G. Carter

发表

Biosynthesis of the immunosuppressants FK506, FK520, and rapamycin involves a previously undescribed family of enzymes acting on chorismate

Christine J. Martin, Teresa A. Foster, M. Gregory, 2011, Proceedings of the National Academy of Sciences.

Aplidiasphingosine, an antimicrobial and antitumor terpenoid from an Aplidium species (marine tunicate)

K. Rinehart, G. Carter, 1978 .

The evolving role of natural products in drug discovery

F. Koehn, G. Carter, 2005, Nature Reviews Drug Discovery.

Rapid cloning and heterologous expression of the meridamycin biosynthetic gene cluster using a versatile Escherichia coli-streptomyces artificial chromosome vector, pSBAC.

E. Graziani, Hao-Tian Jiang, F. Koehn, 2009, Journal of natural products.

Structures of the muraymycins, novel peptidoglycan biosynthesis inhibitors.

R. Williamson, M. Siegel, G. Carter, 2002, Journal of the American Chemical Society.

FTMS structure elucidation of natural products: application to muraymycin antibiotics using ESI multi-CHEF SORI-CID FTMS(n), the top-down/bottom-up approach, and HPLC ESI capillary-skimmer CID FTMS.

G. Kruppa, M. Siegel, G. Carter, 2003, Analytical chemistry.

Pharmaceutical profiling method for lipophilicity and integrity using liquid chromatography-mass spectrometry.

Li Di, Edward H Kerns, Teresa Kleintop, 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

High throughput artificial membrane permeability assay for blood-brain barrier.

Li Di, Edward H Kerns, K. Fan, 2003, European journal of medicinal chemistry.

Circulocins, new antibacterial lipopeptides from Bacillus circulans, J2154

G. Carter, Hai-yin He, B. Shen, 2001 .

Enantiomeric separation and determination of absolute stereochemistry of asymmetric molecules in drug discovery: building chiral technology toolboxes.

K. Fan, R. Williamson, V. Marathias, 2007, Chirality.

Structural validation of saccharomicins by high resolution and high mass accuracy fourier transform-ion cyclotron resonance-mass spectrometry and infrared multiphoton dissociation tandem mass spectrometry

A. Marshall, M. Siegel, C. Hendrickson, 1999 .

Mannopeptimycins, novel antibacterial glycopeptides from Streptomyces hygroscopicus, LL-AC98.

R. Williamson, S. Sakya, E. Graziani, 2002, Journal of the American Chemical Society.

Mannopeptimycin esters and carbonates, potent antibiotic agents against drug-resistant bacteria.

F. Koehn, G. Carter, P. Petersen, 2004, Bioorganic & medicinal chemistry letters.

New Micropeptins with Anti-Neuroinflammatory Activity Isolated from a Cyanobacterial Bloom

G. Carter, M. Bertin, Shibiao Wu, 2021, ACS omega.

Novel sulfur-containing rapamycin analogs prepared by precursor-directed biosynthesis.

E. Graziani, G. Carter, M. Summers, 2003, Organic letters.

Isolation and Structural Elucidation of AC326-α, A New Member of the Moenomycin Group

M. Siegel, G. Carter, Hai-yin He, 2000 .

Discovery and assembly-line biosynthesis of the lymphostin pyrroloquinoline alkaloid family of mTOR inhibitors in Salinispora bacteria.

B. Moore, P. Jensen, F. Koehn, 2011, Journal of the American Chemical Society.

New Strategies for Natural Products Lead Generation

F. Koehn, G. Carter, V. Bernan, 2010 .

Biosynthesis of diazepinomicin/ECO-4601, a Micromonospora secondary metabolite with a novel ring system.

C. Farnet, G. Carter, Xidong Feng, 2008, Journal of natural products.

In vitro solubility assays in drug discovery.

L. Di, G. Carter, E. Kerns, 2008, Current drug metabolism.

Cell wall active antifungal compounds produced by the marine fungus Hypoxylon oceanicum LL-15G256. II. Isolation and structure determination.

