A. Krantz

发表

Diversification of the drug discovery process

A. Krantz, 1998, Nature Biotechnology.

Inactivation of a cytosolic phospholipase A2 by thiol-modifying reagents: cysteine residues as potential targets of phospholipase A2.

Z. Yuan, B. Li, A. Krantz, 1994, Biochemistry.

Allenic suicide substrates: new inhibitors of vitamin B6 linked decarboxylases

A. Krantz, A. Castelhano, D. Pliura, 1984 .

Site-specific Labeling of a Protein Lysine Residue By Novel Kinetic Labeling Combinatorial Libraries

J. Wolff, A. Krantz, Linda Huang, 2014, Computational and structural biotechnology journal.

Nature of papain products resulting from inactivation by a peptidyl O‐acyl hydroxamate

R. Ménard, A. Krantz, A. C. Storer, 1991, FEBS letters.

Probing protein surfaces for `hot spots': a new frontier

A. Krantz, 1998 .

New inhibitors of cysteine proteinases. Peptidyl acyloxymethyl ketones and the quiescent nucleofuge strategy

A. Krantz, L. Copp, S. Heard, 1988 .

Comparative behaviour of calpain and cathepsin B toward peptidyl acyloxymethyl ketones, sulphonium methyl ketones and other potential inhibitors of cysteine proteinases.

R. Smith, A. Krantz, D. Pliura, 1992, The Biochemical journal.

Chapter 20. Proteinases in Inflammation

A. Krantz, 1993 .

A classification of enzyme inhibitors

A. Krantz, 1992 .

Site-specific crosslinking of annexin proteins by 1,4-benzoquinone: a novel crosslinker for the formation of protein dimers and diverse protein conjugates.

B. Seaton, Tanya R. Cafarella, A. Krantz, 2012, Organic & biomolecular chemistry.

Phosphatidylserine Sensing by TAM Receptors Regulates AKT-Dependent Chemoresistance and PD-L1 Expression

R. Birge, S. Kotenko, A. Krantz, 2017, Molecular Cancer Research.

Potent inactivation of cathepsins S and L by peptidyl (acyloxy)methyl ketones.

R. Smith, H. Kirschke, D. Brömme, 1994, Biological chemistry Hoppe-Seyler.

A Classification of Enzyme Inhibitors.

A. Krantz, 1993 .

Synthesis and activity of conformationally-constrained macrocyclic norstatine-based inhibitors of HIV protease

A. Krantz, L. Arnold, Roger A. Smith, 1996 .

Pentaammine Complexes of Osmium with pi-Acceptor Ligands.

A. Krantz, A. Holm, H. Taube, 1979 .

Photochemical and Photophysical Studies of Amines with Excited Flavins. Relevance to the Mechanism of Action of the Flavin-Dependent Monoamine Oxidase

A. Krantz, J. Simpson, F. Lewis, 1983 .

Kinetics and mechanism of human leukocyte elastase inactivation by ynenol lactones.

A. Krantz, L. Copp, R. Spencer, 1987, Biochemistry.

Design and synthesis of 4H-3,1-benzoxazin-4-ones as potent alternate substrate inhibitors of human leukocyte elastase.

T. Tam, A. Krantz, L. Copp, 1990, Journal of medicinal chemistry.

Ynenol lactones: synthesis and investigation of reactions relevant to their inactivation of serine proteases

T. Tam, A. Krantz, R. Spencer, 1986 .

A degenerate process in the photoirradiation of matrix-isolated .alpha.-pyrone

A. Krantz, R. Pong, B. Huang, 1977 .

Synthesis of α-amino acids with β,γ-unsaturated side chains

A. Krantz, A. Castelhano, G. J. Taylor, 1988 .

Synthesis, chemistry, and absolute configuration of novel transglutaminase inhibitors containing a 3-halo-4,5-dihydroisoxazole

A. Krantz, A. Castelhano, D. Pliura, 1988 .

Peptidyl (acyloxy)methyl ketones and the quiescent affinity label concept: the departing group as a variable structural element in the design of inactivators of cysteine proteinases.

