R. Furstoss

发表

Microbiological transformations: 49. Asymmetric biocatalysed Baeyer–Villiger oxidation: improvement using a recombinant Escherichia coli whole cell biocatalyst in the presence of an adsorbent resin

H. D. Simpson, V. Alphand, R. Furstoss, 2001 .

Towards large-scale synthetic applications of Baeyer-Villiger monooxygenases.

J. Woodley, G. Carrea, V. Alphand, 2003, Trends in biotechnology.

Microbial Transformations, 56. Preparative Scale Asymmetric Baeyer–Villiger Oxidation using a Highly Productive “Two‐in‐One” Resin‐Based in situ SFPR Concept

V. Alphand, R. Furstoss, Roland Wohlgemuth, 2004 .

Preparative scale Baeyer–Villiger biooxidation at high concentration using recombinant Escherichia coli and in situ substrate feeding and product removal process

M. Gutiérrez, J. Ward, V. Alphand, 2008, Nature Protocols.

Microbiological transformations. 25. Enantioselective baeyer-villiger oxidation as a tool for the synthesis of enantiopure bicyclic furofuran and pyrofuran chirons.

R. Furstoss, F. Petit, 1993 .

Microbiological transformations. Part 48: Enantioselective biohydrolysis of 2-, 3- and 4-pyridyloxirane at high substrate concentration using the Agrobacterium radiobacter AD1 epoxide hydrolase and its Tyr215Phe mutant

D. Janssen, Y. Genzel, R. Furstoss, 2001 .

Optimizing Fermentation Conditions of Recombinant Escherichia coli Expressing Cyclopentanone Monooxygenase

V. Alphand, R. Furstoss, M. Mihovilovic, 2006 .

Enzymatic transformations. Part 58: Enantioconvergent biohydrolysis of styrene oxide derivatives catalysed by the Solanum tuberosum epoxide hydrolase

R. Furstoss, M. Arand, A. Cronin, 2004 .

Enzymatic transformations. Part 55: Highly productive epoxide hydrolase catalysed resolution of an azole antifungal key synthon

R. Furstoss, A. Archelas, N. Monfort, 2004 .

Enzymatic transformations. Immobilized A. niger epoxide hydrolase as a novel biocatalytic tool for repeated-batch hydrolytic kinetic resolution of epoxides.

R. Fernández-Lafuente, R. Furstoss, C. Mateo, 2003, Organic & biomolecular chemistry.

Preparation of a very stable immobilized Solanum tuberosum epoxide hydrolase

R. Fernández-Lafuente, R. Furstoss, C. Mateo, 2007 .

Biocatalytic Approaches for the Synthesis of Enantiopure Epoxides

R. Furstoss, A. Archelas, 1999 .

Microbiological transformations. 27. The first examples for preparative-scale enantioselective or diastereoselective epoxide hydrolyses using microorganisms. An unequivocal access to all four bisabolol stereoisomers

R. Furstoss, A. Archelas, Ximin Chen, 1993 .

Chromous chloride promoted cyclization of olefinic N-chloro amides. Synthesis of nitrogen heterocycles

B. Waegell, R. Furstoss, R. Côté, 1978 .

Peroxide-initiated cyclizations of olefinic N-chloro amides. Electronic configuration of amido radicals

B. Waegell, R. Furstoss, R. Côté, 1978 .

Comparison of microbiologically and enzymatically mediated Baeyer–Villiger oxidations: synthesis of optically active caprolactones

V. Alphand, R. Furstoss, S. Roberts, 1996 .

Microbiological transformations. 23. A surprising regioselectivity of microbiological Baeyer-Villiger oxidations of menthone and dihydrocarvone

V. Alphand, R. Furstoss, 1992 .

Asymmetric microbiological baeyer-villiger reaction of a bridged bicyclic ketone: divergent behaviour of its enantiomers

V. Alphand, R. Furstoss, H. Griengl, 1991 .

Use of Biooxygenation in Fine Organic Synthesis

R. Furstoss, 1992 .

Microbiological Transformations 15. The Enantioselective Microbiological Baeyer-Villiger Oxidation of Alpha-Substituted Cyclopentanones

V. Alphand, R. Furstoss, A. Archelas, 1990 .

Epoxide Hydrolase‐Catalysed Kinetic Resolution of a Spiroepoxide, a Key Building Block of Various 11‐Heterosteroids

R. Furstoss, A. Archelas, M. Santelli, 2007 .

Microbiological transformations 41.: Screening for novel fungal epoxide hydrolases

R. Furstoss, A. Archelas, P. Moussou, 1998 .

Microbiological transformation 32: Use of epoxide hydrolase mediated biohydrolysis as a way to enantiopure epoxides and vicinal diols: Application to substituted styrene oxide derivatives

R. Furstoss, A. Archelas, S. Pedragosa-Moreau, 1996 .

Role of the quaternary ammonium ion determinants in allergy to muscle relaxants.

