Jide Tian

发表

Long-term monitoring of transplanted islets using positron emission tomography.

S. Gambhir, M. Atkinson, Yuxin Lu, 2006, Molecular therapy : the journal of the American Society of Gene Therapy.

Increased risk for T cell autoreactivity to ß-cell antigens in the mice expressing the Avy obesity-associated gene

R. Sun, Ting-Ting Wu, M. Atkinson, 2019, Scientific Reports.

Infectious Th1 and Th2 autoimmunity in diabetes‐prone mice

Blake Middleton, Jide Tian, D. Kaufman, 1998, Immunological reviews.

Autoimmune Disease Progression Attenuation of Inducible Th2 Immunity with

Jide Tian, D. Kaufman, 1998 .

Oral Treatment with γ-Aminobutyric Acid Improves Glucose Tolerance and Insulin Sensitivity by Inhibiting Inflammation in High Fat Diet-Fed Mice

Jide Tian, D. Kaufman, Jing Yong, 2011, PloS one.

Novel Derivative of Bardoxolone Methyl Improves Safety for the Treatment of Diabetic Nephropathy.

Ping Li, Xiaojun Xu, Jide Tian, 2017, Journal of medicinal chemistry.

Synthesis and biological evaluation of nitric oxide-releasing derivatives of oleanolic acid as inhibitors of HepG2 cell apoptosis.

Jide Tian, Yihua Zhang, S. Peng, 2007, Bioorganic & medicinal chemistry letters.

Homotaurine limits the spreading of T cell autoreactivity within the CNS and ameliorates disease in a model of multiple sclerosis

Jide Tian, D. Kaufman, Min Song, 2021, Scientific Reports.

Homotaurine, a safe blood-brain barrier permeable GABAA-R-specific agonist, ameliorates disease in mouse models of multiple sclerosis

R. Olsen, Jide Tian, D. Kaufman, 2018, Scientific Reports.

Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

A. Tobin, E. Sercarz, M. Atkinson, 1993, Nature.

Oral GABA treatment downregulates inflammatory responses in a mouse model of rheumatoid arthritis

Jide Tian, D. Kaufman, Jing Yong, 2011, Autoimmunity.

Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes–prone mice

A. Tobin, N. Sarvetnick, M. Atkinson, 1996, Nature Medicine.

GABA Administration Ameliorates Sjogren’s Syndrome in Two Different Mouse Models

Blake Middleton, Jide Tian, D. Kaufman, 2022, Biomedicines.

GABAA-Receptor Agonists Limit Pneumonitis and Death in Murine Coronavirus-Infected Mice

Blake Middleton, Jide Tian, D. Kaufman, 2021, Viruses.

GABA administration limits viral replication and pneumonitis in a mouse model of COVID-19

Blake Middleton, Jide Tian, D. Kaufman, 2021, bioRxiv.

GABAB-Receptor Agonist-Based Immunotherapy for Type 1 Diabetes in NOD Mice

Haoyuan Liu, Blake Middleton, Jide Tian, 2021, Biomedicines.

GABA administration prevents severe illness and death following coronavirus infection in mice

Blake Middleton, Jide Tian, D. Kaufman, 2020, bioRxiv : the preprint server for biology.

A Clinically Applicable Positive Allosteric Modulator of GABA Receptors Promotes Human β-Cell Replication and Survival as well as GABA's Ability to Inhibit Inflammatory T Cells

Jide Tian, D. Kaufman, H. Dang, 2019, Journal of diabetes research.

Homotaurine Treatment Enhances CD4+ and CD8+ Regulatory T Cell Responses and Synergizes with Low-Dose Anti-CD3 to Enhance Diabetes Remission in Type 1 Diabetic Mice

Jide Tian, D. Kaufman, H. Dang, 2019, ImmunoHorizons.

Combined Therapy With GABA and Proinsulin/Alum Acts Synergistically to Restore Long-term Normoglycemia by Modulating T-Cell Autoimmunity and Promoting β-Cell Replication in Newly Diabetic NOD Mice

Jide Tian, D. Kaufman, H. Dang, 2014, Diabetes.

γ-Aminobutyric Acid Regulates Both the Survival and Replication of Human β-Cells

M. Atkinson, Yi-Ping Jin, Jide Tian, 2013, Diabetes.

Short running title: GABA regulates ßcell survival and replication

M. Atkinson, Yi-Ping Jin, Jide Tian, 2013 .

Combining Antigen-Based Therapy with GABA Treatment Synergistically Prolongs Survival of Transplanted ß-Cells in Diabetic NOD Mice

Jide Tian, D. Kaufman, H. Dang, 2011, PloS one.

