R. Somerville

发表

Protein-protein interaction in the α-complementation system of β-galactosidase

J. Zeilstra-Ryalls, R. Somerville, 1992 .

A stationary-phase protein of Escherichia coli that affects the mode of association between the trp repressor protein and operator-bearing DNA.

L. Ni, R. Somerville, W. Yang, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing

A. Danchin, Yue-Qing Zhang, S. Ren, 2003, Nature.

The Trp repressor, a ligand-activated regulatory protein.

R. Somerville, 1992, Progress in nucleic acid research and molecular biology.

Structural analysis of the ileR locus of Escherichia coli K12.

R. Somerville, H. Weith, D. I. Johnson, 1986, The Journal of biological chemistry.

Activation of a cryptic pathway for threonine metabolism via specific IS3-mediated alteration of promoter structure in Escherichia coli

B. Aronson, M. Levinthal, R. Somerville, 1989, Journal of bacteriology.

Trp repressor protein controls its own structural gene.

G. Bogosian, R. Somerville, K. Bertrand, 1981, Journal of molecular biology.

Repression of Aromatic Amino Acid Biosynthesis in Escherichia coli K-12

R. Somerville, K. Brown, 1971, Journal of bacteriology.

The ς70 Transcription Factor TyrR Has Zinc-Stimulated Phosphatase Activity That Is Inhibited by ATP and Tyrosine

Shimin Zhao, Qin Zhu, R. Somerville, 2000, Journal of bacteriology.

Uptake and utilization of aromatic d-amino acids in Escherichia coli K12

R. Somerville, J. Kuhn, 1974 .

Nucleotide sequence of the Salmonella typhimurium trpR gene.

R. Somerville, I. Skrypka, 1994, DNA sequence : the journal of DNA sequencing and mapping.

ATPase activity of TyrR, a transcriptional regulatory protein for sigma 70 RNA polymerase.

L. Ni, R. Somerville, J. Cui, 1993, The Journal of biological chemistry.

Functional analysis of E. coli threonine dehydrogenase by means of mutant isolation and characterization.

R. Somerville, E. E. Dekker, Y. Chen, 1995, Biochimica et biophysica acta.

The TyrR protein of Escherichia coli, analysis by limited proteolysis of domain structure and ligand-mediated conformational changes.

R. Somerville, J. Cui, 1993, The Journal of biological chemistry.

Purification and properties of a new aminopeptidase from Escherichia COLI K12.

R. Somerville, L. Yang, 1976, Biochimica et biophysica acta.

The primary structure of Escherichia coli L-threonine dehydrogenase.

B. Aronson, R. Somerville, E. E. Dekker, 1989, The Journal of biological chemistry.

Synechocystis PCC 6803 Contains a Single Gene for the [beta] Subunit of Tryptophan Synthase with Strong Homology to the trpB Genes of Arabidopsis and Maize (Zea mays L.)

R. Somerville, P. Chitnis, G. Zhao, 1994, Plant physiology.

The tpl promoter of Citrobacter freundii is activated by the TyrR protein

R. Somerville, H. Smith, 1997, Journal of bacteriology.

Expression, purification, and functional analysis of the TyrR protein of Haemophilus influenzae.

R. Somerville, S. Zhao, Q. Zhu, 1997, Protein expression and purification.

A mutational analysis of the structural basis for transcriptional activation and monomer-monomer interaction in the TyrR system of Escherichia coli K-12

R. Somerville, J. Cui, 1993, Journal of bacteriology.

Epistasis between deletion mutations in the tryptophan region and mutations affecting the general aromatic pathway in Escherichia coli K-12

R. Somerville, 1967, Journal of bacteriology.

Regulated by the Tryptophan and Tyrosine Repressors in Escherichia coli K-12t

R. Somerville, V. M. Heatwole, 2003 .

Synergism between theTrpRepressor andTyrRepressor in Repression ofthearoLPromoter ofEscherichia coli K-12t

R. Somerville, V. M. Heatwole, 1992 .

Cloning, nucleotide sequence, and characterization of mtr, the structural gene for a tryptophan-specific permease of Escherichia coli K-12

R. Somerville, V. M. Heatwole, 1991, Journal of bacteriology.

Cloning, Nucleotide Sequence, andCharacterization ofmtr,the Structural GeneforaTryptophan-Specific

R. Somerville, 1991 .

Isolation and characterization of mutations creating high-efficiency transcription initiation signals within the trp operon of Escherichia coli

R. Somerville, A. McPartland, 1976, Journal of bacteriology.

Expression of the tryptophan operon in merodiploids of Escherichia coli

R. Somerville, H. Stetson, 2004, Molecular and General Genetics MGG.

Expression of the tryptophan operon in merodiploids ofEscherichia coli

R. Somerville, H. Stetson, 2004, Molecular and General Genetics MGG.

Fluorine-containing analogues of intermediates in the Shikimate pathway.

