P. Thibodeau

发表

Structure of nucleotide‐binding domain 1 of the cystic fibrosis transmembrane conductance regulator

J. M. Sauder, S. Burley, W. Hendrickson, 2004, The EMBO journal.

The Cystic Fibrosis-causing Mutation ΔF508 Affects Multiple Steps in Cystic Fibrosis Transmembrane Conductance Regulator Biogenesis*

H. Senderowitz, K. Du, G. Lukács, 2010, The Journal of Biological Chemistry.

CFTR regulatory region interacts with NBD1 predominantly via multiple transient helices

J. Forman-Kay, V. Kanelis, W. Choy, 2007, Nature Structural &Molecular Biology.

Membrane Protein Structure and Folding

P. Thibodeau, A. Zheng, Sophie C. Frizzell, 2020 .

Membrane Protein Folding and Structure

P. Thibodeau, Liang Zhang, 2016 .

Organic Solutes Rescue the Functional Defect in ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator*

P. Thomas, S. Guggino, P. Thibodeau, 2003, Journal of Biological Chemistry.

Stabilization of a nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator yields insight into disease-causing mutations

J. Riordan, R. Vernon, J. Forman-Kay, 2017, The Journal of Biological Chemistry.

Non-native Conformers of Cystic Fibrosis Transmembrane Conductance Regulator NBD1 Are Recognized by Hsp27 and Conjugated to SUMO-2 for Degradation*

G. Lukács, R. Frizzell, P. Thibodeau, 2015, The Journal of Biological Chemistry.

Modulation of the Epithelial Sodium Channel (ENaC) by Bacterial Metalloproteases and Protease Inhibitors

M. Butterworth, P. Thibodeau, R. Shanks, 2014, PloS one.

Calcium-induced Folding and Stabilization of the Pseudomonas aeruginosa Alkaline Protease*

J. Conway, P. Thibodeau, Liang Zhang, 2011, The Journal of Biological Chemistry.

ESCRT-dependent targeting of plasma membrane localized KCa3.1 to the lysosomes.

D. Devor, P. Thibodeau, S. Murray, 2010, American journal of physiology. Cell physiology.

Loss of cardiomyocyte CYB5R3 impairs redox equilibrium and causes sudden cardiac death

Megan P. Miller, G. Salama, B. Kaufman, 2022, The Journal of clinical investigation.

SlpE is a calcium-dependent cytotoxic metalloprotease associated with clinical isolates of Serratia marcescens.

P. Thibodeau, R. Shanks, Jean J. Huang, 2017, Research in microbiology.

Identification of SlpB, a Cytotoxic Protease from Serratia marcescens

P. Thibodeau, R. Shanks, Kimberly M. Brothers, 2015, Infection and Immunity.

Serralysin family metalloproteases protects Serratia marcescens from predation by the predatory bacteria Micavibrio aeruginosavorus

D. Kadouri, Shilpi Gupta, P. Thibodeau, 2018, Scientific Reports.

1 Identification of SlpB , a cytotoxic protease from Serratia marcescens 1 2 3

P. Thibodeau, R. Shanks, Kimberly M. Brothers, 2015 .

Interdomain Contacts and the Stability of Serralysin Protease from Serratia marcescens

Anneliese J. Morrison, P. Thibodeau, Liang Zhang, 2015, PloS one.

Structural analysis reveals pathomechanisms associated with pseudoxanthoma elasticum–causing mutations in the ABCC6 transporter

Yanchao Ran, P. Thibodeau, A. Zheng, 2018, The Journal of Biological Chemistry.

Stabilization of Nucleotide Binding Domain Dimers Rescues ABCC6 Mutants Associated with Pseudoxanthoma Elasticum*

Yanchao Ran, P. Thibodeau, 2016, The Journal of Biological Chemistry.

Regulation of ABCC6 Trafficking and Stability by a Conserved C-terminal PDZ-Like Sequence

P. Thibodeau, Peng Xue, Chelsea M. Crum, 2014, PloS one.

Proteases, cystic fibrosis and the epithelial sodium channel (ENaC)

M. Butterworth, P. Thibodeau, 2013, Cell and Tissue Research.

Activation of the Epithelial Sodium Channel (ENaC) by the Alkaline Protease from Pseudomonas aeruginosa*

M. Myerburg, M. Butterworth, P. Thibodeau, 2012, The Journal of Biological Chemistry.

Side chain and backbone contributions of Phe508 to CFTR folding

Chad A Brautigam, M. Machius, P. Thomas, 2005, Nature Structural &Molecular Biology.

Commentary on Variants in the ABCC6 Gene Implicated in Pseudoxanthoma Elasticum, a Heritable Ectopic Mineralization Disorder.

P. Thibodeau, A. Zheng, 2022, The Journal of investigative dermatology.

Serralysin family metalloproteases protects Serratia marcescens from predation by the predatory bacteria Micavibrio aeruginosavorus

D. Kadouri, Shilpi Gupta, P. Thibodeau, 2018, Scientific Reports.

Mutations in the Yeast Hsp70, Ssa1, at P417 Alter ATP Cycling, Interdomain Coupling, and Specific Chaperone Functions.

G. Chiosis, J. Brodsky, P. Thibodeau, 2015, Journal of molecular biology.

Cystic fibrosis: recent structural insights.

P. Thomas, M. Dorwart, P. Thibodeau, 2004, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Revertant mutants modify, but do not rescue, the gating defect of the cystic fibrosis mutant G551D‐CFTR

M. Amaral, C. Farinha, D. Sheppard, 2014, The Journal of physiology.

Iron bioavailability regulates Pseudomonas aeruginosa interspecies interactions through type VI secretion expression

S. Nouraie, M. Hendricks, J. Bomberger, 2023, Cell reports.

Small heat shock proteins target mutant cystic fibrosis transmembrane conductance regulator for degradation via a small ubiquitin-like modifier–dependent pathway

G. Lukács, R. Frizzell, P. Thibodeau, 2013, Molecular biology of the cell.

Solubilizing mutations used to crystallize one CFTR domain attenuate the trafficking and channel defects caused by the major cystic fibrosis mutation.

M. Amaral, P. Thomas, C. Farinha, 2008, Chemistry & biology.

NMR evidence for differential phosphorylation‐dependent interactions in WT and ΔF508 CFTR

Julie D Forman-Kay, J. Forman-Kay, V. Kanelis, 2010, The EMBO journal.

A protein sequence that can encode native structure by disfavoring alternate conformations

Min Goo Lee, J. Rizo, J. Hunt, 2002, Nature Structural Biology.

Proteases, cystic fibrosis and the epithelial sodium channel (ENaC)

M. Butterworth, P. Thibodeau, 2012, Cell and Tissue Research.

Molecular modeling tools and approaches for CFTR and cystic fibrosis.

Adrian W. R. Serohijos, N. Dokholyan, P. Thibodeau, 2011, Methods in molecular biology.

Inducible Polymerization and Two-Dimensional Assembly of the Repeats-in-Toxin (RTX) Domain from the Pseudomonas aeruginosa Alkaline Protease

D. Stolz, J. Conway, P. Thibodeau, 2014, Biochemistry.

SlpE is a calcium-dependent cytotoxic metalloprotease associated with clinical isolates of Serratia marcescens.

P. Thibodeau, R. Shanks, Jean J. Huang, 2017, Research in microbiology.