J. Silvius

发表

Acyl-CoA binding proteins inhibit the nonenzymic S-acylation of cysteinyl-containing peptide sequences by long-chain acyl-CoAs.

R. Leventis, G. Juel, J. Knudsen, 1997, Biochemistry.

Novel thioester reagents afford efficient and specific S-acylation of unprotected peptides under mild conditions in aqueous solution.

J. Silvius, S. L. W. Sang, 2005, The journal of peptide research : official journal of the American Peptide Society.

Lipidated peptides as tools for understanding the membrane interactions of lipid-modified proteins

J. Silvius, 2002 .

Differential effects of acyl-CoA binding protein on enzymatic and non-enzymatic thioacylation of protein and peptide substrates.

R. Leventis, J. Knudsen, J. Silvius, 2000, Biochimica et biophysica acta.

Lipid Modifications of Intracellular Signal-Transducing Proteins

J. Silvius, 1999 .

Fluorescence measurement of lipid-binding affinity and interbilayer transfer of bimane-labeled lipidated peptides.

J. Silvius, 1999, Methods in molecular biology.

Mechanisms of Ras Protein Targeting in Mammalian Cells

J. Silvius, 2002, The Journal of Membrane Biology.

Physiological role and membrane lipid modulation of the membrane-bound (Mg2+, na+)-adenosine triphosphatase activity in Acholeplasma laidlawii

J. Silvius, R. McElhaney, D. C. Jinks, 1978, Journal of bacteriology.

Role of cholesterol in lipid raft formation: lessons from lipid model systems.

J. Silvius, John R Silvius, 2003, Biochimica et biophysica acta.

Artificially Lipid-anchored Proteins Can Elicit Clustering-induced Intracellular Signaling Events in Jurkat T-Lymphocytes Independent of Lipid Raft Association*

Tian-yun Wang, R. Leventis, J. Silvius, 2005, Journal of Biological Chemistry.

Membrane Phosphatidylserine Regulates Surface Charge and Protein Localization

Tony Yeung, Sergio Grinstein, S. Grinstein, 2008, Science.

Penetratin and related cell-penetrating cationic peptides can translocate across lipid bilayers in the presence of a transbilayer potential.

L. Roudaia, J. Silvius, S. L. W. Sang, 2003, Biochemistry.

HeLa Cell Entry by Guanidinium‐Rich β‐Peptides: Importance of Specific Cation–Cell Surface Interactions

S. Gellman, A. Menon, Terra B. Potocky, 2007, Chembiochem : a European journal of chemical biology.

Calcium-induced lateral phase separations in phosphatidylcholine-phosphatidic acid mixtures. A Raman spectroscopic study.

J. Silvius, M. Pézolet, R. Kouaouci, 1985, Biochemistry.

Novel fluorescent phospholipids for assays of lipid mixing between membranes.

R. Leventis, J. Silvius, M. Zuckermann, 1987, Biochemistry.

A novel strategy affords high-yield coupling of antibody Fab' fragments to liposomes.

J. Silvius, S. Shahinian, 1995, Biochimica et biophysica acta.

Doubly-lipid-modified protein sequence motifs exhibit long-lived anchorage to lipid bilayer membranes.

J. Silvius, S. Shahinian, Serge Shahinian, 1995, Biochemistry.

Cholesterol does not induce segregation of liquid-ordered domains in bilayers modeling the inner leaflet of the plasma membrane.

Tian-yun Wang, J. Silvius, T. Wang, 2001, Biophysical journal.

Molecular organization and stability of hydrated dispersions of headgroup-modified phosphatidylethanolamine analogues.

P. Yeagle, R. Rand, R. Leventis, 1991, Biochemistry.

Multiple cellular proteins modulate the dynamics of K-ras association with the plasma membrane.

R. Rich, Chen-ju Lin, R. Leventis, 2010, Biophysical journal.

Stability and fusion of lipid vesicles containing headgroup-modified analogues of phosphatidylethanolamine.

J. Silvius, P. M. Brown, 1989, Biochimica et biophysica acta.

‘Slow Artifacts’ in Assays of Lipid Mixing between Membranes

R. Leventis, J. Silvius, P. M. Brown, 1988 .

Effects of cholesterol on the divalent cation-mediated interactions of vesicles containing amino and choline phospholipids.

