J. Pesquero

J. Stewart, J. Scharfstein, Daniele Andrade, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The generation and utilization of a cancer-oriented representation of the human transcriptome by using expressed sequence tags

Marcio Luis Acencio, C. V. Jongeneel, John Quackenbush, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Vascular endothelial growth factor as a biomarker for endostatin gene therapy.

R. Chammas, J. Pesquero, N. Schor, 2013, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Functional rescue of a defective angiotensin II AT1 receptor mutant by the Mas protooncogene

J. Schanstra, C. Costa-Neto, J. Pesquero, 2007, Regulatory Peptides.

Fate of bradykinin on the rat liver when administered by the venous or arterial route

M. Juliano, J. Pesquero, L. Gioli-Pereira, 2005, Journal of gastroenterology and hepatology.

Expression of functional recombinant human factor IX in milk of mice

M. Brigido, J. Pesquero, E. Rech, 2008, Biotechnology Letters.

Elastase-2, a Tissue Alternative Pathway for Angiotensin II Generation, Plays a Role in Circulatory Sympathovagal Balance in Mice

J. Pesquero, M. Bader, R. Lataro, 2017, Front. Physiol..

4 Animal models in the kinin fi eld

J. Pesquero, L. Turaça, V. Sales, 2011 .

Targeted Next-Generation Sequencing in Brazilian Children With Nephrotic Syndrome Submitted to Renal Transplant

J. Pesquero, P. K. Koch Nogueira, M. C. Franco, 2017, Transplantation.

Genetic Profile of Inborn Errors of Immunity Using Whole Exome Sequencing in Individuals With BCG Localized Adverse Events

J. Pesquero, L. Weckx, S. Monteiro, 2021 .

The B1-agonist [des-Arg10]-kallidin activates transcription factor NF-kappaB and induces homologous upregulation of the bradykinin B1-receptor in cultured human lung fibroblasts.

J. Schanstra, C. Hirtz, J. Pesquero, 1998, The Journal of clinical investigation.

Increased bone loss and amount of osteoclasts in kinin B1 receptor knockout mice.

M. Mori, J. Pesquero, I. Longo-Maugéri, 2013, Journal of clinical periodontology.

B-1 lymphocytes differentiate into functional osteoclast-like cells.

J. Pesquero, J. D. Lopes, M. Mariano, 2012, Immunobiology.

Blockade of Bradykinin Receptor B1 but Not Bradykinin Receptor B2 Provides Protection From Cerebral Infarction and Brain Edema

T. Renné, G. Stoll, M. Brede, 2009, Stroke.

ACE Protein Expression in Transfected CHO Cells

M. Mori, D. Casarini, J. Pesquero, 2008 .

Deletion of bradykinin B1 receptor reduces renal fibrosis.

N. Câmara, J. Pesquero, M. Cenedeze, 2009, International immunopharmacology.

Hereditary Angioedema with Normal C1 Inhibitor and F12 Mutations in 42 Brazilian Families.

S. Cichon, J. Pesquero, L. Arruda, 2017, The journal of allergy and clinical immunology. In practice.

Intramucosally with IL-17-Producing T Cells in Mice Infected-and γ Fimbriae-Specific IFN-Released by Gingipain Induce Kinin Danger Signals Proteolytically

J. Scharfstein, J. Potempa, K. Nguyen, 2009 .

Carbamazepine inhibits angiotensin I-converting enzyme, linking it to the pathogenesis of temporal lobe epilepsy

E. Cavalheiro, G. Gallo, M. Würtele, 2012, Translational Psychiatry.

New mutations in the GLA gene in Brazilian families with Fabry disease

C. Lourenço, W. Marques, J. Pesquero, 2012, Journal of Human Genetics.

Cellular Changes Induced by Kinin B1 Receptor Deletion: Study of Endothelial Nitric Oxide Metabolism

J. Pesquero, R. Landgraf, R. Loiola, 2015, International Journal of Peptide Research and Therapeutics.

Leptin deficiency leads to the regulation of kinin receptors expression in mice

M. Mori, J. Pesquero, K. Abe, 2007, Regulatory Peptides.

11β-hydroxysteroid dehydrogenase type 1 is not over expressed in cushing’s syndrome adipose depots

J. Pesquero, C. Kater, D. Antunes, 2014 .

Interactions between angiotensin-(1-7), kinins, and angiotensin II in kidney and blood vessels.

