C. Scott

发表

F420-dependent enzymes - potential for applications in biotechnology.

G. Grogan, Matthew C. Taylor, C. Scott, 2013, Trends in biotechnology.

How many genetic options for evolving insecticide resistance in heliothine and spodopteran pests?

J. Oakeshott, R. Russell, C. Scott, 2013, Pest management science.

Heterologous Expression and Biochemical Characterisation of Fourteen Esterases from Helicoverpa armigera

J. Oakeshott, A. Devonshire, R. Russell, 2013, PloS one.

Organophosphate and Pyrethroid Hydrolase Activities of Mutant Esterases from the Cotton Bollworm Helicoverpa armigera

J. Oakeshott, R. Russell, Jian-wei Liu, 2013, PloS one.

Gene identification and proteomic analysis of the esterases of the cotton bollworm, Helicoverpa armigera.

J. Oakeshott, P. M. Campbell, R. Russell, 2010, Insect biochemistry and molecular biology.

The evolution of new enzyme function: lessons from xenobiotic metabolizing bacteria versus insecticide-resistant insects

J. Oakeshott, R. Russell, C. Jackson, 2011, Evolutionary applications.

The evolving story of AtzT, a periplasmic binding protein

J. Newman, T. Peat, T. Nebl, 2019, Acta crystallographica. Section D, Structural biology.

Cofactor promiscuity among F 420 -dependent reductases enables them to catalyse both oxidation and reduction of the same substrate

Susan E. Brown, J. Oakeshott, R. Russell, 2012 .

An unexpected vestigial protein complex reveals the evolutionary origins of an s-triazine catabolic enzyme

J. Newman, T. Peat, Jian-wei Liu, 2018, The Journal of Biological Chemistry.

A novel decarboxylating amidohydrolase involved in avoiding metabolic dead ends during cyanuric acid catabolism in Pseudomonas sp. strain ADP

J. Newman, T. Peat, C. Scott, 2018, PloS one.

Crystal structure of a putrescine aminotransferase from Pseudomonas sp. strain AAC.

J. Newman, T. Peat, C. Scott, 2017, Acta crystallographica. Section F, Structural biology communications.

X-ray crystal structure of a malonate-semialdehyde dehydrogenase from Pseudomonas sp. strain AAC.

J. Newman, T. Peat, C. Scott, 2017, Acta crystallographica. Section F, Structural biology communications.

Computer-Guided Surface Engineering for Enzyme Improvement

A. Warden, C. Scott, M. Wilding, 2018, Scientific Reports.

Bacterial degradation of strobilurin fungicides: a role for a promiscuous methyl esterase activity of the subtilisin proteases?

J. Oakeshott, R. Russell, A. Warden, 2011 .

Evolutionary Expansion of the Amidohydrolase Superfamily in Bacteria in Response to the Synthetic Compounds Molinate and Diuron

J. Oakeshott, C. Jackson, P. Carr, 2015, Applied and Environmental Microbiology.

Evolution of atrazine-degrading capabilities in the environment

F. Martin-Laurent, C. Scott, N. Udikovic-Kolic, 2012, Applied Microbiology and Biotechnology.

Sugar analog synthesis by in vitro biocatalytic cascade: A comparison of alternative enzyme complements for dihydroxyacetone phosphate production as a precursor to rare chiral sugar synthesis

N. Turner, Matthew C. Taylor, C. Scott, 2017, PloS one.

Catalytic Improvement and Evolution of Atrazine Chlorohydrolase (cid:1)

J. Oakeshott, T. Sutherland, R. Russell, 2009 .

An unexpected vestigial protein complex reveals the evolutionary origins of an s-triazine catabolic enzyme

J. Newman, T. Peat, Jian-wei Liu, 2018, The Journal of Biological Chemistry.

Structural and biochemical characterization of the biuret hydrolase (BiuH) from the cyanuric acid catabolism pathway of Rhizobium leguminasorum bv. viciae 3841

J. Newman, T. Peat, C. Scott, 2018, PloS one.

A (cid:2) -Alanine Catabolism Pathway Containing a Highly Promiscuous (cid:3) -Transaminase in the 12-Aminododecanate-Degrading Pseudomonas sp. Strain AAC

J. Newman, T. Peat, C. Scott, 2016 .

Characterization of the Lactococcus lactis transcription factor FlpA and demonstration of an in vitro switch

Jeffrey Green, J. Guest, C. Scott, 2000, Molecular microbiology.

DNA target sequence and FNR‐dependent gene expression

Jeffrey Green, C. Scott, Jonathan D. Partridge, 2003, FEBS letters.

One-Pot Multienzymatic Transformation of NH3, CO2, and Ornithine into the Organic Nitrogen Plant Fertilizer Citrulline Using a Single Recombinant Lysate of E. coli

Hye-Kyung Kim, G. Estavillo, C. Scott, 2019, ACS Sustainable Chemistry & Engineering.

