Songmao Zheng

发表

Utility of free and total target measurements as target engagement and efficacy biomarkers in biotherapeutic development—Opportunities and challenges

Songmao Zheng, Thomas McIntosh, Weirong Wang, 2015, Journal of clinical pharmacology.

Development of a Population Pharmacokinetic Model Characterizing the Tissue Distribution of Azithromycin in Healthy Subjects

M. Zeitlinger, Songmao Zheng, P. Matzneller, 2014, Antimicrobial Agents and Chemotherapy.

Therapeutic antibody development—Remington chapter

Brian J. Geist, Songmao Zheng, Yan Xu, 2021 .

Rapid Purification of Human Bispecific Antibodies via Selective Modulation of Protein A Binding

M. Chiu, Songmao Zheng, S. Tam, 2017, Scientific Reports.

A minimal physiologically based pharmacokinetic model to characterize colon TNF suppression and treatment effects of an anti-TNF monoclonal antibody in a mouse inflammatory bowel disease model

Brian J. Geist, Honghui Zhou, Songmao Zheng, 2020, mAbs.

The Impact of CYP3A5 Variation and Pregnancy on the Metabolic Disposition of Calcineurin Inhibitors

Songmao Zheng, 2012 .

Characterization of concurrent target suppression by JNJ-61178104, a bispecific antibody against human tumor necrosis factor and interleukin-17A

Brian J. Geist, Songmao Zheng, Weirong Wang, 2020, mAbs.

Impact of Diseases, Comorbidity, and Target Physiology on ADME, PK, and PK/PD of Therapeutic Biologics

Honghui Zhou, Songmao Zheng, Weirong Wang, 2015 .

Design, synthesis and preclinical evaluation of bio-conjugated amylinomimetic peptides as long-acting amylin receptor agonists.

R. Patch, O. Libiger, S. Edavettal, 2022, European journal of medicinal chemistry.

Amino acids are sensitive glucagon receptor‐specific biomarkers for glucagon‐like peptide‐1 receptor/glucagon receptor dual agonists

T. Kirchner, Songmao Zheng, Wenying Jian, 2020, Diabetes, obesity & metabolism.

Changing the drug development and therapeutic paradigm with biologic drug combinations and bispecifics: How to choose between these two approaches?

Yow-Ming C Wang, Songmao Zheng, R. Prell, 2022, Clinical and translational science.

Evaluation of changes in oral drug absorption in preterm and term neonates for Biopharmaceutics Classification System (BCS) class I and II compounds.

Songmao Zheng, S. Willmann, S. Schmidt, 2016, British journal of clinical pharmacology.

Toward Progress in Quantitative Translational Medicine: A Call to Action

K. Venkatakrishnan, S. Visser, Songmao Zheng, 2019, Clinical pharmacology and therapeutics.

Interpreting Tacrolimus Concentrations During Pregnancy and Postpartum

M. Hebert, D. Shen, Songmao Zheng, 2013, Transplantation.

Model‐Based Cellular Kinetic Analysis of Chimeric Antigen Receptor‐T Cells in Humans

Aman P. Singh, Yanguang Cao, Songmao Zheng, 2020, medRxiv.

Cross-arm binding efficiency of an EGFR x c-Met bispecific antibody

M. Chiu, Honghui Zhou, Songmao Zheng, 2016, mAbs.

Tacrolimus placental transfer at delivery and neonatal exposure through breast milk.

M. Hebert, D. Shen, Songmao Zheng, 2013, British journal of clinical pharmacology.

Pharmacokinetics of Tacrolimus During Pregnancy

M. Hebert, D. Shen, Songmao Zheng, 2012, Therapeutic drug monitoring.

Simultaneous measurement of plasma vitamin D(3) metabolites, including 4β,25-dihydroxyvitamin D(3), using liquid chromatography-tandem mass spectrometry.

Kenneth E Thummel, M. Hebert, Yvonne S. Lin, 2011, Analytical biochemistry.

Modulation of protein A binding allows single-step purification of mouse bispecific antibodies that retain FcRn binding

G. Gilliland, M. Chiu, Songmao Zheng, 2017, mAbs.

A Long-Acting PYY3-36 Analog Mediates Robust Anorectic Efficacy with Minimal Emesis in Nonhuman Primates.

M. Erion, R. Swanson, Rebecca R. Pick, 2019, Cell metabolism.

Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections.

Jinquan Luo, T. Malia, P. Buckley, 2023, Cell host & microbe.

A long‐acting GDF15 analog causes robust, sustained weight loss and reduction of food intake in an obese nonhuman primate model

Brian J. Geist, A. Nawrocki, Songmao Zheng, 2022, bioRxiv.

CYP3A5 Gene Variation Influences Cyclosporine A Metabolite Formation and Renal Cyclosporine Disposition

M. Hebert, Yvonne S. Lin, D. Shen, 2013, Transplantation.

Abstract 2868: ADG206, an anti-CD137 agonistic POWERbody࣪ with tailor-made efficacy and safety profiles by strong crosslinking and tumor selective activation for single and combinational cancer immunotherapy

Jiangchun Xu, Songmao Zheng, Guizhong Liu, 2022, Cancer Research.

The quest for balance between capturing data and model complexity: A quantitative clinical pharmacology approach applied to monoclonal antibodies

L. Peletier, V. D. Sharma, Honghui Zhou, 2023, CPT: pharmacometrics & systems pharmacology.

How resilient were we in 2021? Results of a LinkedIn Survey including biomedical and pharmaceutical professionals using the Benatti Resiliency Model

K. Venkatakrishnan, Songmao Zheng, Beth Kennedy, 2022, Clinical and translational science.

Diversity in Clinical Pharmacology: A Call to Action

Songmao Zheng, P. Jayachandran, A. Oni‐Orisan, 2023, Clinical pharmacology and therapeutics.