Nicholas Waglechner

发表

Antibiotic resistance–mediated isolation of scaffold-specific natural product producers

M. Thaker, Nicholas Waglechner, G. Wright, 2014, Nature Protocols.

Antibiotic Resistance Is Prevalent in an Isolated Cave Microbiome

Andrew C. Pawlowski, K. Bhullar, H. Barton, 2012, PloS one.

The Comprehensive Antibiotic Resistance Database

Andrew C. Pawlowski, M. Mulvey, A. Baylay, 2013, Antimicrobial Agents and Chemotherapy.

A draft genome of Yersinia pestis from victims of the Black Death

Matthias Meyer, David J. D. Earn, Johannes Krause, 2011, Nature.

Yersinia pestis and the plague of Justinian 541-543 AD: a genomic analysis.

Dawn N. Birdsell, D. Earn, E. Holmes, 2014, The Lancet. Infectious diseases.

Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium

Geoffrey L. Winsor, Robert E. W. Hancock, Fiona S. L. Brinkman, 2015, Front. Microbiol..

Characterization of a Rifampin-Inactivating Glycosyltransferase from a Screen of Environmental Actinomycetes

Peter Spanogiannopoulos, Gerard D. Wright, M. Thaker, 2012, Antimicrobial Agents and Chemotherapy.

Discovery of Ibomycin, a Complex Macrolactone that Exerts Antifungal Activity by Impeding Endocytic Trafficking and Membrane Function.

M. Tyers, M. Spitzer, O. Ejim, 2016, Cell chemical biology.

A cryptic polyene biosynthetic gene cluster in Streptomyces calvus is expressed upon complementation with a functional bldA gene.

D. Zechel, Gerard D. Wright, M. Thaker, 2013, Chemistry & biology.

Rifampin phosphotransferase is an unusual antibiotic resistance kinase

P. Stogios, T. Skarina, A. Savchenko, 2016, Nature Communications.

Phylogenetic reconciliation reveals the natural history of glycopeptide antibiotic biosynthesis and resistance

A. McArthur, Gerard D. Wright, Nicholas Waglechner, 2019, Nature Microbiology.

Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling

Y. Brun, Gerard D. Wright, Nicholas Waglechner, 2020, Nature.

Hidden antibiotics in actinomycetes can be identified by inactivation of gene clusters for common antibiotics

Andrew C. Pawlowski, Gerard D. Wright, Nicholas Waglechner, 2019, Nature Biotechnology.

Genomic epidemiology of Mycobacterium abscessus in a Canadian cystic fibrosis centre

M. Behr, V. Waters, E. Tullis, 2022, Scientific Reports.

Harnessing the Synthetic Capabilities of Glycopeptide Antibiotic Tailoring Enzymes: Characterization of the UK‐68,597 Biosynthetic Cluster

Gerard D. Wright, M. Thaker, Nicholas Waglechner, 2014, Chembiochem : a European journal of chemical biology.

CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database

Raymond Lo, Fiona S. L. Brinkman, Mélanie Courtot, 2016, Nucleic Acids Res..

Phylogeny-Informed Synthetic Biology Reveals Unprecedented Structural Novelty in Type V Glycopeptide Antibiotics

G. Wright, Nicholas Waglechner, Wenliang Wang, 2022, ACS central science.

GPAHex-A synthetic biology platform for Type IV–V glycopeptide antibiotic production and discovery

Gerard D. Wright, Nicholas Waglechner, Wenliang Wang, 2020, Nature Communications.

Identifying producers of antibacterial compounds by screening for antibiotic resistance

Nicholas Waglechner, Peter Spanogiannopoulos, Gerard D. Wright, 2013, Nature Biotechnology.

HelR is a helicase-like protein that protects RNA polymerase from rifamycin antibiotics

Gerard D. Wright, Nicholas Waglechner, K. Koteva, 2021, bioRxiv.

A small molecule discrimination map of the antibiotic resistance kinome.

J. E. Blanchard, P. Stogios, A. Savchenko, 2011, Chemistry & biology.

Bacterial inactivation of the anticancer drug doxorubicin.

Gerard D. Wright, Nicholas Waglechner, K. Koteva, 2012, Chemistry & biology.

Biosynthetic gene cluster and antimicrobial activity of the elfamycin antibiotic factumycin

Gerard D. Wright, M. Thaker, Nicholas Waglechner, 2012 .

Inactivation of the Lipopeptide Antibiotic Daptomycin by Hydrolytic Mechanisms

T. Mukhtar, D. Hughes, Gerard D. Wright, 2011, Antimicrobial Agents and Chemotherapy.

Second-pandemic strain of Vibrio cholerae from the Philadelphia cholera outbreak of 1849.

D. Earn, M. Shi, E. Holmes, 2014, The New England journal of medicine.

Eighteenth century Yersinia pestis genomes reveal the long-term persistence of an historical plague focus

E. Holmes, G. B. Golding, J. Krause, 2016, bioRxiv.

IslandViewer 3: more flexible, interactive genomic island discovery, visualization and analysis

Matthew R. Laird, Raymond Lo, Geoffrey L. Winsor, 2015, Nucleic Acids Res..

Antibiotic resistance: it’s bad, but why isn’t it worse?

Gerard D. Wright, Nicholas Waglechner, 2017, BMC Biology.

Vancomycin-Variable Enterococci Can Give Rise to Constitutive Resistance during Antibiotic Therapy

Samir N. Patel, B. Coburn, S. Poutanen, 2014, Antimicrobial Agents and Chemotherapy.

Ancient Antibiotics, Ancient Resistance

Gerard D. Wright, Nicholas Waglechner, Elizabeth J. Culp, 2021, EcoSal Plus.

The Prehistory of Antibiotic Resistance.

Gerard D. Wright, Nicholas Waglechner, J. Perry, 2016, Cold Spring Harbor perspectives in medicine.

The complex resistomes of Paenibacillaceae reflect diverse antibiotic chemical ecologies

Andrew C. Pawlowski, Gerard D. Wright, Nicholas Waglechner, 2018, The ISME Journal.

A rifamycin inactivating phosphotransferase family shared by environmental and pathogenic bacteria

Peter Spanogiannopoulos, Gerard D. Wright, Nicholas Waglechner, 2014, Proceedings of the National Academy of Sciences.

Hidden antibiotics in actinomycetes can be identified by inactivation of gene clusters for common antibiotics

Andrew C. Pawlowski, Gerard D. Wright, Nicholas Waglechner, 2019, Nature Biotechnology.

Erratum: A draft genome of Yersinia pestis from victims of the Black Death

D. Earn, H. Burbano, M. Meyer, 2011 .

Self resistance to the atypical cationic antimicrobial peptide edeine of Brevibacillus brevis Vm4 by the N-acetyltransferase EdeQ.

Gerard D. Wright, Nicholas Waglechner, K. Koteva, 2013, Chemistry and Biology.

The Prehistory of Antibiotic Resistance.

Gerard D. Wright, Nicholas Waglechner, J. Perry, 2016, Cold Spring Harbor perspectives in medicine.