P. Rennert

发表

CTLA4 mediates antigen-specific apoptosis of human T cells.

J. Gribben, G. Freeman, G. Gray, 1995, Proceedings of the National Academy of Sciences of the United States of America.

A Soluble Form of B Cell Maturation Antigen, a Receptor for the Tumor Necrosis Factor Family Member April, Inhibits Tumor Cell Growth

J. Tschopp, C. Ambrose, P. Schneider, 2000, The Journal of experimental medicine.

Novel roles for TIM-1 in immunity and infection.

P. Rennert, 2011, Immunology letters.

Semaphorin 7A initiates T-cell-mediated inflammatory responses through α1β1 integrin

A. Kolodkin, J. Takagi, Kazuhiro Suzuki, 2007, Nature.

Surface lymphotoxin alpha/beta complex is required for the development of peripheral lymphoid organs

F. Mackay, J. Browning, P. Rennert, 1996, The Journal of experimental medicine.

Surface Lymphotoxin Tx/~ Complex Is Required for the Development of Peripheral Lymphoid Organs

F. Mackay, J. Browning, P. Rennert, 1996 .

Lymph Node Genesis Is Induced by Signaling through the Lymphotoxin β Receptor

F. Mackay, J. Browning, P. Rennert, 1998 .

Anti-CD19 CAR T Cells That Secrete a Biparatopic Anti-CLEC12A Bridging Protein Have Potent Activity Against Highly Aggressive Acute Myeloid Leukemia In Vitro and In Vivo

C. Ambrose, Lan Wu, Fay J. Dufort, 2021, Molecular Cancer Therapeutics.

Mutations in the principal neutralization determinant of human immunodeficiency virus type 1 affect syncytium formation, virus infectivity, growth kinetics, and neutralization

M. Hammarskjöld, P. Rennert, R. Grimaila, 1992, Journal of virology.

Developing lymph nodes collect CD4+CD3- LTbeta+ cells that can differentiate to APC, NK cells, and follicular cells but not T or B cells.

I. Weissman, P. Rennert, R. Mebius, 1997, Immunity.

Characterizing Functional Domains for TIM-Mediated Enveloped Virus Entry

L. Albritton, Sven Moller-Tank, P. Rennert, 2014, Journal of Virology.

Novel Immunotherapeutic Approaches to the Treatment of Cancer

P. Rennert, 2016, Springer International Publishing.

CAR-T Engager proteins optimize anti-CD19 CAR-T cell therapies for lymphoma

C. Ambrose, Lan Wu, P. Rennert, 2022, bioRxiv.

The New Frontier of Antibody Drug Conjugates: Targets, Biology, Chemistry, Payloads

P. Rennert, C. Thanos, 2016 .

Elimination of Colonic Patches with Lymphotoxin β Receptor-Ig Prevents Th2 Cell-Type Colitis1

J. Mcghee, H. Kiyono, J. Browning, 2001, The Journal of Immunology.

Brief Definitive Report Essential Role of Nuclear Factor (nf)-␬ B–inducing Kinase and Inhibitor of ␬ B (i ␬ B) Kinase ␣ in Nf-␬ B Activation through Lymphotoxin ␤ Receptor, but Not through Tumor Necrosis Factor Receptor I

S. Akira, T. Kaisho, K. Takeda, 2022 .

Meeting on Signalling Networks in Immunity and Inflammation

M. Karin, D. Rawlings, C. Martínez-A, 2006 .

Essential Role of Nuclear Factor (NF)- k B–inducing Kinase and Inhibitor of k B (I k B) Kinase a in NF- k B Activation through Lymphotoxin b Receptor, but Not through Tumor Necrosis Factor Receptor I

S. Akira, T. Kaisho, K. Takeda, 2001 .

The IgV domain of human B7-2 (CD86) is sufficient to co-stimulate T lymphocytes and induce cytokine secretion.

G. Freeman, B. Levine, C. June, 1997, International immunology.

Regulation of inflammation by collagen-binding integrins alpha1beta1 and alpha2beta1 in models of hypersensitivity and arthritis.

