Yibing Wu

发表

Design of self-assembling transmembrane helical bundles to elucidate principles required for membrane protein folding and ion transport

W. DeGrado, G. Grigoryan, N. Joh, 2017, Philosophical Transactions of the Royal Society B: Biological Sciences.

Consistent blind protein structure generation from NMR chemical shift data

Oliver F. Lange, D. Baker, Gaohua Liu, 2008, Proceedings of the National Academy of Sciences.

Simultaneous prediction of protein folding and docking at high resolution

D. Baker, I. André, Rhiju Das, 2009, Proceedings of the National Academy of Sciences.

Exploring organosilane amines as potent inhibitors and structural probes of influenza a virus M2 proton channel.

R. Lamb, W. DeGrado, L. Pinto, 2011, Journal of the American Chemical Society.

Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus

R. Lamb, M. Klein, W. DeGrado, 2013, Proceedings of the National Academy of Sciences.

Altering the O2-Dependent Reactivity of de novo Due Ferri Proteins

Daniel W. Kulp, W. DeGrado, T. Szyperski, 2012, Nature chemistry.

Erratum: Alteration of the oxygen-dependent reactivity of de novo Due Ferri proteins

Thomas Szyperski, Edward I. Solomon, Hyunil Jo, 2012 .

NMR studies of 4-methylimidazole binding to cytochrome c: effects of methyl substituent on the binding affinity, the orientation of the ligand plane, and the electronic structure of the heme

Yibing Wu, Yong Yao, C. Qian, 2000 .

1H NMR study of 2-methylimidazole binding to cytochrome c: a comprehensive investigation of the role of the methyl substituent on the ligand binding affinity and heme electronic structure in imidazole–cytochrome c complexes

Yibing Wu, Yong Yao, C. Qian, 2001 .

Exploring N-Arylsulfonyl-l-proline Scaffold as a Platform for Potent and Selective αvβ1 Integrin Inhibitors.

W. DeGrado, D. Sheppard, K. Molnar, 2016, ACS medicinal chemistry letters.

Effects of Some Charged Amino Acid Mutations on the Electron Self-Exchange Kinetics of Cytochrome b5

Z. Huang, Yibing Wu, Jun-xia Lu, 1999 .

NMR Structure of Lipoprotein YxeF from Bacillus subtilis Reveals a Calycin Fold and Distant Homology with the Lipocalin Blc from Escherichia coli

B. Rost, G. Montelione, T. Szyperski, 2012, PloS one.

Design of a Short Thermally Stable α‐Helix Embedded in a Macrocycle

W. DeGrado, F. Gai, Yibing Wu, 2018, Chembiochem : a European journal of chemical biology.

Effects of extrinsic imidazole ligation on the molecular and electronic structure of cytochrome c

Gaohua Liu, I. Bertini, L. Banci, 2001, JBIC Journal of Biological Inorganic Chemistry.

A long‐lived Aβ oligomer resistant to fibrillization

S. Prusiner, W. DeGrado, J. Stöhr, 2018, Biopolymers.

X-ray crystal structure of the influenza A M2 proton channel S31N mutant in two conformational states: an open and shut case.

W. DeGrado, Jun Wang, J. Thomaston, 2019, Journal of the American Chemical Society.

Drug-induced conformational and dynamical changes of the S31N mutant of the influenza M2 proton channel investigated by solid-state NMR.

Jonathan K. Williams, W. DeGrado, Jun Wang, 2013, Journal of the American Chemical Society.

Development of α-helical calpain probes by mimicking a natural protein-protein interaction.

Xiaozhen Hu, W. DeGrado, P. Davies, 2012, Journal of the American Chemical Society.

Designed metalloprotein stabilizes a semiquinone radical.

W. DeGrado, Yibing Wu, T. Lemmin, 2016, Nature chemistry.

Flipping in the Pore: Discovery of Dual Inhibitors That Bind in Different Orientations to the Wild-Type versus the Amantadine-Resistant S31N Mutant of the Influenza A Virus M2 Proton Channel

R. Lamb, M. Klein, W. DeGrado, 2014, Journal of the American Chemical Society.

A community resource of experimental data for NMR / X‐ray crystal structure pairs

Rong Xiao, Robert Powers, Thomas Szyperski, 2016, Protein science : a publication of the Protein Society.

Clean absorption-mode NMR data acquisition.

T. Szyperski, Yibing Wu, Arindam Ghosh, 2009, Angewandte Chemie.

A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells.

S. Prusiner, W. DeGrado, G. Stubbs, 2017, Nature chemistry.

Recognition and processing of cisplatin- and oxaliplatin-DNA adducts.

S. Chaney, S. Campbell, Yibing Wu, 2005, Critical reviews in oncology/hematology.

Compositions and conformations of several transition metal complexes with a nonapeptide hormone oxytocin

Zijian Guo, Yibing Wu, Yong Yao, 2000 .

Protein interactions with platinum-DNA adducts: from structure to function.