R. Smith, A. Krantz, L. Copp, 1991, Biochemistry.

Preparation of functionalized isocyanates utilizing a novel, reactive pyridinium salt

A. Krantz, B. Hoppe, 1975 .

Cyclobutadiene. 3. Photolysis of matrix-isolated carbon-13-labeled bicyclopyranones

A. Krantz, R. Pong, B. Huang, 1977 .

Matrix preparation of cyclobutadiene

A. Krantz, C. Y. Lin, A. Krantz, 1972 .

Mechanistic studies on the pyridoxal phosphate enzyme 1-aminocyclopropane-1-carboxylate deaminase from Pseudomonas sp.

R. Raines, C. Walsh, A. Krantz, 1981, Biochemistry.

Novel suicide inhibitors of serine proteinases. Inactivation of human leukocyte elastase by ynenol lactones

T. Tam, A. Krantz, L. Copp, 1984 .

Stereoisomers of allenic amines as inactivators of monoamine oxidase type B. Stereochemical probes of the active site.

R. Smith, A. Krantz, R. L. White, 1988, Journal of medicinal chemistry.

Allenic amino acids. 1. Synthesis of .gamma.-allenic GABA by a novel aza-Cope rearrangement

A. Krantz, A. Castelhano, 1984 .

Studies of mitochondrial monoamine oxidase. Inactivation of the enzyme by isomeric acetylenic and allenic amines yielding muturally exclusive products.

A. Krantz, G. Lipkowitz, 1977, Journal of the American Chemical Society.

Novel indolactam-based inhibitors of matrix metalloproteinases

A. Krantz, N. Dewdney, L. J. Kurz, 1995 .

Characterization of matrix-isolated antiaromatic three-membered heterocycles. Preparation of the elusive thiirene molecule

A. Krantz, J. Laureni, 1981 .

Photolysis of isotopically labeled 1,2,3-selenadiazole and 1,2,3-thiadiazole

A. Krantz, R. Hajdu, J. Laureni, 1976 .

Structural aspects and low-temperature photochemistry of the monothioacetylacetone system

A. Krantz, J. Gebicki, 1981 .

Design of alternate substrate inhibitors of serine proteases. Synergistic use of alkyl substitution to impede enzyme-catalyzed deacylation.

T. Tam, A. Krantz, L. Copp, 1987, Journal of medicinal chemistry.

Inhibition of cathepsin B by peptidyl aldehydes and ketones: slow-binding behavior of a trifluoromethyl ketone.

R. Smith, A. Krantz, L. Copp, 1988, Biochemistry.

Reactions of an electrophilic glycine cation equivalent with grignard reagents a simple synthesis of βX-unsaturated amino acids☆

A. Krantz, A. Castelhano, R. Billedeau, 1986 .

Reactions of an Electrophilic Glycine Cation Equivalent with Grignard Reagents.

A. Krantz, A. Castelhano, R. Billedeau, 1986 .

ALLENIC SUICIDE SUBSTRATES. NEW INHIBITORS OF VITAMIN B6 LINKED DECARBOXYLASES

A. Krantz, A. Castelhano, D. Pliura, 1984 .

Preparation of 1,3-oxazin-6-one. Potential precursor to azacyclobutadiene

A. Krantz, B. Hoppe, 1975 .

Synthesis of 5-alkynylidene-oxazolidin-2-ones☆

T. Tam, A. Krantz, E. Thomas, 1987 .

A METHODOLOGY FOR THE PREPARATION AND CHARACTERIZATION OF THREE-MEMBERED, POTENTIALLY ANTIAROMATIC MOLECULES. PREPARATION OF MATRIX-ISOLATED THIIRENE AND SELENIRENE

A. Krantz, J. Laureni, 1977 .

Matrix photolysis of 1,2,3-thiadiazole. Possible involvement of thiirene

A. Krantz, J. Laureni, 1974 .

Simple method for assigning vibrational frequencies to rapidly equilibrating rotational isomers

A. Krantz, C. Y. Lin, T. Goldfarb, 1972 .

Novel suicide inhibitors of serine proteinases. Inactivation of human leukocyte elastase by ynenol lactones

T. Tam, A. Krantz, L. Copp, 1984 .

Peptidyl (acyloxy)methanes as quiescent affinity labels for cysteine proteinases.