J. Pesquero, A. C. Simões e Silva, K. T. Passaglio, 2001, Hypertension.

High expression of human carboxypeptidase M in Pichia pastoris: purification and partial characterization.

J. Pesquero, J. Chagas, J. L. Pesquero, 2006, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Purification and partial characterization of two phospholipases A2 from Bothrops leucurus (white-tailed-jararaca) snake venom.

C. Bincoletto, J. Pesquero, J. Chagas, 2007, Biochimie.

miRNA Profile in Hippocampus, Prefrontal Cortex and Sperm of Spontaneously Hypertensive Rats (SHR), a Model for Schizophrenia

J. Pesquero, I. Cantão, T. Stumpp, 2020, Journal of Genetic Engineering and Biotechnology Research.

Influence of bradykinin B1 and B2 receptors in the immune response triggered by renal ischemia-reperfusion injury.

N. Câmara, J. Pesquero, M. Cenedeze, 2006, International immunopharmacology.

Cooperative Activation of TLR 2 and Bradykinin B 2 Receptor Is Required for Induction of Type 1 Immunity in a Mouse Model of Subcutaneous Infection by Trypanosoma cruzi 1

I. C. Almeida, J. Scharfstein, R. Gazzinelli, 2006 .

Angiotensin (5–8) modulates nociception at the rat periaqueductal gray via the NO–sGC pathway and an endogenous opioid

F. Murad, M. Juliano, J. Pesquero, 2013, Neuroscience.

Role of the Cys18–Cys274 disulfide bond and of the third extracellular loop in the constitutive activation and internalization of angiotensin II type 1 receptor

C. Costa-Neto, J. Pesquero, A. Paiva, 2006, Regulatory Peptides.

Lack of kinin B1 receptor potentiates leptin action in the liver

E. Ropelle, M. A. Saad, M. Saad, 2013, Journal of Molecular Medicine.

Angiotensin-Converting Enzyme Inhibitor Protects Against Cisplatin Nephrotoxicity by Modulating Kinin B1 Receptor Expression and Aminopeptidase P Activity in Mice

N. Câmara, F. Wasinski, J. Pesquero, 2020, Frontiers in Molecular Biosciences.

Association of Daily Dietary Intake and Inflammation Induced by Marathon Race

J. Pesquero, Rodrigo A Oliveira, A. Sierra, 2019, Mediators of inflammation.

Tonin in rat heart with experimental hypertrophy.

J. Pesquero, M. Bader, José Antônio Silva, 2003, American journal of physiology. Heart and circulatory physiology.

Bradykinin B 1 Receptor Expression Induced by Tissue Damage in the Rat Portal Vein A Critical Role for Mitogen-Activated Protein Kinase and Nuclear Factor- (cid:1) B Signaling Pathways

E. Fernandes, J. Calixto, M. Campos, 2004 .

Increased kallikrein expression protects against cardiac ischemia

Y. Pinto, W. H. Gilst, C. Tschöpe, 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Chemotherapy-induced fatigue is associated with changes in gene expression in the peripheral blood mononuclear cell fraction of patients with locoregional breast cancer

J. Pesquero, A. del Giglio, F. Fonseca, 2018, Supportive Care in Cancer.

Kinin‐B1 and B2 receptor activity in proliferation and neural phenotype determination of mouse embryonic stem cells

H. Ulrich, A. A. Nery, M. Pillat, 2015, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

Effects of transforming growth factor‐β in the development of inflammatory pseudotumour‐like lesions in a murine model

J. Pesquero, M. Jasiulionis, J. Silva, 2006 .

Vascular Kinin B1 and B2 Receptors Determine Endothelial Dysfunction through Neuronal Nitric Oxide Synthase

V. Lemos, J. Pesquero, E. Camargo, 2017, Front. Physiol..

Expression and localization of N-domain ANG I-converting enzymes in mesangial cells in culture from spontaneously hypertensive rats.

R. Mortara, D. Casarini, J. Pesquero, 2006, American journal of physiology. Renal physiology.

Expression and localization of N-domain angiotensin I-converting enzymes (ACE) in mesangial cells in culture from spontaneously hypertensive rats (SHR).

