M. Fisher

发表

(2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: a potent, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.

G. Scapin, N. Thornberry, R. S. Roy, 2005, Journal of medicinal chemistry.

Avermectins. Structure determination

A. W. Douglas, Jack L. Smith, M. Fisher, 1981 .

22, 23--dihydroavermectin B1, a new broad-spectrum antiparasitic agent.

L. S. Blair, W. Campbell, J. Egerton, 1980, The British veterinary journal.

SYNTHESIS OF 2-ARYLTRYPTAMINES WITH PALLADIUM CATALYZED CROSS-COUPLING OF 2-BROMOTRYPTAMINES AND ARYLBORONIC ACIDS

L. Chu, M. Fisher, M. Wyvratt, 1997 .

The chemistry and pharmacology of avermectins.

M. Fisher, H. Mrozik, Michael H. Fisher, 1992, Annual review of pharmacology and toxicology.

Synthesis and SAR of 1,2-trans-(1-hydroxy-3-phenylprop-1-yl)cyclopentane carboxamide derivatives, a new class of sodium channel blockers.

M. Fisher, K. Lyons, M. Wyvratt, 2006, Bioorganic & medicinal chemistry letters.

Broad spectrum antiprotozoal agents that inhibit histone deacetylase: structure-activity relationships of apicidin. Part 2.

D. Schmatz, R. Myers, M. Fisher, 2001, Bioorganic & medicinal chemistry letters.

Synthesis of side chain modified apicidin derivatives: potent mechanism-based histone deacetylase inhibitors

D. Schmatz, R. Myers, M. Fisher, 2000 .

Design and synthesis of histone deacetylase inhibitors: the development of apicidin transition state analogs

D. Schmatz, R. Myers, M. Fisher, 2000 .

Tryptophan-replacement and indole-modified apicidins: synthesis of potent and selective antiprotozoal agents

M. Fisher, M. Wyvratt, P. Meinke, 2000 .

2-(3,5-Dimethylphenyl)tryptamine derivatives that bind to the GnRH receptor.

M. Fisher, M. Wyvratt, Y. Yang, 2001, Bioorganic & medicinal chemistry letters.

Ivermectin, a new broad-spectrum antiparasitic agent.

W. Campbell, J. Egerton, M. Fisher, 1980, Journal of medicinal chemistry.

L-750355, a human beta3-adrenoceptor agonist; in vitro pharmacology and profile of activity in vivo in the rhesus monkey.

C. Strader, T. Bach, M. Fisher, 2000, European journal of pharmacology.

A selective human beta3 adrenergic receptor agonist increases metabolic rate in rhesus monkeys.

R. Miller, C. Strader, J. Metzger, 1998, The Journal of clinical investigation.

Substituted oxazole benzenesulfonamides as potent human beta3 adrenergic receptor agonists.

C. Strader, D. Macintyre, M. Forrest, 2000, Bioorganic & medicinal chemistry letters.

Discovery of L-755,507: A subnanomolar human β3 adrenergic receptor agonist

C. Strader, M. Fisher, M. Wyvratt, 1998 .

Human beta3 adrenergic receptor agonists containing cyclic ureidobenzenesulfonamides.

R. Miller, C. Strader, D. Macintyre, 1999, Bioorganic & medicinal chemistry letters.

Discovery of an orally bioavailable alkyl oxadiazole beta3 adrenergic receptor agonist.

R. Miller, C. Strader, D. Macintyre, 2000, Bioorganic & medicinal chemistry letters.

Human beta3 adrenergic receptor agonists containing cyanoguanidine and nitroethylenediamine moieties.

M. Fisher, M. Wyvratt, A. Weber, 2001, Bioorganic & medicinal chemistry letters.

Potent, elective human beta3 adrenergic receptor agonists containing a substituted indoline-5-sulfonamide pharmacophore.

C. Strader, M. Fisher, M. Wyvratt, 1999, Bioorganic & medicinal chemistry letters.

L-770,644: a potent and selective human beta3 adrenergic receptor agonist with improved oral bioavailability.

