Sheng Zhou

发表

The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

H. Nakauchi, G. Grosveld, J. Schuetz, 2001, Nature Medicine.

Abcg2 labels multiple cell types in skeletal muscle and participates in muscle regeneration

M. Doyle, B. Olwin, B. Sorrentino, 2011, The Journal of cell biology.

Prospective Isolation of Murine Hematopoietic Stem Cells by Expression of an Abcg2/GFP Allele

J. Rehg, B. Sorrentino, Sheng Zhou, 2006, Stem cells.

Identification of a novel, tissue-specific ABCG2 promoter expressed in pediatric acute megakaryoblastic leukemia.

J. Rubnitz, B. Sorrentino, Sheng Zhou, 2011, Leukemia research.

Route of 41BB/41BBL Costimulation Determines Effector Function of B7-H3-CAR.CD28ζ T Cells

Shondra M. Pruett-Miller, Dalia Haydar, P. Nguyen, 2020, Molecular therapy oncolytics.

Development of a cGMP-compliant process to manufacture donor-derived, CD45RA-depleted memory CD19-CAR T cells

S. Akel, J. Riberdy, S. Gottschalk, 2022, Gene Therapy.

The Art and Science of Selecting a CD123-Specific Chimeric Antigen Receptor for Clinical Testing

B. Ryu, J. Riberdy, R. Throm, 2020, Molecular therapy. Methods & clinical development.

CRISPR-Mediated Non-Viral Site-Specific Gene Integration and Expression in T Cells: Protocol and Application for T-Cell Therapy

Sheng Zhou, Giedre Krenciute, J. Condori, 2020, Cancers.

Marking of definitive HSC precursors in E7.5-E8.5 embryos using an Abcg2-CreER lineage-tracing mouse model.

B. Sorrentino, Sheng Zhou, S. Fatima, 2018, Experimental hematology.

maturation plays a role in decreasing cellular protoporphyrin IX levels Increased expression of the Abcg2 transporter during erythroid

P. Ney, B. Sorrentino, C. Stewart, 2013 .

Increased expression of the Abcg2 transporter during erythroid maturation plays a role in decreasing cellular protoporphyrin IX levels.

P. Ney, B. Sorrentino, C. Stewart, 2005, Blood.

A self-inactivating lentiviral vector for SCID-X1 gene therapy that does not activate LMO2 expression in human T cells.

M. Cavazzana‐Calvo, J. Gray, T. Lu, 2010, Blood.

Optimizing lentiviral vector transduction of hematopoietic stem cells for gene therapy

B. Ryu, D. Rawlings, Yoon-Sang Kim, 2020, Gene Therapy.

STEEL enables high-resolution delineation of spatiotemporal transcriptomic data

F. Zhao, Ji Qi, Sheng Zhou, 2023, Briefings Bioinform..

Lentiviral Gene Therapy Combined with Low‐Dose Busulfan in Infants with SCID‐X1

J. Puck, J. Church, B. Ryu, 2019, The New England journal of medicine.

Preferential expansion of CD8+ CD19-CAR T cells postinfusion and the role of disease burden on outcome in pediatric B-ALL

Y. Li, A. Srinivasan, J. Crawford, 2022, Blood advances.

Lentivector cryptic splicing mediates increase in CD34+ clones expressing truncated HMGA2 in human X-linked severe combined immunodeficiency

L. Notarangelo, J. Puck, S. S. De Ravin, 2022, Nature Communications.

Quantitative shearing linear amplification polymerase chain reaction: an improved method for quantifying lentiviral vector insertion sites in transplanted hematopoietic cell systems.

Yong-Dong Wang, B. Sorrentino, S. S. De Ravin, 2015, Human gene therapy methods.

3’ UTR-truncated HMGA2 overexpression induces non-malignant in vivo expansion of hematopoietic stem cells in non-human primates

S. McKinney-Freeman, Yong-Dong Wang, B. Sorrentino, 2021, Molecular therapy. Methods & clinical development.

Comparison of insulators and promoters for expression of the Wiskott-Aldrich syndrome protein using lentiviral vectors.

A. Nienhuis, B. Sorrentino, Sheng Zhou, 2013, Human gene therapy. Clinical development.

Lentiviral hematopoietic stem cell gene therapy for X-linked severe combined immunodeficiency

L. Notarangelo, J. Gray, D. Kuhns, 2016, Science Translational Medicine.

Evaluating the Safety of Retroviral Vectors Based on Insertional Oncogene Activation and Blocked Differentiation in Cultured Thymocytes

T. Lu, Yong-Dong Wang, B. Sorrentino, 2016, Molecular therapy : the journal of the American Society of Gene Therapy.

Mouse Transplant Models for Evaluating the Oncogenic Risk of a Self-Inactivating XSCID Lentiviral Vector

John T. Gray, J. Gray, T. Lu, 2013, PloS one.