J. Silvius, L. Stamatotos, 1987, Biochimica et biophysica acta.

Divalent cation induced fusion and lipid lateral segregation in phosphatidylcholine-phosphatidic acid vesicles.

R. Rand, R. Leventis, J. Silvius, 1986, Biochemistry.

Interactions of mammalian cells with lipid dispersions containing novel metabolizable cationic amphiphiles.

R. Leventis, J. Silvius, 1990, Biochimica et biophysica acta.

Interbilayer transfer of phospholipid-anchored macromolecules via monomer diffusion.

J. Silvius, M. Zuckermann, 1993, Biochemistry.

Anomalous mixing of zwitterionic and anionic phospholipids with double-chain cationic amphiphiles in lipid bilayers.

J. Silvius, 1991, Biochimica et biophysica acta.

Insertion of an uncharged polypeptide into the mitochondrial inner membrane does not require a trans-bilayer electrochemical potential: effects of positive charges.

H. McBride, G. Shore, J. Silvius, 1995, Biochimica et biophysica acta.

Direct Membrane Insertion of Voltage-dependent Anion-selective Channel Protein Catalyzed by Mitochondrial Tom20

E. Schleiff, G. Shore, J. Silvius, 1999, The Journal of cell biology.

Why do Prokaryotes Regulate Membrane Fluidity

J. Silvius, R. McElhaney, N. Mak, 1980 .

Lipid microdomains in model and biological membranes: how strong are the connections?

J. Silvius, 2005, Quarterly Reviews of Biophysics.

Use of cyclodextrins to monitor transbilayer movement and differential lipid affinities of cholesterol.

R. Leventis, J. Silvius, 2001, Biophysical journal.

Different sphingolipids show differential partitioning into sphingolipid/cholesterol-rich domains in lipid bilayers.

Tian-yun Wang, J. Silvius, T. Wang, 2000, Biophysical journal.

Fluorescence-based evaluation of the partitioning of lipids and lipidated peptides into liquid-ordered lipid microdomains: a model for molecular partitioning into "lipid rafts".

Tian-yun Wang, R. Leventis, J. Silvius, 2000, Biophysical journal.

Lipid-modified, cysteinyl-containing peptides of diverse structures are efficiently S-acylated at the plasma membrane of mammalian cells

R. Leventis, J. Silvius, H. Schroeder, 1996, The Journal of cell biology.

S-Acylation and plasma membrane targeting of the farnesylated carboxyl-terminal peptide of N-ras in mammalian fibroblasts.

H. Waldmann, R. Leventis, J. Silvius, 1997, Biochemistry.

Membrane Bending Tug of War

J. Silvius, 2012, Science.

Partitioning of membrane molecules between raft and non-raft domains: insights from model-membrane studies.

J. Silvius, 2005, Biochimica et biophysica acta.

Sphingolipid partitioning into ordered domains in cholesterol-free and cholesterol-containing lipid bilayers.

Tian-yun Wang, J. Silvius, 2003, Biophysical journal.

CHEMOENZYMATIC SYNTHESIS OF FLUORESCENT N-RAS LIPOPEPTIDES AND THEIR USE IN MEMBRANE LOCALIZATION STUDIES IN VIVO

A. Wittinghofer, H. Waldmann, J. Kuhlmann, 1997 .

Cysteine-containing peptide sequences exhibit facile uncatalyzed transacylation and acyl-CoA-dependent acylation at the lipid bilayer interface.

J. Silvius, S. Quesnel, Susan Quesnel, 1994, Biochemistry.

Partitioning of lipidated peptide sequences into liquid-ordered lipid domains in model and biological membranes.

R. Leventis, J. Silvius, T. Wang, 2001, Biochemistry.

Cholesterol at different bilayer concentrations can promote or antagonize lateral segregation of phospholipids of differing acyl chain length.

M. Lafleur, J. Silvius, D. del Giudice, 1996, Biochemistry.

Structure and Nomenclature

J. Silvius, 1994 .

Membranes: first steps to rafts?

J. Silvius, 2012, Nature chemical biology.

Lipid phase behavior and calcium-induced fusion of phosphatidylethanolamine-phosphatidylserine vesicles. Calorimetric and fusion studies

J. Silvius, J. Gagné, 1984 .

Physical properties and surface interactions of bilayer membranes containing N-methylated phosphatidylethanolamines.

