J. Galman

发表

Discovery, Engineering, and Synthetic Application of Transaminase Biocatalysts

N. Turner, Iustina Slabu, J. Galman, 2017 .

n-Butylamine as an alternative amine donor for the stereoselective biocatalytic transamination of ketones

N. Turner, Iustina Slabu, J. Galman, 2017 .

α,α'-Dihydroxyketone formation using aromatic and heteroaromatic aldehydes with evolved transketolase enzymes.

Mark E. B. Smith, P. Dalby, D. Steadman, 2010, Chemical communications.

Application of a modified Mosher's method for the determination of enantiomeric ratio and absolute configuration at C-3 of chiral 1,3-dihydroxy ketones

H. Hailes, J. Galman, 2009 .

Investigating the reaction mechanism and organocatalytic synthesis of α,α'-dihydroxy ketones.

D. Steadman, H. Hailes, J. Galman, 2012, Organic & biomolecular chemistry.

Stereoselectivity of an ω-transaminase-mediated amination of 1,3-dihydroxy-1-phenylpropane-2-one

Mark E. B. Smith, H. Hailes, J. Ward, 2009 .

Efficient synthesis of α-alkyl-β-amino amides by transaminase-mediated dynamic kinetic resolutions

N. Turner, Iustina Slabu, J. Galman, 2019, Catalysis Science & Technology.

Characterization of imine reductases in reductive amination for the exploration of structure-activity relationships

N. Turner, J. Galman, Ahir Pushpanath, 2020, Science Advances.

Cloning, expression and characterisation of P450-Hal1 (CYP116B62) from Halomonas sp. NCIMB 172: A self-sufficient P450 with high expression and diverse substrate scope.

N. Turner, S. Flitsch, J. Galman, 2018, Enzyme and microbial technology.

Biomimetic synthesis of 2-substituted N-heterocycle alkaloids by one-pot hydrolysis, transamination and decarboxylative Mannich reaction.

F. Parmeggiani, N. Turner, Iustina Slabu, 2018, Chemical communications.

Putrescine Transaminases for the Synthesis of Saturated Nitrogen Heterocycles from Polyamines

N. Turner, Iustina Slabu, J. Galman, 2016 .

Coupling Droplet Microfluidics with Mass Spectrometry for Ultrahigh-Throughput Analysis up to and Above 30Hz.

P. Barran, N. Turner, J. Galman, 2020 .

Biocatalytic retrosynthesis approaches tod-(2,4,5-trifluorophenyl)alanine, key precursor of the antidiabetic sitagliptin

F. Parmeggiani, E. Brenna, Danilo Colombo, 2019, Green Chemistry.

Rapid Screening of Diverse Biotransformations for Enzyme Evolution

F. Parmeggiani, P. Barran, S. Charnock, 2020, JACS Au.

A biocatalytic cascade for the conversion of fatty acids to fatty amines

N. Turner, J. Galman, Sasha R. Derrington, 2019, Green Chemistry.

A Multidisciplinary Approach Toward the Rapid and Preparative-Scale Biocatalytic Synthesis of Chiral Amino Alcohols: A Concise Transketolase-/omega-Transaminase-Mediated Synthesis of (2S,3S)-2-Aminopentane-1,3-diol

B. H. Chen, P. Dalby, J. Woodley, 2010 .

Single-Biocatalyst Synthesis of Enantiopure D-Arylalanines Exploiting an Engineered D-Amino Acid Dehydrogenase

F. Parmeggiani, M. Dunstan, M. Thompson, 2016 .

Monoamine Oxidase: Tunable Activity for Amine Resolution and Functionalization

N. Turner, J. Galman, Artur M. S. Silva, 2018, ACS Catalysis.

A Regio- and Stereoselective ω-Transaminase/Monoamine Oxidase Cascade for the Synthesis of Chiral 2,5-Disubstituted Pyrrolidines

Nicholas J Turner, Elaine O'Reilly, N. Turner, 2014, Angewandte Chemie.

Synthesis of 2,5‐Disubstituted Pyrrolidine Alkaloids via A One‐Pot Cascade Using Transaminase and Reductive Aminase Biocatalysts

Nicholas J. Turner, Anita J. Marsaioli, A. Marsaioli, 2018, ChemCatChem.

One-Pot Biocatalytic Synthesis of Substituted d-Tryptophans from Indoles Enabled by an Engineered Aminotransferase

F. Parmeggiani, N. Turner, J. Galman, 2019, ACS Catalysis.

Consolidated production of coniferol and other high-value aromatic alcohols directly from lignocellulosic biomass

F. Squina, F. Parmeggiani, T. Bugg, 2020, Green Chemistry.

Non-alpha-hydroxylated aldehydes with evolved transketolase enzymes.

P. Dalby, H. Hailes, L. Rios-Solis, 2010, Organic & biomolecular chemistry.

Biocatalytic transamination with near-stoichiometric inexpensive amine donors mediated by bifunctional mono- and di-amine transaminases

Nicholas J. Turner, Fabio Parmeggiani, F. Parmeggiani, 2017 .

An automated microscale platform for evaluation and optimization of oxidative bioconversion processes

H. Hailes, G. Lye, J. Galman, 2012, Biotechnology progress.

One‐Pot Biocatalytic In Vivo Methylation‐Hydroamination of Bioderived Lignin Monomers to Generate a Key Precursor to L‐DOPA

F. Parmeggiani, N. Turner, J. Galman, 2021, Angewandte Chemie.

Coupling Droplet Microfluidics with Mass Spectrometry for Ultrahigh-Throughput Analysis of Complex Mixtures up to and above 30 Hz

P. Barran, N. Turner, J. Galman, 2020, Analytical chemistry.

Characterization of a Putrescine Transaminase From Pseudomonas putida and its Application to the Synthesis of Benzylamine Derivatives

F. Parmeggiani, D. Leys, N. Turner, 2018, Front. Bioeng. Biotechnol..

Zymophore identification enables the discovery of novel phenylalanine ammonia lyase enzymes

Mark S. Dunstan, Nicholas J. Turner, David Leys, 2017, Scientific Reports.

A Regio- and Stereoselective ω-Transaminase/Monoamine Oxidase Cascade for the Synthesis of Chiral 2,5-Disubstituted Pyrrolidines.

Nicholas J. Turner, Elaine O'Reilly, N. Turner, 2014 .

A stereospecific solid-phase screening assay for colonies expressing both (R)- and (S)-selective ω-aminotransferases

N. Turner, Iustina Slabu, J. Galman, 2016, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences.

An automated microscale platform for evaluation and optimization of oxidative bioconversion processes

H. Hailes, G. Lye, J. Galman, 2012, Biotechnology progress.

Immobilization of His6-tagged amine transaminases in microreactors using functionalized nonwoven nanofiber membranes.

J. Galman, P. Žnidaršič-Plazl, Nicholas J. Turner, 2024, New biotechnology.