Roland Wohlgemuth

发表

Towards large-scale synthetic applications of Baeyer-Villiger monooxygenases.

J. Woodley, G. Carrea, V. Alphand, 2003, Trends in biotechnology.

Microbial Transformations, 56. Preparative Scale Asymmetric Baeyer–Villiger Oxidation using a Highly Productive “Two‐in‐One” Resin‐Based in situ SFPR Concept

V. Alphand, R. Furstoss, Roland Wohlgemuth, 2004 .

Preparative scale Baeyer–Villiger biooxidation at high concentration using recombinant Escherichia coli and in situ substrate feeding and product removal process

M. Gutiérrez, J. Ward, V. Alphand, 2008, Nature Protocols.

Biocatalysis--key to sustainable industrial chemistry.

Roland Wohlgemuth, Roland Wohlgemuth, 2010, Current opinion in biotechnology.

Asymmetric biocatalysis with microbial enzymes and cells.

Roland Wohlgemuth, 2010, Current opinion in microbiology.

Bioeconomy for Sustainable Development

A. Aguilar, Roland Wohlgemuth, T. Twardowski, 2019, Biotechnology journal.

One-pot enzymatic reaction sequence for the syntheses of D-glyceraldehyde 3-phosphate and L-glycerol 3-phosphate

A. Liese, Roland Wohlgemuth, G. Molla, 2016 .

Recombinant Chlorobenzene Dioxygenase from Pseudomonas sp. P51: A Biocatalyst for Regioselective Oxidation of Aromatic Nitriles

A. Schmid, B. Witholt, T. Franko, 2005 .

Asymmetric Baeyer–Villiger Reactions Using Whole‐Cell Biocatalysts

J. Woodley, Roland Wohlgemuth, 2010 .

Tools and ingredients for the biocatalytic synthesis of metabolites

Roland Wohlgemuth, 2009, Biotechnology journal.

Biocatalytic Process Design and Reaction Engineering

Roland Wohlgemuth, 2017 .

A combined experimental and modelling approach for the Weimberg pathway optimisation

J. Snoep, B. Siebers, C. Bräsen, 2020, Nature Communications.

C2-Ketol elongation by transketolase-catalyzed asymmetric synthesis

Roland Wohlgemuth, 2009 .

Semiquantitative Process Screening for the Biocatalytic Synthesis of d-Xylulose-5-phosphate

J. Woodley, Roland Wohlgemuth, Jobin Shaeri, 2006 .

The headgroup conformation of phospholipids in membranes

G. Büldt, Roland Wohlgemuth, 1981, The Journal of Membrane Biology.

Biocatalysis as Key to Sustainable Industrial Chemistry.

R. Sheldon, J. Littlechild, A. Alcántara, 2022, ChemSusChem.

Biocatalytic Phosphorylations of Metabolites: Past, Present, and Future.

A. Liese, W. Streit, Roland Wohlgemuth, 2017, Trends in biotechnology.

Key advances in biocatalytic phosphorylations in the last two decades: Biocatalytic syntheses in vitro and biotransformations in vivo (in humans)

Roland Wohlgemuth, 2020, Biotechnology journal.

Tools and ingredients for the biocatalytic synthesis of carbohydrates and glycoconjugates

Roland Wohlgemuth, 2008 .

Selective hydrolysis of the nitrile group of cis-dihydrodiols from aromatic nitriles

A. Schmid, B. Witholt, Roland Wohlgemuth, 2006 .

Bioreaction Engineering Leading to Efficient Synthesis of L-Glyceraldehyd-3-Phosphate.

A. Liese, W. Streit, Roland Wohlgemuth, 2017, Biotechnology journal.

One-Pot Cascade Reactions using Fructose-6-phosphate Aldolase: Efficient Synthesis of D-Arabinose 5-Phosphate, D-Fructose 6-Phosphate and Analogues

Israel Sánchez-Moreno, E. García-Junceda, F. Charmantray, 2012 .

Desymmetrization of cbz-serinol catalyzed by crude pig pancreatic lipase reveals action of lipases with opposite enantioselectivity

Roland Wohlgemuth, M. El-Behairy, A. Lie, 2013 .

Biocatalytic asymmetric phosphorylation of mevalonate

J. Oost, R. Matsumi, Roland Wohlgemuth, 2014 .

STRENDA DB: enabling the validation and sharing of enzyme kinetics data

Barbara M. Bakker, A. Cornish-Bowden, H. Westerhoff, 2018, The FEBS journal.

Preparative-scale separation by simulated moving bed chromatography of biocatalytically produced regioisomeric lactones.

P. Kaiser, G. Carrea, G. Ottolina, 2009, New biotechnology.

C2-Ketol elongation by transketolase-catalyzed asymmetric synthesis

Roland Wohlgemuth, 2009 .