P. Pilch, R. Somerville, 1976, Biochemistry.

STUDIES ON THE REGULATION OF TRYPTOPHAN BIOSYNTHESIS IN ESCHERICHIA COLI.

C. Yanofsky, R. Somerville, 1965, Journal of molecular biology.

Trp repressor protein is capable of intruding into other amino acid biosynthetic systems

G. Bogosian, R. Somerville, 2004, Molecular and General Genetics MGG.

Transcription of the trpR gene of Escherichia coli: An autogeneously regulated system studied by direct measurements of mRNA levels in vivo

G. Bogosian, F. Imamoto, R. Somerville, 2004, Molecular and General Genetics MGG.

Analysis in vivo of factors affecting the control of transcription initiation at promoters containing target sites for Trp repressor

G. Bogosian, R. Somerville, Ronald L. Somerville, 2004, Molecular and General Genetics MGG.

New regulatory genes involved in the control of transcription initiation at the thr and ilv promoters of Escherichia coli K-12

R. Somerville, Douglas I. Johnson, 2004, Molecular and General Genetics MGG.

Indolmycin-mediated inhibition and stimulation of transcription at the trp promoter of Escherichia coli

G. Bogosian, R. Somerville, P. Haydock, 1983, Journal of bacteriology.

Integration Host Factor and Cyclic AMP Receptor Protein Are Required for TyrR-Mediated Activation of tpl inCitrobacter freundii

R. Somerville, Qing Bai, Ronald L. Somerville, 1998, Journal of bacteriology.

Mutant strains of Escherichia coli K12 that use D-amino acids.

R. Somerville, J. Kuhn, 1971, Proceedings of the National Academy of Sciences of the United States of America.

Structural and functional analysis of a cloned segment of Escherichia coli DNA that specifies proteins of a C4 pathway of serine biosynthesis

R. Somerville, P. Ravnikar, 1987, Journal of bacteriology.

Genetic characterization of a highly efficient alternate pathway of serine biosynthesis in Escherichia coli

R. Somerville, P. Ravnikar, Paula D. RAVNIKARt, 1987, Journal of bacteriology.

Localization of the structural gene for threonine dehydrogenase in Escherichia coli

R. Somerville, P. Ravnikar, 1986, Journal of bacteriology.

Structural and Functional Analysis of a Cloned Segment of Escherichia coli DNA That Specifies Proteins of a C4 Pathway of Serine Biosynthesist

R. Somerville, Paula D. RAVNIKARt, 2022 .

HYDROXYMETHYLDEOXYCYTIDYLATE KINASE FORMATION AFTER BACTERIOPHAGE INFECTION OF ESCHERICHIA COLI.

R. Somerville, G. R. Greenberg, K. Ebisuzaki, 1959, Proceedings of the National Academy of Sciences of the United States of America.

Amino acids : biosynthesis and genetic regulation

K. Herrmann, R. Somerville, 1983 .

Decay rates of Escherichia coli trp messenger RNA molecules lacking the normal 5′-terminal sequences

F. Imamoto, R. Somerville, Y. Kano, 1979, Molecular and General Genetics MGG.

Translation-uncoupled transcription of promoter-proximal DNA sequences in E. coli strains harboring mutationally-generated constitutive promoters within genes of the trp operon

D. Schlessinger, F. Imamoto, R. Somerville, 1979, Molecular and General Genetics MGG.

A human hepatocellular carcinoma 3.0-kilobase DNA sequence transforms both rat liver cells and NIH3T3 fibroblasts and encodes a 52-kilodalton protein.

J. Zeilstra-Ryalls, R. Somerville, K. Zhang, 1990, Cancer research.

Interaction in vivo between strong closely spaced constitutive promoters.

R. Somerville, B. Hausler, Ronald L. Somerville, 1979, Journal of molecular biology.

Cloning the trpR gene

R. Somerville, W. Roeder, 1979, Molecular and General Genetics MGG.

Evidence that repression mechanisms can exert control over the thr, leu, and ilv operons of Escherichia coli K-12

R. Somerville, D. I. Johnson, 1983, Journal of bacteriology.

The tryptophan-specific permease gene, mtr, is differentially regulated by the tryptophan and tyrosine repressors in Escherichia coli K-12

R. Somerville, V. M. Heatwole, 1991, Journal of bacteriology.

Resolution of phage-initiated and normal host thymidylate synthetases of Escherichia coli.

