H. Iinuma

发表

Screening of antibiotics preferentially active against ras oncogene-expressed cells.

H. Naganawa, T. Sawa, M. Hamada, 1990, The Journal of antibiotics.

Studies on a new epidermal growth factor-receptor kinase inhibitor, erbstatin, produced by MH435-hF3.

M. Imoto, T. Takeuchi, K. Isshiki, 1986, The Journal of antibiotics.

Isolation of a novel tyrosine kinase inhibitor, lavendustin A, from Streptomyces griseolavendus.

K. Umezawa, K. Umezawa, H. Naganawa, 1989, Journal of natural products.

Novel antibiotics, amythiamicins. III. Structure elucidations of amythiamicins A, B and C.

Y. Takahashi, H. Naganawa, T. Takeuchi, 1994, The Journal of antibiotics.

Coriolin, a new Basidiomycetes antibiotic.

T. Takeuchi, T. Takita, H. Iinuma, 1969, The Journal of antibiotics.

Panepophenanthrin, from a mushroom strain, a novel inhibitor of the ubiquitin-activating enzyme.

H. Naganawa, T. Takeuchi, H. Iinuma, 2002, Journal of natural products.

Tyropeptins A and B, new proteasome inhibitors produced by Kitasatospora sp. MK993-dF2. I. Taxonomy, isolation, physico-chemical properties and biological activities.

T. Takeuchi, M. Hamada, H. Iinuma, 2001, The Journal of antibiotics.

Structure-based design of derivatives of tyropeptin A as the potent and selective inhibitors of mammalian 20S proteasome.

Y. Umezawa, H. Iinuma, D. Ikeda, 2005, Bioorganic & medicinal chemistry letters.

Tyropeptins A and B, new proteasome inhibitors produced by Kitasatospora sp. MK993-dF2. II. Structure determination and synthesis.

H. Naganawa, T. Takeuchi, H. Iinuma, 2001, The Journal of antibiotics.

Isolation and structural determination of phepropeptins A, B, C, and D, new proteasome inhibitors, produced by Streptomyces sp.

H. Naganawa, T. Takeuchi, M. Hamada, 2001, The Journal of antibiotics.

Biosynthesis of napyradiomycins.

H. Naganawa, T. Takeuchi, K. Isshiki, 1987, The Journal of antibiotics.

Structure of an antitumor antibiotic, spergualin.

T. Takeuchi, H. Umezawa, H. Iinuma, 1981, The Journal of antibiotics.

A new antitumor antibiotic, spergualin: isolation and antitumor activity.

H. Naganawa, T. Takeuchi, M. Hamada, 1981, The Journal of antibiotics.

Decatromicins A and B, new antibiotics produced by Actinomadura sp. MK73-NF4. II. Structure determination.

H. Naganawa, T. Takeuchi, H. Iinuma, 1999, The Journal of antibiotics.

Pholipeptin, a Novel Cyclic Lipoundecapeptide from Pseudomonas fluorescens.

K. Umezawa, M. Imoto, H. Naganawa, 1997 .

Pholipeptin, a Novel Cyclic Lipoundecapeptide fromPseudomonas fluorescens.

K. Umezawa, M. Imoto, H. Naganawa, 1997, The Journal of organic chemistry.

Isolation of a novel paxilline analog pyrapaxilline from fungus that inhibits LPS-induced NO production

K. Umezawa, H. Iinuma, N. Kushida, 2014, The Journal of Antibiotics.

Dethymicin, a novel immunosuppressant isolated from an Amycolatopsis. Fermentation, isolation, physico-chemical properties and biological activities.

H. Naganawa, T. Takeuchi, M. Hamada, 1992, The Journal of antibiotics.

Inhibition of phenylalanine hydroxylase, a pterin-requiring monooxygenase, by oudenone and its derivatives.

S. Koizumi, T. Takeuchi, H. Umezawa, 1982, The Journal of antibiotics.

Inhibition of glucocerebrosidase and induction of neural abnormality by cyclophellitol in mice.

K. Umezawa, H. Iinuma, S. Atsumi, 1992, Archives of biochemistry and biophysics.

Biological activities of cyclophellitol.