Novel nitric oxide-releasing derivatives of farnesylthiosalicylic acid: synthesis and evaluation of antihepatocellular carcinoma activity.

Yong Ling, Jide Tian, Yihua Zhang, 2011, Journal of medicinal chemistry.

GABAA receptors mediate inhibition of T cell responses

T. Hales, Jide Tian, D. Kaufman, 1999, Journal of Neuroimmunology.

Transgenically Induced GAD Tolerance Curtails the Development of Early β-Cell Autoreactivities but Causes the Subsequent Development of Supernormal Autoreactivities to Other β-Cell Antigens

Jide Tian, D. Kaufman, H. Dang, 2009, Diabetes.

A salen-manganese catalytic free radical scavenger inhibits type 1 diabetes and islet allograft rejection.

L. Ignarro, G. Tocco, Jide Tian, 2004, Diabetes.

g -Aminobutyric Acid Regulates Both the Survival and Replication of Human b -Cells

Jide Tian, D. Kaufman, H. Dang, 2013 .

Selective Deletion of Pten in Pancreatic β Cells Leads to Increased Islet Mass and Resistance to STZ-Induced Diabetes

B. Stiles, Hong Wu, M. Magnuson, 2006, Molecular and Cellular Biology.

Discovery of a potential anti-ischemic stroke agent: 3-pentylbenzo[c]thiophen-1(3H)-one.

Jing Wu, Jide Tian, Yihua Zhang, 2012, Journal of medicinal chemistry.

WB1106, a novel nitric oxide-releasing derivative of telmisartan, inhibits hypertension and improves glucose metabolism in rats.

Jide Tian, H. Ji, Yi-hua Zhang, 2007, European journal of pharmacology.

Memory and effector T cells modulate subsequently primed immune responses to unrelated antigens.

Yuxin Lu, Jide Tian, D. Kaufman, 2003, Cellular immunology.

Precocious Development of Autoimmunity Antigen-Based Immunotherapy Drives the

Jide Tian, D. Kaufman, A. Olcott, 2002 .

Antigen-Based Immunotherapy Drives the Precocious Development of Autoimmunity1

Jide Tian, D. Kaufman, A. Olcott, 2002, The Journal of Immunology.

Lipopolysaccharide-Activated B Cells Down-Regulate Th1 Immunity and Prevent Autoimmune Diabetes in Nonobese Diabetic Mice1

Yuxin Lu, Jide Tian, D. Kaufman, 2001, The Journal of Immunology.

B Cells Are Crucial for Determinant Spreading of T Cell Autoimmunity among β Cell Antigens in Diabetes-Prone Nonobese Diabetic Mice1

Yuxin Lu, Jide Tian, D. Kaufman, 2006, The Journal of Immunology.

MiceAutoimmune Diabetes in Nonobese Diabetic Down-Regulate Th1 Immunity and Prevent Lipopolysaccharide-Activated B Cells

Yuxin Lu, Jide Tian, D. Kaufman, 2001 .

Potent Inhibition of Nitric Oxide-Releasing Bifendate Derivatives against Drug-Resistant K562/A02 Cells in Vitro and in Vivo.

Hui Peng, Xiaobo Tang, Jide Tian, 2017, Journal of medicinal chemistry.

Repurposing Lesogaberan to Promote Human Islet Cell Survival and β-Cell Replication

Jide Tian, D. Kaufman, H. Dang, 2017, Journal of diabetes research.

vaccine-induced neuroprotection in a mouse model of Parkinson's disease.

C. Wasserfall, Blake Middleton, Jide Tian, 2011 .

is associated with regulatory T-cell induction in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.

M. Horwitz, Blake Middleton, Jide Tian, 2013 .

Designing Personalized Antigen-Specific Immunotherapies for Autoimmune Diseases—The Case for Using Ignored Target Cell Antigen Determinants

Jide Tian, D. Kaufman, Min Song, 2022, Cells.

Antigen-Based Therapies Using Ignored Determinants of β Cell Antigens Can More Effectively Inhibit Late-Stage Autoimmune Disease in Diabetes-Prone Mice1

L. Adorini, Blake Middleton, Jide Tian, 2005, The Journal of Immunology.

Disease in Diabetes-Prone Mice Effectively Inhibit Late-Stage Autoimmune Cell Antigens Can More b Determinants of Antigen-Based Therapies Using Ignored

L. Adorini, Blake Middleton, Jide Tian, 2005 .

The Frequency of High Avidity T Cells Determines the Hierarchy of Determinant Spreading1

L. Adorini, Jide Tian, D. Kaufman, 2001, The Journal of Immunology.

Spreading Determines the Hierarchy of Determinant The Frequency of High Avidity T Cells

L. Adorini, Jide Tian, D. Kaufman, 2001 .

Discovery of New Monocarbonyl Ligustrazine-Curcumin Hybrids for Intervention of Drug-Sensitive and Drug-Resistant Lung Cancer.

