D. Flies

发表

Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion

G. Zhu, Lieping Chen, K. Tamada, 2002, Nature Medicine.

Strain‐specific induction of experimental autoimmune prostatitis (EAP) in mice

Christopher M. Jackson, A. Parwani, C. Drake, 2013, The Prostate.

Genomic Organization and Expression Analysis of B7-H4, an Immune Inhibitory Molecule of the B7 Family 1

J. Cheville, G. Zhu, G. Sica, 2003, The Journal of Immunology.

Cutting Edge: Expression of Functional CD137 Receptor by Dendritic Cells1

Lieping Chen, D. Pardoll, K. Tamada, 2002, The Journal of Immunology.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

Manish R. Patel, Charles J. Vaske, Joe Y. Chang, 2016, Journal for Immunotherapy of Cancer.

Modulation of Immune Response by B7 Family Molecules in Tumor Microenvironments

Lieping Chen, D. Flies, 2006, Immunological investigations.

treatment of graft-versus-host disease Selective targeting of the LIGHT-HVEM costimulatory system

G. Zhu, S. Anand, Lieping Chen, 2006 .

The new B7s: playing a pivotal role in tumor immunity.

Lieping Chen, D. Flies, 2007, Journal of immunotherapy.

Coinhibitory receptor PD-1H preferentially suppresses CD4⁺ T cell-mediated immunity.

Lieping Chen, Linghua Zheng, D. Flies, 2014, The Journal of clinical investigation.

Ligation of CD137 receptor prevents and reverses established anergy of CD8+ cytolytic T lymphocytes in vivo.

G. Zhu, Lieping Chen, K. Tamada, 2004, Blood.

Impaired infiltration of tumor-specific cytolytic T cells in the absence of interferon-gamma despite their normal maturation in lymphoid organs during CD137 monoclonal antibody therapy.

Aaron J. Johnson, Hao Wang, Moses Rodriguez, 2002, Cancer research.

Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors.

Aaron J. Johnson, G. Zhu, Lieping Chen, 2002, The Journal of clinical investigation.

Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity.

G. Zhu, Lieping Chen, K. Tamada, 2005, Cancer research.

Immunotherapeutic Potential of B7-DC (PD-L2) Cross-Linking Antibody In Conferring Antitumor Immunity

Moses Rodriguez, Lieping Chen, L. Pease, 2004, Cancer Research.

Role of LAG-3 in regulatory T cells.

C. Drake, D. Pardoll, J. Kowalski, 2004, Immunity.

B7-H3: A costimulatory molecule for T cell activation and IFN-γ production

G. Zhu, G. Sica, Lieping Chen, 2001, Nature Immunology.

B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production.

G. Zhu, G. Sica, K. Tamada, 2001, Nature immunology.

Immune checkpoint blockade reveals the stimulatory capacity of tumor-associated CD103+ dendritic cells in late-stage ovarian cancer

P. Gimotty, D. Flies, S. Adams, 2016, Oncoimmunology.

B7-H1 blockade augments adoptive T-cell immunotherapy for squamous cell carcinoma.

J. Cheville, Lieping Chen, K. Ballman, 2003, Cancer research.

Blockade of LIGHT/LTβ and CD40 signaling induces allospecific T cell anergy, preventing graft-versus-host disease

Lieping Chen, L. Pease, K. Tamada, 2002 .

Rapid tumor vaccine using Toll-like receptor-activated ovarian cancer ascites monocytes

P. Gimotty, G. Coukos, A. Facciabene, 2020, Journal for ImmunoTherapy of Cancer.

B7-H1 determines accumulation and deletion of intrahepatic CD8(+) T lymphocytes.

G. Zhu, Lieping Chen, J. V. van Deursen, 2004, Immunity.

B7-H1 costimulation preferentially enhances CD28-independent T-helper cell function.

G. Zhu, G. Sica, Lieping Chen, 2001, Blood.

Essential role of TNF family molecule LIGHT as a cytokine in the pathogenesis of hepatitis.