S. Chaney, S. Campbell, Yibing Wu, 2004, Journal of inorganic biochemistry.

The Tyrosine Kinase c-Src Specifically Binds to the Active Integrin αIIbβ3 to Initiate Outside-in Signaling in Platelets*

W. DeGrado, H. Roder, Hong Cheng, 2015, The Journal of Biological Chemistry.

Computational design of a PAK1 binding protein.

Thomas Szyperski, Andrew Leaver-Fay, Brian Kuhlman, 2010, Journal of molecular biology.

NMR solution structure of an oxaliplatin 1,2-d(GG) intrastrand cross-link in a DNA dodecamer duplex.

Jody M. Havener, J. Swenberg, S. Chaney, 2004, Journal of molecular biology.

NMR solution structure of an oxaliplatin 1,2-d intrastrand cross-link in a DNA dodecamer complex

Jody M. Havener, S. Chaney, S. Campbell, 2003 .

RAP uses a histidine switch to regulate its interaction with LRP in the ER and Golgi.

Irina Mikhailenko, Stephen Lockett, Joseph E Curtis, 2006, Molecular cell.

Zinc-binding structure of a catalytic amyloid from solid-state NMR

W. DeGrado, O. Makhlynets, I. Korendovych, 2017, Proceedings of the National Academy of Sciences.

3-Azatetracyclo[5.2.1.1(5,8).0(1,5)]undecane derivatives: from wild-type inhibitors of the M2 ion channel of influenza A virus to derivatives with potent activity against the V27A mutant.

R. Lamb, W. DeGrado, L. Naesens, 2013, Journal of medicinal chemistry.

New Tricks for Old Proteins: Single Mutations in a Nonenzymatic Protein Give Rise to Various Enzymatic Activities.

Yurii S. Moroz, O. Makhlynets, I. Korendovych, 2015, Journal of the American Chemical Society.

A single mutation in a regulatory protein produces evolvable allosterically regulated catalyst of nonnatural reaction.

Yurii S. Moroz, H. Roder, Hong Cheng, 2013, Angewandte Chemie.

De novo design of a hyperstable non-natural protein-ligand complex with sub-Å accuracy.

Jeff Rawson, David N Beratan, Thomas Lemmin, 2017, Nature chemistry.

Differences in Conformation and Conformational Dynamics Between Cisplatin and Oxaliplatin DNA Adducts

N. Dokholyan, S. Ramachandran, S. Chaney, 2009 .

Solution structures of a DNA dodecamer duplex with and without a cisplatin 1,2-d(GG) intrastrand cross-link: comparison with the same DNA duplex containing an oxaliplatin 1,2-d(GG) intrastrand cross-link.

Irene M. Baskerville-Abraham, J. Swenberg, S. Chaney, 2007, Biochemistry.

Designed Transmembrane Proteins Inhibit the Erythropoietin Receptor in a Custom Binding Topology

W. DeGrado, Hailin Hu, M. Mravic, 2023, bioRxiv.

EMBER multi-dimensional spectral microscopy enables quantitative determination of disease- and cell-specific amyloid strains

W. DeGrado, Yibing Wu, Carlo Condello, 2023, bioRxiv.

Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer’s disease

S. Prusiner, W. DeGrado, L. Lannfelt, 2018, Proceedings of the National Academy of Sciences.

Design of a switchable eliminase

Daniel W. Kulp, W. DeGrado, H. Roder, 2011, Proceedings of the National Academy of Sciences.

De novo design of a transmembrane Zn2+-transporting four-helix bundle

Gevorg Grigoryan, Michael Grabe, Tuo Wang, 2014, Science.

De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures

David Baker, Vikram Khipple Mulligan, Haifan Wu, 2017, Proceedings of the National Academy of Sciences.

NMR study of the conformational transition of cytochrome c upon the displacement of Met80 by exogenous ligand: structural and magnetic characterization of azidoferricytochrome c.

Jinfeng Wang, Yibing Wu, Yong Yao, 2003, Biophysical chemistry.

Residue-Specific Vibrational Echoes Yield 3D Structures of a Transmembrane Helix Dimer

R. Hochstrasser, W. DeGrado, I. Korendovych, 2011, Science.

Specific binding of adamantane drugs and direction of their polar amines in the pore of the influenza M2 transmembrane domain in lipid bilayers and dodecylphosphocholine micelles determined by NMR spectroscopy.

Jun Wang, Mei Hong, W. DeGrado, 2011, Journal of the American Chemical Society.

Asp44 stabilizes the Trp41 gate of the M2 proton channel of influenza A virus.

R. Lamb, M. Klein, W. DeGrado, 2013, Structure.

NMR Structural Studies of Domain 1 of Receptor-associated Protein

Yun-Xing Wang, D. Strickland, Yibing Wu, 2004, Journal of biomolecular NMR.

Computational design of a PAK1 binding protein.

Shuangye Yin, B. Kuhlman, N. Dokholyan, 2010, Journal of molecular biology.

NMR analysis of the αIIbβ3 cytoplasmic interaction suggests a mechanism for integrin regulation

A. Wand, W. DeGrado, K. Valentine, 2010, Proceedings of the National Academy of Sciences.