V. Koteliansky, A. D. de Fougerolles, A. Sprague, 2000, The Journal of clinical investigation.

Nerve growth factor mRNA in brain: localization by in situ hybridization.

P. Rennert, G. Heinrich, 1986, Biochemical and biophysical research communications.

Role of Gut-Associated Lymphoreticular Tissues in Antigen-Specific Intestinal IgA Immunity1

J. Mcghee, H. Kiyono, Masafumi Yamamoto, 2004, The Journal of Immunology.

ImmunityTissues in Antigen-Specific Intestinal IgA Role of Gut-Associated Lymphoreticular

J. Mcghee, H. Kiyono, Masafumi Yamamoto, 2004 .

Cutting Edge: Langerin+ Dendritic Cells in the Mesenteric Lymph Node Set the Stage for Skin and Gut Immune System Cross-Talk1

H. Kiyono, B. Malissen, O. Igarashi, 2008, The Journal of Immunology.

Hapten-induced Colitis Is Associated with Colonic Patch Hypertrophy and T Helper Cell 2–Type Responses

J. Mcghee, H. Kiyono, P. Rennert, 1999, The Journal of experimental medicine.

Antagonism of TIM-1 blocks the development of disease in a humanized mouse model of allergic asthma.

Y. Hsu, H. Renz, A. Kılıç, 2010, The Journal of clinical investigation.

Bimodal regulation of T cell-mediated immune responses by TIM-4.

Kazuhiro Suzuki, T. Yasui, H. Kikutani, 2008, International immunology.

CD8α–11b+ dendritic cells but not CD8α+ dendritic cells mediate cross-tolerance toward intestinal antigens

Jae-Hoon Chang, P. Rennert, Yeonseok Chung, 2005 .

Cortisone, testosterone, and aldosterone reduce levels of nerve growth factor messenger ribonucleic acid in L-929 fibroblasts.

R. A. Murphy, P. Rennert, K. Siminoski, 1987, Endocrinology.

Cholangiocyte expression of alpha2beta1-integrin confers susceptibility to rotavirus-induced experimental biliary atresia.

P. Weinreb, R. Ward, G. Tiao, 2008, American journal of physiology. Gastrointestinal and liver physiology.

Cholangiocyte expression of 2 1-integrin confers susceptibility to rotavirus-induced experimental biliary atresia

P. Weinreb, G. Tiao, Mubeen A. Jafri, 2008 .

Control of T helper 2 cell function and allergic airway inflammation by PKCzeta.

Pilar Martín, C. Martínez-A, Á. Zaballos, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin.

A. Kolodkin, J. Takagi, Kazuhiro Suzuki, 2007, Nature.

TIM-family proteins inhibit HIV-1 release

Marc C. Johnson, E. Freed, P. Rennert, 2014, Proceedings of the National Academy of Sciences.

PKCζ at the crossroad of NF-κB and Jak1/Stat6 signaling pathways

M. Diaz-Meco, J. Moscat, P. Rennert, 2006, Cell Death and Differentiation.

Epitope-Dependent Effect of Anti-Murine TIM-1 Monoclonal Antibodies on T Cell Activity and Lung Immune Responses

Sambasiva P Rao, M. Scott, M. Zafari, 2007, The Journal of Immunology.

Lymph node genesis is induced by signaling through the lymphotoxin beta receptor.

F. Mackay, J. Browning, P. Rennert, 1998, Immunity.

Genomic organization of the gene coding for the costimulatory human B-lymphocyte antigen B7-2 (CD86)

A. Sharpe, G. Gray, Sophia S. Wang, 2004, Immunogenetics.

Initiation of NALT organogenesis is independent of the IL-7R, LTbetaR, and NIK signaling pathways but requires the Id2 gene and CD3(-)CD4(+)CD45(+) cells.