R. Miller, C. Strader, D. Macintyre, 1999, Bioorganic & medicinal chemistry letters.

Discovery of a potent, orally bioavailable beta(3) adrenergic receptor agonist, (R)-N-[4-[2-[[2-hydroxy-2-(3-pyridinyl)ethyl]amino]ethyl]phenyl]-4-[4 -[4-(trifluoromethyl)phenyl]thiazol-2-yl]benzenesulfonamide.

R. Miller, D. Macintyre, M. Forrest, 2000, Journal of medicinal chemistry.

Tetrahydroisoquinoline derivatives containing a benzenesulfonamide moiety as potent, selective human beta3 adrenergic receptor agonists.

M. Fisher, M. Wyvratt, A. Weber, 2000, Bioorganic & medicinal chemistry letters.

Heterocyclic derivatives of 2-(3,5-dimethylphenyl)tryptamine as GnRH receptor antagonists.

M. Fisher, M. Wyvratt, Y. Yang, 2001, Bioorganic & medicinal chemistry letters.

Human beta3-adrenergic receptor agonists containing 1,2,3-triazole-substituted benzenesulfonamides.

D. Macintyre, M. Forrest, M. Fisher, 2000, Bioorganic & medicinal chemistry letters.

Beta(3)-adrenoceptor agonist-induced increases in lipolysis, metabolic rate, facial flushing, and reflex tachycardia in anesthetized rhesus monkeys.

J. Metzger, D. Macintyre, M. Forrest, 2001, The Journal of pharmacology and experimental therapeutics.

Potent, selective benzenesulfonamide agonists of the human beta 3 adrenergic receptor.

C. Strader, M. Fisher, M. Wyvratt, 1998, Bioorganic & medicinal chemistry letters.

3-Pyridyloxypropanolamine agonists of the beta 3 adrenergic receptor with improved pharmacokinetic properties.

R. Miller, C. Strader, D. Macintyre, 1998, Bioorganic & medicinal chemistry letters.

Modulation of pulsatile GH release through a novel receptor in hypothalamus and pituitary gland.

J. P. Arena, S. Pong, A. Patchett, 1996, Recent progress in hormone research.

Discovery of potent and use-dependent sodium channel blockers for treatment of chronic pain.

Jun Liang, J. W. Tarpley, M. Fisher, 2005, Bioorganic & medicinal chemistry letters.

Substituted biaryl pyrazoles as sodium channel blockers.

V. Warren, Sanjeev Kumar, M. Fisher, 2010, Bioorganic & medicinal chemistry letters.

Discovery of a novel class of biphenyl pyrazole sodium channel blockers for treatment of neuropathic pain.

V. Warren, Sanjeev Kumar, M. Fisher, 2010, Bioorganic & medicinal chemistry letters.

Discovery of potent and use-dependent sodium channel blockers for treatment of chronic pain.

Jun Liang, J. W. Tarpley, M. Fisher, 2005, Bioorganic & medicinal chemistry letters.

A potent, orally bioavailable benzazepinone growth hormone secretagogue.

R. DeVita, M. Fisher, G. Hickey, 1998, Journal of medicinal chemistry.

Effects of acute and repeated intravenous administration of L-692,585, a novel non-peptidyl growth hormone secretagogue, on plasma growth hormone, IGF-1, ACTH, cortisol, prolactin, insulin, and thyroxine levels in beagles.

J. Taylor, D. Krupa, M. Fisher, 1994, The Journal of endocrinology.

Benzyl vinylogous amide substituted aryldihydropyridazinones and aryldimethylpyrazolones as potent and selective PDE3B inhibitors.

M. Tota, J. Metzger, M. Forrest, 2003, Bioorganic & medicinal chemistry letters.

A novel 3-substituted benzazepinone growth hormone secretagogue (L-692,429).