One-Pot Tandem Enzymatic Reactions for Efficient Biocatalytic Synthesis of D-Fructose-6-Phosphate and Analogs

Israel Sánchez-Moreno, E. García-Junceda, Roland Wohlgemuth, 2016 .

Development of Sustainable Biocatalytic Reduction Processes for Organic Chemists

Roland Wohlgemuth, 2013 .

Highly efficient and scalable chemoenzymatic syntheses of (R)- and (S)-lactaldehydes

Roland Wohlgemuth, R. Meier, B. Schönenberger, 2016 .

Complexity reduction and opportunities in the design, integration and intensification of biocatalytic processes for metabolite synthesis

J. Littlechild, Roland Wohlgemuth, 2022, Frontiers in Bioengineering and Biotechnology.

Epoxide Hydrolases and their Application in Organic Synthesis

Roland Wohlgemuth, M. Kotik, A. Archelas, 2012 .

A generic model-based methodology for quantification of mass transfer limitations in microreactors

Daan Van Hauwermeiren, Timothy Van Daele, K. Gernaey, 2016 .

The Power of Biocatalysts for Highly Selective and Efficient Phosphorylation Reactions

Roland Wohlgemuth, 2022, Catalysts.

Characterisation of a Recombinant NADP‐Dependent Glycerol Dehydrogenase from Gluconobacter oxydans and its Application in the Production of L‐Glyceraldehyde

A. Liese, M. Neumann, T. Eggert, 2009, Chembiochem : a European journal of chemical biology.

Amino acid oxidase-catalysed resolution and Pictet–Spengler reaction towards chiral and rigid unnatural amino acids

Roland Wohlgemuth, P. Benz, 2007 .

Conscious coupling: The challenges and opportunities of cascading enzymatic microreactors.

Frank Baganz, Roland Wohlgemuth, Nicolas Szita, 2017, Biotechnology journal.

7.04 Oxidation by Microbial Methods

Roland Wohlgemuth, 2014 .

Laccase-mediated synthesis of 2-methoxy-3-methyl-5-(alkylamino)- and 3-methyl-2,5-bis(alkylamino)-[1,4]-benzoquinones

U. Bornscheuer, D. Michalik, F. Schauer, 2013 .

Microbial transformations 59: first kilogram scale asymmetric microbial Baeyer-Villiger oxidation with optimized productivity using a resin-based in situ SFPR strategy.

V. Alphand, R. Furstoss, Roland Wohlgemuth, 2005, Biotechnology and bioengineering.

Characterization of a whole‐cell catalyst co‐expressing glycerol dehydrogenase and glucose dehydrogenase and its application in the synthesis of L‐glyceraldehyde

A. Liese, M. Neumann, T. Eggert, 2010, Biotechnology and bioengineering.

Recombinant AroL-Catalyzed Phosphorylation for the Efficient Synthesis of Shikimic Acid 3-Phosphate.

Roland Wohlgemuth, Henrike Brundiek, A. Wszołek, 2018, Biotechnology journal.

High-Yield Biocatalytic Amination Reactions in Organic Synthesis

John M. Ward, Roland Wohlgemuth, J. Ward, 2010 .

INDUSTRIAL BIOTRANSFORMATION *

H. Meyer, Roland Wohlgemuth, O. Ghisalba, 2010 .

Interfacing biocatalysis and organic synthesis

Roland Wohlgemuth, Roland Wohlgemuth, 2007, Journal of Chemical Technology & Biotechnology.

Perspective Interfacing biocatalysis and organic synthesis

Roland Wohlgemuth, 2007 .

The use of enzymes in organic synthesis and the life sciences: perspectives from the Swiss Industrial Biocatalysis Consortium (SIBC)

Roland Wohlgemuth, Steven P. Hanlon, S. Lütz, 2013 .

Biocatalytic asymmetric Michael addition reaction of L-arginine to fumarate for the green synthesis of N-(([(4S)-4-amino-4-carboxy-butyl]amino)iminomethyl)-L-aspartic acid lithium salt (L-argininosuccinic acid lithium salt)

Roland Wohlgemuth, Henrike Brundiek, A. Wszołek, 2017 .

Microbiological transformations 57. Facile and efficient resin-based in situ SFPR preparative-scale synthesis of an enantiopure "unexpected" lactone regioisomer via a Baeyer-Villiger oxidation process.

M. Gutiérrez, V. Alphand, R. Furstoss, 2004, Organic letters.

Mechanistic and kinetics elucidation of Mg2+/ATP molar ratio effect on glycerol kinase

A. Liese, Roland Wohlgemuth, E. Haupt, 2018 .

Biocatalytic Phosphorylation of Metabolites

A. Liese, W. Streit, Roland Wohlgemuth, 2016 .

Perspectives on bioeconomy.

