Shinichi Takahashi

发表

Neuroprotective Role of Astroglia in Parkinson Disease by Reducing Oxidative Stress Through Dopamine-Induced Activation of Pentose-Phosphate Pathway

M. Suematsu, N. Suzuki, K. Mashima, 2018, ASN neuro.

Application of q-Space Diffusion MRI for the Visualization of White Matter

H. Okano, M. Jinzaki, K. Hikishima, 2016, The Journal of Neuroscience.

Neuroprotective Function of High Glycolytic Activity in Astrocytes: Common Roles in Stroke and Neurodegenerative Diseases

Shinichi Takahashi, 2021, International journal of molecular sciences.

Stroke therapy through the regulation of glial cell interaction

Shinichi Takahashi, 2016 .

Roles and Regulation of Ketogenesis in Cultured Astroglia and Neurons Under Hypoxia and Hypoglycemia

N. Suzuki, K. Mashima, Shinichi Takahashi, 2014, ASN neuro.

Cellular Origin and Regulation of D-and L-Serine in in Vitro and in Vivo Models of Cerebral Ischemia

N. Suzuki, K. Hamase, K. Mashima, 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Cilostazol Enhances Oxidative Glucose Metabolism in Both Neurons and Astroglia without Increasing Ros Production

N. Suzuki, Shinichi Takahashi, Y. Izawa, 2011 .

Nitric oxide–cGMP–protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC6

Y. Mori, N. Takami, M. Mori, 2008, The Journal of physiology.

Rivaroxaban Promotes Reduction of Embolus Size within Cerebrocortical Microvessels in a Mouse Model of Embolic Stroke.

N. Suzuki, Shinichi Takahashi, T. Abe, 2019, The Keio journal of medicine.

Case report of a 28-year-old male with the rapid progression of steroid-resistant central nervous system vasculitis diagnosed by a brain biopsy.

H. Hattori, N. Suzuki, Shinichi Takahashi, 2017, Rinsho shinkeigaku = Clinical neurology.

Platelet responsiveness to in vitro aspirin is independent of COX-1 and COX-2 protein levels and polymorphisms.

M. Murata, Y. Ikeda, Shinichi Takahashi, 2008, Thrombosis research.

Increased basal platelet activity, plasma adiponectin levels, and diabetes mellitus are associated with poor platelet responsiveness to in vitro effect of aspirin.

Y. Ikeda, M. Murata, Shinichi Takahashi, 2007, Thrombosis research.

Subsequent vascular events after ischemic stroke: the Japan Statin Treatment Against Recurrent Stroke-Longitudinal.

S. Ibayashi, Shotai Kobayashi, K. Kitagawa, 2015, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.

Association between bone scan index and activities of daily living in patients with advanced non-small cell lung cancer

Shinichi Takahashi, Kimiteru Ito, Naoko Shindo, 2017, Supportive Care in Cancer.

Trends of Antiplatelet Therapy for the Management of Moyamoya Disease in Japan: Results of a Nationwide Survey.

K. Houkin, N. Suzuki, Shinichi Takahashi, 2018, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.

Alpha 2A adrenergic receptor polymorphism is associated with plasma von Willebrand factor levels in a general population

M. Murata, Y. Ikeda, Shinichi Takahashi, 2008, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Ropinirole hydrochloride remedy for amyotrophic lateral sclerosis – Protocol for a randomized, double-blind, placebo-controlled, single-center, and open-label continuation phase I/IIa clinical trial (ROPALS trial)

H. Okano, H. Saya, N. Suzuki, 2019, Regenerative therapy.

Identification of ADRA2A polymorphisms related to shear-mediated platelet function.

K. Miyaki, M. Murata, Y. Ikeda, 2006, Biochemical and biophysical research communications.

De novo design of RNA-binding proteins with a prion-like domain related to ALS/FTD proteinopathies

D. Ito, N. Suzuki, K. Mashima, 2017, Scientific Reports.

Cerebral Infarction after Transcatheter Aortic Valve Implantation in Japan: Retrospective Analysis at a Single High-Volume Center.