M. Fisher, M. Wyvratt, R. Ball, 1994, Journal of medicinal chemistry.

Aliphatic replacements of the biphenyl moiety of the nonpeptidyl growth hormone secretagogues L-692,429 and L-692,585

L. Chu, Roy G. Smith, M. Fisher, 1995 .

A Novel 3‐Substituted Benzazepinone Growth Hormone Secretagogue (L‐692, 429) (IX).

M. Fisher, M. Wyvratt, R. Ball, 1994 .

Synthesis and biological activity of imidazopyridine anticoccidial agents: Part II.

D. Schmatz, P. Liberator, M. Fisher, 2007, European journal of medicinal chemistry.

Antihypertensive activity of some novel pyridinylidene arylurea derivatives in spontaneously hypertensive rats

M. Fisher, W. V. Ruyle, E. Ulm, 1979, Experientia.

Heterocyclic analogs of the benzolactam nucleus of the non-peptidic growth hormone secretagogue L-692,429

R. DeVita, Roy G. Smith, M. Fisher, 1995 .

Peptidomimetic regulation of growth hormone secretion.

Roy G. Smith, L. V. D. van der Ploeg, A. Howard, 1997, Endocrine reviews.

Structure-activity relationships of the non-peptidyl growth hormone secretagogue L-692,429

R. DeVita, Roy G. Smith, M. Fisher, 1994 .

BENZOLACTAM GROWTH HORMONE SECRETAGOGUES : CARBOXAMIDES AS REPLACEMENTS FOR THE 2'-TETRAZOLE MOIETY OF L-692,429

R. DeVita, Roy G. Smith, M. Fisher, 1994 .

Benzolactam growth hormone secretagogues: replacements for the 2′-tetrazole moiety of L-692,429

R. DeVita, Roy G. Smith, M. Fisher, 1994 .

Structure-activity relationships in the amino acid sidechain of L-692,429

R. DeVita, Roy G. Smith, M. Fisher, 1994 .

Imidazo(1,2-a)pyridine anthelmintic and antifungal agents.

M. Fisher, A. Lusi, 1972, Journal of medicinal chemistry.

Characterization of a novel inhibitor of human DNA polymerases: 3,4,5-tri-O-galloylquinic acid.

Y. Cheng, K. Lee, M. Fisher, 1989, Biochemical pharmacology.

The structure of palasonin

M. Fisher, R. Bochis, 1968 .

Synthesis of nodulisporic acid 2' '-oxazoles and 2' '-thiazoles.

D. Schmatz, R. Berger, M. Fisher, 2001, Organic letters.

Synthesis and SAR studies of very potent imidazopyridine antiprotozoal agents.

D. Schmatz, P. Liberator, M. Fisher, 2006, Bioorganic & medicinal chemistry letters.

Brine shrimp (Artemia salina) as a convenient bioassay for avermectin analogs.

M. Fisher, H. Mrozik, T. Blizzard, 1989, The Journal of antibiotics.

Synthesis and biological activity of anticoccidial agents: 5,6-diarylimidazo[2,1-b][1,3]thiazoles.

D. Schmatz, P. Liberator, M. Fisher, 2008, Bioorganic & medicinal chemistry letters.

Discovery of a novel class of benzazepinone Na(v)1.7 blockers: potential treatments for neuropathic pain.

D. Macintyre, V. Warren, M. Fisher, 2007, Bioorganic & medicinal chemistry letters.

Chapter 16. Veterinary Drugs

M. Fisher, J. C. Chabala, H. Mrozik, 1981 .

Broad spectrum antiprotozoal agents that inhibit histone deacetylase: structure-activity relationships of apicidin. Part 1.

D. Schmatz, R. Myers, M. Fisher, 2001, Bioorganic & medicinal chemistry letters.

N-alkyl-4-piperidinyl-2,3-diarylpyrrole derivatives with heterocyclic substitutions as potent and broad spectrum anticoccidial agents.