Intramolecular Epistasis and the Evolution of a New Enzymatic Function

J. Oakeshott, R. Russell, L. Jermiin, 2012, PloS one.

Hyperthermophilic Carbamate Kinase Stability and Anabolic In Vitro Activity at Alkaline pH

J. Oakeshott, Hye-Kyung Kim, M. Latter, 2017, Applied and Environmental Microbiology.

Asymmetric ene-reduction of α,β-unsaturated compounds by F420-dependent oxidoreductases A (FDOR-A) enzymes from Mycobacterium smegmatis

C. Jackson, R. Speight, C. Scott, 2022, bioRxiv.

Synthetic Biology Approaches to Hydrocarbon Biosensors: A Review

C. Scott, N. Coleman, Claudia F. Moratti, 2022, Frontiers in Bioengineering and Biotechnology.

Characterization of the Escherichia coli K-12 ydhYVWXUT operon: regulation by FNR, NarL and NarP.

R. Poole, Jeffrey Green, D. Browning, 2008, Microbiology.

Physiology, Biochemistry, and Applications of F420- and Fo-Dependent Redox Reactions

J. Oakeshott, C. Jackson, A. Warden, 2016, Microbiology and Molecular Reviews.

Detoxification of G- and V-series nerve agents by the phosphotriesterase OpdA

C. Scott, F. Worek, T. Wille, 2012 .

Characterisation of Hybrid Polymersome Vesicles Containing the Efflux Pumps NaAtm1 or P-Glycoprotein

M. Rug, R. Callaghan, P. Beales, 2020, Polymers.

Ongoing functional evolution of the bacterial atrazine chlorohydrolase AtzA

J. Oakeshott, F. Martin-Laurent, C. Scott, 2014, Biodegradation.

The Evolution of New Catalytic Mechanisms for Xenobiotic Hydrolysis in Bacterial Metalloenzymes

C. Jackson, C. Scott, C. Hartley, 2016 .

Characterization of the phenylurea hydrolases A and B: founding members of a novel amidohydrolase subgroup.

J. Oakeshott, I. Horne, R. Russell, 2009, The Biochemical journal.

Evolution of atrazine-degrading capabilities in the environment

F. Martin-Laurent, C. Scott, N. Udikovic-Kolic, 2012, Applied Microbiology and Biotechnology.

A 5000-Fold Increase in the Specificity of a Bacterial Phosphotriesterase for Malathion through Combinatorial Active Site Mutagenesis

C. Jackson, P. Carr, A. Warden, 2014, PloS one.

Structure-Based Rational Design of a Phosphotriesterase

J. Oakeshott, T. Sutherland, I. Horne, 2009, Applied and Environmental Microbiology.

High-Resolution X-Ray Structures of Two Functionally Distinct Members of the Cyclic Amide Hydrolase Family of Toblerone Fold Enzymes

J. Newman, T. Peat, C. Scott, 2017, Applied and Environmental Microbiology.

X-Ray Structure and Mutagenesis Studies of the N-Isopropylammelide Isopropylaminohydrolase, AtzC

J. Newman, T. Peat, A. Warden, 2015, PloS one.

The structure of the hexameric atrazine chlorohydrolase AtzA

J. Newman, T. Peat, A. Warden, 2015, Acta crystallographica. Section D, Biological crystallography.

X-Ray Structure of the Amidase Domain of AtzF, the Allophanate Hydrolase from the Cyanuric Acid-Mineralizing Multienzyme Complex

P. M. Campbell, J. Newman, T. Peat, 2014, Applied and Environmental Microbiology.

Free-Enzyme Bioremediation of Pesticides: A case study for the enzymatic remediation of organophosphorous insecticide residues

J. Oakeshott, R. Russell, C. Begley, 2011 .

A free-enzyme catalyst for the bioremediation of environmental atrazine contamination.

J. Oakeshott, R. Russell, J. Brodie, 2010, Journal of environmental management.

Catalytic Improvement and Evolution of Atrazine Chlorohydrolase

J. Oakeshott, T. Sutherland, R. Russell, 2009, Applied and Environmental Microbiology.

Proteomic and molecular analyses of esterases associated with monocrotophos resistance in Helicoverpa armigera

J. Oakeshott, P. M. Campbell, R. Russell, 2012 .

F420H2-Dependent Degradation of Aflatoxin and other Furanocoumarins Is Widespread throughout the Actinomycetales

J. Oakeshott, R. Russell, A. Warden, 2012, PloS one.

Improved production of the non-native cofactor F420 in Escherichia coli

C. Jackson, C. Scott, Hadi Nazem-Bokaee, 2021, Scientific Reports.

Cofactor F420-Dependent Enzymes: An Under-Explored Resource for Asymmetric Redox Biocatalysis