K. Fukuda, J. Nakahara, Shinichi Takahashi, 2019, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.

Human Astrocytes Model Derived from Induced Pluripotent Stem Cells

H. Okano, T. Kondo, K. Mashima, 2020, Cells.

[Astroglial protective mechanisms against ROS under brain ischemia].

Shinichi Takahashi, 2011, Rinsho shinkeigaku = Clinical neurology.

Coagulation Assay and Stroke Severity upon Admission of Patients with Cardioembolic Cerebral Infarction during Direct Oral Anticoagulant Use.

Shinichi Takahashi, M. Takao, T. Osada, 2021, The Keio journal of medicine.

Serial changes of corticospinal tract hyperintensity on magnetic resonance imaging from the preclinical stage in amyotrophic lateral sclerosis

M. Shibata, N. Suzuki, H. Ojima, 2018 .

New onset of myasthenia gravis after intravesical Bacillus Calmette-Guerin

Shigeaki Suzuki, N. Suzuki, J. Nakahara, 2017, Medicine.

Metabolic Contribution and Cerebral Blood Flow Regulation by Astrocytes in the Neurovascular Unit

Shinichi Takahashi, 2022, Cells.

Metabolic compartmentalization between astroglia and neurons in physiological and pathophysiological conditions of the neurovascular unit

Shinichi Takahashi, 2020, Neuropathology : official journal of the Japanese Society of Neuropathology.

Molecular determinants for cardiovascular TRPC6 channel regulation by Ca2+/calmodulin‐dependent kinase II

Y. Mori, Shinichi Takahashi, R. Inoue, 2013, The Journal of physiology.

Differential diagnosis between intracranial dissemination of spinal cord astrocytoma and paraneoplastic limbic encephalitis.

Y. Toyama, Shigeaki Suzuki, N. Suzuki, 2012, Internal medicine.

Ropinirole, a New ALS Drug Candidate Developed Using iPSCs.

H. Okano, Shinichi Takahashi, Daisuke Yasuda, 2020, Trends in pharmacological sciences.

HCO3- secretion by bullfrog duodenum : Dependence on nutrient Na+ during secretory stimulation

D. Soybel, Shinichi Takahashi, W. Silen, 1998 .

Substrate-dependence of reduction of MTT: a tetrazolium dye differs in cultured astroglia and neurons

Y. Fukuuchi, Shinichi Takahashi, T. Abe, 2002, Neurochemistry International.

Nonvalvular atrial fibrillation and stroke

Shinichi Takahashi, 2006 .

A case of spinal and bulbar muscular atrophy with high-stage and high-Gleason Score prostate cancer responded to maximal androgen blockade therapy.

E. Kikuchi, A. Miyajima, M. Oya, 2012, Journal of andrology.

Astroglial pentose phosphate pathway rates in response to high-glucose environments

N. Suzuki, Shinichi Takahashi, Y. Izawa, 2012, ASN neuro.

Oxidative Metabolism in Cultured Rat Astroglia: Effects of Reducing the Glucose Concentration in the Culture Medium and of D-Aspartate or Potassium Stimulation

N. Suzuki, Shinichi Takahashi, T. Abe, 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

A possible role of microglia-derived nitric oxide by lipopolysaccharide in activation of astroglial pentose-phosphate pathway via the Keap1/Nrf2 system

M. Suematsu, K. Mashima, Shinichi Takahashi, 2016, Journal of Neuroinflammation.

Reversible Cerebral Vasoconstriction Syndrome Triggered by Typhoon Hagibis in 2019: Report of 2 Cases

Shinichi Takahashi, M. Takao, T. Osada, 2020, Headache.

Sjögren's syndrome with paresis of the internal branch of the superior laryngeal nerve

S. Nogawa, D. Ito, N. Suzuki, 2014 .

Orexin action on oxytocin neurons in the paraventricular nucleus of the hypothalamus

S. Takenoshita, Y. Ueta, K. Shimomura, 2017, Neuroreport.

[Astrogliopathy as a loss of astroglial protective function against glycoxidative stress under hyperglycemia].