R. Mortara, J. Pesquero, A. K. Carmona, 2005 .

SERPING1 Variants and C1-INH Biological Function: A Close Relationship With C1-INH-HAE

S. Cichon, M. López-Trascasa, J. Pesquero, 2022, Frontiers in Allergy.

Nonpeptide AVE 0991 Is an Angiotensin-(1–7) Receptor Mas Agonist in the Mouse Kidney

T. Walther, N. Alenina, R. Santos, 2004, Hypertension.

Kinin B1 receptor stimulation modulates leptin homeostasis. Evidence for an insulin-dependent mechanism.

M. Mori, J. Pesquero, R. Araújo, 2008, International immunopharmacology.

Renal expression of two rat kallikrein genes under diabetic conditions

C. Tschöpe, E. Ritz, A. Reinecke, 1997, Journal of hypertension.

Modulation of kinin B1 receptor expression by endogenous angiotensin II in hypertensive rats

Z. Fortes, R. Santos, J. Pesquero, 2006, Regulatory Peptides.

B1 and B2 kinin receptor blockade improves psoriasis‐like disease

J. Calixto, J. Pesquero, M. Otuki, 2020, British journal of pharmacology.

Role of Endothelial Kinin B1 Receptor on the Membrane Potential of Transgenic Rat Aorta.

J. Pesquero, V. Merino, V. Sales, 2022, Physiological research.

Impairment on Cardiopulmonary Function after Marathon: Role of Exhaled Nitric Oxide

R. Vieira, J. Pesquero, I. S. Genaro, 2019, Oxidative medicine and cellular longevity.

Genetically altered animal models in the kallikrein-kinin system

J. Pesquero, M. Bader, 2006, Biological chemistry.

Detrimental implication of B1 receptors in myocardial ischemia: evidence from pharmacological blockade and gene knockout mice.

J. Pesquero, M. Bader, C. Ribuot, 2002, International immunopharmacology.

A Study of a Cohort of X-Linked Myotubular Myopathy at the Clinical, Histologic, and Genetic Levels.

E. Zanoteli, U. Reed, A. Oliveira, 2016, Pediatric neurology.

Participation of transmembrane proline 82 in angiotensin II AT1 receptor signal transduction

J. Schanstra, C. Costa-Neto, J. Pesquero, 2007, Regulatory Peptides.

Higher frequency of paraoxonase gene polymorphism and cardiovascular impairment among Brazilian Fabry Disease patients.

Ana Martins, J. Pesquero, V. D’Almeida, 2012, Clinical biochemistry.

Protective actions of human tissue kallikrein gene in transgenic rat hearts.

J. Pesquero, M. Bader, J. A. Silva, 2008, International immunopharmacology.

A rare mutation in the F12 gene in a patient with ACE inhibitor-induced angioedema.

J. Pesquero, F. Serpa, C. Veronez, 2017, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Role of the kinin B1 receptor in insulin homeostasis and pancreatic islet function

M. Mori, J. Schanstra, C. Nakaie, 2006, Biological chemistry.

Different metabolic responses induced by long-term interdisciplinary therapy in obese adolescents related to ACE I/D polymorphism

S. Tufik, J. Pesquero, A. Dâmaso, 2017, Journal of the renin-angiotensin-aldosterone system : JRAAS.

Role of vascular Kinin B1 and B2 receptors in endothelial nitric oxide metabolism

C. Scavone, J. Pesquero, D. Abdalla, 2011, Peptides.

Reduced cardiac hypertrophy and altered blood pressure control in transgenic rats with the human tissue kallikrein gene

D. Ganten, R. Plehm, L. Chao, 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The role of kinin B1 and B2 receptors in the scratching behaviour induced by proteinase‐activated receptor‐2 agonists in mice

L. Juliano, J. Calixto, J. Pesquero, 2010, British journal of pharmacology.

ACTN3 R577X Polymorphism Impacts Glucose Consumption at Simulated High Altitude

D. Hipólide, J. Pesquero, R. Bottura, 2020, Prime Archives in Genetics.

Renal Ultrasound contributes to Fabry Disease Diagnosis

G. Kirsztajn, J. Pesquero, D. E. Fernandes, 2020 .

Functional and molecular evidence for heteromeric association of P2Y1 receptor with P2Y2 and P2Y4 receptors in mouse granulocytes