K. Umezawa, H. Iinuma, S. Atsumi, 1990, The Journal of antibiotics.

Synthesis and Activity of Tyropeptin A Derivatives as Potent and Selective Inhibitors of Mammalian 20S Proteasome

Y. Umezawa, H. Iinuma, D. Ikeda, 2005, Bioscience, biotechnology, and biochemistry.

Inhibition of Proteasome Activity by Tyropeptin A in PC12 Cells

T. Takeuchi, H. Iinuma, R. Sekizawa, 2002, Bioscience, biotechnology, and biochemistry.

Novel antibiotics napyradiomycins. Production, isolation, physico-chemical properties and biological activity.

H. Naganawa, T. Takeuchi, M. Hamada, 1986, The Journal of antibiotics.

A new antibiotic, structurally related to leptomycin A, flattens the morphology of v-ras(ts) NRK cells.

H. Naganawa, T. Takeuchi, M. Hamada, 1993, The Journal of antibiotics.

New antibiotic napyradiomycins A2 and B4 and stereochemistry of napyradiomycins.

H. Naganawa, T. Takeuchi, H. Umezawa, 1987, Journal of antibiotics (Tokyo. 1968).

IC101, extracellular matrix antagonist produced by Streptomyces sp. MJ202-72F3. Production, isolation, structure determination and biological activity.

H. Naganawa, T. Takeuchi, M. Hamada, 1993, The Journal of antibiotics.

In vitro and in vivo antiprotozoal activities of bispolides and their derivatives

S. Ōmura, Seigo Sato, M. Hatsu, 2010, The Journal of Antibiotics.

Novel Antibiotics, Amythiamicins. Part 2. Structure Elucidation of Amythiamicin D.

H. Naganawa, T. Takeuchi, H. Iinuma, 1995 .

Novel antibiotics, amythiamicins. IV. A mutation in the elongation factor Tu gene in a resistant mutant of B. subtilis.

M. Hamada, M. Hori, H. Iinuma, 1995, The Journal of antibiotics.

Novel antibiotics, amythiamicins. II. Structure elucidation of amythiamicin D.

Y. Takahashi, H. Naganawa, T. Takeuchi, 1994, The Journal of antibiotics.

Novel antibiotics, amythiamicins. I. Taxonomy, fermentation, isolation, physico-chemical properties, and antimicrobial activity.

T. Takeuchi, M. Hamada, H. Iinuma, 1994, The Journal of antibiotics.

Lactonamycin, a new antimicrobial antibiotic produced by Streptomyces rishiriensis MJ773-88K4. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities.

N. Heida, T. Takeuchi, T. Sawa, 1999, The Journal of antibiotics.

Lactonamycin, a new antimicrobial antibiotic produced by Streptomyces rishiriensis MJ773-88K4. II. Structure determination.

Y. Takahashi, H. Naganawa, T. Takeuchi, 1999, The Journal of antibiotics.

Lactonamycin, a new antimicrobial antibiotic produced by Streptomyces rishiriensis.

Y. Takahashi, H. Naganawa, T. Takeuchi, 1996, The Journal of antibiotics.

Polyketomycin, a new antibiotic from Streptomyces sp. MK277-AF1. I. Taxonomy, production, isolation, physico-chemical properties and biological activities.

T. Takeuchi, M. Hamada, H. Iinuma, 1998, The Journal of antibiotics.

New triene-ansamycins, thiazinotrienomycins F and G and a diene-ansamycin, benzoxazomycin.

H. Naganawa, T. Takeuchi, M. Hamada, 2000, The Journal of antibiotics.

Diperamycin, a new antimicrobial antibiotic produced by Streptomyces griseoaurantiacus MK393-AF2. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities.

T. Takeuchi, T. Sawa, M. Hamada, 1998, The Journal of antibiotics.

ISOLATION AND PROPERTIES OF VALANIMYCIN, A NEW

H. Naganawa, M. Hamada, H. Umezawa, 2006 .

Isolation and properties of valanimycin, a new azoxy antibiotic.

H. Naganawa, M. Hamada, H. Umezawa, 1986, The Journal of antibiotics.

Tetrodecamycin and dihydrotetrodecamycin, new antimicrobial antibiotics against Pasteurella piscicida produced by Streptomyces nashvillensis MJ885-mF8. I. Taxonomy, fermentation, isolation, characterization and biological activities.

T. Takeuchi, T. Sawa, M. Hamada, 1995, The Journal of antibiotics.

Tetrodecamycin and dihydrotetrodecamycin, new antimicrobial antibiotics against Pasteurella piscicida produced by Streptomyces nashvillensis MJ885-mF8. II. Structure determination.

