J. Kovarik

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Targeting the CXCR4–CXCL12 Axis Mobilizes Autologous Hematopoietic Stem Cells and Prolongs Islet Allograft Survival via Programmed Death Ligand 1

S. Rodig, R. Abdi, M. Jurewicz, 2011, The Journal of Immunology.

Longitudinal assessment of a P‐glycoprotein–mediated drug interaction of valspodar on digoxin

J. Kovarik, J. Kovarik, M. Guerret, 1999, Clinical pharmacology and therapeutics.

Requirement of Mucosa‐Associated Lymphoid Tissue Lymphoma Translocation Protein 1 Protease Activity for Fcγ Receptor–Induced Arthritis, but Not Fcγ Receptor–Mediated Platelet Elimination, in Mice

T. Junt, E. Degl'innocenti, G. Wieczorek, 2020 .

Disposition and immunodynamics of basiliximab in liver allograft recipients

J. Kovarik, T. Breidenbach, B. Nashan, 1998, Clinical pharmacology and therapeutics.

The T‐cell fingerprint of MALT1 paracaspase revealed by selective inhibition

G. Bold, M. Renatus, J. Kovarik, 2018, Immunology and cell biology.

Pharmacokinetics of Dexamethasone and Valspodar, a P‐glycoprotein (mdr1) Modulator: Implications for Coadministration

J. Kovarik, E. Mueller, C. Gerbeau, 1998, Pharmacotherapy.

Generation of adult‐like antibody avidity profiles after early‐life immunization with protein vaccines

P. Lambert, G. Giudice, C. Siegrist, 2002, European journal of immunology.

The critical role of kinase activity of interleukin-1 receptor-associated kinase 4 in animal models of joint inflammation.

H. Gram, J. Kovarik, C. Burkhart, 2009, Arthritis and rheumatism.

This information is current as via Programmed Death Ligand 1 Cells and Prolongs Islet Allograft Survival Mobilizes Autologous Hematopoietic Stem CXCL12 Axis - Targeting the CXCR4

S. Rodig, R. Abdi, M. Jurewicz, 2012 .

Special ergolines efficiently inhibit the chemokine receptor CXCR3 in blood.

M. Streiff, G. Thoma, J. Kovarik, 2011, Bioorganic & medicinal chemistry letters.

CD4-independent protective cytotoxic T cells induced in early life by a non-replicative delivery system based on virus-like particles.

C. Leclerc, P. Lambert, C. Siegrist, 2003, Virology.

The Use of DNA Vaccines for Neonatal/Early Life Childhood Immunization

C. Siegrist, J. Kovarik, X. Martinez, 2003 .

CD 4-Independent Protective Cytotoxic T Cells Induced in Early Life by a Non-Replicative Delivery System Based on Virus-like Particles

C. Leclerc, P. Lambert, C. Siegrist, 2003 .

From Immunosuppression to Immunomodulation: Current Principles and Future Strategies

J. Kovarik, 2013, Pathobiology.

Limitations of in vivo IL-12 supplementation strategies to induce Th1 early life responses to model viral and bacterial vaccine antigens.

T. Kipps, T. Wild, P. Lambert, 2000, Virology.

Combining DNA and protein vaccines for early life immunization against respiratory syncytial virus in mice

M. Klein, P. Lambert, C. Siegrist, 1999, European journal of immunology.

CpG oligodeoxynucleotides can circumvent the Th2 polarization of neonatal responses to vaccines but may fail to fully redirect Th2 responses established by neonatal priming.

P. Lambert, C. Siegrist, J. Kovarik, 1999, Journal of immunology.

Therapeutic activity of multiple common γ-chain cytokine inhibition in acute and chronic GVHD.

A. Schmitt-Graeff, B. Blazar, J. Kovarik, 2015, Blood.

Delayed and deficient establishment of the long‐term bone marrow plasma cell pool during early life

P. Lambert, C. Siegrist, J. Kovarik, 2001, European journal of immunology.

Adjuvant effects of CpG oligodeoxynucleotides on responses against T‐independent type 2 antigens

P. Lambert, C. Siegrist, J. Kovarik, 2001, Immunology.

Induction of neonatal TH1 and CTL responses by live viral vaccines: a role for replication patterns within antigen presenting cells?

P. Lambert, C. Siegrist, J. Kovarik, 1998, Vaccine.

Immunity in early life.

