Q. Ye

发表

p-Aminobenzoate synthesis in Escherichia coli: purification and characterization of PabB as aminodeoxychorismate synthase and enzyme X as aminodeoxychorismate lyase.

J. Liu, C. Walsh, Q. Ye, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Contribution of the C-terminal domain of metalloproteinases to binding by tissue inhibitor of metalloproteinases. C-terminal truncated stromelysin and matrilysin exhibit equally compromised binding affinities as compared to full-length stromelysin.

Q. Ye, J. Shipley, H. Welgus, 1994, The Journal of biological chemistry.

Calcium stoichiometry determination for calcium binding proteins by electrospray ionization mass spectrometry.

J. Loo, Q. Ye, P. Hu, 1994, Analytical chemistry.

Estimating the number of viable animal cells in multiwell culture--a tetrazolium-based assay.

Q. Ye, M. Richter, G. Haslam, 2005, Analytical biochemistry.

A high-throughput FRET-based assay for determination of Atg4 activity

X. Chen, Xiao-Ming Yin, Q. Ye, 2012, Autophagy.

Analysis of the stoichiometric metal activation of methionine aminopeptidase

S. Chai, Q. Ye, 2009, BMC Biochemistry.

High-throughput screening for Hsp90 ATPase inhibitors.

B. Blagg, Q. Ye, M. K. Hadden, 2006, Bioorganic & medicinal chemistry letters.

Rapid, accurate and sensitive determination of molecular weight of 15N and 13C labeled recombinant p

Q. Ye, V. Thanabal, T. Heath, 1993 .

Growth inhibition of Escherichia coli and methicillin-resistant Staphylococcus aureus by targeting cellular methionine aminopeptidase.

S. Chai, Q. Ye, Derong Ding, 2011, European journal of medicinal chemistry.

Identification of potent type I MetAP inhibitors by simple bioisosteric replacement. Part 1: Synthesis and preliminary SAR studies of thiazole-4-carboxylic acid thiazol-2-ylamide derivatives.

F. Nan, Q. Ye, Jia Li, 2005, Bioorganic & medicinal chemistry letters.

Specificity for inhibitors of metal-substituted methionine aminopeptidase.

F. Nan, Jia Li, Q. Ye, 2003, Biochemical and biophysical research communications.

Purification and characterization of catalytic domains of gelatinase A with or without fibronectin insert for high-throughput inhibitor screening.

F. Nan, Q. Ye, Q. Shen, 2003, Protein expression and purification.

Ionic immobilization, diversification, and release: application to the generation of a library of methionine aminopeptidase inhibitors.

G. Georg, G. Lushington, Benjamin Neuenswander, 2008, Journal of combinatorial chemistry.

Catalytic Activities and Substrate Specificity of the Human Membrane Type 4 Matrix Metalloproteinase Catalytic Domain*

R. D. Dyer, Q. Ye, R. Dyer, 1999, The Journal of Biological Chemistry.

Purification and characterization of the human stromelysin catalytic domain expressed in Escherichia coli.

D. Hupe, Q. Ye, V. Baragi, 1992, Biochemistry.

Molecular biology of carbon-phosphorus bond cleavage. Cloning and sequencing of the phn (psiD) genes involved in alkylphosphonate uptake and C-P lyase activity in Escherichia coli B.

C. Walsh, B. Wanner, Q. Ye, 1990, The Journal of biological chemistry.

N1-(3-Cyclohexylbutanoyl)-N2-[3-(1H-imidazol-4-yl)propyl]guanidine (UR-AK57), a Potent Partial Agonist for the Human Histamine H1- and H2-Receptors

R. Seifert, A. Buschauer, S. Xie, 2006, Journal of Pharmacology and Experimental Therapeutics.

N 1-( 3-Cyclohexylbutanoyl )-N 2-[ 3-( 1 H-imidazol-4-yl ) propyl ] guanidine ( UR-AK 57 ) , a Potent Partial Agonist for the Human Histamine H 1-and H 2-Receptors

R. Seifert, A. Buschauer, S. Xie, 2006 .

Stereochemistry of carbon-phosphorus cleavage in ethylphosphonate catalyzed by C-P lyase from Escherichia coli

C. Walsh, Hyeongjin Cho, Y. Ahn, 1992 .

Inhibitors of type I MetAPs containing pyridine-2-carboxylic acid thiazol-2-ylamide. Part 2: SAR studies on the pyridine ring 3-substituent.

F. Nan, Q. Ye, Jia Li, 2005, Bioorganic & medicinal chemistry letters.

Identification and characterization of novel isothiazolones with potent bactericidal activity against multi-drug resistant Acinetobacter baumannii clinical isolates.

Q. Ye, H. H. Xu, P. Ewing, 2019, International journal of antimicrobial agents.

Discovery and structural modification of inhibitors of methionine aminopeptidases from Escherichia coli and Saccharomyces cerevisiae.