R. Somerville, G. R. Greenberg, S. DeWolf, 1962, Proceedings of the National Academy of Sciences of the United States of America.

Comparison of the Tryptophan Synthetase α Subunits of Several Species of Enterobacteriaceae

C. Yanofsky, T. Creighton, D. Helinski, 1966 .

DNA sequence of the E. coli trpR gene and prediction of the amino acid sequence of Trp repressor.

G. Bogosian, R. Somerville, H. Weith, 1980, Nucleic acids research.

Structural requirements for pep binding To EPSP synthase

E. Logusch, R. Somerville, J. E. Ream, 1991 .

The tyrosine repressor negatively regulates aroH expression in Escherichia coli

K. Herrmann, G. Muday, R. Somerville, 1991, Journal of bacteriology.

Mutant Strains of Escherichia coli K-12 Exhibiting Enhanced Sensitivity to 5-Methyltryptophan

R. Somerville, M. Pabst, J. Kuhn, 1972, Journal of bacteriology.

Deoxyuridylate kinase activity and deoxyuridinetriphosphatase in Escherichia coli.

R. Somerville, G. R. Greenberg, 1962, Proceedings of the National Academy of Sciences of the United States of America.

The tdh and serA operons of Escherichia coli: mutational analysis of the regulatory elements of leucine-responsive genes

B. Aronson, R. Somerville, J. H. Rex, 1991, Journal of bacteriology.

Orientation of the aadA gene within the omega fragment.

J. Zeilstra-Ryalls, R. Somerville, 1990, BioTechniques.

Solution structure of the DNA‐binding domain of the TyrR protein of Haemophilus influenzae

O. Jardetzky, Shimin Zhao, R. Somerville, 2001, Protein science : a publication of the Protein Society.

Gene expression from multicopy T7 promoter vectors proceeds at single copy rates in the absence of T7 RNA polymerase.

R. Somerville, T. Shieh, J. Cui, 1991, Biochemical and biophysical research communications.

Biological Limitations on the Length of Highly Repetitive DNA Sequences that May be Stably Maintained within Plasmid Replicons in Escherichia coli

R. Somerville, H. Weith, SubhashC . Gupta, 1983, Bio/Technology.

Shared operator recognition specificity between Trp repressor and the repressors of bacteriophage 434.

G. Bogosian, J. Zeilstra-Ryalls, R. Somerville, 1991, Journal of molecular biology.

Ecological interference between fatal diseases

Yue-Qing Zhang, You-Gang Miao, Zhu Chen, 2003 .

ON THE TRANSLATION OF THE A GENE REGION OF TRYPTOPHAN MESSENGER RNA.

C. Yanofsky, R. Somerville, 1964, Journal of molecular biology.

Synergism between the Trp repressor and Tyr repressor in repression of the aroL promoter of Escherichia coli K-12

R. Somerville, V. M. Heatwole, 1992, Journal of bacteriology.

Feedback regulation in the anthranilate aggregate from wild type and mutant strains of Escherichia coli.

R. Somerville, M. Pabst, J. Kuhn, 1973, The Journal of biological chemistry.

Mutational uncoupling of the transcriptional activation function of the TyrR protein of Escherichia coli K-12 from the repression function

R. Somerville, J. Cui, Jisong Cui, 1993, Journal of bacteriology.

Studies on the interaction of Trp holorepressor with several operators. Evidence that the target need not be palindromic.

G. Bogosian, R. Somerville, P. Haydock, 1983, Journal of molecular biology.

Tryptophan operon of Escherichia coli: regulatory behavior in Salmonella typhimurium cytoplasm.

R. Somerville, 1966, Science.

Direct selection and analysis of mutational events which diminish the level of expression of the trp operon

R. Somerville, J. Andrews, 1980, Journal of bacteriology.

Amino acids : biosynthesis and genetic regulation

K. Herrmann, R. Somerville, 1983 .

Expression, purification, and functional analysis of the TyrR protein of Haemophilus influenzae.

Shimin Zhao, Qin Zhu, R. Somerville, 1997, Protein expression and purification.

(Z)-3-fluorophosphoenolpyruvate as a pseudosubstrate of EPSP synthase : enzymatic synthesis of a stable fluoro analog of the calalytic intermediate

R. Somerville, J. Sikorski, C. Jones, 1992 .

An amino acid switch (Gly281-->Arg) within the "hinge" region of the tryptophan synthase beta subunit creates a novel cleavage site for the OmpT protease and selectively diminishes affinity toward a specific monoclonal antibody.

R. Somerville, G. Zhao, 1993, The Journal of biological chemistry.