D. Schmatz, P. Liberator, M. Fisher, 2008, Bioorganic & medicinal chemistry letters.

Identification and initial structure-activity relationships of a novel non-peptide quinolone GnRH receptor antagonist.

R G Smith, R. DeVita, M. Fisher, 1999, Bioorganic & medicinal chemistry letters.

Synthesis of avermectin B1-4″,4″a-oxide: a precursor of potent anthelmintic agents

M. Fisher, P. Meinke, B. Arison, 1992 .

Anthelmintic dihydroquinoxalino[2,3-b]quinoxalines.

J. Egerton, M. Fisher, A. Lusi, 1977, Journal of pharmaceutical sciences.

BEHAVIORAL STIMULANTS. 4-OXAZOLIDINONES.

M. Fisher, J. Bicking, S. Kwong, 1965, Journal of medicinal chemistry.

Avermectins and Milbemycins

M. Fisher, H. Mrozik, T. Blizzard, 1990 .

Syntheses and biological activities of 13-substituted avermectin aglycons.

J. Schaeffer, M. Fisher, P. Eskola, 1989, Journal of medicinal chemistry.

AVERMECTINS. STRUCTURE DETERMINATION

A. W. Douglas, Jack L. Smith, M. Fisher, 1981 .

THERMAL REARRANGEMENT OF THE IMMUNOSUPPRESSANT FK-506

M. Fisher, M. Wyvratt, B. Arison, 1990 .

Acyclic structural variants of growth hormone secretagogue L-692,429.

M. Fisher, M. Wyvratt, R. Smith, 1999, Bioorganic & medicinal chemistry letters.

Chemical degradation of avermectin B1

M. Fisher, H. Mrozik, T. Blizzard, 1988 .

Synthesis of an avermectin-nemadectin hybrid.

M. Fisher, H. Mrozik, T. Shih, 1991 .

Combined modalities of resistance in etoposide-resistant human KB cell lines.

Y. Cheng, P. Ferguson, M. Fisher, 1988, Cancer research.

Synthesis and SAR of benzyl and phenoxymethylene oxadiazole benzenesulfonamides as selective beta3 adrenergic receptor agonist antiobesity agents.

C. Strader, D. Macintyre, M. Forrest, 2000, Bioorganic & medicinal chemistry letters.

SAR studies of novel 5-substituted 2-arylindoles as nonpeptidyl GnRH receptor antagonists.

L. Chu, M. Fisher, M. Wyvratt, 2001, Bioorganic & medicinal chemistry letters.

Initial structure-activity relationship of a novel class of nonpeptidyl GnRH receptor antagonists: 2-arylindoles.

R G Smith, L. Chu, M. Fisher, 2001, Bioorganic & medicinal chemistry letters.

Potent antagonists of gonadotropin releasing hormone receptors derived from quinolone-6-carboxamides.

R. DeVita, F. Ujjainwalla, M. Fisher, 2000, Bioorganic & medicinal chemistry letters.

Investigation of the 4-O-alkylamine substituent of non-peptide quinolone GnRH receptor antagonists.

R. DeVita, M. Fisher, M. Wyvratt, 1999, Bioorganic & medicinal chemistry letters.

Avermectin analogs with a spacer between the aglycone and the disaccharide

M. Fisher, H. Mrozik, T. Blizzard, 1991 .

Mercuric acetate oxidation of avermectin A2a as a route to the selective cleavage of the allylic C-5-methoxy group

M. Fisher, P. Eskola, H. Mrozik, 1986 .

Chemical modification of paraherquamide. 1. Unusual reactions and absolute stereochemistry

J. Springer, M. Fisher, H. Mrozik, 1989 .

Nodulisporic acid side-chain modifications: access to the 2", 3", 4", and 6" registers.

