J. Lok

Longxian Zhang, J. Lok, Zhengqing Yu, 2016, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.

Occurrence of some blood and intestinal parasites in dogs in Curaçao, Netherlands Antilles.

J. Lok, F. Saleh, C. E. Kirkpatrick, 1988, Tropical and geographical medicine.

Advances in the Molecular and Cellular Biology of Strongyloides spp.

J. Lok, Tegegn G. Jaleta, 2019, Current Tropical Medicine Reports.

Transgenesis in the parasitic nematode Strongyloides ratti.

E. Pearce, T. Nolan, M. Viney, 2011, Molecular and biochemical parasitology.

Further studies on the development of onchocerca spp. (Nematoda: Filarioidea) in Nearctic black flies (Diptera: Simuliidae).

R. Pollack, E. Cupp, J. Lok, 1983, The American journal of tropical medicine and hygiene.

Activation of mosquito immunity blocks the development of transmission-stage filarial nematodes

C. Berry, T. Nolan, M. Povelones, 2020, Proceedings of the National Academy of Sciences.

Strongyloides stercoralis and HTLV-1 coinfection in CD34+ cord blood stem cell humanized mice: Alteration of cytokine responses and enhancement of larval growth

T. Manser, A. Rabson, J. Lok, 2021, PLoS neglected tropical diseases.

Extracellular traps are associated with human and mouse neutrophil and macrophage mediated killing of larval Strongyloides stercoralis.

T. Nolan, J. Lok, F. Paumet, 2014, Microbes and infection.

Hc-daf-2 encodes an insulin-like receptor kinase in the barber's pole worm, Haemonchus contortus, and restores partial dauer regulation.

Pasi K. Korhonen, R. Gasser, P. Korhonen, 2014, International journal for parasitology.

Structural and developmental expression of Ss-riok-2, an RIO protein kinase encoding gene of Strongyloides stercoralis

W. Yuan, R. Gasser, Jonathan D. C. Stoltzfus, 2017, Scientific Reports.

Transgenesis and neuronal ablation in parasitic nematodes: revolutionary new tools to dissect host–parasite interactions

D. Artis, J. Lok, 2008, Parasite immunology.

Exploring the role of two interacting phosphoinositide 3-kinases of Haemonchus contortus

Pasi K. Korhonen, R. Gasser, P. Korhonen, 2014, Parasites & Vectors.

Diverse Host-Seeking Behaviors of Skin-Penetrating Nematodes

E. Hallem, Spencer S. Gang, T. Nolan, 2014, PLoS pathogens.

Human and Mouse Macrophages Collaborate with Neutrophils To Kill Larval Strongyloides stercoralis

T. Nolan, J. Lok, D. Abraham, 2013, Infection and Immunity.

The biology of Strongyloides spp.

M. Viney, J. Lok, 2015, WormBook : the online review of C. elegans biology.

Strongyloides spp.

M. Viney, J. Lok, 2007, WormBook : the online review of C. elegans biology.

Development of onchocerca lienalis and O. volvulus from the third to fourth larval stage in vitro.

R. Pollack, J. Donnelly, E. Cupp, 1984, Tropenmedizin und Parasitologie.

Survival and viability of Dirofilaria immitis microfilariae in defined and undefined culture media.

J. Lok, D. Abraham, S. Lauria, 1986, Journal of Parasitology.

First international external quality assessment scheme of nucleic acid amplification tests for the detection of Schistosoma and soil-transmitted helminths, including Strongyloides: A pilot study

J. McCarthy, P. Cools, D. Addiss, 2020, PLoS neglected tropical diseases.

Regulation of Life Cycle Checkpoints and Developmental Activation of Infective Larvae in Strongyloides stercoralis by Dafachronic Acid

S. Kliewer, D. Mangelsdorf, T. Nolan, 2016, PLoS pathogens.

Strongyloides stercoralis age-1: A Potential Regulator of Infective Larval Development in a Parasitic Nematode

T. Nolan, Jonathan D. C. Stoltzfus, J. Lok, 2012, PloS one.

Nucleic acid transfection and transgenesis in parasitic nematodes

J. Lok, 2011, Parasitology.

Microarray-Based Analysis of Differential Gene Expression between Infective and Noninfective Larvae of Strongyloides stercoralis

Sudhir Varma, Timothy G. Myers, T. Myers, 2011, PLoS Neglected Tropical Diseases.