Optimizing lentiviral vector transduction of hematopoietic stem cells for gene therapy

B. Ryu, D. Rawlings, Yoon-Sang Kim, 2020, Gene Therapy.

The Stem Cell Marker Bcrp/ABCG2 Enhances Hypoxic Cell Survival through Interactions with Heme*

J. Schuetz, D. Ross, T. Nakanishi, 2004, Journal of Biological Chemistry.

Production of Lentiviral Vectors Using Suspension Cells Grown in Serum-free Media

B. Ryu, R. Throm, F. Ferrara, 2019, Molecular therapy. Methods & clinical development.

81. Development of a Second Generation Stable Lentiviral Packaging Cell Line in Support of Clinical Gene Transfer Protocols

J. Gray, B. Sorrentino, R. Throm, 2015 .

Efficient construction of producer cell lines for a SIN lentiviral vector for SCID-X1 gene therapy by concatemeric array transfection.

J. Gray, B. Sorrentino, R. Throm, 2009, Blood.

Abcg2 Expression Marks Tissue‐Specific Stem Cells in Multiple Organs in a Mouse Progeny Tracking Model

B. Sorrentino, Sheng Zhou, S. Fatima, 2012, Stem cells.

Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity

Shannon K. Boi, Shondra M. Pruett-Miller, S. Tsai, 2021, Science Translational Medicine.

Interleukin-7 receptor mutants initiate early T cell precursor leukemia in murine thymocyte progenitors with multipotent potential

C. Mullighan, Shann-Ching Chen, M. Churchman, 2014, The Journal of experimental medicine.

Functional interactions between Lmo2, the Arf tumor suppressor, and Notch1 in murine T-cell malignancies.

C. Sherr, T. Lu, B. Sorrentino, 2011, Blood.

Stem cells immortalized by hTERT perform differently from those immortalized by SV40LT in proliferation, differentiation, and reconstruction of matrix microenvironment.

Xiao-Bing Zhang, Sheng Zhou, M. Pei, 2021, Acta biomaterialia.

Expression of Mouse Abcg2 mRNA during Hematopoiesis Is Regulated by Alternative Use of Multiple Leader Exons and Promoters*

B. Sorrentino, Sheng Zhou, Y. Zong, 2006, Journal of Biological Chemistry.

Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo

J. Schuetz, B. Sorrentino, Sheng Zhou, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Downregulation of Prdm16 mRNA is a specific antileukemic mechanism during HOXB4-mediated HSC expansion in vivo.

G. Neale, B. Sorrentino, B. Forget, 2014, Blood.

HEMATOPOIESIS AND STEM CELLS Downregulation of Prdm 16 mRNA is a speci fi c antileukemic mechanism during HOXB 4-mediated HSC expansion in vivo

G. Neale, B. Sorrentino, B. Forget, 2014 .

Hematopoietic cells from mice that are deficient in both Bcrp1/Abcg2 and Mdr1a/1b develop normally but are sensitized to mitoxantrone.

T. Lu, B. Sorrentino, Sheng Zhou, 2003, BioTechniques.

Safety and Anti-Leukemic Activity of CD123-CAR T Cells in Pediatric Patients with AML: Preliminary Results from a Phase 1 Trial

J. Klco, S. Akel, J. Rubnitz, 2022, Blood.

Hemgn is a direct transcriptional target of HOXB4 and induces expansion of murine myeloid progenitor cells.

G. Neale, T. Lu, B. Sorrentino, 2010, Blood.

Development of a cGMP-compliant process to manufacture donor-derived, CD45RA-depleted memory CD19-CAR T cells

S. Akel, J. Riberdy, S. Gottschalk, 2021, Gene Therapy.

Enforced P-glycoprotein pump function in murine bone marrow cells results in expansion of side population stem cells in vitro and repopulating cells in vivo.

T. Lu, B. Sorrentino, Sheng Zhou, 2000, Blood.

Protection and in vivo selection of hematopoietic stem cells using temozolomide, O6-benzylguanine, and an alkyltransferase-expressing retroviral vector.

P. Houghton, T. Brent, B. Sorrentino, 2001, Molecular therapy : the journal of the American Society of Gene Therapy.

STEEL enables high-resolution delineation of spatiotemporal transcriptomic data

F. Zhao, Ji Qi, Sheng Zhou, 2022, Briefings Bioinform..