Y. Takahashi, H. Naganawa, T. Takeuchi, 1995, The Journal of antibiotics.

Novel Antibiotics, Amythiamicins. Part 3. Structure Elucidations of Amythiamicins A, B, and C.

H. Naganawa, T. Takeuchi, H. Iinuma, 1995 .

Structures of new antibiotics napyradiomycins.

H. Naganawa, T. Takeuchi, K. Isshiki, 1986, The Journal of antibiotics.

Azicemicins A and B, new antimicrobial agents produced by Amycolatopsis. II. Structure determination.

Y. Takahashi, H. Naganawa, T. Takeuchi, 1995, The Journal of antibiotics.

Production, isolation and structure determination of a novel beta-glucosidase inhibitor, cyclophellitol, from Phellinus sp.

K. Umezawa, H. Naganawa, T. Takeuchi, 1990, The Journal of antibiotics.

Derivatives of tetrodecamycin.

T. Takeuchi, T. Sawa, M. Hamada, 1995, The Journal of antibiotics.

Epoxyquinomicins A and B, new antibiotics from Amycolatopsis.

H. Naganawa, T. Takeuchi, T. Sawa, 1996, The Journal of antibiotics.

Anticancer and some biological activities of thiazinotrienomycin B.

T. Yamori, S. Sato, T. Takeuchi, 2000, The Journal of antibiotics.

Effect of diketocoriolin B on antibody formation.

T. Takeuchi, H. Umezawa, H. Iinuma, 1972, The Journal of antibiotics.

Diketocoriolin B, an active derivative of coriolin B produced by Coriolus consors.

T. Takeuchi, H. Umezawa, H. Iinuma, 1971, The Journal of antibiotics.

Basidalin, a new antibiotic from basidiomycetes.

H. Naganawa, T. Takeuchi, H. Umezawa, 1983, The Journal of antibiotics.

Isolation and characterization of a new antibiotic, dioxapyrrolomycin, related to pyrrolomycins.

H. Naganawa, T. Takeuchi, H. Umezawa, 1987, The Journal of antibiotics.

Azicemicin A, a new antimicrobial antibiotic from Amycolatopsis.

Y. Takahashi, H. Naganawa, T. Takeuchi, 1993, The Journal of antibiotics.

Harzianic acid, a new antimicrobial antibiotic from a fungus.

H. Naganawa, T. Takeuchi, M. Hamada, 1994, The Journal of antibiotics.

Histargin, a new inhibitor of carboxypeptidase B, produced by actinomycetes.

T. Aoyagi, H. Naganawa, T. Takeuchi, 1984, The Journal of antibiotics.

2-Amino-5-methyl-5-hexenoic acid, a methionine analog produced by Streptomyces sp. MF374-C4.

T. Takeuchi, H. Umezawa, H. Iinuma, 1979, The Journal of antibiotics.

Nothramicin, a new anthracycline antibiotic from Nocardia sp. MJ896-43F17.

H. Naganawa, T. Takeuchi, M. Hamada, 1998, The Journal of antibiotics.

Polyketomycin, a new antibiotic from Streptomyces sp. MK277-AF1. II. Structure determination.

H. Naganawa, T. Takeuchi, H. Iinuma, 1998, The Journal of antibiotics.

3,4-dihydroxystyrene, a novel microbial inhibitor for phenylalanine hydroxylase and other pteridine-dependent monooxygenases.

S. Koizumi, T. Takeuchi, H. Umezawa, 1984, Biochimica et biophysica acta.

Dopamine -hydroxylase inhibitor produced by Gloeophyllum striatum and its identity with oosponol.

T. Takeuchi, H. Umezawa, H. Iinuma, 1972, The Journal of antibiotics.

Decatromicins A and B, new antibiotics produced by Actinomadura sp. MK73-NF4. I. Taxonomy, isolation, physico-chemical properties and biological activities.

T. Takeuchi, M. Hamada, H. Iinuma, 1999, The Journal of antibiotics.

Accumulation of tissue glucosylsphingosine in Gaucher-like mouse induced by the glucosylceramidase inhibitor cyclophellitol.