G. Zhu, S. Anand, Lieping Chen, 2006, The Journal of clinical investigation.

Progressive Depletion of Peripheral B Lymphocytes in 4-1BB (CD137) Ligand/I-Eα-Transgenic Mice1

G. Zhu, Moses Rodriguez, Lieping Chen, 2001, The Journal of Immunology.

-Transgenic Mice a Lymphocytes in 4-1BB (CD137) Ligand/I-E Progressive Depletion of Peripheral B

G. Zhu, Moses Rodriguez, Lieping Chen, 2001 .

Collagen Fragments Produced in Cancer Mediate T Cell Suppression Through Leukocyte-Associated Immunoglobulin-Like Receptor 1

L. Boon, S. Langermann, R. Copeland, 2021, Frontiers in Immunology.

Blockade of LIGHT/LTbeta and CD40 signaling induces allospecific T cell anergy, preventing graft-versus-host disease.

Lieping Chen, L. Pease, K. Tamada, 2002, The Journal of clinical investigation.

Erratum: Molecular mechanisms of T cell co-stimulation and co-inhibition

Lieping Chen, D. Flies, 2013 .

Enhanced Therapeutic Potential of Adoptive Immunotherapy by In Vitro CD28/4-1BB Costimulation of Tumor-Reactive T Cells Against a Poorly Immunogenic, Major Histocompatibility Complex Class I-Negative A9P Melanoma

D. Sargent, Lieping Chen, K. Tamada, 2000, Journal of immunotherapy.

B7-H3 Enhances Tumor Immunity In Vivo by Costimulating Rapid Clonal Expansion of Antigen-Specific CD8+ Cytolytic T Cells1

G. Zhu, Lieping Chen, K. Tamada, 2004, The Journal of Immunology.

Tolerance to Allogeneic AntigensInduced T Cell - Coinhibitory Receptor Mechanistic Assessment of PD-1H

D. Flies, 2015 .

Cutting Edge: A Monoclonal Antibody Specific for the Programmed Death-1 Homolog Prevents Graft-versus-Host Disease in Mouse Models

Lieping Chen, Shengdian Wang, D. Flies, 2011, The Journal of Immunology.

Graft-versus-Host Disease in Mouse Models for the Programmed Death-1 Homolog Prevents Cutting Edge: A Monoclonal Antibody Specific

Shengdian Wang, D. Flies, Haiying Xu, 2011 .

This information is current as CD 137 Receptor by Dendritic Cells Cutting Edge : Expression of Functional

Lieping Chen, D. Pardoll, K. Tamada, 2002 .

Blockade of the B7-H1/PD-1 Pathway for Cancer Immunotherapy

M. Sznol, Lieping Chen, D. Flies, 2011, The Yale journal of biology and medicine.

Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathway

G. Zhu, G. Sica, Lieping Chen, 2000, Nature Medicine.

Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking human LAIR-collagen interaction

M. Karsdal, S. Langermann, S. Willems, 2021, eLife.

Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy

Xu Zhou, R. Herbst, D. Rimm, 2019, Nature Medicine.

Molecular mechanisms of T cell co-stimulation and co-inhibition

Lieping Chen, D. Flies, 2013, Nature Reviews Immunology.

CTLA-4 Blockade Synergizes Therapeutically with PARP Inhibition in BRCA1-Deficient Ovarian Cancer

P. Gimotty, D. Flies, G. Mantia-Smaldone, 2015, Cancer Immunology Research.

Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion

Haidong Dong, Gefeng Zhu, G. Zhu, 2002, Nature Medicine.

Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking LAIR-collagen interaction

S. Langermann, S. Willems, D. Flies, 2020, bioRxiv.

Molecular Modeling and Functional Mapping of B7-H1 and B7-DC Uncouple Costimulatory Function from PD-1 Interaction

Jürgen Bajorath, Haidong Dong, Tasuku Honjo, 2003, The Journal of experimental medicine.

B7-H4, a molecule of the B7 family, negatively regulates T cell immunity.

G. Zhu, G. Sica, J. Bajorath, 2003, Immunity.

Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen.

C. Drake, D. Pardoll, W. Nelson, 2005, Cancer cell.

Genomic Organization and Expression

J. Cheville, G. Zhu, G. Sica, 2003 .

Costimulating aberrant T cell responses by B7-H1 autoantibodies in rheumatoid arthritis.

G. Zhu, E. Matteson, Lieping Chen, 2003, The Journal of clinical investigation.

B7-h2 is a costimulatory ligand for CD28 in human.