G. Carter, D. Williams, G. Schlingmann, 1998, The Journal of antibiotics.

Pseudopyronines A and B, α-Pyrones Produced by a Marine Pseudomonas sp. F92S91, and Evidence for the Conversion of 4-Hydroxy-α-pyrone to 3-Furanone

G. Carter, M. P. Singh, Fangming Kong, 2005 .

Pseudopyronines A and B, alpha-pyrones produced by a marine Pseudomonas sp. F92S91, and evidence for the conversion of 4-hydroxy-alpha-pyrone to 3-furanone.

G. Carter, M. P. Singh, Fangming Kong, 2005, Journal of natural products.

NP/MS since 1970: from the basement to the bench top.

G. Carter, 2014, Natural product reports.

Recent applications of mass spectrometry to antibiotic research

M. Siegel, G. Carter, D. Borders, 1985 .

Applications of high throughput microsomal stability assay in drug discovery.

L. Di, G. Carter, Youping Huang, 2008, Combinatorial chemistry & high throughput screening.

Probing natural product biosynthetic pathways using Fourier transform ion cyclotron resonance mass spectrometry.

F. Koehn, G. Carter, Xidong Feng, 2009, Bioorganic & medicinal chemistry.

New α-pyrones produced by fungal culture LL-11G219 function as androgen receptor ligands

G. Carter, G. Schlingmann, L. Milne, 1998 .

Septocylindrins A and B: peptaibols produced by the terrestrial fungus Septocylindrium sp. LL-Z1518.

E. Graziani, M. Siegel, G. Carter, 2007, Journal of natural products.

Circulocins, New Antibacterial Lipopeptides from Bacillus circulans, J2154

G. Carter, Hai-yin He, B. Shen, 2001 .

Pyrrocidines A and B, new antibiotics produced by a filamentous fungus

G. Carter, R. Bigelis, Hai-yin He, 2002 .

Investigating the biosynthetic origin of the nitro group in pyrrolomycins.

G. Carter, B. Haltli, Xidong Feng, 2008, Journal of natural products.

Structure determination of glycinocins A to D, further evidence for the cyclic structure of the amphomycin antibiotics.

G. Carter, Fangming Kong, 2003, The Journal of antibiotics.

Structure characterization of lipocyclopeptide antibiotics, aspartocins A, B & C, by ESI-MSMS and ESI-nozzle-skimmer-MSMS.

M. Siegel, G. Carter, Xidong Feng, 2009, Journal of mass spectrometry : JMS.

Lomaiviticins A and B, potent antitumor antibiotics from Micromonospora lomaivitiensis.

A. Richardson, C. Ireland, G. Carter, 2001, Journal of the American Chemical Society.

Plasma membrane protection against the acute effects of inorganic lead on the respiratory rates of intact liver cells.

G. Carter, B. Horwitz, J. Guttas, 1983, Journal of toxicology and environmental health.

Evaluating indole-related derivatives as precursors in the directed biosynthesis of diazepinomicin analogues.

G. Carter, Xidong Feng, J. Janso, 2009, Journal of natural products.

Diazepinomicin, a new antimicrobial alkaloid from a marine Micromonospora sp.

G. Carter, Xidong Feng, J. Janso, 2004, Journal of natural products.

Structures of the muraymycins, novel peptidoglycan biosynthesis inhibitors.

R. Williamson, M. Siegel, G. Carter, 2002, Journal of the American Chemical Society.

Mining Marine Microorganisms as a Source of New Antimicrobials and Antifungals

G. Carter, M. Greenstein, V. Bernan, 2004 .

Taxonomy and Biological Activities

G. Carter, P. Petersen, W. Weiss, 2008 .

Acremonidins, new polyketide-derived antibiotics produced by Acremonium sp., LL-Cyan 416.

G. Carter, R. Bigelis, Hai-yin He, 2003, The Journal of antibiotics.

Uridyl Peptide Antibiotics: Developments in Biosynthesis and Medicinal Chemistry

G. Carter, L. McDonald, 2014 .

Discovery of anabaenopeptin 679 from freshwater algal bloom material: Insights into the structure-activity relationship of anabaenopeptin protease inhibitors.

Roger G. Linington, Kenji L. Kurita, A. Kinghorn, 2016, Bioorganic & Medicinal Chemistry Letters.

Saccharomicins, Novel Heptadecaglycoside Antibiotics Effective against Multidrug-Resistant Bacteria

M. Siegel, F. Koehn, G. Carter, 1998 .

Lomaiviticins A and B, potent antitumor antibiotics from Micromonospora lomaivitiensis.