K. Umezawa, H. Iinuma, S. Atsumi, 1993, Archives of Biochemistry and Biophysics.

Delaminomycins, novel extracellular matrix receptor antagonist. III. Physico-chemical properties and structure elucidation of delaminomycins B and C.

H. Naganawa, T. Takeuchi, H. Iinuma, 1993, The Journal of antibiotics.

Delaminomycins, novel extracellular matrix receptor antagonist. IV. Structure-activity relationships of delaminomycins and derivatives.

T. Takeuchi, M. Hamada, K. Yamazaki, 1993, The Journal of antibiotics.

Delaminomycins, novel nonpeptide extracellular matrix receptor antagonist and a new class of potent immunomodulator. II. Physico-chemical properties and structure elucidation of delaminomycin A.

H. Naganawa, T. Takeuchi, H. Iinuma, 1993, The Journal of antibiotics.

Delaminomycins, novel nonpeptide extracellular matrix receptor antagonist and a new class of potent immunomodulator. I. Taxonomy, fermentation, isolation and biological activity.

M. Hamada, H. Iinuma, M. Ishizuka, 1993, The Journal of antibiotics.

Suppression of the activities of T-lymphocyte-related enzymes in spleen by administration of an immunosuppressant, 15-deoxyspergualin.

T. Aoyagi, H. Iinuma, A. Ohbayashi, 1989, Biochemistry International.

Inhibition of Experimental Metastasis by an α-Glucosidase Inhibitor, 1,6-Epi-cyclophellitol

K. Umezawa, H. Iinuma, S. Atsumi, 1993 .

Decatromicins A and B, New Antibiotics Produced by Actinomadura sp. MK73-NF4. Part 1. Taxonomy, Isolation, Physico-Chemical Properties, and Biological Activities.

T. Takeuchi, M. Hamada, H. Iinuma, 2000 .

The total synthesis of spergualin, an antitumor antibiotic.

H. Umezawa, H. Iinuma, Y. Ikeda, 1981, The Journal of antibiotics.

Isolation and synthesis of novel farnesyl protein transferase inhibitors, valinoctins A and B, from Streptomyces strain MJ858-NF3.

K. Umezawa, H. Naganawa, T. Takeuchi, 1996, Journal of Natural Products.

New strobilurins O and P from a mushroom.

H. Naganawa, T. Takeuchi, N. Hosokawa, 2000, The Journal of antibiotics.

Synthesis of azepinomycin and its beta-D-ribofuranoside.

Y. Umezawa, Y. Takahashi, H. Naganawa, 1987, The Journal of antibiotics.

Isolation and structure determination of novel phosphatidylinositol kinase inhibitors, echiguanines A and B, from Streptomyces sp.

H. Naganawa, T. Takeuchi, H. Nishioka, 1991, Journal of natural products.

A new antibiotic, calvatic acid.

T. Takeuchi, H. Umezawa, H. Iinuma, 1975, The Journal of antibiotics.

Revised Structure and Stereochemistry of Coriolins

H. Naganawa, T. Takita, H. Umezawa, 1971 .

Monoamine oxidase inhibitors isolated from fermented broths.

T. Takeuchi, H. Iinuma, H. Suda, 1973, Journal of antibiotics (Tokyo. 1968).

The structure of coriolin, a new sesquiterpene antibiotic

T. Takita, H. Umezawa, H. Iinuma, 1969 .

Melleolides K, L and M, new melleolides from Armillariella mellea.

H. Naganawa, T. Takeuchi, M. Hamada, 2000, The Journal of antibiotics.

New antibiotic produced by Micromonospora globosa.

H. Naganawa, T. Takeuchi, M. Hamada, 1990, The Journal of antibiotics.

Isolation of novel saquayamycins as inhibitors of farnesyl-protein transferase.

K. Umezawa, H. Naganawa, T. Takeuchi, 1996, The Journal of antibiotics.

Synthesis and antitumor activity of spergualin analogues. II. Chemical modification of the spermidine moiety.

T. Takeuchi, H. Umezawa, H. Iinuma, 1987, The Journal of antibiotics.

Synthesis and antitumor activity of spergualin analogues. I. Chemical modification of 7-guanidino-3-hydroxyacyl moiety.

T. Takeuchi, H. Umezawa, H. Iinuma, 1985, The Journal of antibiotics.

Cytotoxicity of spergualin and amine oxidase activity in medium.