G. Zhu, Lieping Chen, M. Augustine, 2011, Immunity.

Programmed death one homolog maintains the pool size of regulatory T cells by promoting their differentiation and stability

Lieping Chen, D. Flies, Liqun Luo, 2017, Scientific Reports.

Remodeling the tumor microenvironment via blockade of LAIR-1 and TGF-β signaling enables PD-L1–mediated tumor eradication

J. Schlom, Paul L. Chariou, S. Langermann, 2022, The Journal of clinical investigation.

Molecular mechanisms of T cell co-stimulation and co-inhibition

Lieping Chen, D. Flies, 2013, Nature Reviews Immunology.

Strategies for antigen loading of dendritic cells to enhance the antitumor immune response.

R. Vile, Lieping Chen, J. Kasperbauer, 2002, Cancer research.

Cytolytic T Cells + Antigen-Specific CD8 by Costimulating Rapid Clonal Expansion of B7-H3 Enhances Tumor Immunity In Vivo

Dong, Haidong, Lieping, 2004 .

CD8+ cytolytic T lymphocytes in vivo Ligation of CD137 receptor prevents and reverses established anergy of

G. Zhu, Lieping Chen, K. Tamada, 2013 .

PD-1H (VISTA)–mediated suppression of autoimmunity in systemic and cutaneous lupus erythematosus

Tae Kon Kim, Lieping Chen, A. Nassar, 2019, Science Translational Medicine.

Mechanistic Assessment of PD-1H Coinhibitory Receptor–Induced T Cell Tolerance to Allogeneic Antigens

Lieping Chen, D. Flies, T. Higuchi, 2015, The Journal of Immunology.

A simple and rapid vortex method for preparing antigen/adjuvant emulsions for immunization.

Lieping Chen, D. Flies, 2003, Journal of immunological methods.

Tamura, H. et al. B7-H1 costimulation preferentially enhances CD28-independent T-helper cell function. Blood 97, 1809-1816

G. Sica, K. Tamada, H. Tamura, 2001 .

Quantitative, Spatially Defined Expression of Leukocyte-associated Immunoglobulin-like Receptor in Non–small Cell Lung Cancer

D. Rimm, S. Langermann, D. Flies, 2023, Cancer research communications.

Reassessment of CD62L as a Marker of Pre-Effector T Cells in the Tumor Draining Lymph Nodes of Head and Neck Cancer Patients

Lieping Chen, K. Olsen, J. Kasperbauer, 2002, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

Impaired interleukin-10 signaling and ovarian cancer growth in the peritoneal cavity.

D. Flies, S. Adams, T. Ma, 2014 .

Regulation of tumor immunity and immunotherapy by the tumor collagen extracellular matrix

M. Karsdal, S. Langermann, D. Flies, 2023, Frontiers in immunology.

Erratum: Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion (Nature Medicine (2002) 8 (793-800))

G. Zhu, Lieping Chen, K. Tamada, 2002 .

Coinhibitory receptor PD-1H preferentially suppresses CD4⁺ T cell-mediated immunity.

Lieping Chen, Linghua Zheng, D. Flies, 2014, The Journal of clinical investigation.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

Charles J. Vaske, Joe Y. Chang, Scott R. Presnell, 2016, Journal for ImmunoTherapy of Cancer.

Leukocyte-associated immunoglobulin-like receptor-1 blockade in combination with programmed death-ligand 1 targeting therapy mediates increased tumour control in mice

R. Lebbink, D. Flies, D. Bihan, 2024, Cancer immunology, immunotherapy : CII.

Immune checkpoint blockade reveals the stimulatory capacity of tumor-associated CD103+ dendritic cells in late-stage ovarian cancer

P. Gimotty, D. Flies, S. Adams, 2016, Oncoimmunology.

The FLRT3-UNC5B checkpoint pathway inhibits T cell–based cancer immunotherapies

D. Langenau, D. Flies, Qiqi Yang, 2024, Science advances.

Blocking the regulatory T cell molecule LAG-3 augments in vivo anti-tumor immunity in an autochthonous model of prostate cancer.

D. Getnet, C. Drake, D. Flies, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

CD137 Receptor by Dendritic Cells Cutting Edge: Expression of Functional

Lieping Chen, D. Pardoll, K. Tamada, 2002 .

This information is current as CD 137 Receptor by Dendritic Cells Cutting Edge : Expression of Functional

A. Chapoval, T. Shin, D. Flies, 2002 .