D. Schmatz, M. Fisher, M. Wyvratt, 2003, Bioorganic & medicinal chemistry letters.

Synthesis of 13-epi-22,23-dihydroavermectin B1 aglycon

M. Fisher, H. Mrozik, T. K. Jones, 1992 .

Chemical modification of paraherquamide. 3. Vinyl ether modified analogs

J. Schaeffer, M. Fisher, H. Mrozik, 1991 .

Chemical Modification of Paraherquamide. 4. 1-N-substituted analogs

J. Schaeffer, M. Fisher, H. Mrozik, 1991 .

Chemical modification of paraherquamide. 2. Replacement of the C-14 methyl group

J. Schaeffer, M. Fisher, H. Mrozik, 1990 .

Structure and activity of avermectins and milbemycins in animal health.

M. Fisher, H. Mrozik, W. Shoop, 1995, Veterinary parasitology.

The Discovery of Ivermectin and Other Avermectins

W. Campbell, M. Fisher, R. W. Burg, 1984 .

Ivermectin: a potent new antiparasitic agent.

W. Campbell, M. Fisher, E. Stapley, 1983, Science.

Chapter 14. Antiparasitic Agents

C. Wang, M. Fisher, 1978 .

Anthelmintic 2-arylhydrazino- and 2-arylazo-2-thiazolines.

A. Patchett, J. Egerton, M. Fisher, 1977, Journal of pharmaceutical sciences.

Anticoccidial 1-substituted 4(1H)-pyridinone hydrazones.

A. W. Douglas, P. Gund, A. Patchett, 1977, Journal of medicinal chemistry.

Eprinomectin: a novel avermectin for use as a topical endectocide for cattle.

W. Campbell, R. Seward, M. Turner, 1996, International journal for parasitology.

Synthesis of side chain truncated 3"-aldehyde, 3"-carboxylic acid, and 1"-aldehyde from nodulisporic acid A.

M. Fisher, M. Wyvratt, P. Meinke, 2002, Organic letters.

SYSTEMIC EFFICACY OF NODULISPORAMIDES AGAINST FLEAS ON DOGS

D. Schmatz, B. Pikounis, M. Fisher, 2001, The Journal of parasitology.

Side-chain homologation of nodulisporic acid: synthesis of potent new dienyl derivatives.

D. Schmatz, M. Fisher, M. Wyvratt, 2002, Bioorganic & medicinal chemistry letters.

Chemical modification of nodulisporic acid A: preliminary structure-activity relationships.

D. Schmatz, T. Shih, M. Fisher, 2000, Bioorganic & medicinal chemistry letters.

Chapter 15. Antiparasitic Agents

C. Wang, M. Fisher, 1977 .

Chemistry of A nti nematoda I Agents

M. Fisher, 1986 .

Chemistry of Antinematodal Agents

M. Fisher, 1986 .

Improved syntheses of fluorinated tertiary butylamines

M. Fisher, M. Wyvratt, P. Meinke, 1999 .

Synthesis and SAR studies of potent imidazopyridine anticoccidial agents.

D. Schmatz, P. Liberator, M. Fisher, 2007, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of 2-(4-fluorophenyl)-3-pyrimidin-4-ylimidazo[1,2-a]pyridine derivatives as anticoccidial agents.

D. Schmatz, P. Liberator, M. Fisher, 2006, Bioorganic & medicinal chemistry letters.

Anti-herpes simplex virus activity of 5-substituted 2-pyrimidinone nucleosides

Y. Cheng, M. Fisher, S. Efange, 1989, Antimicrobial Agents and Chemotherapy.

Synthesis of milbemycins from avermectins

M. Fisher, J. C. Chabala, P. Eskola, 1983 .

Partial syntheses of avermectin Bla and ivermectin from avermectin B2a

M. Fisher, P. Eskola, H. Mrozik, 1982 .

Synthesis of ring-contracted, 25-nor-6,5-spiroketal-modified avermectin derivatives

M. Fisher, P. Meinke, H. Mrozik, 1992 .

Hydroxylated N-alkyl-4-piperidinyl-2,3-diarylpyrrole derivatives as potent broad-spectrum anticoccidial agents.

