B. Winston

发表

Safety of Cell Therapy with Mesenchymal Stromal Cells (SafeCell): A Systematic Review and Meta-Analysis of Clinical Trials

J. Marshall, M. Lalu, D. Stewart, 2012, PloS one.

Evolution of ARDS biomarkers: Will metabolomics be the answer?

B. Winston, S. Metwaly, A. Côté, 2018, American journal of physiology. Lung cellular and molecular physiology.

Roles for insulin-like growth factor I and transforming growth factor-beta in fibrotic lung disease.

B. Winston, P. M. Krein, P. Krein, 2002, Chest.

Metabolomics in critical care medicine: a new approach to biomarker discovery.

H. Vogel, A. Weljie, B. Winston, 2014, Clinical and investigative medicine. Medecine clinique et experimentale.

Surrogate Humane Endpoints in Small Animal Models of Acute Lung Injury: A Modified Delphi Consensus Study of Researchers and Laboratory Animal Veterinarians.

J. Laffey, M. Lalu, D. Stewart, 2020, Critical care medicine.

Evaluating mesenchymal stem cell therapy for sepsis with preclinical meta-analyses prior to initiating a first-in-human trial

J. Marshall, D. Moher, M. Lalu, 2016, eLife.

Seasonal changes in morphology of the thyroid gland of a hibernator, Spermophilus richardsoni

B. Winston, N. E. Henderson, 1981 .

Metabolomics: Applications and Promise in Mycobacterial Disease.

M. Mirsaeidi, B. Winston, M. Banoei, 2015, Annals of the American Thoracic Society.

New Strategies and Challenges in Lung Proteomics and Metabolomics. An Official American Thoracic Society Workshop Report.

R. Bowler, M. Fessler, R. Kelly, 2017, Annals of the American Thoracic Society.

Kinetics of Serological Responses in Critically Ill Patients Hospitalized With 2009 Pandemic Influenza A(H1N1) Virus Infection in Canada, 2009–2011

D. Cook, J. Marshall, J. Rello, 2018, The Journal of infectious diseases.

NMR-based metabolomic profiling can differentiate follicular lymphoma from benign lymph node tissues and may be predictive of outcome

H. Habibi, B. Winston, M. Banoei, 2022, Scientific Reports.

Plasma lipid profiling for the prognosis of 90-day mortality, in-hospital mortality, ICU admission, and severity in bacterial community-acquired pneumonia (CAP)

H. Vogel, D. Angus, A. Weljie, 2020, Critical Care.

Adenovirus-mediated gene transfer of hIGF-IB in mouse lungs induced prolonged inflammation but no fibroproliferation.

B. Winston, G. Andonegui, A. Ni, 2010, American journal of physiology. Lung cellular and molecular physiology.

Sustained Dysregulation of the Plasma Renin-angiotensin System in Acute COVID-19

S. Murthy, F. Lamontagne, K. Walley, 2021 .

Surfactant Dysfunction in ARDS and Bronchiolitis is Repaired with Cyclodextrins.

B. Winston, Mustafa Al-Saiedy, Ryan Pratt, 2018, Military medicine.

Activation of MEKK by Formyl-methionyl-leucyl-phenylalanine in Human Neutrophils

G. Johnson, S. Young, B. Winston, 1996, The Journal of Biological Chemistry.

Preferential activation of the p46 isoform of JNK/SAPK in mouse macrophages by TNF alpha.

E. Chan, M. Wynes, D. Riches, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Interferon-γ and Transforming Growth Factor-β Modulate the Activation of Mitogen-Activated Protein Kinases and Tumor Necrosis Factor-α Production Induced by Fcγ-Receptor Stimulation in Murine Macrophages

E. Chan, D. Riches, P. Henson, 1997 .

Fc gamma receptor cross-linking activates p42, p38, and JNK/SAPK mitogen-activated protein kinases in murine macrophages: role for p42MAPK in Fc gamma receptor-stimulated TNF-alpha synthesis.

E. Chan, D. Riches, G. Johnson, 1997, Journal of immunology.

Interferon-gamma and transforming growth factor-beta modulate the activation of mitogen-activated protein kinases and tumor necrosis factor-alpha production induced by Fc gamma-receptor stimulation in murine macrophages.