Transgene expression in Strongyloides stercoralis following gonadal microinjection of DNA constructs.

J. Lok, H. Massey, H. C. Massey, 2002, Molecular and biochemical parasitology.

Exploring features and function of Ss-riok-3, an enigmatic kinase gene from Strongyloides stercoralis

W. Yuan, R. Gasser, Jonathan D. C. Stoltzfus, 2014, Parasites & Vectors.

Seasonality of heartworm infection and implications for chemoprophylaxis.

J. Lok, D. Knight, 1998, Clinical techniques in small animal practice.

Dirofilaria Sp.: Taxonomy and Distribution

P. Boreham, J. Lok, R. Atwell, 1988 .

Characterization of the endogenous DAF-12 ligand and its use as an anthelmintic agent in Strongyloides stercoralis

S. Kliewer, D. Mangelsdorf, Jonathan D. C. Stoltzfus, 2021, bioRxiv.

Transcriptional profiles in Strongyloides stercoralis males reveal deviations from the Caenorhabditis sex determination model

T. Nolan, Jonathan D. C. Stoltzfus, Christopher R. Stieha, 2021, Scientific Reports.

Identification of a nuclear receptor/coactivator developmental signaling pathway in the nematode parasite Strongyloides stercoralis

S. Kliewer, D. Mangelsdorf, J. Lok, 2021, Proceedings of the National Academy of Sciences.

Liposome-based transfection enhances RNAi and CRISPR-mediated mutagenesis in non-model nematode systems

A. Pires-daSilva, P. Pathak, J. Lok, 2018, bioRxiv.

Strongyloides stercoralis: cell- and tissue-specific transgene expression and co-transformation with vector constructs incorporating a common multifunctional 3' UTR.

M. Sundaram, T. Nolan, J. Lok, 2008, Experimental parasitology.

Strongyloides stercoralis: a model for translational research on parasitic nematode biology.

J. Lok, 2007, WormBook : the online review of C. elegans biology.

Successful transgenesis of the parasitic nematode Strongyloides stercoralis requires endogenous non-coding control elements.

M. Sundaram, T. Nolan, J. Lok, 2006, International journal for parasitology.

The fork head transcription factor FKTF-1b from Strongyloides stercoralis restores DAF-16 developmental function to mutant Caenorhabditis elegans.

J. Lok, Xinshe Li, M. K. Bhopale, 2006, International journal for parasitology.

Transgenic expression of a T cell epitope in Strongyloides ratti reveals that helminth-specific CD4+ T cells constitute both Th2 and Treg populations

T. Nolan, D. Herbert, J. McLachlan, 2021, PLoS pathogens.

Abnormal patterns of embryogenesis in Dirofilaria immitis treated with ivermectin

J. Lok, T. Harpaz, D. Knight, 1988, Journal of Helminthology.

SEASONAL PREVALENCE OF THIRD-STAGE LARVAE OF DIROFILARIA IMMITIS IN MOSQUITOES FROM FLORIDA AND LOUISIANA

G. Reddy, G. Smith, C. H. Courtney, 2001, The Journal of parasitology.

Cryopreservation of Dirofilaria immitis microfilariae and third-stage larvae

J. Lok, R. Grieve, M. Mika-Grieve, 1983, Journal of Helminthology.

A novel assay to isolate and quantify third-stage Dirofilaria immitis and Brugia malayi larvae emerging from individual Aedes aegypti

T. Nolan, M. Povelones, J. Lok, 2021, Parasites & Vectors.

Activity of an injectable, sustained-release formulation of moxidectin administered prophylactically to mixed-breed dogs to prevent infection with Dirofilaria immitis.