D. Schmatz, P. Liberator, M. Fisher, 2005, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of 2,3-diarylpyrrole inhibitors of parasite cGMP-dependent protein kinase as novel anticoccidial agents.

D. Schmatz, P. Liberator, M. Fisher, 2005, Bioorganic & medicinal chemistry letters.

5,11-dimethyl-2,9-bis(phenylacetyl)-5,11-diazatetracyclo[6.2.2.0(2,7).0(4,9)]dodecane, a potent, novel analgesic.

A. Patchett, M. Fisher, E. Grabowski, 1977, Journal of medicinal chemistry.

3-Pyridylethanolamines: potent and selective human beta 3 adrenergic receptor agonists.

C. Strader, D. Macintyre, M. Forrest, 1998, Bioorganic & medicinal chemistry letters.

Avermectin acyl derivatives with anthelmintic activity.

J. Egerton, M. Fisher, P. Eskola, 1982, Journal of medicinal chemistry.

Synthesis and SAR studies of diarylpyrrole anticoccidial agents.

D. Schmatz, P. Liberator, M. Fisher, 2006, Bioorganic & medicinal chemistry letters.

Stimulation of growth hormone release from rat primary pituitary cells by L-692,429, a novel non-peptidyl GH secretagogue.

M. Fisher, M. Wyvratt, R. Smith, 1993, Endocrinology.

IVERMECTIN, A NEW BROAD-SPECTRUM ANTIPARASITIC AGENT

W. Campbell, J. Egerton, M. Fisher, 1981 .

THE CHEMISTRY AND PHARMACOLOGY OF A VERMECTINS

M. Fisher, H. Mrozik, 1992 .

Discovery of the development candidate N-tert-butyl nodulisporamide: a safe and efficacious once monthly oral agent for the control of fleas and ticks on companion animals.

Pierre Demontigny, D. Schmatz, M. Fisher, 2009, Journal of medicinal chemistry.

Efficacy in sheep and pharmacokinetics in cattle that led to the selection of eprinomectin as a topical endectocide for cattle.

M. Turner, J. Egerton, M. Fisher, 1996, International journal for parasitology.

Discovery of potent and selective dipeptidyl peptidase IV inhibitors derived from beta-aminoamides bearing subsituted triazolopiperazines.

G. Scapin, N. Thornberry, R. S. Roy, 2008, Journal of medicinal chemistry.

NITRO- AND AMINO-IMIDAZOLESULPHONAMIDES

M. Fisher, R. S. Stuart, W. Nicholson, 1961 .

A convenient synthesis of 6‐azaindole

M. Fisher, A. Matzuk, 1969 .

1-(Substituted)benzyl-5-aminoimidazole-4-carboxamides are potent orally active inhibitors ofTrypanosoma cruzi in mice

A. Patchett, M. Fisher, M. Wyvratt, 1991, Experientia.

Activity of the new antifolate N10-propargyl-5,8-dideazafolate and its polyglutamates against human dihydrofolate reductase, human thymidylate synthetase, and KB cells containing different levels of dihydrofolate reductase.

Y. Cheng, M. Fisher, M. G. Nair, 1985, Cancer research.

Structure—Activity Relationships of the Avermectins and Milbemycins

M. Fisher, 1997 .

4 -DEOXY-4 -AMINOAVERMECTINS WITH POTENT BROAD SPECTRUM ANTIPARASITIC ACTIVITIES

J. Egerton, M. Fisher, M. Wyvratt, 1995 .

Synthesis of 1,19-Aza-1,19-desoxy-avermectin B(1a): The First Avermectin Macrolactam.

M. Fisher, P. Meinke, B. Arison, 1998, The Journal of organic chemistry.

Synthesis of apicidin-derived quinolone derivatives: parasite-selective histone deacetylase inhibitors and antiproliferative agents.

D. Schmatz, R. Myers, M. Fisher, 2000, Journal of medicinal chemistry.

Human beta3 adrenergic receptor agonists containing imidazolidinone and imidazolone benzenesulfonamides.