Jide Tian, Yihua Zhang, C. Ren, 2016, Journal of medicinal chemistry.

Correction to "Hybrid Molecule from O2-(2,4-Dinitrophenyl)diazeniumdiolate and Oleanolic Acid: A Glutathione S-Transferase π-Activated Nitric Oxide Prodrug with Selective Anti-Human Hepatocellular Carcinoma Activity and Improved Stability".

Jide Tian, Yihua Zhang, H. Ji, 2013, Journal of medicinal chemistry.

Multimodality Imaging of b -Cells in Mouse Models of Type I and II Diabetes

S. Gambhir, M. Namavari, M. Atkinson, 2011 .

Synthesis and biological evaluation of 3-[4-(amino/methylsulfonyl)phenyl]methylene-indolin-2-one derivatives as novel COX-1/2 and 5-LOX inhibitors.

Jide Tian, Yihua Zhang, H. Ji, 2010, Bioorganic & medicinal chemistry letters.

A GABA-receptor agonist reduces pneumonitis severity, viral load, and death rate in SARS-CoV-2-infected mice

Jide Tian, D. Kaufman, L. Comai, 2022, Frontiers in Immunology.

Novel hybrids of optically active ring-opened 3-n-butylphthalide derivative and isosorbide as potential anti-ischemic stroke agents.

Jide Tian, Lin-na Wang, Xiaoli Wang, 2013, Journal of medicinal chemistry.

Design, Synthesis, and Biological Evaluation of Organic Nitrite (NO2-) Donors as Potential Anticerebral Ischemia Agents.

Kai Huang, Xiaojun Xu, Jide Tian, 2021, Journal of medicinal chemistry.

Synthesis and biological evaluation of furoxan-based nitric oxide-releasing derivatives of glycyrrhetinic acid as anti-hepatocellular carcinoma agents.

Jide Tian, Yihua Zhang, H. Ji, 2010, Bioorganic & medicinal chemistry letters.

Antigen-Based Therapy for the Treatment of Type 1 Diabetes

Jide Tian, D. Kaufman, 2009, Diabetes.

Design, synthesis, and antihepatocellular carcinoma activity of nitric oxide releasing derivatives of oleanolic acid.

Jide Tian, D. Kaufman, Yihua Zhang, 2008, Journal of medicinal chemistry.

Synthesis and anti-human hepatocellular carcinoma activity of new nitric oxide-releasing glycosyl derivatives of oleanolic acid.

Luyong Zhang, Q. Guo, Li Zhao, 2010, Organic & biomolecular chemistry.

Synthesis and Biological Evaluation of Novel Olean-28,13β-lactams as Potential Antiprostate Cancer Agents.

Jide Tian, Yihua Zhang, H. Ji, 2015, Journal of medicinal chemistry.

Synthesis of CDDO-amino acid-nitric oxide donor trihybrids as potential antitumor agents against both drug-sensitive and drug-resistant colon cancer.

Jide Tian, Yihua Zhang, Yong Ai, 2015, Journal of medicinal chemistry.

Glycosylated diazeniumdiolate-based oleanolic acid derivatives: synthesis, in vitro and in vivo biological evaluation as anti-human hepatocellular carcinoma agents.

Jide Tian, Yihua Zhang, H. Ji, 2012, Organic & biomolecular chemistry.

Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication

Blake Middleton, Jide Tian, D. Kaufman, 2017, Scientific Reports.

Design and synthesis of the ring-opened derivative of 3-n-butylphthalide-ferulic acid-glucose trihybrids as potential anti-ischemic agents

Yunman Li, Jide Tian, W. Yin, 2020 .

Multimodality Imaging of β-Cells in Mouse Models of Type 1 and 2 Diabetes

S. Gambhir, M. Namavari, M. Atkinson, 2011, Diabetes.

Characterization of the Murine μ Opioid Receptor Gene (*)

C. Evans, Jide Tian, D. Kaufman, 1995, The Journal of Biological Chemistry.

Novel hybrids of (phenylsulfonyl)furoxan and anilinopyrimidine as potent and selective epidermal growth factor receptor inhibitors for intervention of non-small-cell lung cancer.

H. Ji, Chun Han, Jide Tian, 2013, Journal of medicinal chemistry.

Synthesis and evaluation of nitric oxide-releasing derivatives of farnesylthiosalicylic acid as anti-tumor agents.

Yong Ling, Jide Tian, Yihua Zhang, 2010, Bioorganic & medicinal chemistry.