J. Charpin, P. Bongrand, M. Senft, 1987, The Journal of allergy and clinical immunology.

Microbiological transformations. 22. Microbiologically mediated Baeyer-Villiger reactions: a unique route to several bicyclic .gamma.-lactones in high enantiomeric purity

V. Alphand, R. Furstoss, 1992 .

Microbial Transformations 16. One-step synthesis of a pivotal prostaglandin chiral synthon via a highly enantioselective microbiological Baeyer-Villiger type reaction

V. Alphand, R. Furstoss, A. Archelas, 1989 .

Microbial transformations. 14. Regioselective hydroxylation of(1R)-caryolanol by aspergillus niger. A reexamination of the 13C NMR spectrum of caryolanol

R. Furstoss, R. Fauré, M. Césario, 1989 .

Transketolase-Mediated Synthesis of 4-Deoxy-d-fructose 6-Phosphate by Epoxide Hydrolase-Catalysed Resolution of 1,1-Diethoxy-3,4-epoxybutane

L. Hecquet, V. Alphand, R. Furstoss, 1999 .

Microbiological Transformations. 33. Fungal Epoxide Hydrolases Applied to the Synthesis of Enantiopure Para-Substituted Styrene Oxides. A Mechanistic Approach.

C. Morisseau, R. Furstoss, J. Baratti, 1996, The Journal of organic chemistry.

Enantioselective synthesis of tert-butyl tert-butanethiosulfinate catalyzed by cyclohexanone monooxygenase.

S. Colonna, G. Carrea, V. Alphand, 2001, Chirality.

Microbiological transformations 36: Preparative scale synthesis of chiral thioacetal and thioketal sulfoxides using whole-cell biotransformations

S. Colonna, V. Alphand, R. Furstoss, 1997 .

Synthesis of optically pure pityol - a pheromone of the bark beetle Pityophthorus pityographus - using a chemoenzymatic route.

R. Furstoss, A. Archelas, 1992 .

Microbial transformationsd. 19. Asymmetric dihydroxylation of the remote double bond of geraniol: a unique stereochemical control allowing easy access to both enantiomers of geraniol-6,7-diol

X. M. Zhang, R. Furstoss, A. Archelas, 1991 .

Bioconversion of sesquiterpenes

R. Furstoss, V. Lamare, 1990 .

Microbial transformations. 10. Evidence for a carbon radical intermediate in the biohydroxylations achieved by the fungus Beauveria sulfurescens

R. Furstoss, A. Archelas, J. Fourneron, 1989 .

Microbial transformations 9. Biohydroxylation of alpha-cedrene and cedrol. Synthesis of an odoriferous minor component of cedar wood essential oil

C. Ehret, R. Furstoss, V. Lamare, 1987 .

Microbial transformations: Part 4(1) Regioselective para hydroxylation of aromatic rings by the fungus beauveria sulfurescens the metabolism of isopropyl n-phenyl

R. Furstoss, A. Archelas, B. Vigne, 1986 .

Microbiological transformations: Hydroxylation of non activated carbons in bridged bicyclic amides.

B. Waegell, R. Furstoss, J. L. Petit, 1980 .

“Microbial transformations 18. Regiospecific para-hydroxylation of aromatic carbamates mediated by the fungus Beauveria sulfurescens”

R. Furstoss, A. Archelas, B. Vigne, 1991 .

Microbial Transformations. Part 18. Regiospecific para‐Hydroxylation of Aromatic Carbamates Mediated by the Fungus Beauveria sulfurescens.

R. Furstoss, A. Archelas, B. Vigne, 1991 .

Microbial transformations 8 first example of a highly enantioselective microbiological hydroxylation process

R. Furstoss, M. Césario, C. Pascard, 1988 .

Highly regioselective double hydroxylation of cyclohexyl N-phenyl carbamate by the fungus Beauveria sulfurescens

R. Furstoss, A. Archelas, B. Vigne, 1987 .

Microbial transformations. Part 7 (1) Biohydroxylation of bornylamide derivatives by the fungus beauveria sulfurescens

R. Furstoss, A. Archelas, B. Vigne, 1987 .

Microbiological transformations 52.: Biocatalysed Baeyer–Villiger oxidation of 1-indanone derivatives

M. Gutiérrez, V. Alphand, R. Furstoss, 2003 .

Microbiological transformations. 28. Enantiocomplementary epoxide hydrolyses as a preparative access to both enantiomers of styrene oxide

R. Furstoss, A. Archelas, S. Pedragosa-Moreau, 1993 .

Microbial transformations. 12. Regiospecific and asymmetric oxidation of the remote double bond of geraniol

R. Furstoss, A. Archelas, J. Fourneron, 1989 .

Microbiological transformations 2. Hydroxylations of non activated carbons in globular type amides.