E. Chan, D. Riches, P. Henson, 1997, Biochemical and biophysical research communications.

Localization of insulin-like growth factor-I in lung tissues of patients with fibroproliferative acute respiratory distress syndrome.

F. Green, B. Winston, P. M. Krein, 2003, American journal of respiratory and critical care medicine.

Characterization of IFN-gamma regulation of the complement factor B gene in macrophages.

Y. Huang, B. Winston, P. M. Krein, 2001, European journal of immunology.

Exploratory Evaluation of the Relationship Between iNKT Cells and Systemic Cytokine Profiles of Critically Ill Patients with Neurological Injury

C. Doig, D. Zygun, P. Kubes, 2021, Neurocritical Care.

Sequential expression of IGF-IB followed by active TGF-β1 induces synergistic pulmonary fibroproliferation in vivo.

B. Winston, M. Kelly, G. Andonegui, 2012, American journal of physiology. Lung cellular and molecular physiology.

Activation of p38mapk, MKK3, and MKK4 by TNF-alpha in mouse bone marrow-derived macrophages.

E. Chan, D. Riches, G. Johnson, 1997, Journal of immunology.

Systems Biology ARDS Research with a Focus on Metabolomics

B. Winston, S. Metwaly, Sayed Metwaly, 2020, Metabolites.

Akt/Protein Kinase B Activation by Adenovirus Vectors Contributes to NFκB-Dependent CXCL10 Expression

Qiang Liu, B. Winston, D. Muruve, 2005, Journal of Virology.

INSULIN-LIKE GROWTH FACTORS

R. Arora, B. Winston, A. Ni, 2006 .

Cytokine-induced macrophage differentiation: a tale of 2 genes.

Y. Huang, B. Winston, P. M. Krein, 1999, Clinical and investigative medicine. Medecine clinique et experimentale.

Renin-Angiotensin System Pathway Therapeutics Associated With Improved Outcomes in Males Hospitalized With COVID-19*

Arthur S Slutsky, S. Murthy, D. Maslove, 2022, Critical care medicine.

Therapeutic hypothermia attenuates physiologic, histologic, and metabolomic markers of injury in a porcine model of acute respiratory distress syndrome

A. Sheel, M. Sekhon, D. Griesdale, 2022, Physiological reports.

Divergence in macrophage insulin-like growth factor-I (IGF-I) synthesis induced by TNF-alpha and prostaglandin E2.

D. Riches, S. Young, P. Henson, 1995, Journal of immunology.

Interfaces for noninvasive ventilation: does it matter?

S. Keenan, B. Winston, 2009, Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia.

Early increases in anti-SARS-CoV-2 antibody isotypes associated with organ dysfunction and mortality in patients hospitalized with COVID-19

M. DeMarco, D. Maslove, F. Lamontagne, 2022, Intensive Care Medicine.

Activation of p42mapk/erk2 following engagement of tumor necrosis factor receptor CD120a (p55) in mouse macrophages.

D. Riches, B. Winston, 1995, Journal of immunology.

Complement factor B gene regulation: synergistic effects of TNF-alpha and IFN-gamma in macrophages.

B. Winston, D. Muruve, P. M. Krein, 2002, Journal of immunology.

Metabolomics as a Driver in Advancing Precision Medicine in Sepsis

Michael A Puskarich, Alan E Jones, Kathleen A Stringer, 2017, Pharmacotherapy.

Evaluation of the Role of Mitogen-Activated Protein Kinases in the Expression of Inducible Nitric Oxide Synthase by IFN-γ and TNF-α in Mouse Macrophages

S. Uh, E. Chan, M. Wynes, 1999, The Journal of Immunology.

A B1a–natural IgG–neutrophil axis is impaired in viral- and steroid-associated aspergillosis

B. McDonald, J. Biernaskie, D. Mahoney, 2022, Science Translational Medicine.

TNF-alpha-induced regulation and signalling in macrophages.