G. Z. Justo, J. Pesquero, E. Paredes-Gamero, 2016, BMC Pharmacology and Toxicology.

Effect of combined NPHS2 and ACTN4 variants in the onset and severity of focal segmental glomerulosclerosis

G. Kirsztajn, J. Pesquero, D. E. Fernandes, 2022, Journal of Rare Diseases Research & Treatment.

Diacylglycerol kinase epsilon nephropathy: late diagnosis and therapeutic implications

J. Pesquero, D. Wanderley, M. I. de Holanda, 2019, Clinical Kidney Journal.

Tonin expression in the rat brain and tonin-mediated central production of angiotensin II

J. Pesquero, M. Bader, J. L. Pesquero, 2002, Physiology & Behavior.

Structure of the mammalian kinin receptor gene locus.

J. Pesquero, M. Bader, D. Cabrini, 2002, International immunopharmacology.

Interplay between parasite cysteine proteases and the host kinin system modulates microvascular leakage and macrophage infection by promastigotes of the Leishmania donovani complex.

M. Mori, J. Scharfstein, P. R. Batista, 2006, Microbes and infection.

Kinin B1 and B2 receptors are overexpressed in the hippocampus of humans with temporal lobe epilepsy

Mauro Canzian, Esper Abrão Cavalheiro, João Bosco Pesquero, 2007, Hippocampus.

Modulation of B1 and B2 kinin receptors expression levels in the hippocampus of rats after audiogenic kindling and with limbic recruitment, a model of temporal lobe epilepsy.

D. Gitaí, M. L. Paço-Larson, N. Garcia-Cairasco, 2008, International immunopharmacology.

Role of kinin B1 and B2 receptors in the development of pilocarpine model of epilepsy

E. Cavalheiro, J. Pesquero, M. Bader, 2004, Brain Research.

Evidence for the participation of kinins in Freund's adjuvant-induced inflammatory and nociceptive responses in kinin B1 and B2 receptor knockout mice

J. Calixto, M. Campos, J. Pesquero, 2001, Neuropharmacology.

Role of Bradykinin B2 and B1 Receptors in the Local, Remote, and Systemic Inflammatory Responses That Follow Intestinal Ischemia and Reperfusion Injury1

Michael Bader, João Bosco Pesquero, Mauro M Teixeira, 2004, The Journal of Immunology.

RNA and DNA aptamers in cytomics analysis

Henning Ulrich, João Bosco Pesquero, H. Ulrich, 2004, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

Kinin Danger Signals Proteolytically Released by Gingipain Induce Fimbriae-Specific IFN-γ- and IL-17-Producing T Cells in Mice Infected Intramucosally with Porphyromonas gingivalis1

J. Scharfstein, J. Potempa, K. Nguyen, 2009, The Journal of Immunology.

Increased susceptibility to endotoxic shock in transgenic rats with endothelial overexpression of kinin B1 receptors

J. Pesquero, Ovidiu Constantin Baltatu, M. Bader, 2008, Journal of Molecular Medicine.

Hypoalgesia and altered inflammatory responses in mice lacking kinin B1 receptors.

T. Walther, C. Stucky, G. Lewin, 2000, Proceedings of the National Academy of Sciences of the United States of America.

The use of kinin B1 and B2 receptor knockout mice and selective antagonists to characterize the nociceptive responses caused by kinins at the spinal level

J. Calixto, M. Campos, J. Pesquero, 2002, Neuropharmacology.

An improved method to distinguish Entamoeba histolytica and Entamoeba dispar

J. Pesquero, M. A. Gomes, J. L. Pesquero, 1999, Parasitology.

A cyclopalladated complex interacts with mitochondrial membrane thiol-groups and induces the apoptotic intrinsic pathway in murine and cisplatin-resistant human tumor cells

S. Smaili, L. Travassos, R. M. Martins, 2011, BMC Cancer.

Functional and molecular evidence for heteromeric association of P2Y1 receptor with P2Y2 and P2Y4 receptors in mouse granulocytes

G. Z. Justo, J. Pesquero, E. Paredes-Gamero, 2016, BMC Pharmacology and Toxicology.

Activation of P2Y1 receptor triggers two calcium signaling pathways in bone marrow erythroblasts.