B. Waegell, R. Furstoss, J. L. Petit, 1981 .

Microbial Transformations. Part 8. First Example of a Highly Enantioselective Microbiological Hydroxylation Process.

R. Furstoss, M. Césario, C. Pascard, 1988 .

Asymmetric hydrolysis of racemic para-nitrostyrene oxide using an epoxide hydrolase preparation from Aspergillus niger

C. Morisseau, R. Furstoss, J. Baratti, 1997 .

Microbiological transformations. Part 51: The first example of a dynamic kinetic resolution process applied to a microbiological Baeyer–Villiger oxidation

V. Alphand, R. Furstoss, N. Berezina, 2002 .

Microbiological Transformations 60. Enantioconvergent Baeyer–Villiger Oxidation via a Combined Whole Cells and Ionic Exchange Resin‐Catalysed Dynamic Kinetic Resolution Process

M. Gutiérrez, V. Alphand, R. Furstoss, 2005 .

Enantiodivergent Chemoenzymatic Synthesis of (R)- and (S)-β-Proline in High Optical Purity

V. Alphand, R. Furstoss, J. Lebreton, 1997 .

Microbiological transformations 35: Enantioselective one-step preparative scale synthesis of 1,3-dithiane-1-oxide via whole-cell bacterial oxidation

S. Colonna, V. Alphand, R. Furstoss, 1996 .

Microbial Baeyer–Villiger oxidation applied to the synthesis of the N-protected (1R,5R)-Geisman–Waiss lactone

M. Gutiérrez, V. Alphand, R. Furstoss, 2005 .

Microbial transformations 59: first kilogram scale asymmetric microbial Baeyer-Villiger oxidation with optimized productivity using a resin-based in situ SFPR strategy.

V. Alphand, R. Furstoss, Roland Wohlgemuth, 2005, Biotechnology and bioengineering.

Microbiological transformations. Part 39: Determination of the regioselectivity occurring during oxirane ring opening by epoxide hydrolases: a theoretical analysis and a new method for its determination

R. Furstoss, J. Baratti, A. Archelas, 1998 .

Epoxide hydrolases and their synthetic applications.

R. Furstoss, K. Faber, R. Orru, 1999, Advances in biochemical engineering/biotechnology.

Synthese de la methyl-6, aza-6, bicyclo (3,2,1) octanone-4

B. Waegell, G. Esposito, R. Furstoss, 1971 .

Flavin-Catalyzed Baeyer−Villiger Reaction of Ketones: Oxidation of Cyclobutanones to γ Lactones Using Hydrogen Peroxide

R. Furstoss, A. Lebreton, C. Mazzini, 1996 .

Microbiological transformations 44. Optimisation of a new Baeyer–Villigerase activity: application to the stereospecific oxidation of 3-phenylcyclobutanone

V. Alphand, R. Furstoss, 2000 .

A new microorganism for highly stereospecific Baeyer–Villiger oxidation of prochiral cyclobutanones

V. Alphand, R. Furstoss, J. Lebreton, 1998 .

Oxidation of some prochiral 3-substituted cyclobutanones using monooxygenase enzymes: a single-step method for the synthesis of optically enriched 3-substituted γ-lactones

V. Alphand, R. Furstoss, G. Grogan, 1995 .

Synthetic applications of epoxide hydrolases.

R. Furstoss, A Archelas, R Furstoss, 2001, Current opinion in chemical biology.

Absolute Configuration of α-Methylstyrene Oxide: The Correct Absolute Configuration/Optical Rotation Correlation

R. Furstoss, A. Archelas, 1999 .

Microbiological transformations 34: Enantioselective hydrolysis of a key-lactone involved in the synthesis of the antidepressant milnacipran®

V. Alphand, R. Furstoss, Pascale Viazzo, 1996 .

Enzymatic Transformations 62. Preparative Scale Synthesis of Enantiopure Glycidyl Acetals using an Aspergillus niger Epoxide Hydrolase-Catalysed Kinetic Resolution

R. Furstoss, B. Doumèche, A. Archelas, 2006 .

Immobilization of the Solanum tuberosum epoxide hydrolase and its application in an enantioconvergent process