C. Siegrist, J. Kovarik, 1998, Immunology today.

Optimization of vaccine responses in early life: The role of delivery systems and immunomodulators

C. Siegrist, J. Kovarik, 1998, Immunology and cell biology.

Cyclophosphamide, but not CTLA4Ig, prolongs survival of fetal pig islet grafts in anti‐T cell monoclonal antibody‐treated NOD mice

J. Kovarik, M. Koulmanda, T. Mandel, 1998, Xenotransplantation.

Optimizing the Absorption of Valspodar, a P‐glycoprotein Modulator, Part I: Selecting an Oral Formulation and Exploring its Clinical Pharmacokinetics/Dynamics

J. Kovarik, E. Mueller, P. Lücker, 1997, Journal of clinical pharmacology.

Determinants of infant responses to vaccines in presence of maternal antibodies.

P. Lambert, C. Siegrist, J. Kovarik, 1998, Vaccine.

Orally bioavailable isothioureas block function of the chemokine receptor CXCR4 in vitro and in vivo.

Trixie Wagner, Jiri Kovarik, M. Streiff, 2008, Journal of medicinal chemistry.

Valacyclovir for the prevention of cytomegalovirus disease after renal transplantation. International Valacyclovir Cytomegalovirus Prophylaxis Transplantation Study Group.

J. Squifflet, P. Brennan, H. Neumayer, 1999, The New England journal of medicine.

The search for novel adjuvants for early life vaccinations: can "danger" motifs show us the way?

C. Siegrist, J. Kovarik, 2001, Archivum immunologiae et therapiae experimentalis.

Evaluation of tolerability and antibody response after recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) and a single dose of recombinant hepatitis B vaccine.

M. Guillaume, J. Kovarik, P. Tarr, 1996, Vaccine.

Therapeutic activity of multiple common gamma chain cytokine inhibition in acute and chronic GvHD

Franziska, Björn, A. Schmitt-Graeff, 2014 .

Induction of adult-like antibody, Th1, and CTL responses to measles hemagglutinin by early life murine immunization with an attenuated vaccinia-derived NYVAC(K1L) viral vector.

T. Wild, P. Lambert, C. Siegrist, 2001, Virology.

Improved cancer immunotherapy by a CD25-mimobody conferring selectivity to human interleukin-2

B. Brannetti, O. Boyman, L. Sommer, 2016, Science Translational Medicine.

This information is current as Responses Established by Neonatal Priming Vaccines But May Fail to Fully Redirect Th 2 tothe Th 2 Polarization of Neonatal Responses CpG Oligodeoxynucleotides Can Circumvent

P. Lambert, C. Siegrist, J. Kovarik, 1999 .

The Potent Protein Kinase C-Selective Inhibitor AEB071 (Sotrastaurin) Represents a New Class of Immunosuppressive Agents Affecting Early T-Cell Activation

Gerhard Zenke, Volker Brinkmann, Jiri Kovarik, 2009, Journal of Pharmacology and Experimental Therapeutics.

Pharmacokinetics of recombinant human interleukin 3 administered subcutaneously and by continuous intravenous infusion in patients after chemotherapy for ovarian cancer.

N. Mulder, E. de Vries, J. Kovarik, 1993, Cancer research.

The Chemokine Receptor Cxcr3 Is Not Essential for Acute Cardiac Allograft Rejection in Mice and Rats

M. Streiff, G. Wieczorek, M. Hofmann, 2008, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Significance of pre-treatment immunological parameters in colorectal cancer patients with unresectable metastases to the liver.

J. Kovarik, M. Sheard, J. Zaloudik, 1999, Hepato-gastroenterology.

Highly reduced binding to high and low affinity mouse Fc gamma receptors by L234A/L235A and N297A Fc mutations engineered into mouse IgG2a.

G Zenke, S. Geisse, J. Kovarik, 2015, Molecular immunology.

Expression of both Th1 and Th2 cytokines correlates with the histological rejection of MHC‐matched and MHC‐mismatched foetal pancreas allografts in mice

J. Kovarik, M. Koulmanda, T. Mandel, 1997, Immunology and cell biology.

DPP9 enzymatic activity in hematopoietic cells is dispensable for mouse hematopoiesis.

W. Dietrich, A. Rolink, J. Kovarik, 2018, Immunology Letters.

Optimization of vaccine responses in early life: The role of delivery systems and immunomodulators

C. Siegrist, J. Kovarik, 1998, Immunology and cell biology.

Requirement of Mucosa‐Associated Lymphoid Tissue Lymphoma Translocation Protein 1 Protease Activity for Fcγ Receptor–Induced Arthritis, but Not Fcγ Receptor–Mediated Platelet Elimination, in Mice

T. Junt, E. Degl'innocenti, G. Wieczorek, 2020, Arthritis & rheumatology.

The Potent Protein Kinase C-Selective Inhibitor AEB071 (Sotrastaurin) Represents a New Class of Immunosuppressive Agents Affecting Early T-Cell Activation

H. Towbin, G. Baier, V. Brinkmann, 2009, Journal of Pharmacology and Experimental Therapeutics.