J. Pesquero, E. Paredes-Gamero, J. P. França, 2006, European journal of pharmacology.

Novel GLA Mutation Promotes Intron Inclusion Leading to Fabry Disease

J. Pesquero, Patrícia Varela, Myrtes Martins Caldas, 2019, Front. Genet..

Correlation between GLA variants and alpha-Galactosidase A profile in dried blood spot: an observational study in Brazilian patients

J. Pesquero, V. D’Almeida, L. Turaça, 2020, Orphanet journal of rare diseases.

The Challenge of Diagnosis and Indication for Treatment in Fabry Disease

V. G. Pereira, J. Pesquero, V. D’Almeida, 2017 .

Angiotensin II AT1 receptor mutants expressed in CHO cells caused morphological change and inhibition of cell growth

C. Costa-Neto, J. Pesquero, A. Paiva, 2005, Regulatory Peptides.

A transcript finishing initiative for closing gaps in the human transcriptome.

Christine Hackel, Mari Cleide Sogayar, Silvana Giuliatti, 2004, Genome research.

Altered Glucose Homeostasis and Hepatic Function in Obese Mice Deficient for Both Kinin Receptor Genes

Michael Bader, M. Mori, A. Boschero, 2012, PloS one.

Kinin B1 Receptor Deficiency Leads to Leptin Hypersensitivity and Resistance to Obesity

M. Mori, J. Schanstra, P. Even, 2008, Diabetes.

Altered Neutrophil Homeostasis in Kinin B1 Receptor-Deficient Mice

I. Fichtner, J. Pesquero, R. Kettritz, 2001, Biological chemistry.

The contribution of 700,000 ORF sequence tags to the definition of the human transcriptome

Emmanuel Dias-Neto, Sergio Verjovski-Almeida, Christine Hackel, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Activation of the Kinin B1 Receptor by Its Agonist Reduces Melanoma Metastasis by Playing a Dual Effect on Tumor Cells and Host Immune Response

S. Ramos, C. Costa-Neto, J. Pesquero, 2019, Front. Pharmacol..

Kinin-B2 Receptor Activity in Skeletal Muscle Regeneration and Myoblast Differentiation

J. Krieger, H. Ulrich, J. Alves, 2018, Stem Cell Reviews and Reports.

Molecular and pharmacological evidence for modulation of kinin B1 receptor expression by endogenous glucocorticoids hormones in rats

J. Calixto, M. Campos, J. Pesquero, 2001, British journal of pharmacology.

Deregulation of Ikaros expression in B‐1 cells: New insights in the malignant transformation to chronic lymphocytic leukemia

N. Moretti, J. Pesquero, S. Schenkman, 2019, Journal of leukocyte biology.

Kinin-B2 Receptor Activity Determines the Differentiation Fate of Neural Stem Cells*

A. Muotri, H. Ulrich, C. Trujillo, 2012, The Journal of Biological Chemistry.

Low level laser therapy modulates kinin receptors mRNA expression in the subplantar muscle of rat paw subjected to carrageenan-induced inflammation.

R. Albertini, J. Pesquero, M. Costa, 2008, International immunopharmacology.

Primary Role for Kinin B1 and B2 Receptors in Glioma Proliferation

M. Campos, J. Pesquero, F. Morrone, 2017, Molecular Neurobiology.

Host kinin B1 receptor plays a protective role against melanoma progression

S. Ramos, C. Costa-Neto, J. Pesquero, 2016, Scientific Reports.

Circulating RNA Transcriptome of Pregnant Women with TSH Just Above the Trimester-Specific Reference and its Correlation with the Hypertensive Phenotype

J. Pesquero, C. Camacho, H. Dellê, 2020, Scientific Reports.

Transgenic Animals: Principles, Methods and Applications

J. Pesquero, S. M. Oliveira, H. A. Baptista, 2016 .

Brazilian Guidelines for Hereditary Angioedema Management - 2017 Update Part 1: Definition, Classification and Diagnosis

D. Solé, N. Rosário, J. Pesquero, 2018, Clinics.

C. Nakaie, C. Costa-Neto, J. Pesquero, 2006, Peptides.

Systemic site of action for pressor effect of angiotensin II injected into the fourth cerebral ventricle of rats?