S. Karboune, R. Furstoss, J. Baratti, 2005 .

Microbiological transformations. Part 45: A green chemistry preparative scale synthesis of enantiopure building blocks of Eliprodil: elaboration of a high substrate concentration epoxide hydrolase-catalyzed hydrolytic kinetic resolution process

R. Furstoss, J. Baratti, K. Manoj, 2001 .

An integrated chemoenzymatic synthesis of enantiopure (−)-(1R,5S)-cyclosarkomycin: a sarkomycin precursor

V. Alphand, R. Furstoss, J. Lebreton, 1997 .

Enzymatic transformations. Part 53: Epoxide hydrolase-catalysed resolution of key synthons for azole antifungal agents

R. Furstoss, A. Archelas, N. Monfort, 2002 .

Microbiological Transformations. 38. Clues to the Involvement of a General Acid Activation during Hydrolysis of Para-Substituted Styrene Oxides by a Soluble Epoxide Hydrolase from Syncephalastrum racemosum

R. Furstoss, J. Baratti, A. Archelas, 1998 .

Synthesis of N-methyl-6-azabicyclo[3,2,1]octan-3-one, an alkaloid sub-unit

B. Waegell, R. Furstoss, P. Teissier, 1970 .

Determination of the regioselectivity during epoxide hydrolase oxirane ring opening: a new method from racemic epoxides

R. Furstoss, J. Baratti, A. Archelas, 1998 .

Synthesis of enantiopure epoxides through biocatalytic approaches.

R. Furstoss, A. Archelas, and R. Furstoss, 1997, Annual review of microbiology.

A CHEMOENZYMATIC STRATEGY FOR THE SYNTHESIS OF ENANTIOPURE (R)-(-)BACLOFEN

V. Alphand, R. Furstoss, J. Lebreton, 1997 .

Microbiological transformations 57. Facile and efficient resin-based in situ SFPR preparative-scale synthesis of an enantiopure "unexpected" lactone regioisomer via a Baeyer-Villiger oxidation process.

M. Gutiérrez, V. Alphand, R. Furstoss, 2004, Organic letters.

A Chemoenzymatic Strategy for the Synthesis of Enantiopure (R)-(-)- Baclofen.

V. Alphand, R. Furstoss, J. Lebreton, 1997 .

A short chemoenzymatic synthesis of (+)-multifidene and (+)-viridiene

V. Alphand, R. Furstoss, J. Lebreton, 1996 .

Enzymatic Transformations 63. High‐Concentration Two Liquid‐Liquid Phase Aspergillus niger Epoxide Hydrolase‐Catalysed Resolution: Application to Trifluoromethyl‐Substituted Aromatic Epoxides

R. Furstoss, J. Paris, F. Barbirato, 2007 .

Microbiological transformations 50: selection of epoxide hydrolases for enzymatic resolution of 2-, 3- or 4-pyridyloxirane

Q. Broxterman, Y. Genzel, R. Furstoss, 2002 .

On the influence of oxygen and cell concentration in an SFPR whole cell biocatalytic Baeyer–Villiger oxidation process

Roland Wohlgemuth, John Woodley, J. Woodley, 2006, Biotechnology and bioengineering.

Asymmetric Baeyer–Villiger Biooxidation of α‐Substituted Cyanocyclohexanones: Influence of the Substituent Length on Regio‐ and Enantioselectivity

V. Alphand, R. Furstoss, N. Berezina, 2007 .

Microbiological transformations 37. An enantioconvergent synthesis of the β-blocker (R)-Nifénalol® using a combined chemoenzymatic approach

C. Morisseau, R. Furstoss, J. Baratti, 1997 .

Epoxide hydrolases: new tools for the synthesis of fine organic chemicals.

R. Furstoss, A. Archelas, A. Archelas, 1998, Trends in biotechnology.

Enhancing the enantioselectivity of an epoxide hydrolase by directed evolution.

Yvonne Genzel, Manfred T Reetz, Marco Bocola, 2004, Organic letters.

Microbiological transformations. 13. Direct synthesis of both S and R enantiomers of 5-hexadecanolide via an enantioselective microbiological Baeyer-Villiger reaction

V. Alphand, R. Furstoss, A. Archelas, 1990 .

Microbiological transformations--XXIX. Enantioselective hydrolysis of epoxides using microorganisms: a mechanistic study.

R. Furstoss, R Furstoss, A Archelas, 1994, Bioorganic & medicinal chemistry.

Chemoenzymatic synthesis of marine brown algae pheromones

V. Alphand, R. Furstoss, J. Lebreton, 1997 .

Influence of pH on the expression of a recombinant epoxide hydrolase in Aspergillus niger.