A. Aguilar, Roland Wohlgemuth, T. Twardowski, 2018, New biotechnology.

Efficient Epoxide Hydrolase Catalyzed Resolutions of (+)‐ and (−)‐cis/trans‐Limonene Oxides

D. Monti, S. Riva, Roland Wohlgemuth, 2015 .

2.42 – Product Recovery

R. Wohlgemuth, Roland Wohlgemuth, 2011 .

On the influence of oxygen and cell concentration in an SFPR whole cell biocatalytic Baeyer–Villiger oxidation process

Roland Wohlgemuth, John Woodley, J. Woodley, 2006, Biotechnology and bioengineering.

Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone

Charles P. Lin, Roland Wohlgemuth, Charles P Lin, 2008, Nature Medicine.

Biocatalysis - key enabling tools from biocatalytic one-step and multi-step reactions to biocatalytic total synthesis.

Roland Wohlgemuth, Roland Wohlgemuth, 2020, New biotechnology.

Biocatalysis in the Swiss Manufacturing Environment

Roland Wohlgemuth, Rebecca Buller, Katrin Hecht, 2020, Catalysts.

Large‐Scale Applications of Hydrolases in Biocatalytic Asymmetric Synthesis

Roland Wohlgemuth, 2010 .

Guidelines for reporting of biocatalytic reactions.

Lucia Gardossi, Roland Wohlgemuth, Antonio Ballesteros, 2010, Trends in biotechnology.

Green Production of Fine Chemicals by Isolated Enzymes

Roland Wohlgemuth, 2011 .

Industrial biotechnology in the chemical and pharmaceutical industry

M. Franssen, Roland Wohlgemuth, M. Kircher, 2010 .

Discovery and characterization of thermophilic limonene‐1,2‐epoxide hydrolases from hot spring metagenomic libraries

Xu Peng, Roland Wohlgemuth, Daniela Monti, 2015, The FEBS journal.

Horizons of Systems Biocatalysis and Renaissance of Metabolite Synthesis

Roland Wohlgemuth, 2018, Biotechnology journal.

Discovering novel hydrolases from hot environments.

Peter Menzel, Xu Peng, Roland Wohlgemuth, 2018, Biotechnology advances.

Synthesis of pyridoxamine 5′-phosphate using an MBA:pyruvate transaminase as biocatalyst

J. Ward, Roland Wohlgemuth, U. Schell, 2009, Journal of Molecular Catalysis B: Enzymatic.

Production of epoxide hydrolases in batch fermentations of Botryosphaeria rhodina

S. Junne, D. Hempel, Roland Wohlgemuth, 2008, Journal of Industrial Microbiology & Biotechnology.

Enzymatic synthesis of chiral amino‐alcohols by coupling transketolase and transaminase‐catalyzed reactions in a cascading continuous‐flow microreactor system

Pedro Fernandes, Frank Baganz, Roland Wohlgemuth, 2017, Biotechnology and bioengineering.

Chemical and enzymatic methodologies for the synthesis of enantiomerically pure glyceraldehyde 3-phosphates.

Roland Wohlgemuth, B. Schoenenberger, Dominik Gauss, 2014, Carbohydrate research.

Process analysis of macrotetrolide biosynthesis during fermentation by means of direct infusion LC‐MS

Roland Wohlgemuth, J. Emmert, P. Jani, 2008, Biotechnology journal.

Reactor Operation and Scale‐Up of Whole Cell Baeyer‐Villiger Catalyzed Lactone Synthesis

John M Woodley, Roland Wohlgemuth, Gary J Lye, 2002, Biotechnology progress.

Synthesis of Nω‐Phospho‐l‐arginine by Biocatalytic Phosphorylation of l‐Arginine

Roland Wohlgemuth, Henrike Brundiek, A. Wszołek, 2017 .

Microscale technology and biocatalytic processes: opportunities and challenges for synthesis.

Krist V Gernaey, John M Woodley, Polona Žnidaršič-Plazl, 2015, Trends in biotechnology.

Influence of pH on the expression of a recombinant epoxide hydrolase in Aspergillus niger.

Roland Wohlgemuth, Guido Melzer, R. Furstoss, 2009, Biotechnology journal.

The locks and keys to industrial biotechnology.

Roland Wohlgemuth, Roland Wohlgemuth, 2009, New biotechnology.

Advances in the Synthesis and Analysis of Biologically Active Phosphometabolites

Roland Wohlgemuth, 2023, International journal of molecular sciences.

Chemoenzymatic synthesis of chiral carboxylic acids via nitriles

Roland Wohlgemuth, P. Benz, R. Muntwyler, 2007 .