F. Nan, G. Lushington, Q. Ye, 2003, Journal of medicinal chemistry.

Metalloform-selective inhibitors of escherichia coli methionine aminopeptidase and X-ray structure of a Mn(II)-form enzyme complexed with an inhibitor.

S. Xie, Q. Ye, Ze-Qiang Ma, 2004, Journal of the American Chemical Society.

Discovery and development of the covalent hydrates of trifluoromethylated pyrazoles as riboflavin synthase inhibitors with antibiotic activity against Mycobacterium tuberculosis.

Markus Fischer, Qi-Zhuang Ye, Yujie Zhao, 2009, The Journal of organic chemistry.

Synthesis and structure-function analysis of Fe(II)-form-selective antibacterial inhibitors of Escherichia coli methionine aminopeptidase.

S. Chai, Q. Ye, Wen-Long Wang, 2009, Bioorganic & medicinal chemistry letters.

Studies towards the synthesis of methionine aminopeptidase inhibitors: diversification utilizing a ROMP-derived coupling reagent.

G. Georg, G. Lushington, Q. Ye, 2008, Journal of combinatorial chemistry.

Metalloform-selective inhibition: synthesis and structure-activity analysis of Mn(II)-form-selective inhibitors of Escherichia coli methionine aminopeptidase.

F. Nan, Q. Ye, Min Huang, 2005, Bioorganic & medicinal chemistry letters.

Rotational resonance determination of the structure of an enzyme-inhibitor complex: phosphorylation of an (aminoalkyl)phosphinate inhibitor of D-alanyl-D-alanine ligase by ATP.

C. Walsh, R. Griffin, A. McDermott, 1990, Biochemistry.

Characterization of full length and truncated type I human methionine aminopeptidases expressed from Escherichia coli.

M. Gu, F. Nan, Q. Ye, 2004, Biochemistry.

Mutations at the S1 Sites of Methionine Aminopeptidases from Escherichia coli and Homo sapiens Reveal the Residues Critical for Substrate Specificity*

M. Gu, F. Nan, Q. Ye, 2004, Journal of Biological Chemistry.

Catalysis and inhibition of Mycobacterium tuberculosis methionine aminopeptidase.

S. Chai, Q. Ye, Jing-Ping Lu, 2010, Journal of medicinal chemistry.

Metalloform-Selective Inhibition: Synthesis and Structure—Activity Analysis of Mn(II)-Form-Selective Inhibitors of Escherichia coli Methionine Aminopeptidase.

F. Nan, Q. Ye, Min Huang, 2006 .

Metal mediated inhibition of methionine aminopeptidase by quinolinyl sulfonamides.

S. Xie, Q. Ye, Ze-Qiang Ma, 2006, Biochemical and biophysical research communications.

Tiki1 Is Required for Head Formation via Wnt Cleavage-Oxidation and Inactivation

Chika Yokota, Hanno Steen, Mingzi M. Zhang, 2012, Cell.

Structural analysis of bengamide derivatives as inhibitors of methionine aminopeptidases.

Wei Xu, Q. Ye, Jing-Ping Lu, 2012, Journal of medicinal chemistry.

A novel lumazine synthase inhibitor derived from oxidation of 1,3,6,8-tetrahydroxy-2,7-naphthyridine to a tetraazaperylenehexaone derivative.

A. Bacher, M. Fischer, G. Georg, 2007, The Journal of organic chemistry.

X-ray structure of a hydroxamate inhibitor complex of stromelysin catalytic domain and its comparison with members of the zinc metalloproteinase superfamily.

T L Blundell, T. Blundell, C. Humblet, 1996, Structure.

High-throughput assay for the identification of Hsp90 inhibitors based on Hsp90-dependent refolding of firefly luciferase.

B. Blagg, R. Matts, B. Yun, 2007, Bioorganic & medicinal chemistry.

Discovery of inhibitors of Escherichia coli methionine aminopeptidase with the Fe(II)-form selectivity and antibacterial activity.

S. Chai, Q. Ye, T. Hurley, 2008, Journal of medicinal chemistry.

Structural basis of catalysis by monometalated methionine aminopeptidase.

S. Xie, Q. Ye, Ze-Qiang Ma, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Assignments for the main-chain nuclear magnetic resonances and delineation of the secondary structure of the catalytic domain of human stromelysin-1 as obtained from triple-resonance 3D NMR experiments.

D. Hupe, E. Zuiderweg, S. V. Van Doren, 1993, Biochemistry.

The Structural Basis for the Elastolytic Activity of the 92-kDa and 72-kDa Gelatinases

Qi-Zhuang Ye, S. Shapiro, R. Senior, 1996, The Journal of Biological Chemistry.

X-RAY STRUCTURE OF GELATINASE A CATALYTIC DOMAIN COMPLEXED WITH A HYDROXAMATE INHIBITOR

Tom L. Blundell, Christine Humblet, Daniel F. Ortwine, 1999 .