C. Jackson, A. Warden, C. Scott, 2019, Catalysts.

A revised biosynthetic pathway for the cofactor F420 in prokaryotes

N. Tokuriki, E. Baker, B. Palmer, 2019, Nature Communications.

Identification and characterization of two families of F420H2-dependent reductases from Mycobacteria that catalyse aflatoxin degradation

J. Oakeshott, P. M. Campbell, R. Russell, 2010, Molecular microbiology.

A revised biosynthetic pathway for the cofactor F420 in bacteria

N. Tokuriki, E. Baker, B. Palmer, 2018, bioRxiv.

Mycobacterial F420H2-Dependent Reductases Promiscuously Reduce Diverse Compounds through a Common Mechanism

J. Oakeshott, R. Russell, C. Jackson, 2017, Front. Microbiol..

Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction

Thomas S. Peat, Janet Newman, Subha Kalyaanamoorthy, 2017 .

A β-Alanine Catabolism Pathway Containing a Highly Promiscuous ω-Transaminase in the 12-Aminododecanate-Degrading Pseudomonas sp. Strain AAC

J. Newman, T. Peat, C. Scott, 2016, Applied and Environmental Microbiology.

Identification of novel transaminases from a 12-aminododecanoic acid-metabolizing Pseudomonas strain

C. Scott, M. Wilding, E. F. Walsh, 2015, Microbial biotechnology.

Cofactor and Process Engineering for Nicotinamide Recycling and Retention in Intensified Biocatalysis

R. Speight, C. Scott, Charlotte C Williams, 2022, Catalysts.

A global response to sulfur starvation in Pseudomonas putida and its relationship to the expression of low-sulfur-content proteins.

J. Oakeshott, T. Sutherland, R. Russell, 2007, FEMS microbiology letters.

Two operons that encode FNR‐like proteins in Lactococcus lactis

C. Shearman, M. Gasson, H. Griffin, 1999, Molecular microbiology.

Adaptive laboratory evolution of native methanol assimilation in Saccharomyces cerevisiae

I. Paulsen, K. Valgepea, M. Plan, 2020, Nature Communications.

An improved and general streamlined phylogenetic protocol applied to the fatty acid desaturase family.

Robert Speight, R. Speight, C. Scott, 2017, Molecular phylogenetics and evolution.

Esterase-based metabolic resistance to insecticides in heliothine and spodopteran pests

J. Oakeshott, R. Russell, M. Teese, 2010 .

NO sensing by FNR: regulation of the Escherichia coli NO‐detoxifying flavohaemoglobin, Hmp

Guanghui Wu, M. N. Hughes, R. Poole, 2002, The EMBO journal.

Constrained evolution of a bispecific enzyme: lessons for biocatalyst design.

C. Jackson, C. Scott, C Scott, 2017, Organic & biomolecular chemistry.

Native and synthetic methanol assimilation in Saccharomyces cerevisiae

I. Paulsen, K. Valgepea, E. Marcellin, 2019, bioRxiv.

The enzymatic basis for pesticide bioremediation

J. Oakeshott, R. Russell, R. Lal, 2008, Indian Journal of Microbiology.

Isomer-specific comparisons of the hydrolysis of synthetic pyrethroids and their fluorogenic analogues by esterases from the cotton bollworm Helicoverpa armigera.

J. Oakeshott, A. Devonshire, R. Russell, 2015, Pesticide biochemistry and physiology.

Engineered Enzymes that Retain and Regenerate their Cofactors Enable Continuous-Flow Biocatalysis

A. Warden, T. Nebl, N. Turner, 2019, bioRxiv.

Active Site Desolvation and Thermostability Trade-Offs in the Evolution of Catalytically Diverse Triazine Hydrolases.

C. Jackson, P. Carr, C. Scott, 2016, Biochemistry.

Active site mutations of F420-dependent alkene reductases reverse stereoselectivity

C. Jackson, R. Speight, C. Scott, 2023, bioRxiv.

Heterologous expression of the methyl carbamate-degrading hydrolase MCD.

J. Oakeshott, P. M. Campbell, R. Russell, 2009, Journal of biotechnology.

Efficacy of an organophosphorus hydrolase enzyme (OpdA) in human serum and minipig models of organophosphorus insecticide poisoning

M. Eddleston, C. Scott, F. Worek, 2019, Clinical toxicology.

OpdA, a bacterial organophosphorus hydrolase, prevents lethality in rats after poisoning with highly toxic organophosphorus pesticides.

J. Oakeshott, T. Sutherland, M. Eddleston, 2008, Toxicology.

Bacterial catabolism of s-triazine herbicides: biochemistry, evolution and application.