A. Richardson, C. Ireland, G. Carter, 2001, Journal of the American Chemical Society.

Hongoquercins A and B, new sesquiterpenoid antibiotics: isolation, structure elucidation, and antibacterial activity.

G. Carter, D. Roll, J. Manning, 1998, The Journal of antibiotics.

Isolation, characterization and structure of a new allenic polyine antibiotic produced by fungus LL-07F275.

C. Pearce, G. Carter, D. Borders, 1995, The Journal of antibiotics.

Chloroquinocin, a novel chlorinated naphthoquinone antibiotic from Streptomyces sp., LL-A9227.

G. Carter, Hai-yin He, Hui Y. Yang, 2002, The Journal of antibiotics.

Harnessing the biosynthetic capacity of marine-derived organisms.

G. Carter, P. Crews, 2011, Bioorganic & medicinal chemistry.

Dictyosphaeric acids A and B: new decalactones from an undescribed Penicillium sp. obtained from the alga Dictyosphaeria versluyii.

R. Williamson, C. Ireland, T. Bugni, 2004, Journal of natural products.

Structural elucidation of lemonomycin, a potent antibiotic from Streptomyces candidus

G. Carter, Hai-yin He, B. Shen, 2000 .

Production of Novel Rapamycin Analogs by Precursor-Directed Biosynthesis

E. Graziani, G. Carter, M. Summers, 2005, Applied and Environmental Microbiology.

Microcionamides A and B, bioactive peptides from the philippine sponge Clathria (Thalysias) abietina.

M. K. Harper, C. Ireland, D. Taşdemir, 2004, The Journal of organic chemistry.

Colubricidin A, a novel macrolide antibiotic from a Streptomyces sp.

G. Carter, M. Tischler, Fangming Kong, 1999 .

Martinomycin, a new polyether antibiotic produced by Streptomyces salvialis. I. Taxonomy, fermentation and biological activity.

C. Pearce, G. Carter, D. Montenegro, 1994, The Journal of antibiotics.

The effect of methylation inhibitors on citreamicin biosynthesis in Micromonospora citrea.

C. Pearce, G. Carter, D. Borders, 1991, The Journal of antibiotics.

Citreamicins, novel antibiotics from Micromonospora citrea: isolation, characterization, and structure determination.

G. Carter, D. Williams, D. Borders, 1990, The Journal of antibiotics.

Structural determination of mannopeptimycin cyclic acetals

F. Koehn, G. Carter, Xidong Feng, 2004 .

Hygrocins a and B, naphthoquinone macrolides from Streptomyces hygroscopicus.

Greg F. Glasier, P. Cai, G. Carter, 2005, Journal of natural products.

LL-F28249 antibiotic complex: a new family of antiparasitic macrocyclic lactones. Isolation, characterization and structures of LL-F28249 alpha, beta, gamma, lambda.

M. Siegel, G. Carter, D. Williams, 1988, The Journal of antibiotics.

Structure determination of LL-F28249α, β, γ, and λ, potent antiparasitic macrolides from Streptomyces cyaneogriseus ssp. noncyanogenus

G. Carter, D. Borders, J. A. Nietsche, 1987 .

Isolation and identification of antifungal polyesters from the marine fungus Hypoxylon oceanicum LL-15G256

G. Carter, G. Schlingmann, L. Milne, 2002 .

Absolute stereochemistry of the spiroxins

K. Nakanishi, N. Berova, G. Carter, 2001 .

Spiroxins, DNA cleaving antitumor antibiotics from a marine-derived fungus

C. Discafani, G. Carter, L. McDonald, 1999 .

Biosynthesis of ravidomycin. Use of 13C-13C double quantum NMR to follow precursor incorporation

G. Carter, Richard J. White, D. Borders, 1984 .

Making the most of Papua New Guinea’s biodiversity: Establishment of an integrated set of programs that link botanical survey with pharmacological assessment in “the land of the unexpected”

M. K. Harper, J. Jensen, C. Ireland, 2009, Pharmaceutical biology.

Reassessing the structure of pyranonigrin.

N. Berova, F. Koehn, G. Carter, 2007, Journal of natural products.

Insecticidal and synergistic components isolated from dill plants.