T. Nolan, M. Hendrick, J. Lok, 2001, American journal of veterinary research.

Identification of surrogate rodent hosts for larval Onchocerca lienalis and induction of protective immunity in a model system.

F. Perler, J. Lok, M. Eberhard, 1992, The Journal of parasitology.

Punctate keratitis induced by subconjunctivally injected microfilariae of Onchocerca lienalis.

J. Donnelly, M. Khatami, J. Lok, 1986, Archives of ophthalmology.

Induction of protective immunity against larval Onchocerca volvulus in a mouse model.

J. Lok, M. Trpiš, D. Abraham, 1993, The American journal of tropical medicine and hygiene.

Seasonal timing of heartworm chemoprophylaxis in the United States.

J. Lok, D. Knight, M. Soll, 1995 .

CRISPR/Cas9 Mutagenesis and Expression of Dominant Mutant Transgenes as Functional Genomic Approaches in Parasitic Nematodes

J. Lok, 2019, Front. Genet..

THE SUGAR GLIDER (PETAURUS BREVICEPS): A LABORATORY HOST FOR THE NEMATODE PARASTRONGYLOIDES TRICHOSURI

T. Nolan, W. Grant, J. Lok, 2007, The Journal of parasitology.

Signaling in Parasitic Nematodes: Physicochemical Communication Between Host and Parasite and Endogenous Molecular Transduction Pathways Governing Worm Development and Survival

J. Lok, 2016, Current Clinical Microbiology Reports.

Imaging trematode and nematode parasites

E. Pearce, J. Lok, Edward J. Pearce, 2013, Parasite immunology.

Strongyloides stercoralis: Amphidial neuron pair ASJ triggers significant resumption of development by infective larvae under host-mimicking in vitro conditions.

J. Lok, F. Ashton, G. Schad, 2007, Experimental parasitology.

The 'Nuclear Option' Revisited: Confirmation of Ss-daf-12 Function and Therapeutic Potential in Strongyloides stercoralis and Other Parasitic Nematode Infections.

S. Kliewer, D. Mangelsdorf, J. Lok, 2022, Molecular and biochemical parasitology.

Functional genomic exploration reveals that Ss-RIOK-1 is essential for the development and survival of Strongyloides stercoralis larvae.

W. Yuan, R. Gasser, Min Hu, 2017, International journal for parasitology.

Gastric gnathostomiasis in a cat.

J. Lok, M. Goldschmidt, C E Kirkpatrick, 1987, Journal of the American Veterinary Medical Association.

Evaluation of DNA Extraction Methods on Individual Helminth Egg and Larval Stages for Whole-Genome Sequencing

N. Holroyd, P. Ellis, M. Berriman, 2019, Front. Genet..

Evaluation of DNA Extraction Methods on Individual Helminth Egg and Larval Stages for Whole-Genome Sequencing

N. Holroyd, P. Ellis, M. Berriman, 2019, bioRxiv.

Complete generation rearing of Simulium damnosum s.l. (Diptera: Simuliidae) in the laboratory.

R. Pollack, E. Cupp, J. Lok, 1981, Tropenmedizin und Parasitologie.

In vitro development of third- and fourth-stage larvae of Dirofilaria immitis: comparison of basal culture media, serum levels and possible serum substitutes.

J. Lok, R. Grieve, M. Mika-Grieve, 1984, Acta tropica.

Recovery and viability of Dirofilaria immitis microfilariae.

E. Cupp, J. Lok, R. Grieve, 1984, Acta tropica.

Computed tomographic changes associated with the prepatent and early patent phase of dirofilariasis in an experimentally infected dog.

T. Nolan, J. Lok, C. Reynolds, 2010, Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association.

Entomological studies at an enzootic Venezuelan equine encephalitis virus focus in Guatemala, 1977-1980.