Determinant Spreading of T Helper Cell 2 (Th2) Responses to Pancreatic Islet Autoantigens

P. Lehmann, Jide Tian, D. Kaufman, 1997, The Journal of experimental medicine.

Major histocompatibility complex class I molecules modulate embryonic neuritogenesis and neuronal polarization

Yi-Ping Jin, Blake Middleton, Jide Tian, 2012, Journal of Neuroimmunology.

BCG Vaccine-Induced Neuroprotection in a Mouse Model of Parkinson's Disease

C. Wasserfall, Blake Middleton, Jide Tian, 2011, PloS one.

A Potential Role for Shed Soluble Major Histocompatibility Class I Molecules as Modulators of Neurite Outgrowth

C. Evans, Yuxin Lu, Blake Middleton, 2011, PloS one.

Bacillus Calmette‐Guerin vaccine‐mediated neuroprotection is associated with regulatory T‐cell induction in the 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine mouse model of Parkinson's disease

M. Horwitz, Blake Middleton, Jide Tian, 2013, Journal of neuroscience research.

Hybrid molecule from O2-(2,4-dinitrophenyl)diazeniumdiolate and oleanolic acid: a glutathione S-transferase π-activated nitric oxide prodrug with selective anti-human hepatocellular carcinoma activity and improved stability.

Jide Tian, Yihua Zhang, H. Ji, 2013, Journal of medicinal chemistry.

Design and synthesis of rosiglitazone-ferulic acid-nitric oxide donor trihybrids for improving glucose tolerance.

Yunman Li, Jide Tian, Yihua Zhang, 2019, European journal of medicinal chemistry.

Neurons Preferentially Respond to Self-MHC Class I Allele Products Regardless of Peptide Presented

C. Evans, Y. Yoshimura, Yuxin Lu, 2009, The Journal of Immunology.

Bioluminescent monitoring of islet graft survival after transplantation.

Sanjiv Sam Gambhir, S. Gambhir, M. Atkinson, 2004, Molecular therapy : the journal of the American Society of Gene Therapy.

PresentedClass I Allele Products Regardless of Peptide Neurons Preferentially Respond to Self-MHC

C. Evans, Y. Yoshimura, Blake Middleton, 2009 .

γ-Aminobutyric Acid Inhibits T Cell Autoimmunity and the Development of Inflammatory Responses in a Mouse Type 1 Diabetes Model1

Hanwei Zhang, Yuxin Lu, Jide Tian, 2004, The Journal of Immunology.

The GABA and GABA-Receptor System in Inflammation, Anti-Tumor Immune Responses, and COVID-19

Jide Tian, D. Kaufman, 2023, Biomedicines.

Homotaurine, a safe blood-brain barrier permeable GABAA-R-specific agonist, ameliorates disease in mouse models of multiple sclerosis

R. Olsen, Jide Tian, D. Kaufman, 2018, Scientific Reports.

O2-3-Aminopropyl diazeniumdiolates suppress the progression of highly metastatic triple-negative breast cancer by inhibition of microvesicle formation via nitric oxide-based epigenetic regulation.

H. Xiang, Jide Tian, Yihua Zhang, 2018, Chemical science.

Major histocompatibility complex class I-mediated inhibition of neurite outgrowth from peripheral nerves.

Jide Tian, D. Kaufman, H. Dang, 2011, Immunology letters.

Enhanced neuronal expression of major histocompatibility complex class I leads to aberrations in neurodevelopment and neurorepair

Jide Tian, D. Kaufman, H. Dang, 2011, Journal of Neuroimmunology.

Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes

M. Atkinson, P. Lehmann, Jide Tian, 1996, The Journal of experimental medicine.

Noninvasive imaging of islet grafts using positron-emission tomography.

M. Phelps, S. Gambhir, M. Atkinson, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Antigen-based immunotherapy for autoimmune disease: from animal models to humans?

Jide Tian, D. Kaufman, J. Tian, 1999, Immunology today.

T cell cross-reactivity between coxsackievirus and glutamate decarboxylase is associated with a murine diabetes susceptibility allele

P. Lehmann, Jide Tian, D. Kaufman, 1994, The Journal of experimental medicine.

Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication

Blake Middleton, Jide Tian, D. Kaufman, 2017, Scientific Reports.

Attenuation of inducible Th2 immunity with autoimmune disease progression.

Jide Tian, D. Kaufman, J. Tian, 1998, Journal of immunology.

Determinant Spreading of T Helper Cell 2 (Th2) Responses to Pancreatic Islet Autoantigens

P. Lehmann, Jide Tian, D. Kaufman, 1997, The Journal of experimental medicine.