J. Newman, T. Peat, C. Jackson, 2020, Advances in microbial physiology.

An in vivo gene amplification system for high level expression in Saccharomyces cerevisiae

Christopher B. Howard, M. Trau, C. Vickers, 2022, Nature Communications.

Immobilization of organophosphohydrolase OpdA from Agrobacterium radiobacter by overproduction at the surface of polyester inclusions inside engineered Escherichia coli

B. Rehm, C. Scott, P. Blatchford, 2012, Biotechnology and bioengineering.

Engineering eukaryote-like regulatory circuits to expand artificial control mechanisms for metabolic engineering in Saccharomyces cerevisiae

Christopher B. Howard, M. Trau, C. Vickers, 2022, Communications Biology.

Corrigendum to “Gene identification and proteomic analysis of the esterases of the cotton bollworm, Helicoverpa armigera” [Insect Biochem. Mol. Biol. 40 (2010) 1–16]

J. Oakeshott, P. M. Campbell, R. Russell, 2010 .

Cyanuric acid hydrolase: evolutionary innovation by structural concatenation

J. Newman, T. Peat, N. Cowieson, 2013, Molecular microbiology.

A member of the cAMP receptor protein family of transcription regulators in Mycobacterium tuberculosis is required for virulence in mice and controls transcription of the rpfA gene coding for a resuscitation promoting factor

Jason Hinds, J. Hinds, Jeffrey Green, 2005, Molecular microbiology.

Pharmacokinetics of OpdA, an organophosphorus hydrolase, in the African green monkey.

D. Ollis, K. Mansfield, C. Jackson, 2010, Biochemical pharmacology.

Escherichia coli Transcriptome Dynamics during the Transition from Anaerobic to Aerobic Conditions*

Yue-qin Tang, R. Poole, Jeffrey Green, 2006, Journal of Biological Chemistry.

Functional versatility in the CRP-FNR superfamily of transcription factors: FNR and FLP.

Jeffrey Green, J. Guest, C. Scott, 2001, Advances in microbial physiology.

A revised biosynthetic pathway for the cofactor F420 in prokaryotes

N. Tokuriki, E. Baker, B. Palmer, 2019, Nature Communications.

300-Fold Increase in Production of the Zn2+-Dependent Dechlorinase TrzN in Soluble Form via Apoenzyme Stabilization

M. Field, J. Oakeshott, R. Russell, 2014, Applied and Environmental Microbiology.

Landguard(TM) A900. An enzyme-based remediant for the detoxification of organophosphate insecticides in animal dips

C. Scott, 2012 .

Form via Apoenzyme Stabilization-Dependent Dechlorinase TrzN in Soluble 2 + 300-Fold Increase in Production of the Zn

M. Field, R. Russell, J. Newman, 2014 .

Miscoordination of the Iron-Sulfur Clusters of the Anaerobic Transcription Factor, FNR, Allows Simple Repression but Not Activation*

Jeffrey Green, C. Scott, 2002, The Journal of Biological Chemistry.

Anaerobic acquisition of [4Fe 4S] clusters by the inactive FNR(C20S) variant and restoration of activity by second‐site amino acid substitutions

Peter C. Jordan, P. Jordan, Jeffrey Green, 2001, Molecular microbiology.

Non-covalent binding tags for batch and flow biocatalysis.

P. Hands, R. Speight, C. Scott, 2023, Enzyme and microbial technology.

Over the rainbow: structural characterization of the chromoproteins gfasPurple, amilCP, spisPink and eforRed

J. Newman, T. Peat, A. Warden, 2022, Acta Crystallographica Section D: Structural Biology.

Determination of the Structure of the Catabolic N-Succinylornithine Transaminase (AstC) from Escherichia coli

Shane A. Seabrook, J. Newman, T. Peat, 2013, PloS one.

Zinc uptake, oxidative stress and the FNR-like proteins of Lactococcus lactis.

C. Shearman, M. Gasson, Jeffrey Green, 2000, FEMS microbiology letters.

300-Fold Increase in Production of the Zn2+-Dependent Dechlorinase TrzN in Soluble Form via Apoenzyme Stabilization

M. Field, J. Oakeshott, R. Russell, 2014, Applied and Environmental Microbiology.

OpdA, a bacterial organophosphorus hydrolase, prevents lethality in rats after poisoning with highly toxic organophosphorus pesticides.

J. Oakeshott, T. Sutherland, M. Eddleston, 2008, Toxicology.

Crystal structure of a putrescine aminotransferase from Pseudomonas sp. strain AAC.

J. Newman, T. Peat, C. Scott, 2017, Acta crystallographica. Section F, Structural biology communications.

Hacking nature: genetic tools for reprograming enzymes

C. Scott, M. Wilding, C. Hartley, 2017 .