Justin A. Spanier

发表

Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes

Jason S. Mitchell, Kristen E. Pauken, Kevin C. Osum, 2018, Scientific Reports.

PD-1 pathway-mediated regulation of islet-specific CD4+ T cell subsets in autoimmune diabetes

Kristen E. Pauken, Tijana Martinov, Justin A. Spanier, 2016, Immunoendocrinology.

Estrogen Controls Vitamin D3-Mediated Resistance to Experimental Autoimmune Encephalomyelitis by Controlling Vitamin D3 Metabolism and Receptor Expression1

Justin A. Spanier, K. Spach, F. Nashold, 2009, The Journal of Immunology.

Cutting Edge: Dual TCRα Expression Poses an Autoimmune Hazard by Limiting Regulatory T Cell Generation

K. Hogquist, Tijana Martinov, Justin A. Spanier, 2017, The Journal of Immunology.

Regulatory T Cell Generation an Autoimmune Hazard by Limiting Expression Poses α Cutting Edge : Dual TCR

Tijana Martinov, Justin A. Spanier, B. Fife, 2017 .

1,25‐Dihydroxyvitamin D3 acts directly on the T lymphocyte vitamin D receptor to inhibit experimental autoimmune encephalomyelitis

C. Mayne, Justin A. Spanier, C. Hayes, 2011, European journal of immunology.

Vitamin D and estrogen synergy in Vdr-expressing CD4+ T cells is essential to induce Helios+FoxP3+ T cells and prevent autoimmune demyelinating disease

C. Mayne, C. Nelson, Justin A. Spanier, 2015, Journal of Neuroimmunology.

Cutting Edge: Type 1 Diabetes Occurs despite Robust Anergy among Endogenous Insulin-Specific CD4 T Cells in NOD Mice

Jonathan L. Linehan, M. Jenkins, D. Mueller, 2013, The Journal of Immunology.

Vitamin D3 alters microglia immune activation by an IL-10 dependent SOCS3 mechanism

Mandy Boontanrart, Justin A. Spanier, C. Hayes, 2016, Journal of Neuroimmunology.

1,25-Dihydroxyvitamin D3 increases the methionine cycle, CD4+ T cell DNA methylation and Helios+Foxp3+ T regulatory cells to reverse autoimmune neurodegenerative disease

Shane L. Hubler, C. Nelson, Justin A. Spanier, 2018, Journal of Neuroimmunology.

Thymic regulatory T cells arise via two distinct developmental programs

Mark S. Anderson, M. Farrar, A. Marson, 2019, Nature Immunology.

Efficient generation of monoclonal antibodies against peptide in the context of MHCII using magnetic enrichment

Dmitri I. Kotov, M. Jenkins, J. McLachlan, 2016, Nature Communications.

Cutting Edge: Identification of Autoreactive CD4+ and CD8+ T Cell Subsets Resistant to PD-1 Pathway Blockade

M. Jenkins, J. Schenkel, Kristen E. Pauken, 2015, The Journal of Immunology.

PD-1 Pathway Blockade T Cell Subsets Resistant to + and CD8 + CD4Cutting Edge: Identification of Autoreactive

J. Schenkel, Kristen E. Pauken, V. Vezys, 2015 .

Insulin-Specific CD4 T Cells in NOD Mice despite Robust Anergy among Endogenous Cutting Edge: Type 1 Diabetes Occurs

Jonathan L. Linehan, M. Jenkins, D. Mueller, 2013 .

Programmed Death-1 Restrains the Germinal Center in Type 1 Diabetes

Jason S. Mitchell, K. Hogquist, N. Sahli, 2019, The Journal of Immunology.

Programmed Death-1 Culls Peripheral Accumulation of High-Affinity Autoreactive CD4 T Cells to Protect against Autoimmunity.

Tony T. Jiang, S. Way, Justin A. Spanier, 2016, Cell reports.

The Ifng Gene Is Essential for Vdr Gene Expression and Vitamin D3-Mediated Reduction of the Pathogenic T Cell Burden in the Central Nervous System in Experimental Autoimmune Encephalomyelitis, a Multiple Sclerosis Model

Justin A. Spanier, F. Nashold, C. Hayes, 2012, The Journal of Immunology.

Sclerosis Model Autoimmune Encephalomyelitis , a Multiple the Central Nervous System in Experimental inReduction of the Pathogenic T Cell Burden-Mediated 3 Expression and Vitamin D Gene Vdr Gene Is Essential for Ifng The

Justin A. Spanier, F. Nashold, C. Hayes, 2012 .

T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity.

Dmitri I. Kotov, M. Jenkins, J. Moon, 2015, Immunity.

Vitamin D3-mediated resistance to a multiple sclerosis model disease depends on myeloid cell 1,25-dihydroxyvitamin D3 synthesis and correlates with increased CD4+ T cell CTLA-4 expression

C. Nelson, Justin A. Spanier, Corinne E. Praska, 2019, Journal of Neuroimmunology.

Multiple Sclerosis in Women: Vitamin D and Estrogen Synergy for Autoimmune T-Cell Regulation and Demyelinating Disease Prevention

Justin A. Spanier, C. Hayes, 2017 .

Vitamin D and Autoimmune Disease

C. Nelson, Justin A. Spanier, C. Hayes, 2012 .

Development of canine PD-1/PD-L1 specific monoclonal antibodies and amplification of canine T cell function

R. Rebhun, R. Sciammas, P. Moore, 2020, PloS one.

Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes

Jason S. Mitchell, Kristen E. Pauken, Kevin C. Osum, 2018, Scientific Reports.

Increased Effector Memory Insulin-Specific CD4+ T Cells Correlate With Insulin Autoantibodies in Patients With Recent-Onset Type 1 Diabetes

M. Jenkins, A. Moran, B. Blazar, 2017, Diabetes.

Editorial: Fresh Ideas, Foundational Experiments: Immunology and Diabetes

Justin A. Spanier, B. Fife, M. Horwitz, 2019, Frontiers in Endocrinology.

Insulin B peptide-MHC class II-specific chimeric antigen receptor-Tregs prevent autoimmune diabetes

Jason S. Mitchell, M. Levings, P. Orban, 2023, bioRxiv.

Tregs with an MHC class II peptide–specific chimeric antigen receptor prevent autoimmune diabetes in mice

M. Levings, Justin A. Spanier, B. Fife, 2023 .

Tregs with an MHC class II peptide–specific chimeric antigen receptor prevent autoimmune diabetes in mice

Jason S. Mitchell, M. Levings, P. Orban, 2023, The Journal of clinical investigation.

Vitamin D3 alters microglia immune activation by an IL-10 dependent SOCS3 mechanism

Mandy Boontanrart, Justin A. Spanier, C. Hayes, 2016, Journal of Neuroimmunology.

Chapter 95 – Vitamin D and Multiple Sclerosis

Justin A. Spanier, F. Nashold, Colleen E. Hayes, 2011 .

CD4+ T cells reactive to a hybrid peptide from insulin-chromogranin A adopt a distinct effector fate and are pathogenic in autoimmune diabetes.

T. Kaisho, Justin A. Spanier, B. Fife, 2024, Immunity.