S. Fukuyama, H. Kiyono, Masafumi Yamamoto, 2002, Immunity.

Regulation of Peripheral Lymph Node Genesis by the Tumor Necrosis Factor Family Member Trance

Steffen Jung, Dongku Kim, Yongwon Choi, 2000, The Journal of experimental medicine.

Essential Role of Lymph Nodes in Contact Hypersensitivity Revealed in Lymphotoxin-α–Deficient Mice

R. Flavell, D. Chaplin, J. Browning, 2001, The Journal of experimental medicine.

Essential Role of Lymph Nodes in Contact Hypersensitivity Revealed in Lymphotoxin- (cid:2) –deﬁcient Mice

R. Flavell, D. Chaplin, J. Browning, 2001 .

Role of zeta PKC in B-cell signaling and function.

Pilar Martín, A. Durán, M. Diaz-Meco, 2002, The EMBO journal.

Gene expression profiling of rubella virus infected primary endothelial cells of fetal and adult origin

A. Mankertz, M. Bauer, P. Rennert, 2016, Virology Journal.

NF‐κB activation by protein kinase C isoforms and B‐cell function

J. Moscat, M. Diaz-Meco, P. Rennert, 2003 .

review NF-κB activation by protein kinase C isoforms and B-cell function

M. Diaz-Meco, J. Moscat, P. Rennert, 2003 .

Characterization of lymphotoxin-alpha beta complexes on the surface of mouse lymphocytes.

C. Ambrose, C. Benjamin, P. Lawton, 1997, Journal of immunology.

PKCzeta at the crossroad of NF-kappaB and Jak1/Stat6 signaling pathways.

M. Diaz-Meco, J. Moscat, P. Rennert, 2006, Cell death and differentiation.

T Cell, Ig Domain, Mucin Domain-2 Gene-Deficient Mice Reveal a Novel Mechanism for the Regulation of Th2 Immune Responses and Airway Inflammation1

J. Bonventre, L. Pablo, P. Mccoon, 2006, The Journal of Immunology.

Inflammation Immune Responses and Airway Mechanism for the Regulation of Th 2 Gene-Deficient Mice Reveal a Novel T Cell , Ig Domain , Mucin Domain-2 and

L. Pablo, P. Mccoon, P. Rennert, 2006 .

Regulation of inflammation by collagen-binding integrins α1β1 and α2β1 in models of hypersensitivity and arthritis

V. Koteliansky, A. Sprague, A. D. Fougerolles, 2000 .

Peyer's patches are required for oral tolerance to proteins

J. Mcghee, H. Kiyono, Masafumi Yamamoto, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Perturbation of the carboxy terminus of HIV-1 Rev affects multimerization on the Rev responsive element.

M. Auer, G. Farrington, J. Barry, 1993, Biochemistry.

Fyn binds to and phosphorylates T cell immunoglobulin and mucin domain-1 (Tim-1).

J. Colgan, P. Rothman, M. Curtiss, 2011, Molecular immunology.

Treatment of autoimmune hyperthyroidism in a murine model of Graves' disease with tumor necrosis factor-family ligand inhibitors suggests a key role for B cell activating factor in disease pathology.

S. Kalled, J. Banga, P. Rennert, 2006, Endocrinology.

Glyco-engineered HEK 293-F cell lines for the production of therapeutic glycoproteins with human N-glycosylation and improved pharmacokinetics.

P. Wiedemann, Ruth Popa-Wagner, A. Seifried, 2021, Glycobiology.

BAFF AND APRIL: a tutorial on B cell survival.

P. Schneider, F. Mackay, J. Browning, 2003, Annual review of immunology.

Combination cancer immunotherapy and new immunomodulatory targets

G. Freeman, P. Rennert, K. Mahoney, 2015, Nature Reviews Drug Discovery.

Anti-CD19 CAR T cells potently redirected to kill solid tumor cells

C. Ambrose, Lan Wu, Fay J. Dufort, 2020, bioRxiv.

CD8alpha-11b+ dendritic cells but not CD8alpha+ dendritic cells mediate cross-tolerance toward intestinal antigens.