E. Chan, D. Riches, B. Winston, 1996, Immunobiology.

Characterization of hPRP4 kinase activation: potential role in signaling.

Y. Huang, T. Deng, B. Winston, 2000, Biochemical and biophysical research communications.

TNF-α-induced Regulation and Signalling in Macrophages

E. Chan, D. Riches, B. Winston, 1996 .

Development of metabolic and inflammatory mediator biomarker phenotyping for early diagnosis and triage of pediatric sepsis

H. Vogel, G. Thompson, A. Joffe, 2015, Critical Care.

Targeting inflammatory monocytes in sepsis-associated encephalopathy and long-term cognitive impairment.

R. Sutherland, C. Doig, P. Kubes, 2018, JCI insight.

Cell therapy with intravascular administration of mesenchymal stromal cells continues to appear safe: An updated systematic review and meta-analysis

J. Marshall, M. Lalu, D. Stewart, 2020, EClinicalMedicine.

Effects of Mesenchymal Stem Cell Treatment on Systemic Cytokine Levels in a Phase 1 Dose Escalation Safety Trial of Septic Shock Patients*

J. Marshall, D. Stewart, J. Granton, 2019, Critical care medicine.

Cellular Immunotherapy for Septic Shock. A Phase I Clinical Trial

J. Marshall, D. Stewart, J. Granton, 2017, American journal of respiratory and critical care medicine.

Longitudinal Plasma Proteomics Analysis Reveals Novel Candidate Biomarkers in Acute COVID-19

D. Goodlett, S. Murthy, F. Lamontagne, 2022, Journal of proteome research.

Cooperative Signaling by Tumor Necrosis Factor Receptors CD120a (p55) and CD120b (p75) in the Expression of Nitric Oxide and Inducible Nitric Oxide Synthase by Mouse Macrophages*

E. Chan, D. Riches, B. Winston, 1998, The Journal of Biological Chemistry.

A1 Adenosine Receptor Upregulation and Activation Attenuates Neuroinflammation and Demyelination in a Model of Multiple Sclerosis

C. Power, V. Yong, J. Schnermann, 2004, The Journal of Neuroscience.

Metabolomics and Biomarker Discovery in Traumatic Brain Injury.

B. Winston, S. Metwaly, M. Banoei, 2018, Journal of neurotrauma.

Plasma metabolomic profile in fibrosing pulmonary sarcoidosis.

R. Machado, R. Baughman, M. Mirsaeidi, 2016, Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG.

Biomarker Phenotype for Early Diagnosis and Triage of Sepsis to the Pediatric Intensive Care Unit

H. Vogel, G. Thompson, A. Joffe, 2018, Scientific Reports.

Evaluation of the role of mitogen-activated protein kinases in the expression of inducible nitric oxide synthase by IFN-gamma and TNF-alpha in mouse macrophages.

S. Uh, E. Chan, M. Wynes, 1999, Journal of immunology.

Angiotensin Receptor Blockers and Angiotensin-Converting Enzyme Inhibitors in COVID-19: Meta-analysis/Meta-regression Adjusted for Confounding Factors

A. Levin, S. Murthy, F. Lamontagne, 2021, CJC Open.

Acute Kidney Injury and Renal Replacement Therapy in COVID-19 Versus Other Respiratory Viruses: A Systematic Review and Meta-Analysis

S. Murthy, F. Lamontagne, D. Vinh, 2021, Canadian journal of kidney health and disease.

Neurobiology of Disease A1 Adenosine Receptor Upregulation and Activation Attenuates Neuroinflammation and Demyelination in a Model of Multiple Sclerosis

C. Power, V. Yong, J. Schnermann, 2004 .

Preferential Involvement of MEK1 in the Tumor Necrosis Factor-α-induced Activation of p42mapk/erk2 in Mouse Macrophages (*)

D. Riches, B. Winston, L. Remigio, 1995, The Journal of Biological Chemistry.

ARDS Metabolic Fingerprints: Characterization, Benchmarking and Potential Mechanistic Interpretation.