T. Diacovo, S. Hui, P. Yeagle, 1985, Biochemistry.

Calcium-induced fusion and lateral phase separations in phosphatidylcholine-phosphatidylserine vesicles. Correlation by calorimetric and fusion measurements

J. Silvius, J. Gagné, 1984 .

Solid- and liquid-phase equilibria in phosphatidylcholine/phosphatidylethanolamine mixtures. A calorimetric study.

J. Silvius, 1986, Biochimica et biophysica acta.

Lipid and protein composition and thermotropic lipid phase transitions in fatty acid-homogeneous membranes of Acholeplasma laidlawii B.

J. Silvius, R. McElhaney, N. Mak, 1980, Biochimica et biophysica acta.

Import of precursor proteins into mitochondria: site of polypeptide unfolding.

G. Shore, S. Randall, J. Silvius, 1990, The Journal of biological chemistry.

Lipid-binding characteristics of the polybasic carboxy-terminal sequence of K-ras4B.

R. Leventis, J. Silvius, 1998, Biochemistry.

Spontaneous interbilayer transfer of phospholipids: dependence on acyl chain composition.

R. Leventis, J. Silvius, 1993, Biochemistry.

Membrane enzymes: artifacts in Arrhenius plots due to temperature dependence of substrate-binding affinity.

J. Silvius, R. McElhaney, B. D. Read, 1978, Science.

Membrane lipid biosynthesis in Acholeplasma laidlawii B. Investigations into the in vivo regulation of the quantity and hydrocarbon chain lengths of de novo biosynthesized fatty aicds in response to exogenously supplied fatty acids.

J. Silvius, R. McElhaney, Y. Saito, 1977, Archives of biochemistry and biophysics.

Membrane lipid biosynthesis in Acholeplasma laidlawii B. Relationship between fatty acid structure and the positional distribution of esterified fatty acids in phospho- and glycolipids from growing cells.

J. Silvius, R. McElhaney, Y. Saito, 1977, Archives of biochemistry and biophysics.

High-yield coupling of antibody Fab' fragments to liposomes containing maleimide-functionalized lipids.

J. Silvius, S. Shahinian, 2004, Methods in enzymology.

Mechanisms of delivery of liposome-encapsulated cytosine arabinoside to CV-1 cells in vitro. Fluorescence-microscopic and cytotoxicity studies.

J. Silvius, P. M. Brown, 1990, Biochimica et biophysica acta.

pH-dependent stability and fusion of liposomes combining protonatable double-chain amphiphiles with phosphatidylethanolamine.

T. Diacovo, R. Leventis, J. Silvius, 1987, Biochemistry.

Assessment of the Roles of Ordered Lipid Microdomains in Post‐Endocytic Trafficking of Glycosyl‐Phosphatidylinositol‐Anchored Proteins in Mammalian Fibroblasts

Mohammad Refaei, R. Leventis, J. Silvius, 2011, Traffic.

Partitioning of exchangeable fluorescent phospholipids and sphingolipids between different lipid bilayer environments.

J. Silvius, M. Gardam, J. Itovitch, 1989, Biochemistry.

Obatoclax is a direct and potent antagonist of membrane-restricted Mcl-1 and is synthetic lethal with treatment that induces Bim

Jerry Pelletier, R. Cencic, J. Pelletier, 2015, BMC Cancer.

Calcium-induced lipid phase separations and interactions of phosphatidylcholine/anionic phospholipid vesicles. Fluorescence studies using carbazole-labeled and brominated phospholipids.

J. Silvius, 1990, Biochemistry.

Intermembrane lipid-mixing assays using acyl chain-labeled coumarinyl phospholipids.

R. Leventis, J. Silvius, 1993, Methods in enzymology.

Mutational and biochemical analysis of plasma membrane targeting mediated by the farnesylated, polybasic carboxy terminus of K-ras4B.

R. Leventis, J. Silvius, M. Roy, 2000, Biochemistry.

Fluorescence-quenching and resonance energy transfer studies of lipid microdomains in model and biological membranes (Review)

I. Nabi, J. Silvius, 2006, Molecular membrane biology.

Fluorescence energy transfer reveals microdomain formation at physiological temperatures in lipid mixtures modeling the outer leaflet of the plasma membrane.

J. Silvius, John R Silvius, 2003, Biophysical journal.

Effects of phospholipid acyl chain structure on physical properties: I. Isobranched phosphatidylcholines

J. Silvius, R. McElhaney, 1979 .

Steric and not structure-specific factors dictate the endocytic mechanism of glycosylphosphatidylinositol-anchored proteins

Mohammad Refaei, R. Leventis, J. Silvius, 2009, The Journal of cell biology.