J. Pesquero, A. Paiva, C. J. Lindsey, 2002, Canadian journal of physiology and pharmacology.

Increased blood pressure and water intake in transgenic mice expressing rat tonin in the brain

V. Gross, N. Alenina, A. Ferreira, 2010, Biological chemistry.

Disruption of the kinin B1 receptor gene affects potentiating effect of captopril on BK-induced contraction in mice stomach fundus

J. Pesquero, A. Paiva, S. Shimuta, 2006, Peptides.

Thimet Oligopeptidase (EC 3.4.24.15) Key Functions Suggested by Knockout Mice Phenotype Characterization

S. Tufik, F. Cunha, J. Pesquero, 2019, Biomolecules.

Hereditary Angioedema-Associated Acute Pancreatitis in C1-Inhibitor Deficient and Normal C1-Inhibitor Patients: Case Reports and Literature Review

J. Pesquero, R. Campos, A. Grumach, 2019, Front. Med..

Genetic analysis of hereditary angioedema in a Brazilian family by targeted next generation sequencing

L. Velloso, J. Pesquero, E. Mansour, 2016, Biological chemistry.

Gene mapping strategy for Alu elements rearrangements: Detection of new large deletions in the SERPING1 gene causing hereditary angioedema in Brazilian families.

J. Pesquero, L. Arruda, A. Grumach, 2019, Gene.

International consensus on the use of genetics in the management of hereditary angioedema.

S. Cichon, M. Margaglione, Á. Szilágyi, 2020, The journal of allergy and clinical immunology. In practice.

New mutations in SERPING1 gene of Brazilian patients with hereditary angioedema

J. Pesquero, E. Mansour, M. Buzolin, 2016, Biological chemistry.

Increase in kinins on post-exercise hypotension in normotensive and hypertensive volunteers

M. Moraes, D. Casarini, J. Pesquero, 2007, Biological chemistry.

Leucurogin and melanoma therapy

T. Paschoalin, L. Travassos, J. Pesquero, 2019, Toxicon : official journal of the International Society on Toxinology.

Endothelial B2‐receptor overexpression as an alternative animal model for hereditary angioedema

J. Pesquero, M. Bader, E. Popova, 2019, Allergy.

Reduced Nerve Injury-Induced Neuropathic Pain in Kinin B1 Receptor Knock-Out Mice

M. Mori, J. Calixto, J. Pesquero, 2005, The Journal of Neuroscience.

Blockade of the kinin B1 receptor ameloriates glomerulonephritis.

D. Salant, J. Schanstra, P. Heeringa, 2010, Journal of the American Society of Nephrology : JASN.

Unnecessary Abdominal Surgeries in Attacks of Hereditary Angioedema with Normal C1 Inhibitor

J. Pesquero, L. Arruda, P. Giavina-Bianchi, 2021, Clinical Reviews in Allergy & Immunology.

The Challenges in the Follow-Up and Treatment of Brazilian Children with Hereditary Angioedema

F. Minafra, J. Pesquero, L. Arruda, 2021, International Archives of Allergy and Immunology.

Short-term Prophylaxis for Delivery in Pregnant Women with Hereditary Angioedema with Normal C1-Inhibitor

J. Pesquero, N. R. Rosário Filho, Lilian Pereira Ferrari, 2020, Revista Brasileira de Ginecologia e Obstetricia / RBGO - Gynecology and Obstetrics.

Abstracts from the 10th C1-inhibitor deficiency workshop

William H. Yang, A. Szilágyi, M. Margaglione, 2017, Allergy, Asthma & Clinical Immunology.

Genetic Variation of Kallikrein-Kinin System and Related Genes in Patients With Hereditary Angioedema

J. Pesquero, E. Mansour, M. Guilarte, 2019, Front. Med..

Novel Complex ABCA4 Alleles in Brazilian Patients With Stargardt Disease: Genotype-Phenotype Correlation.

J. Pesquero, J. Chiang, J. Sallum, 2017, Investigative ophthalmology & visual science.

Homozygosity for a factor XII mutation in one female and one male patient with hereditary angio‐oedema

S. Cichon, M. Nöthen, J. Pesquero, 2016, Allergy.

Pregnancy in Patients With Hereditary Angioedema and Normal C1 Inhibitor

J. Pesquero, N. R. Rosário Filho, L. Arruda, 2022, Frontiers in Allergy.

First report of a FXII gene mutation in a Brazilian family with hereditary angio‐oedema with normal C1 inhibitor

S. Cichon, M. Nöthen, T. Renné, 2015, The British journal of dermatology.

Use of pdC1-INH concentrate for long-term prophylaxis during pregnancy in hereditary angioedema with normal C1-INH.