K. R. Schulz, G. Carter, H. Schnoes, 1974, Journal of agricultural and food chemistry.

Structure determination of simaomicins α and β, extremely potent, novel anticoccidal agents produced by Actinomadura

G. Carter, D. Borders, T. Lee, 1989 .

Fumaquinone, a New Prenylated Naphthoquinone from Streptomyces fumanus

G. Carter, Xidong Feng, G. Schlingmann, 2005, The Journal of Antibiotics.

Structures of the Aspartocin Antibiotics §-A Consideration of Requirements for Cyclopeptide Structures

G. Carter, Fangming Kong, J. Ashcroft, 2010 .

The identification of a gene family in the Saccharomyces cerevisiae ergosterol biosynthesis pathway.

M. Goebl, M. Bard, G. Carter, 1994, Gene.

Normal-phase automated mass-directed HPLC purification of a pyrrolobenzodiazepine library with vasopressin agonist activity.

G. Carter, O. Mcconnell, A. Failli, 2009, Journal of combinatorial chemistry.

Marine natural products as sources of antiviral, antimicrobial, and antineoplastic agents

Judith L. Connor, R. G. Hughes, K. Rinehart, 1981 .

THE EFFECT OF METHYLATION INHIBITORS ON CITREAMICIN

C. Pearce, G. Carter, D. Borders, 2006 .

07H239-A, a new cytotoxic eremophilane sesquiterpene from the marine-derived Xylariaceous fungus LL-07H239.

P. Lassota, G. Carter, L. McDonald, 2004, Journal of natural products.

Pyrrocidines A and B, New Antibiotics Produced by a Filamentous Fungus.

G. Carter, R. Bigelis, Hai-yin He, 2002 .

Acarnidines, novel antiviral and antimicrobial compounds from the sponge Acarnus erithacus (de Laubenfels)

K. Rinehart, G. Carter, 1978 .

Natural products and Pharma 2011: strategic changes spur new opportunities.

G. Carter, Guy T Carter, 2011, Natural product reports.

Aplidiasphingosine, an antimicrobial and antitumor terpenoid from an Aplidium species (marine tunicate)

K. Rinehart, G. Carter, 1978 .

Structure and absolute stereochemistry of 21-hydroxyoligomycin A.

R. Williamson, G. Carter, D. Ho, 2007, Journal of Natural Products.

Absolute stereochemistry of the strevertenes.

K. Nakanishi, N. Berova, G. Carter, 2000, Chirality.

Structure determination of oligomycins A and C

G. Carter, 1986 .

Echinosporamicin, a New Antibiotic Produced by Micromonospora echinospora ssp. echinospora, LL-P175

G. Carter, Hai-yin He, Hui Y. Yang, 2004 .

Martinomycin, a new polyether antibiotic produced by Streptomyces salvialis. II. Isolation and structure determination.

G. Carter, D. Williams, D. Borders, 1994, The Journal of antibiotics.

Cytosporacin, a highly unsaturated polyketide: application of the ACCORD-ADEQUATE experiment to the structural determination of natural products.

R. Williamson, G. Carter, J. Janso, 2003, The Journal of organic chemistry.

Biosynthetic origin of the carbon skeleton and oxygen atoms of the LL-F28249 alpha, a potent antiparasitic macrolide.

G. Carter, H. Tsou, D. Borders, 1989, The Journal of antibiotics.

Strevertenes, antifungal pentaene macrolides produced by Streptoverticillcum LL-30F848

G. Carter, D. Borders, G. Schlingmann, 1999 .

Cyanobufalins: Cardioactive Toxins from Cyanobacterial Blooms.

P. Moeller, P. Zimba, G. Carter, 2018, Journal of natural products.

In Vitro Permeability of Poorly Aqueous Soluble Compounds Using Different Solubilizers in the PAMPA Assay with Liquid Chromatography/Mass Spectrometry Detection

A. Avdeef, G. Carter, M. Tischler, 2003, Pharmaceutical Research.

Biosynthesis of chrysomycins A and B. Origin of the chromophore.

G. Carter, R. White, Richard J. White, 1985, The Journal of antibiotics.

Natural Products: Natural Products: Discourse, Diversity, and Design

A. Osbourn, G. Carter, R. Goss, 2014 .

Natural products : discourse, diversity and design

Anne Osbourn, Guy T. Carter, A. Osbourn, 2014 .