C. Strader, D. Macintyre, M. Forrest, 1999, Bioorganic & medicinal chemistry letters.

Discovery of novel avermectins with unprecedented insecticidal activity

M. Fisher, M. Wyvratt, P. Eskola, 1989, Experientia.

Synthesis and biological activity of imidazopyridine anticoccidial agents: part I.

D. Schmatz, P. Liberator, M. Fisher, 2007, European journal of medicinal chemistry.

Benzolactam growth hormone secretagogues: Replacement of the C-3 amide bond in L-692,429

Roy G. Smith, M. Fisher, M. Wyvratt, 1996 .

IMIDAZOLE SULPHONAMIDES AND RELATED COMPOUNDS

M. Fisher, R. S. Stuart, W. Nicholson, 1961 .

Synthesis and biological activity of anticoccidial agents: 2,3-diarylindoles.

D. Schmatz, P. Liberator, M. Fisher, 2009, Bioorganic & Medicinal Chemistry Letters.

Avermectins and milbemycins against Fasciola hepatica: in vivo drug efficacy and in vitro receptor binding.

M. Fisher, H. Mrozik, D. A. Ostlind, 1995, International Journal of Parasitology.

Potent antagonists of gonadotropin releasing hormone receptors derived from quinolone-6-carboxamides.

R. DeVita, F. Ujjainwalla, M. Fisher, 2000, Bioorganic & medicinal chemistry letters.

Isomeric phenylthioimidazo[1,2-alpha]pyridines as anthelmintics.

M. Fisher, R. Reamer, L. Olen, 1981, Journal of medicinal chemistry.

ISOMERIC PHENYLTHIOIMIDAZO(1,2-A)PYRIDINES AS ANTHELMINTICS

M. Fisher, R. Reamer, L. Olen, 1982 .

An unusual twist in the synthesis and hydrolysis of the 23,24-epoxide of 22,23-dihydroavermectin B1a

M. Fisher, H. Mrozik, G. Doss, 1992 .

Affinity probes for the avermectin binding proteins.

J. Schaeffer, M. Fisher, P. Meinke, 1992, Journal of medicinal chemistry.

Antiparasitic Agents, Avermectins

M. Fisher, H. Mrozik, 2000 .

Avermectin B1-8,9-oxide: reactivity, bioactivity, and stereochemistry.

M. Fisher, H. Mrozik, T. Blizzard, 1993 .

Reactivity of an epoxy-spiroketal within avermectin B2a

M. Fisher, H. Mrozik, R. Newbold, 1993 .

Synthesis, reactivity, and bioactivity of avermectin B1-3,4-oxide

M. Fisher, H. Mrozik, T. Blizzard, 1990 .

Substituted biaryl oxazoles, imidazoles, and thiazoles as sodium channel blockers.

V. Warren, Sanjeev Kumar, M. Fisher, 2010, Bioorganic & medicinal chemistry letters.

Improved Syntheses of Fluorinated Tertiary Butylamines.

M. Fisher, M. Wyvratt, P. Meinke, 1999 .

3-Amino-1,5-benzodiazepinones: potent, state-dependent sodium channel blockers with anti-epileptic activity.

V. Warren, M. Fisher, K. Lyons, 2008, Bioorganic & medicinal chemistry letters.

Novel cyclopentane dicarboxamide sodium channel blockers as a potential treatment for chronic pain.

M. Fisher, K. Lyons, M. Wyvratt, 2005, Bioorganic & medicinal chemistry letters.

Discovery of potent and selective dipeptidyl peptidase IV inhibitors derived from beta-aminoamides bearing subsituted triazolopiperazines.

G. Scapin, N. Thornberry, R. S. Roy, 2008, Journal of medicinal chemistry.

Discovery of L-755,507: a subnanomolar human beta 3 adrenergic receptor agonist.

C. Strader, M. Fisher, M. Wyvratt, 1998, Bioorganic & medicinal chemistry letters.