N. Suzuki, Shinichi Takahashi, Y. Izawa, 2012, Rinsho shinkeigaku = Clinical neurology.

Pioglitazone enhances pyruvate and lactate oxidation in cultured neurons but not in cultured astroglia

N. Suzuki, Shinichi Takahashi, Y. Izawa, 2009, Brain Research.

Preservation of autoregulatory cerebral vasodilator responses to hypotension after inhibition of nitric oxide synthesis

L. Sokoloff, C. Kennedy, J. Jehle, 1995, Brain Research.

Lactate and Ketone Bodies Act as Energy Substrates as Well as Signal Molecules in the Brain

Shinichi Takahashi, 2021, Psychology and Patho-physiological Outcomes of Eating [Working Title].

Diameter of fluorescent microspheres determines their distribution throughout the cortical watershed area in mice

N. Suzuki, Shinichi Takahashi, Kazushi Minami, 2018, Brain Research.

Role of Nitric Oxide in the Regulation of Cerebral Blood Flow in Conscious Rats

L. Sokoloff, Shinichi Takahashi, 1998 .

q-Space Myelin Map imaging for longitudinal analysis of demyelination and remyelination in multiple sclerosis patients treated with fingolimod: A preliminary study

H. Okano, M. Jinzaki, J. Hata, 2017, Journal of the Neurological Sciences.

Phase 1/2a clinical trial in ALS with ropinirole, a drug candidate identified by iPSC drug discovery.

H. Okano, M. Jinzaki, D. Ito, 2023, Cell stem cell.

Neuronal-astroglial metabolic compartment as a prime target in novel stroke therapy

Shinichi Takahashi, 2015 .

A possible role of microglia-derived nitric oxide by lipopolysaccharide in activation of astroglial pentose-phosphate pathway via the Keap1/Nrf2 system

M. Suematsu, N. Suzuki, K. Mashima, 2016, Journal of Neuroinflammation.

Diagnostic accuracy of an algorithm for detecting atrial fibrillation in a wrist‐type pulse wave monitor

K. Kario, N. Yasui, Shinichi Takahashi, 2019, Journal of clinical hypertension.

Metabolic properties of astrocytes differentiated from rat neurospheres

N. Suzuki, Shinichi Takahashi, T. Abe, 2006, Brain Research.

Reduction of Alamar Blue, a novel redox indicator, is dependent on both the glycolytic and oxidative metabolism of glucose in rat cultured neurons

Y. Fukuuchi, Shinichi Takahashi, T. Abe, 2002, Neuroscience Letters.

Impact of nonsynonymous mutations of factor X on the functions of factor X and anticoagulant activity of edoxaban

M. Murata, Shinichi Takahashi, T. Shibano, 2015, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Pioglitazone enhances pyruvate and lactate oxidation in cultured neurons but not in cultured astroglia

N. Suzuki, Shinichi Takahashi, Y. Izawa, 2009, Brain Research.

Alpha 2A adrenergic receptor polymorphism is associated with plasma von Willebrand factor levels in a general population

M. Murata, Y. Ikeda, Shinichi Takahashi, 2008, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Rivaroxaban Promotes Reduction of Embolus Size within Cerebrocortical Microvessels in a Mouse Model of Embolic Stroke.

N. Suzuki, Shinichi Takahashi, T. Abe, 2019, The Keio journal of medicine.

FUNCTIONAL ACTIVATION OF ENERGY METABOLISM IN NERVOUS TISSUE: WHERE AND WHY

L. Sokoloff, Shinichi Takahashi, 1996 .

Effects of Fluctuating Glucose Concentrations on Oxidative Metabolism of Glucose in Cultured Neurons and Astroglia

Shinichi Takahashi, Takato Abe, Yoshikane Izawa, 2012 .

GMP-mediated regulation of cardiovascular Ca2+ entry channel TRPC6 and its pathophysiological implications

Shinichi Takahashi, Hai Lin, A. Honda, 2009, BMC Pharmacology.

Protein kinase G (PKG)-mediated tonic inhibition of vascular transient receptor potential (TRP) channel TRPC6

Shinichi Takahashi, A. Honda, R. Inoue, 2007 .

Ipsilateral Facial Tactile Hypesthesia in a Patient with Lateral Medullary Syndrome.

N. Suzuki, J. Nakahara, Shinichi Takahashi, 2015, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.