A. Krantz, 1994, Methods in enzymology.

A novel route to allenyl fluorides. Synthesis of 4-amino-7-fluorohepta-5,6-dienoic acid, the first fluoroallenyl amino acid

A. Krantz, A. Castelhano, 1987 .

Design, synthesis, and activity of conformationally-constrained macrocyclic peptide-based inhibitors of HIV protease

A. Krantz, Roger A. Smith, I. Macdonald, 1994 .

Cyclobutadiene. II. Geometry of the matrix-isolated species

M. Newton, A. Krantz, C. Y. Lin, 1973 .

THE COMPLEX FORMATION BETWEEN CADMIUM(2+) AND THE UNSUBSTITUTED BENZENETRICARBOXYLATE IONS

A. Krantz, A. Holm, S. O. Ajayi, 1979 .

Persistence of stereoselectivity in the intramolecular Diels-Alder reactions of 5-alkenylcyclohexa-1,3-dienes. Novel route to functionalized bridged tricyclic rings using a regenerable diene

A. Krantz, C. Y. Lin, 1973 .

Inhibition of serine proteases by benzoxazinones: effects of electron withdrawal and 5-substitution.

T. Tam, A. Krantz, L. Copp, 1986, Biochemical and biophysical research communications.

Trapping of photoenols from o-tolualdehydes in gas matrices. Dependence of photoenol formation on the nature of the carbonyl function

A. Krantz, J. Gebicki, 1984 .

Irreversible inhibition of transglutaminases by sulfonium methylketones: optimization of specificity and potency with omega-aminoacyl spacers.

A. Krantz, D. Pliura, H. Pauls, 1992, Journal of enzyme inhibition.

Inhibition of papain by peptide nitriles

A. Krantz, A. Castelhano, A. C. Storer, 1991 .

MATRIX PHOTOLYSIS OF 1,2,3-THIADIAZOLE, ON THE POSSIBLE INVOLVEMENT OF THIIRENE

A. Krantz, J. Laureni, 1974 .

Solid-state 13C NMR study of a transglutaminase-inhibitor adduct.

R. Griffin, A. McDermott, M. Auger, 1993, Biochemistry.

In vivo inhibition of cathepsin B by peptidyl (acyloxy)methyl ketones.

R. Smith, A. Krantz, L. Copp, 1994, Journal of Medicinal Chemistry.

A new class of mechanism-based inhibitors of transglutaminase enzymes inhibits the formation of cross-linked envelopes by human malignant keratinocytes.

A. Krantz, A. Castelhano, D. Pliura, 1989, Molecular pharmacology.

Molecular Species in Concentrated Aqueous Solutions of Cadmium Halides as Inferred from the Raman Spectra.

T. Østvold, C. Møller, A. Krantz, 1979 .

Juglone: An Organic Chemistry-Ecology Interaction Experiment.

A. Krantz, R. G. Jesaitis, 1972 .

MICROWAVE SPECTRA OF THIOKETENE AND FOUR OF ITS ISOTOPIC SPECIES

O. Nielsen, A. Krantz, A. Holm, 1979 .

Site-directed mutagenesis of Cys324 and Cys331 in human cytosolic phospholipase A2: locus of action of thiol modification reagents leading to inactiviation of cPLA2.

Z. Yuan, B. Li, A. Krantz, 1996, Biochemistry.

Carbon-13 NMR characterization of the papain adduct formed by peptidyl acyloxy-, aryloxy-, and chloromethyl ketone irreversible inhibitors

A. Krantz, Roger A. Smith, H. Pauls, 1992 .

Photochemical generation and detection of an elusive rotamer of matrix-isolated mesityl oxide. Dispersive kinetics of the thermal isomerization: twisted s-trans→ s-cis forms

A. Krantz, J. Gebicki, A. Płonka, 1990 .