Biosynthetic Potential of Phylogenetically Unique Endophytic Actinomycetes from Tropical Plants

G. Carter, J. Janso, 2010, Applied and Environmental Microbiology.

Rediscovering natural products as a source of new drugs.

F. Koehn, G. Carter, 2005, Discovery medicine.

Anticancer Agents from Unique Natural Products Sources

M. K. Harper, T. Fojo, R. Andersen, 2003 .

Discovery of the lomaiviticin biosynthetic gene cluster in Salinispora pacifica.

Li Zha, Hitomi Nakamura, Frank E Koehn, 2014, Tetrahedron.

Creating an Antiviral Arsenal for Epidemic Preparedness

G. Carter, Ross O. Youngs, R. Nemade, 2020 .

ADMET In Vitro Profiling: Utility and Applications in Lead Discovery

L. Di, G. Carter, E. Kerns, 2010 .

Strategies to assess blood–brain barrier penetration

Li Di, Edward H Kerns, L. Di, 2008, Expert opinion on drug discovery.

Direct high-performance liquid chromatographic separation of the enantiomers of venlafaxine and 11 analogs using amylose-derived chiral stationary phases.

G. Carter, S. Caccamese, Salvatore Bianca, 2009, Chirality.

Direct high-performance liquid chromatographic separation of the enantiomers of an aromatic amine and four aminoalcohols using polysaccharide chiral stationary phases and acidic additive.

G. Carter, S. Caccamese, Salvatore Bianca, 2007, Chirality.

Absolute stereochemistry of the diepoxins

K. Nakanishi, N. Berova, S. Matile, 1996 .

Diepoxins, novel fungal metabolites with antibiotic activity

R. West, C. Pearce, G. Carter, 1993 .

In support of the original medermycin/lactoquinomycin A structure.

R. Williamson, G. Carter, L. McDonald, 2002, Organic letters.

Binding of rapamycin analogs to calcium channels and FKBP52 contributes to their neuroprotective activities

M. Pangalos, B. Ruan, J. Skotnicki, 2008, Proceedings of the National Academy of Sciences.

Chapter 5:Progress in Enhancing the Neurotrophic Effects of Natural FKBP Ligands

G. Carter, 2012 .

Diversity oriented biosynthesis via accelerated evolution of modular gene clusters

Christine J. Martin, Lesley S. Sheehan, M. Gregory, 2017, Nature Communications.

Novel alpha-pyrones produced by a marine Pseudomonas sp. F92S91: taxonomy and biological activities.

G. Carter, P. Petersen, W. Weiss, 2003, The Journal of antibiotics.

Oxasetin, a new antibacterial polyketide produced by fungus Vaginatispora aquatica, HK1821.

G. Carter, M. P. Singh, J. Janso, 2002, The Journal of antibiotics.

Use of a linear gradient flow program for liquid chromatography-mass spectrometry protein-binding studies.

Mark Tischler, Chantel Sabus, G. Carter, 2002, Journal of chromatography. A.

Peak homogeneity determination for the validation of high-performance liquid chromatographic assay methods.

G. Carter, H. Burke, R. E. Schiesswohl, 1982, Journal of pharmaceutical sciences.

Recombinant strains for the enhanced production of bioengineered rapalogs.

Christine J. Martin, Teresa A. Foster, M. Gregory, 2013, Metabolic engineering.

The structure of V214w from an unidentified fungus.

R. Williamson, G. Carter, M. Tischler, 2002, The Journal of antibiotics.

Isolation of Pyrrolocins A–C: cis- and trans-Decalin Tetramic Acid Antibiotics from an Endophytic Fungal-Derived Pathway

L. Barrows, E. Schmidt, G. Carter, 2014, Journal of natural products.

Biosynthetic origin of the carbon skeleton of simaomicin α, a hexacyclic xanthone antibiotic

S. Gould, G. Carter, D. Borders, 1989 .

Biosynthetic origins of the polycyclic xanthone antibiotic, citreamicin

C. Pearce, G. Carter, D. Borders, 1991 .

Biosynthetic Origins of the Polycyclic Xanthone Antibiotic, Citreamicin.