O. Fiehn, H. Vogel, B. Winston, 2021, American journal of physiology. Lung cellular and molecular physiology.

Tumor necrosis factor alpha rapidly activates the mitogen-activated protein kinase (MAPK) cascade in a MAPK kinase kinase-dependent, c-Raf-1-independent fashion in mouse macrophages.

D. Riches, G. Johnson, C. Lange-Carter, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Complement Factor B Gene Regulation: Synergistic Effects of TNF-α and IFN-γ in Macrophages1

B. Winston, D. Muruve, Yong Huang, 2002, The Journal of Immunology.

Characterization of IFN‐γ regulation of the complement factor B gene in macrophages

B. Winston, Yong Huang, P. Krein, 2001 .

CHARACTERIZATION OF S. PNEUMONIAE PNEUMONIA-INDUCED MULTIPLE ORGAN DYSFUNCTION SYNDROME: AN EXPERIMENTAL MOUSE MODEL OF GRAM-POSITIVE SEPSIS

B. Winston, D. McCafferty, G. Andonegui, 2009, Shock.

Sex-based analysis of treatment responses in animal models of sepsis: a preclinical systematic review protocol

M. Lalu, B. McDonald, M. Avey, 2023, Systematic Reviews.

National Preclinical Sepsis Platform: developing a framework for accelerating innovation in Canadian sepsis research

C. Ellis, J. Marshall, M. Lalu, 2021, Intensive Care Medicine Experimental.

Growth factor regulation and manipulation in wound repair: to scar or not to scar, that is the question

B. Winston, Yong Huang, P. Krein, 2001 .

Plasma metabolomics for the diagnosis and prognosis of H1N1 influenza pneumonia

H. Vogel, D. Angus, Anand Kumar, 2017, Critical Care.

Integration of metabolic and inflammatory mediator profiles as a potential prognostic approach for septic shock in the intensive care unit

Paul Kubes, H. Vogel, C. Doig, 2015, Critical Care.

Mechanisms of human complement factor B induction in sepsis and inhibition by activated protein C.

D. Zygun, T. Lim, D. Mok, 2009, American journal of physiology. Cell physiology.

Metabolic Profiling of Serum Samples by 1H Nuclear Magnetic Resonance Spectroscopy as a Potential Diagnostic Approach for Septic Shock*

H. Vogel, C. Doig, P. Kubes, 2014, Critical care medicine.

Metabolomics as a novel approach for early diagnosis of pediatric septic shock and its mortality.

H. Vogel, H. Wong, B. Winston, 2013, American journal of respiratory and critical care medicine.

Cytokine Responses in Severe Traumatic Brain Injury: Where There Is Smoke, Is There Fire?

P. Couillard, B. Winston, M. Banoei, 2019, Neurocritical Care.

Metabolomic and metallomic profile differences between Veterans and Civilians with Pulmonary Sarcoidosis

H. Vogel, M. Campos, M. Mirsaeidi, 2019, Scientific Reports.

Using metabolomics to predict severe traumatic brain injury outcome (GOSE) at 3 and 12 months

D. Wishart, L. Hazrati, K. Barlow, 2023, Critical Care.

Early diagnosis and triage of pediatric sepsis using metabolic and inflammatory mediator biomarkers

H. Vogel, G. Thompson, A. Joffe, 2015 .

Sepsis without SIRS is still sepsis.

B. Winston, B. Yipp, 2015, Annals of translational medicine.

Enhanced production of IGF‐I in the lungs of fibroproliferative ARDS patients

C. Doig, F. Green, B. Winston, 2014, Physiological reports.

Mortality Risk Profiles for Sepsis: A Novel Longitudinal and Multivariable Approach

D. Cook, D. Dwivedi, F. Lellouche, 2019, Critical care explorations.

Sequential expression of IGF-IB followed by active TGF-β1 induces synergistic pulmonary fibroproliferation in vivo.

B. Winston, M. Kelly, G. Andonegui, 2012, American journal of physiology. Lung cellular and molecular physiology.

Studies on the structure-function relationships of Neurospora crassa pyruvate kinase: refolding and reactivation following denaturation in guanidine hydrochloride.

B. Winston, M. Kapoor, D. Quon, 1981, The International journal of biochemistry.