T. Takeuchi, H. Umezawa, H. Iinuma, 1985, The Journal of antibiotics.

Production of gibberellin-like substance in the embryo of barley during germination

H. Iinuma, H. Yomo, 1966, Planta.

Foroxymithine, a new inhibitor of angiotensin-converting enzyme, produced by actinomycetes.

T. Aoyagi, H. Naganawa, T. Takeuchi, 1985, The Journal of antibiotics.

The Modification of the Ungerminated Barley Endosperm with Gibberellin

H. Iinuma, H. Yomo, 1962 .

Inhibition of Lysenin-induced Hemolysis by All-E-Lutein Derived from the Plant Dalbergia latifolia

K. Umezawa, T. Koyano, H. Iinuma, 2012, Planta Medica.

Epoxyquinomicins A, B, C and D, new antibiotics from Amycolatopsis. I. Taxonomy, fermentation, isolation and antimicrobial activities.

T. Takeuchi, T. Sawa, M. Hamada, 1997, Journal of antibiotics (Tokyo. 1968).

Nothramicin, a New Anthracycline Antibiotic from Nocardia sp. MJ896‐43F17.

H. Naganawa, T. Takeuchi, M. Hamada, 1998 .

Epoxyquinomicins A, B, C and D, new antibiotics from Amycolatopsis. II. Effect on type II collagen-induced arthritis in mice.

T. Takeuchi, T. Sawa, H. Iinuma, 1997, The Journal of antibiotics.

Epoxyquinomicins A, B, C and D, new antibiotics from Amycolatopsis. III. Physico-chemical properties and structure determination.

H. Naganawa, T. Takeuchi, T. Sawa, 1997, The Journal of antibiotics.

Synthesis of anti-rheumatic agent epoxyquinomicin B.

T. Takeuchi, T. Sawa, H. Iinuma, 1998, Bioorganic & medicinal chemistry letters.

Effect on Type II Collagen-induced Arthritis in Mice

H. Iinuma, N. Matsumoto, 2006 .

Inhibition of rat embryo histidine decarboxylase by epoxyquinomicins.

K. Umezawa, T. Takeuchi, T. Sawa, 2000, The Journal of antibiotics.

Epoxyquinomicins A, B, C and D, New Antibiotics from Amycolatopsis. Part 1. Taxonomy, Fermentation, Isolation and Antimicrobial Activities.

T. Takeuchi, T. Sawa, M. Hamada, 1998 .

Inhibition of pinocytosis by hygrolidin family antibiotics: possible correlation with their selective effects on oncogene-expressed cells.

Y. Uehara, H. Naganawa, K. Suzukake-Tsuchiya, 1991, The Journal of antibiotics.

Polyketomycin, a New Antibiotic from Streptomyces sp. MK277-AF1. Part 2. Structure Determination.

H. Naganawa, T. Takeuchi, H. Iinuma, 1998 .

The Enzymes of the Aleurone Layer of Barley Endosperm

H. Iinuma, H. Yomo, 1964 .

The structures of coriolin B and C.

T. Takita, H. Umezawa, H. Iinuma, 1970, Tetrahedron letters.

Some biological and biochemical activities of resormycin, a novel herbicidal antibiotic.

M. Kawada, M. Hamada, M. Hori, 2001, The Journal of antibiotics.

Synthesis of histargin and related compounds and their inhibition of enzymes.

T. Aoyagi, H. Iinuma, F. Kojima, 1988, The Journal of antibiotics.

The structure of histargin.

T. Aoyagi, H. Naganawa, H. Iinuma, 1984, Journal of antibiotics (Tokyo. 1968).

Migracins A and B, new inhibitors of cancer cell migration, produced by Streptomyces sp.

K. Umezawa, H. Iinuma, T. Ukaji, 2012, The Journal of Antibiotics.

Isolation and characterization of terpentecin, a new antitumor antibiotic.

H. Naganawa, T. Takeuchi, K. Isshiki, 1985, The Journal of antibiotics.

Azicemicins A and B, a new antimicrobial agent produced by Amycolatopsis. I. Taxonomy, fermentation, isolation, characterization and biological activities.

T. Takeuchi, T. Sawa, M. Hamada, 1995, The Journal of antibiotics.

Harzianic acid, a new antimicrobial antibiotic from a fungus.

H. Naganawa, T. Takeuchi, M. Hamada, 1994, The Journal of antibiotics.