FE(II) Is the Native Cofactor for Escherichia coli Methionine Aminopeptidase*

S. Chai, Q. Ye, Wen-Long Wang, 2008, Journal of Biological Chemistry.

A high-throughput screen utilizing the fluorescence of riboflavin for identification of lumazine synthase inhibitors.

A. Bacher, M. Fischer, G. Georg, 2005, Analytical biochemistry.

Discovery and development of a small molecule library with lumazine synthase inhibitory activity.

A. Bacher, M. Fischer, G. Georg, 2009, The Journal of organic chemistry.

X‐ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: Implications for inhibitor selectivity

T. Blundell, M. Williams, C. Humblet, 1999, Protein science : a publication of the Protein Society.

Two methionine aminopeptidases from Acinetobacter baumannii are functional enzymes.

S. Chai, Q. Ye, C. K. Lam, 2011, Bioorganic & medicinal chemistry letters.

Determination of binding affinity of metal cofactor to the active site of methionine aminopeptidase based on quantitation of functional enzyme.

S. Chai, Q. Ye, Jing-Ping Lu, 2009, Analytical biochemistry.

Metal-mediated inhibition is a viable approach for inhibiting cellular methionine aminopeptidase.

S. Chai, Q. Ye, 2009, Bioorganic & medicinal chemistry letters.

Inhibition of monometalated methionine aminopeptidase: inhibitor discovery and crystallographic analysis.

F. Nan, S. Xie, Q. Ye, 2007, Journal of medicinal chemistry.

Structural analysis of metalloform-selective inhibition of methionine aminopeptidase.

S. Xie, Q. Ye, Wei Huang, 2006, Acta crystallographica. Section D, Biological crystallography.

Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives

S. Franzblau, Q. Ye, B. Wan, 2011, ChemMedChem.

Solution structure of the catalytic domain of human stromelysin complexed with a hydrophobic inhibitor

D. Hupe, E. Zuiderweg, S. V. Van Doren, 1995, Protein science : a publication of the Protein Society.

Reconstructed 19 kDa catalytic domain of gelatinase A is an active proteinase.

D. Hupe, Q. Ye, L. Johnson, 1995, Biochemistry.

Support Vector Machines in HTS Data Mining: Type I MetAPs Inhibition Study

Jianwen Fang, Yinghua Dong, Gunda I Georg, 2006, Journal of biomolecular screening.

Zinc content of promatrilysin, matrilysin and the stromelysin catalytic domain.

H. V. Van Wart, Q. Ye, D. Auld, 1994, Biochemical and biophysical research communications.

Gene synthesis and expression in E. coli for pump, a human matrix metalloproteinase.

Q. Ye, V. Baragi, L. Johnson, 1992, Biochemical and biophysical research communications.

A recombinant human stromelysin catalytic domain identifying tryptophan derivatives as human stromelysin inhibitors.

D. Hupe, Q. Ye, L. Johnson, 1994, Journal of medicinal chemistry.

Inhibitors of type I MetAPs containing pyridine-2-carboxylic acid thiazol-2-ylamide. Part 1: SAR studies on the determination of the key scaffold.

F. Nan, Q. Ye, Qun-Li Luo, 2005, Bioorganic & medicinal chemistry letters.

Identification of potent type I MetAPs inhibitors by simple bioisosteric replacement. Part 2: SAR studies of 5-heteroalkyl substituted TCAT derivatives.

F. Nan, Q. Ye, L. Chen, 2005, Bioorganic & medicinal chemistry letters.

Probing Ligand-Specific Histamine H1- and H2-Receptor Conformations with NG-Acylated Imidazolylpropylguanidines

R. Seifert, A. Buschauer, S. Xie, 2006, Journal of Pharmacology and Experimental Therapeutics.

Synthesis and pharmacological characterization of novel fluorescent histamine H2-receptor ligands derived from aminopotentidine.

R. Seifert, A. Buschauer, S. Xie, 2006, Bioorganic & medicinal chemistry letters.

Effects of Impromidine‐ and Arpromidine‐Derived Guanidines on Recombinant Human and Guinea Pig Histamine H1 and H2 Receptors

R. Seifert, A. Buschauer, S. Xie, 2007, Archiv der Pharmazie.

Design and synthesis of chromogenic thiopeptolide substrates as MetAPs active site probes.

F. Nan, Q. Ye, L. Chen, 2004, Bioorganic & medicinal chemistry.

Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop adaptability in selective inhibition of bacterial enzymes

F. Nan, S. Xie, Q. Ye, 2007 .

Structural analysis of inhibition of Mycobacterium tuberculosis methionine aminopeptidase by bengamide derivatives.

Q. Ye, Xiu-Hua Yuan, Jing-Ping Lu, 2012, European journal of medicinal chemistry.

A cell-based assay that targets methionine aminopeptidase in a physiologically relevant environment.

S. Chai, Q. Ye, 2010, Bioorganic & medicinal chemistry letters.