Enzymatic Synthesis of 2-Keto-3-Deoxy-6-Phosphogluconate by the 6-Phosphogluconate-Dehydratase From Caulobacter crescentus

B. Siebers, E. Allenspach, C. Bräsen, 2020, Frontiers in Bioengineering and Biotechnology.

Efficient biocatalytic synthesis of D-tagatose 1,6-diphosphate by LacC-catalysed phosphorylation of D-tagatose 6-phosphate

T. Eggert, Roland Wohlgemuth, Stefanie Kind, 2020, Biocatalysis and Biotransformation.

Facile synthesis of D-xylulose-5-phosphate and L-xylulose-5-phosphate by xylulokinase-catalyzed phosphorylation

T. Eggert, Roland Wohlgemuth, Stefanie Kind, 2020, Biocatalysis and Biotransformation.

Phosphorylation Catalyzed by Dihydroxyacetone Kinase

Isabel Oroz‐Guinea, Israel Sánchez-Moreno, E. García-Junceda, 2018 .

Biocatalytic Asymmetric Phosphorylation Catalyzed by Recombinant Glycerate‐2‐Kinase

W. Streit, Roland Wohlgemuth, J. Chow, 2017, Chembiochem : a European journal of chemical biology.

Straightforward Synthesis of Terminally Phosphorylated L‐Sugars via Multienzymatic Cascade Reactions

V. Berardinis, Roland Wohlgemuth, M. Lemaire, 2015 .

A combined experimental and modelling approach for the Weimberg pathway optimisation

J. Snoep, B. Siebers, R. Kourist, 2020, Nature Communications.

An empirical analysis of enzyme function reporting for experimental reproducibility: Missing/incomplete information in published papers.

S. Schnell, F. Raushel, J. Rohwer, 2018, Biophysical chemistry.

Bioeconomy Moving forward Step by Step - A Global Journey.

A. Aguilar, Roland Wohlgemuth, T. Twardowski, 2020, New biotechnology.

Bio-based resources, bioprocesses and bioproducts in value creation architectures for bioeconomy markets and beyond – What really matters

Roland Wohlgemuth, 2021 .

Tools for Selective Enzyme Reaction Steps in the Synthesis of Laboratory Chemicals

Roland Wohlgemuth, 2006 .

Dihydroxyacetone kinase-catalyzed Phosphorylation

Isabel Oroz‐Guinea, Israel Sánchez-Moreno, E. García-Junceda, 2018 .

Characterization of enzymatic D‐xylulose 5‐phosphate synthesis

John M Woodley, Roland Wohlgemuth, Jobin Shaeri, 2008, Biotechnology and bioengineering.

Characterization of a phosphotriesterase-like lactonase from the hyperthermoacidophilic crenarchaeon Vulcanisaeta moutnovskia.

J. Littlechild, B. Siebers, Roland Wohlgemuth, 2014, Journal of biotechnology.

One-step synthesis of 2-keto-3-deoxy-d-gluconate by biocatalytic dehydration of d-gluconate.

B. Siebers, D. Esser, C. Bräsen, 2014, Journal of biotechnology.

Microfluidic multi-input reactor for biocatalytic synthesis using transketolase☆

Gary J. Lye, Roland Wohlgemuth, Nicolas Szita, 2013, Journal of molecular catalysis. B, Enzymatic.

The First 200-L Scale Asymmetric Baeyer−Villiger Oxidation Using a Whole-Cell Biocatalyst

John M. Woodley, Roland Wohlgemuth, J. Woodley, 2008 .

Introduction to the Special Issue: Trends in Bioeconomy.

A. Aguilar, Roland Wohlgemuth, T. Twardowski, 2020, New Biotechnology.

Modular and scalable biocatalytic tools for practical safety, health and environmental improvements in the production of speciality chemicals

Roland Wohlgemuth, 2007 .

Economic Considerations for Selecting an Amine Donor in Biocatalytic Transamination

John M. Woodley, Ulrich Krühne, Andreas Vogel, 2015 .

Orientation and flexibility of the choline head group in phosphatidylcholine bilayers.

J. Seelig, G. U. Gally, R. Wohlgemuth, 1977, Biochimica et biophysica acta.

Selective Biocatalytic Defunctionalization of Raw Materials.

Roland Wohlgemuth, 2022, ChemSusChem.

Molecular and Engineering Perspectives of the Biocatalysis Interface to Chemical Synthesis

R. Wohlgemuth, Roland Wohlgemuth, 2011 .

Real-time pH monitoring of industrially relevant enzymatic reactions in a microfluidic side-entry reactor (μSER) shows potential for pH control.

Frank Baganz, Roland Wohlgemuth, Nicolas Szita, 2017, Biotechnology journal.