Roland Wohlgemuth, Guido Melzer, R. Furstoss, 2009, Biotechnology journal.

A spectrophotometric assay for measuring and detecting an epoxide hydrolase activity.

R. Furstoss, C. Mateo, A. Archelas, 2003, Analytical biochemistry.

Enantioselective hydrolysis of p‐nitrostyrene oxide by an epoxide hydrolase preparation from Aspergillus niger

C. Morisseau, R. Furstoss, J. Baratti, 2000, Biotechnology and bioengineering.

Biocatalytic Potential of the Epoxide Hydrolase from Agrobacterium radiobacter AD1 and a Mutant with Enhanced Enantioselectivity

Dick B. Janssen, D. Janssen, R. Rink, 2002 .

Cloning and molecular characterization of a soluble epoxide hydrolase from Aspergillus niger that is related to mammalian microsomal epoxide hydrolase.

F. Oesch, R. Furstoss, M. Arand, 1999, The Biochemical journal.

Synthesis of bridged azabicyclic ketones. Solvolysis of enol ether ethylene ketal N-cholramines in acidic medium

B. Waegell, G. Esposito, R. Furstoss, 1976 .

Purification and characterization of a highly enantioselective epoxide hydrolase from Aspergillus niger.

C. Morisseau, R. Furstoss, J. Baratti, 1999, European journal of biochemistry.

Microbiological Transformations. 21. An expedient route to both enantiomers of Marmin and Epoxyauraptens via microbiological dihydroxylation of 7-geranyloxycoumarin

X. M. Zhang, R. Furstoss, A. Archelas, 1991 .

Epoxide Hydrolases and Their Synthetic Applications

R. Furstoss, K. Faber, R. Orru, 2010 .

Immobilization of epoxide hydrolase from Aspergillus niger onto DEAE-cellulose: enzymatic properties and application for the enantioselective resolution of a racemic epoxide

S. Karboune, R. Furstoss, J. Baratti, 2005 .

Microbiological transformations. 24. Synthesis of chiral building blocks via stereoselective dihydroxylation of citronellol enantiomers

X. M. Zhang, R. Furstoss, A. Archelas, 1992 .

Microbiological Transformations. Part 24. Synthesis of Chiral Building Blocks via Stereoselective Dihydroxylation of Citronellol Enantiomers.

X. M. Zhang, R. Furstoss, A. Archelas, 1993 .

Microbial transformations 11. Regioselective hydroxylation of β-lactams by the fungus beauveria sulfurescens

R. Furstoss, A. Archelas, J. Fourneron, 1988 .

Microbial Transformations. Part 2. Regioselective Hydroxylation of β-Lactams by the Fungus Beauveria sulfurescens.

R. Furstoss, A. Archelas, J. Fourneron, 1989 .

Microbiological Transformations. Part 6. Biohydroxylations in the Pinane Series.

R. Furstoss, A. Archelas, B. Vigne, 1986 .

Synthesis of All Four Stereoisomers of Enantiomerically Pure cis- and trans-Linalyl Oxides

X. M. Zhang, R. Guglielmetti, R. Furstoss, 1990 .

Microbiological Transformations. Part 28. Enantiocomplementary Epoxide Hydrolyses as a Preparative Access to Both Enantiomers of Styrene Oxide.

R. Furstoss, A. Archelas, S. Pedragosa-Moreau, 1994 .

Characterization of a recombinant Escherichia coli TOP10 [pQR239] whole-cell biocatalyst for stereoselective Baeyer–Villiger oxidations

John M. Woodley, Steven D. Doig, J. Woodley, 2003 .

Microbiological transformations 40. Use of fungal epoxide hydrolases for the synthesis of enantiopure alkyl epoxides

R. Furstoss, A. Archelas, P. Moussou, 1998 .

Microbiological transformations. 31: Synthesis of enantiopure epoxides and vicinal diols using fungal epoxide hydrolase mediated hydrolysis

R. Furstoss, A. Archelas, S. Pedragosa-Moreau, 1996 .

Microbiological transformations. Part 46: Preparation of enantiopure (S)-2-pyridyloxirane via epoxide hydrolase-catalysed kinetic resolution

Q. Broxterman, Y. Genzel, R. Furstoss, 2000 .

Microbiological Transformations 43. Epoxide Hydrolases as Tools for the Synthesis of Enantiopure α-Methylstyrene Oxides: A New and Efficient Synthesis of (S)-Ibuprofen.

R. Furstoss, A. Archelas, M. Cleij, 1999, The Journal of organic chemistry.