidase-derived ROS and the regulation of pulmonary vessel tone.

H. Champion, P. Pagano, G. Frazziano, 2012, American journal of physiology. Heart and circulatory physiology.

Transcriptomic Biomarkers for the Accurate Diagnosis of Myocarditis

Cleveland Clinic Foundation, E. Kasper, I. Wittstein, 2011, Circulation.

Transcriptomic Biomarkers for Individual Risk Assessment in New-Onset Heart Failure

E. Kasper, K. Baughman, J. Hare, 2008, Circulation.

Tricuspid annular displacement predicts survival in pulmonary hypertension.

T. Abraham, M. Corretti, P. Hassoun, 2006, American journal of respiratory and critical care medicine.

Gene transfer of endothelial nitric oxide synthase to the lung of the mouse in vivo. Effect on agonist-induced and flow-mediated vascular responses.

T. Bivalacqua, D. Heistad, K. Toyoda, 1999, Circulation Research.

Angiogenic Properties , a Novel Hypoxia-Induced Mitogenic Factor in Lung With α FIZZ 1 / RELM

R. Johns, H. Champion, Dechun Li, 2003 .

Accuracy of Doppler echocardiography in the hemodynamic assessment of pulmonary hypertension.

M. Corretti, P. Hassoun, H. Champion, 2009, American journal of respiratory and critical care medicine.

L-163,491 is a partial angiotensin AT(1) receptor agonist in the hindquarters vascular bed of the cat.

H. Champion, P. Kadowitz, E. Garrison, 2000, European journal of pharmacology.

Role Of Nitric Oxide In Mediating Vasodilator Responses To Opioid Peptides In The Rat

A. Kastin, T. Bivalacqua, H. Champion, 2002, Clinical and experimental pharmacology & physiology.

and of Phosphodiesterase and cAMP Early Repressor in the Heart the for Expanding in Type Expanding Roles in Cardiovascular Regulation

J. Beavo, H. Champion, David A. Kass, 2007 .

and of Phosphodiesterase and cAMP Early Repressor in the Heart the for Expanding in Type Expanding Roles in Cardiovascular Regulation

J. Beavo, H. Champion, David A. Kass, 2007 .

Compartmentalization of Cardiac (cid:1) -Adrenergic Inotropy Modulation by Phosphodiesterase Type 5 Molecular Cardiology

D. Kass, E. Takimoto, H. Champion, 2007 .

Toward systems biology of pulmonary hypertension.

Ferhaan Ahmad, N. Kaminski, H. Champion, 2012, Circulation.

Endothelial nitric oxide synthase gene therapy for erectile dysfunction.

A. Burnett, W. Hellstrom, T. Bivalacqua, 2005, Current pharmaceutical design.

PDE5A inhibition attenuates bleomycin-induced pulmonary fibrosis and pulmonary hypertension through inhibition of ROS generation and RhoA/Rho kinase activation.

A. Zaiman, H. Champion, A. Hemnes, 2008, American journal of physiology. Lung cellular and molecular physiology.

Comprehensive Invasive and Noninvasive Approach to the Right Ventricle–Pulmonary Circulation Unit State of the Art and Clinical and Research Implications catheterization allows determination of prognostic Pulmonary Vascular Diseases

E. Michelakis, H. Champion, P. Hassoun, 2009 .

Heart failure-associated alterations in troponin I phosphorylation impair ventricular relaxation-afterload and force-frequency responses and systolic function.

E. Takimoto, K. Bilchick, H. Champion, 2007, American journal of physiology. Heart and circulatory physiology.

The influence of castration on pharmacologically induced penile erection in the cat.

S. Sikka, T. Bivalacqua, H. Champion, 1998, Journal of andrology.

Adrenomedullin enhances cell proliferation and deoxyribonucleic acid synthesis in rat adrenal zona glomerulosa: receptor subtype involved and signaling mechanism.

G. Mazzocchi, G. Nussdorfer, H. Champion, 2000, Endocrinology.

Chronic oral administration of the arginase inhibitor 2(S)-amino-6-boronohexanoic acid (ABH) improves erectile function in aged rats.

A. Burnett, T. Bivalacqua, Xiaopu Liu, 2012, Journal of andrology.

A typical case of atypical dyspnea.

H. Champion, J. Spahr, Eric M. Davis, 2013, Annals of the American Thoracic Society.

Nociceptin Has Vasodilator Activity in the Pulmonary Vascular Bed of the Rat

A. Kaye, B. Nossaman, H. Champion, 1998, Journal of cardiovascular pharmacology and therapeutics.

Differential effects of L-N5-(1-iminoethyl)-ornithine on tone and endothelium-dependent vasodilator responses.

P. Kadowitz, T. Giles, H. Champion, 1997, The American journal of physiology.

Attenuated RhoA/Rho-kinase signaling in penis of transgenic sickle cell mice.

A. Ross, A. Burnett, T. Bivalacqua, 2010, Urology.

Implications of nitric oxide synthase isoforms in the pathophysiology of Peyronie's disease

T. Bivalacqua, H. Champion, W. Hellstrom, 2002, International Journal of Impotence Research.

Towards Systems Biology of Pulmonary Hypertension

Ferhaan Ahmad, N. Kaminski, H. Champion, 2012 .