Solubilization and functional reconstitution of biomembrane components.

J. Silvius, 1992, Annual review of biophysics and biomolecular structure.

Competition between cholesterol and phosphatidylcholine for the hydrophobic surface of sarcoplasmic reticulum Ca2+-ATPase.

J. Silvius, O. H. Griffith, P. Jost, 1984, Biochemistry.

Lipid--protein multiple binding equilibria in membranes.

J. Silvius, O. H. Griffith, L. Hokin, 1981, Biochemistry.

Thermotropic properties of phospholipid analogues.

J. Silvius, 1991, Chemistry and physics of lipids.

Role of head group structure in the phase behavior of amino phospholipids. 2. Lamellar and nonlamellar phases of unsaturated phosphatidylethanolamine analogues.

S. Hui, P. Yeagle, J. Silvius, 1986, Biochemistry.

Kinetics and thermodynamics of calcium-induced lateral phase separations in phosphatidic acid containing bilayers.

J. Silvius, J. Gagné, I. Graham, 1985, Biochemistry.

Interactions of cationic lipid vesicles with negatively charged phospholipid vesicles and biological membranes.

R. Leventis, J. Silvius, M. Zuckermann, 1988, Biochemistry.

Lipid compositional manipulation in Acholeplasma laidlawii B. Effect of exogenous fatty acids on fatty acid composition and cell growth when endogenous fatty acid production is inhibited.

J. Silvius, R. McElhaney, 1978, Canadian journal of biochemistry.

Membrane lipid physical state and modulation of the Na+,Mg2+-ATPase activity in Acholeplasma laidlawii B.

J. Silvius, R. McElhaney, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Membrane Lipid Biosynthesis in Acholeplasma laidlawii B: Elongation of Medium- and Long-Chain Exogenous Fatty Acids in Growing Cells

J. Silvius, R. McElhaney, Y. Saito, 1978, Journal of bacteriology.

Role of head group structure in the phase behavior of amino phospholipids. 1. Hydrated and dehydrated lamellar phases of saturated phosphatidylethanolamine analogues.

T. O'Leary, J. Silvius, P. M. Brown, 1986, Biochemistry.

Molecular properties of membrane lipids and activity of a membrane adenosine triphosphatase from Acholeplasma laidlawii B.

J. Silvius, R. McElhaney, 1982, Reviews of infectious diseases.

Partitioning of fluorescent phospholipid probes between different bilayer environments. Estimation of the free energy of interlipid hydrogen bonding.

R. Leventis, J. Silvius, T. Shin, 1991, Biochemistry.

Thermotropic properties of bilayers containing branched-chain phospholipids. Calorimetric, Raman, and 31P NMR studies.

Michael J. Lyons, P. Yeagle, T. O'Leary, 1985, Biochemistry.

Thermotropic phase transitions of phosphatidylcholines with odd-numbered n-acyl chains.

J. Silvius, R. McElhaney, B. D. Read, 1979, Biochimica et biophysica acta.

Rat kidney Na-K pumps incorporated into low-K+ sheep red blood cell membranes are stimulated by anti-Lp antibody.

P. Dunham, J. Silvius, R. Blostein, 1992, The American journal of physiology.

Receptor Activation Alters Inner Surface Potential During Phagocytosis

Mark Philips, Tony Yeung, Sergio Grinstein, 2006, Science.

Intermixing of dipalmitoylphosphatidylcholine with phospho- and sphingolipids bearing highly asymmetric hydrocarbon chains.

J. Silvius, M. Gardam, 1989, Biochimica et biophysica acta.

Effects of phospholipid acyl chain structure on thermotropic phase properties. 3. Phosphatidylcholines with (−), and (±)-anteiso acyl chains

J. Silvius, R. McElhaney, 1980 .

Effects of phospholipid acylchain structure on thermotropic phase properties. 2: Phosphatidylcholines with unsaturated or cyclopropane acyl chains

J. Silvius, R. McElhaney, 1979 .

The interaction of a synthetic mitochondrial signal peptide with lipid membranes is independent of transbilayer potential.

G. Shore, J. Silvius, I. Skerjanc, 1987, The EMBO journal.

Experimental and Monte Carlo simulation studies of the thermodynamics of polyethyleneglycol chains grafted to lipid bilayers.