Jae-Hoon Chang, P. Rennert, Yeonseok Chung, 2005, Blood.

Intestinal villous M cells: an antigen entry site in the mucosal epithelium.

C. Sasakawa, H. Kiyono, Masafumi Yamamoto, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Mesenteric lymph nodes are critical for the induction of high‐dose oral tolerance in the absence of Peyer's patches

H. Weiner, A. Fontana, T. Kucharzik, 2002, European journal of immunology.

An essential function for the nuclear receptor RORγt in the generation of fetal lymphoid tissue inducer cells

Yongwon Choi, Gérard Eberl, D. Littman, 2004, Nature Immunology.

Molecular Basis for Hematopoietic/Mesenchymal Interaction during Initiation of Peyer's Patch Organogenesis

Koichi Ikuta, Tsutomu Chiba, Shin-Ichi Nishikawa, 2001, The Journal of experimental medicine.

Involvement of distinct cellular compartments in the abnormal lymphoid organogenesis in lymphotoxin-alpha-deficient mice and alymphoplasia (aly) mice defined by the chimeric analysis.

M. Okabe, M. Matsumoto, S. Fujita, 1999, Journal of immunology.

Prenatal Blockage of Lymphotoxin β Receptor and TNF Receptor p55 Signaling Cascade Resulted in the Acceleration of Tissue Genesis for Isolated Lymphoid Follicles in the Large Intestine1

H. Kiyono, Masafumi Yamamoto, Sun-Young Chang, 2005, The Journal of Immunology.

Induction of oral tolerance to cellular immune responses in the absence of Peyer's patches

H. Weiner, R. Flavell, A. Fontana, 2001, European journal of immunology.

Selective disruption of lymphotoxin ligands reveals a novel set of mucosal lymph nodes and unique effects on lymph node cellular organization.

J. Browning, P. Rennert, P. Hochman, 1997, International immunology.

Biochemical Systematics of Peromyscus boylii II. Chromosomally Variable Populations from Eastern and Southern Mexico

C. W. Kilpatrick, P. Rennert, 1987 .

Targeted Disruption of the ζPKC Gene Results in the Impairment of the NF-κB Pathway

Juan F. García, Pilar Martín, A. Durán, 2001 .

Novel Immunomodulatory Pathways in the Immunoglobulin Superfamily

P. Rennert, 2016 .

Requirement for the NF-κB Family Member RelA in the Development of Secondary Lymphoid Organs

N. Hacohen, D. Baltimore, R. Hynes, 2002, The Journal of experimental medicine.

Gene Profiling in Atherosclerosis Reveals a Key Role for Small Inducible Cytokines: Validation Using a Novel Monocyte Chemoattractant Protein Monoclonal Antibody

C. Mackay, C. Evelo, L. Beckers, 2005, Circulation.

Validation Using a Novel Monocyte Chemoattractant Protein Monoclonal Antibody Gene Profiling in Atherosclerosis Reveals a Key Role for Small Inducible Cytokines

C. Evelo, L. Beckers, E. Lutgens, 2005 .

Fine epitope mapping of the CD19 extracellular domain promotes design.

Justin R. Klesmith, Lan Wu, P. Rennert, 2019, Biochemistry.

TIM-1 glycoprotein binds the adhesion receptor P-selectin and mediates T cell trafficking during inflammation and autoimmunity.

V. Kuchroo, S. Xiao, B. Rossi, 2014, Immunity.

Identification of proteoglycans as the APRIL-specific binding partners

J. Tschopp, P. Schneider, A. Tardivel, 2005, The Journal of experimental medicine.

Biochemical characterization of binding of multiple HIV-1 Rev monomeric proteins to the Rev responsive element.

M. Auer, P. Rennert, J. Rusche, 1993, Biochemistry.

Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway.