J. Ordonez, E. Cupp, J. Lok, 1986, The American journal of tropical medicine and hygiene.

Fatty Acid Oxidation Is Essential for Egg Production by the Parasitic Flatworm Schistosoma mansoni

Edward J. Pearce, Bart Everts, B. Everts, 2012, PLoS pathogens.

Molecular characterization of the Haemonchus contortus phosphoinositide-dependent protein kinase-1 gene (Hc-pdk-1)

Pasi K. Korhonen, R. Gasser, P. Korhonen, 2016, Parasites & Vectors.

Reconstruction of the insulin-like signalling pathway of Haemonchus contortus

P. Sternberg, Andreas J. Stroehlein, N. Young, 2016, Parasites & Vectors.

Autoantibody induced by experimental Onchocerca infection. Effect of different routes of administration of microfilariae and of treatment with diethylcarbamazine citrate and ivermectin.

D. Hill, J. Donnelly, J. Lok, 1988, Investigative ophthalmology & visual science.

Detection of piggyBac-mediated Transposition by Splinkerette PCR in Transgenic Lines of Strongyloides ratti.

J. Lok, H. Shao, 2014, Bio-protocol.

Cuticular lipids of the imported fire ants, Solenopsis invicta and richteri

G. J. Blomquist, E. Cupp, J. Lok, 1975 .

The Nuclear Receptor DAF-12 Regulates Nutrient Metabolism and Reproductive Growth in Nematodes

S. Kliewer, D. Mangelsdorf, Hao Tang, 2015, PLoS genetics.

Biosynthesis of 3-methylpentacosane in the cockroach Periplaneta americana.

G. J. Blomquist, J. Lok, M. Major, 1975, Biochemical and biophysical research communications.

Two-Stage Isothermal Enzymatic Amplification for Concurrent Multiplex Molecular Detection.

Jinzhao Song, Haim H Bau, Changchun Liu, 2017, Clinical chemistry.

Acceptance of the Bueding and Von Brand Lectureship Award: Functional Genomic Study in Strongyloides and Related Parasitic Nematodes by Transgenesis and CRISPR/CAS9 Mutagenesis

J. Lok, 2018, Journal of Parasitology.

Strongyloides stercoralis daf-2 encodes a divergent ortholog of Caenorhabditis elegans DAF-2.

Jonathan D. C. Stoltzfus, J. Lok, H. Massey, 2013, International journal for parasitology.

Synthetic and naturally occurring retinoids inhibit third- to fourth-stage larval development by Onchocerca lienalis in vitro.

J. Donnelly, J. Lok, B. Sani, 1990, Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ).

Epidemiology of canine heartworm infection.

L. Glickman, J. Lok, R. Grieve, 1983, Epidemiologic reviews.

Structural and functional characterisation of the fork head transcription factor-encoding gene, Hc-daf-16, from the parasitic nematode Haemonchus contortus (Strongylida).

P. Sternberg, R. Gasser, Min Hu, 2010, International journal for parasitology.

Eosinophils act as antigen-presenting cells to induce immunity to Strongyloides stercoralis in mice.

James J. Lee, T. Nolan, J. Lok, 2007, The Journal of infectious diseases.

Studies of reproductive competence in male Dirofilaria immitis treated with milbemycin oxime.

J. Lok, J. Eynard, R. N. Bergman, 1995, Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit.

Macrolide effects on reproductive function in male and female heartworms.

J. Lok, D. Knight, M. Soll, 1995 .

Intestinal threshold of an enzootic strain of Venezuelan encephalitis virus in Culex (Melanoconion) taeniopus mosquitoes and its implications to vector competency and vertebrate amplifying hosts.

J. Ordonez, E. Cupp, J. Lok, 1981, The American journal of tropical medicine and hygiene.

Methylprednisolone acetate induces, and Δ7-dafachronic acid suppresses, Strongyloides stercoralis hyperinfection in NSG mice

S. Kliewer, D. Mangelsdorf, James J. Lee, 2017, Proceedings of the National Academy of Sciences.