M. Lafleur, J. Silvius, M. Zuckermann, 1998, Biophysical journal.

Effect of alkali cations on freeze-thaw-dependent reconstitution of amino acid transport from Ehrlich ascites cell plasma membrane.

J. Silvius, R. Johnstone, J. Mccormick, 1985, The Journal of biological chemistry.

K-ras4B and prenylated proteins lacking "second signals" associate dynamically with cellular membranes.

R. Leventis, J. Silvius, Donato Terrone, 2005, Molecular biology of the cell.

Fluorimetric evaluation of the affinities of isoprenylated peptides for lipid bilayers.

F. L'Heureux, J. Silvius, François L'heureux, 1994, Biochemistry.

A Novel "Prebinding" Strategy Dramatically Enhances Sortase-Mediated Coupling of Proteins to Liposomes.

R. Leventis, J. Silvius, 2017, Bioconjugate chemistry.

The presence of PEG-lipids in liposomes does not reduce melittin binding but decreases melittin-induced leakage.

M. Lafleur, J. Silvius, J. Bian, 2002, Biochimica et biophysica acta.

G-protein signaling leverages subunit-dependent membrane affinity to differentially control βγ translocation to intracellular membranes

N. Gautam, W. Karunarathne, J. Silvius, 2012, Proceedings of the National Academy of Sciences.

Role of specific acidic lipids on the reconstitution of Na(+)-dependent amino acid transport in proteoliposomes derived from Ehrlich cell plasma membranes.

J. Silvius, S. Dhe-Paganon, R. Johnstone, 1990, Biochemistry.

Proving Lipid Rafts Exist: Membrane Domains in the Prokaryote Borrelia burgdorferi Have the Same Properties as Eukaryotic Lipid Rafts

S. Chiantia, E. London, J. Benach, 2013, PLoS pathogens.

Cholesterol modulation of lipid intermixing in phospholipid and glycosphingolipid mixtures. Evaluation using fluorescent lipid probes and brominated lipid quenchers.

J. Silvius, J R Silvius, 1992, Biochemistry.

Membrane Lipid Fluidity and Physical State and the Activity of the Na, Mg-ATPase of Acholeplasma Laidlawii B.

J. Silvius, R. McElhaney, 1982, Biophysical journal.

Quantitative experimental assessment of macromolecular crowding effects at membrane surfaces.

R. Leventis, J. Silvius, 2010, Biophysical journal.

Identification of hydrophobic residues in the signal sequence of mitochondrial preornithine carbamyltransferase that enhance the rate of precursor import.

G. Shore, J. Silvius, I. Skerjanc, 1988, Journal of Biological Chemistry.

Growth and membrane lipid properties of Acholeplasma laidlawii B lacking fatty acid heterogeneity

J. Silvius, R. McElhaney, 1978, Nature.

Resonance energy transfer imaging of phospholipid vesicle interaction with a planar phospholipid membrane: undulations and attachment sites in the region of calcium-mediated membrane--membrane adhesion

F. S. Cohen, W. Niles, J. Silvius, 1996, The Journal of general physiology.

Non-linear Arrhenius plots and the analysis of reaction and motional rates in biological membranes.

J. Silvius, R. McElhaney, 1981, Journal of theoretical biology.

Delivery of ion pumps from exogenous membrane-rich sources into mammalian red blood cells.

J. Silvius, R. Blostein, J. Munzer, 1992, Journal of Biological Chemistry.

Incorporation of Artificial Lipid-Anchored Proteins into Cultured Mammalian Cells.

R. Leventis, J. Silvius, 2017, Methods in molecular biology.

Characterization of the resonance energy transfer couple coumarin-BODIPY and its possible applications in protein-lipid research.

B. de Kruijff, R. Keller, J. Silvius, 1995, Biochemical and biophysical research communications.

Membrane Phosphatidylserine Regulates Surface Charge and Protein Localization

S. Grinstein, J. Silvius, T. Yeung, 2008, Science.

Characterization of the novel resonance energy transfer couple coumarin-BODIPY and its possible applications

B. Kruijff, R. Keller, J. Silvius, 1995 .

An amphiphilic lipid-binding domain influences the topology of a signal-anchor sequence in the mitochondrial outer membrane.

G. Shore, J. Silvius, N. Steenaart, 1996, Biochemistry.