A. Durán, M. Diaz-Meco, J. Moscat, 2001, Molecular cell.

T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus

R. Davey, D. Meyerholz, J. Chiorini, 2011, Proceedings of the National Academy of Sciences.

BAFF AND APRIL: AT utorial on BC ell Survival

P. Schneider, F. Mackay, J. Browning, 2003 .

Alternate Mucosal Immune System: Organized Peyer’s Patches Are Not Required for IgA Responses in the Gastrointestinal Tract1

J. Mcghee, H. Kiyono, Masafumi Yamamoto, 2000, The Journal of Immunology.

Animal Model Induction of Colitis in Mice Deficient of Peyer’s Patches and Mesenteric Lymph Nodes Is Associated with Increased Disease Severity and Formation of Colonic Lymphoid Patches

H. Weiner, H. Herbst, A. Fontana, 2002 .

B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4.

J. Gribben, G. Freeman, G. Gray, 1995, Immunity.

Mumps Virus SH Protein Inhibits NF-κB Activation by Interacting with Tumor Necrosis Factor Receptor 1, Interleukin-1 Receptor 1, and Toll-Like Receptor 3 Complexes

A. Mankertz, T. Finsterbusch, S. Franz, 2017, Journal of Virology.

Mumps Virus SH protein inhibits NF-κB activation by interacting with TNFR 1 , IL-1 R 1 , and 1 TLR 3 complexes 2 3

Nicole, A. Mankertz, T. Finsterbusch, 2017 .

Targeted disruption of Traf5 gene causes defects in CD40- and CD27-mediated lymphocyte activation.

C. Ware, M. Matsumoto, S. Santee, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Retargeting CD19 CAR T cells via engineered CD19-fusion proteins.

Justin R. Klesmith, C. Ambrose, Lan Wu, 2019, Molecular pharmaceutics.

A CD19-Anti-ErbB2 scFv Engager Protein Enables CD19-Specific CAR T Cells to Eradicate ErbB2+ Solid Cancer

C. Ambrose, H. Abken, P. Rennert, 2023, Cells.

Regulation of inflammation by collagen-binding integrins a 1 b 1 and a 2 b 1 in models of hypersensitivity and arthritis

V. Koteliansky, A. Sprague, A. D. Fougerolles, 2018 .

Role of the Phosphatidylserine Receptor TIM-1 in Enveloped-Virus Entry

R. Davey, Sven Moller-Tank, P. Rennert, 2013, Journal of Virology.

Defining critical residues in the epitope for a HIV-neutralizing monoclonal antibody using phage display and peptide array technologies.

T. Cradick, G. Gray, P. Rennert, 1993, Gene.

Human TIM-1 Associates with the TCR Complex and Up-Regulates T Cell Activation Signals

M. Scott, P. Rennert, Lauri L. Binné, 2007, The Journal of Immunology.

NF-kappaB activation by protein kinase C isoforms and B-cell function.

M. Diaz-Meco, J. Moscat, P. Rennert, 2003, EMBO reports.

Role of ζPKC in B‐cell signaling and function

Pilar Martín, A. Durán, M. Diaz-Meco, 2002 .

The Cellular Localization of Preprotachykinin, Preproenkephalin A and Beta Prepronerve Growth Factor mRNA

M. Goedert, P. Rennert, G. Heinrich, 1986 .

Inflammatory responses following Chlamydia pneumoniae infection of glial cells

I. Pronk, P. Rennert, V. Bailly, 2007, The European journal of neuroscience.

Complex and UpRegulates T Cell Activation Human TIM-1 Associates with the TCR

M. Scott, P. Rennert, Lauri L. Binné, 2007 .

Characterizing Functional Domains for TIM-Mediated Enveloped Virus Entry

L. Albritton, Sven Moller-Tank, P. Rennert, 2014, Journal of Virology.

Antagonism of TIM-1 blocks the development of disease in a humanized mouse model of allergic asthma.

Y. Hsu, H. Renz, A. Kılıç, 2010, The Journal of clinical investigation.

SIVmac expressing hybrid envelope proteins containing HIV-1 V3 and/or C4 sequences is not competent for replication.

R. Desrosiers, F. Kirchhoff, P. Rennert, 1994, AIDS research and human retroviruses.