C. Pearce, G. Carter, D. Borders, 1991 .

Additional pyrrolomycins from cultures of Streptomyces fumanus.

G. Carter, Xidong Feng, G. Schlingmann, 2005, Journal of Natural Products.

Drug-like property concepts in pharmaceutical design.

Li Di, Edward H Kerns, L. Di, 2009, Current pharmaceutical design.

4-Methoxy-2-(trans-1-propenyl)phenyl (±)-2-methylbutanoate from anise plants

G. Carter, H. Schnoes, E. Lichtenstein, 1977 .

Remisporine B, a novel dimeric chromenone derived from spontaneous Diels–Alder reaction of remisporine A

G. Carter, Fangming Kong, 2003 .

Saccharomicins, Novel Heptadecaglycoside Antibiotics Effective Against Multidrug‐Resistant Bacteria.

M. Siegel, F. Koehn, G. Carter, 1999 .

New biotransformation products of nemadectins.

G. Carter, G. Schlingmann, A. Enos, 2001, The Journal of antibiotics.

Immobilized artificial membrane chromatography with mass spectrometric detection: a rapid method for screening drug-membrane interactions.

G. Carter, M. Tischler, H. Liu, 2001, Rapid communications in mass spectrometry : RCM.

Determination of the absolute stereochemistry of nemadectins .alpha.2 and .alpha.

K. Nakanishi, N. Berova, L. Lo, 1992 .

Marine natural products in Pharma: how industry missed the boat

Guy T. Carter, Valerie S. Bernan, G. Carter, 2016 .

Comparison of cytochrome P450 inhibition assays for drug discovery using human liver microsomes with LC-MS, rhCYP450 isozymes with fluorescence, and double cocktail with LC-MS.

Li Di, Edward H Kerns, L. Di, 2007, International journal of pharmaceutics.

LL-F42248 alpha, a novel chlorinated pyrrole antibiotic.

G. Carter, T. S. Dunne, D. Borders, 1987, The Journal of antibiotics.

NewBiotransformation Products of Nemadectins

G. Carter, G. Schlingmann, Kan FANGa, 2006 .

Sensitive liquid chromatographic method for the determination of a specific M1 agonist, LY246708, an investigational agent with potential for the treatment of Alzheimer's disease, in human plasma.

G. Carter, J. A. Kirkwood, C. L. Hamilton, 1993, Journal of chromatography.

Diversity oriented biosynthesis via accelerated evolution of modular gene clusters

Markiyan Samborskyy, Mohammad Nur-E-Alam, Alexander Alanine, 2017, Nature Communications.

LL-E19020 alpha and beta, novel growth promoting agents: isolation, characterization and structures.

G. Carter, T. S. Dunne, D. Borders, 1988, The Journal of antibiotics.

Relative and absolute configurations of ganefromycin alpha.

K. Nakanishi, N. Berova, G. Carter, 2000, Organic letters.

Base-catalyzed isomerism in elfamycin antibiotics. Structures of ganefromycins epsilon and epsilon 1.

R. West, G. Carter, M. Tischler, 1995, The Journal of antibiotics.

Process-scale reversed-phase high-performance liquid chromatography purification of LL-E19020 alpha, a growth promoting antibiotic produced by Streptomyces lydicus ssp. tanzanius.

G. Carter, D. Williams, D. Borders, 1989, Journal of chromatography.

Base-catalyzed Isomerism in Elfamycin Antibiotics Structures of Ganefromycins s and sx

R. West, G. Carter, M. Tischler, 2006 .

The effect of sinefungin on the biosynthesis of ganefromycin. Structures of ganefromycins δ1–4

R. West, C. Pearce, G. Carter, 1995 .

Chemistry and structure of ganefromycin

R. West, G. Carter, D. Borders, 1993 .

Relative and Absolute Configurations of Ganefromycin α.

K. Nakanishi, N. Berova, G. Carter, 2000 .

Chemistry and Structure of Ganefromycin.

R. West, G. Carter, D. Borders, 1994 .

NP/MS since 1970: from the basement to the bench top.

G. Carter, 2014, Natural product reports.

Computer-based system for correlating molecular structures with mass spectral data Methods for generating molecular substructures and for incorporating fragmentation rules

N. Bauman, M. Siegel, G. Carter, 1986 .