J. Pesquero, P. Giavina-Bianchi, M. V. Aun, 2018, The journal of allergy and clinical immunology. In practice.

SERPING1 mutation in a rare hereditary angioedema with skin blisters.

J. Pesquero, F. Serpa, C. Veronez, 2019, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Homologous and heterologous induction of the human bradykinin B1-receptor and B1-receptor localisation along the rat nephron.

J. Schanstra, J. Pesquero, J. Bascands, 1999, Immunopharmacology.

Structure and expression of two kininogen genes in mice

P. Meneton, J. Pesquero, M. Bader, 2004, Biological chemistry.

International Consensus on the Use of Genetics in the Management of Hereditary Angioedema

S. Cichon, M. Margaglione, H. Farkas, 2020 .

Predisposition to atherosclerosis and aortic aneurysms in mice deficient in kinin B1 receptor and apolipoprotein E

M. Mori, J. Pesquero, M. Bader, 2009, Journal of Molecular Medicine.

Necklace fibers as histopathological marker in a patient with severe form of X-linked myotubular myopathy

E. Zanoteli, U. Reed, M. Vainzof, 2012, Neuromuscular Disorders.

Variants in the ABCA4 gene in a Brazilian population with Stargardt disease

J. Pesquero, J. Chiang, J. Sallum, 2018, Molecular vision.

PROM1 gene variations in Brazilian patients with macular dystrophy

J. Pesquero, M. V. Salles, R. Martin, 2017, Ophthalmic genetics.

Cathepsin L in COVID-19: From Pharmacological Evidences to Genetics

J. Pesquero, G. Mastroianni-Kirsztajn, D. E. Fernandes, 2020, Frontiers in Cellular and Infection Microbiology.

3rd GUIDELINE FOR PERIOPERATIVE CARDIOVASCULAR EVALUATION OF THE BRAZILIAN SOCIETY OF CARDIOLOGY

A. Pereira, B. Caramelli, E. Moriguchi, 2017, Arquivos brasileiros de cardiologia.

Effect of 12 weeks of resistance exercise on post-exercise hypotension in stage 1 hypertensive individuals

M. Würtele, F. Wasinski, H. Simões, 2012, Journal of Human Hypertension.

Urine proteomics as a non-invasive approach to monitor exertional rhabdomyolysis during military training

J. Moreira, J. Pesquero, G. Palmisano, 2021, bioRxiv.

A New Mutation in IDS Gene Causing Hunter Syndrome: A Case Report

J. Pesquero, V. D’Almeida, M. Curiati, 2020, Frontiers in Genetics.

S-phase reduction in T47D human breast cancer epithelial cells induced by an S100P antisense-retroviral construct.

J. Russo, J. Pesquero, I. D. Silva, 2007, Oncology reports.

Risk factors and future directions for preventing and diagnosing exertional rhabdomyolysis

E. Zanoteli, Giscard Lima, J. Moreira, 2021, Neuromuscular Disorders.

Transcriptional regulation of the rat bradykinin B2 receptor gene: identification of a silencer element.

Michael Bader, J. Schanstra, J. Estève, 2002, Molecular pharmacology.

Molecular structure and expression of rat bradykinin B2 receptor gene. Evidence for alternative splicing.

D. Ganten, J. Pesquero, M. Bader, 1994, The Journal of biological chemistry.

Mismatch Repair Genes and EPCAM germline mutations in patients with gastric or colorectal cancer with suspected of Lynch syndrome.

J. Pesquero, N. Forones, C. Pimenta, 2018 .

Brabykinin B1 Receptor Antagonism Is Beneficial in Renal Ischemia-Reperfusion Injury

N. Câmara, J. Pesquero, M. Cenedeze, 2008, PloS one.

Kinin‐B2 receptor expression and activity during differentiation of embryonic rat neurospheres

H. Ulrich, C. Trujillo, J. Alves, 2008, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

CASE SERIES OF PATIENTS UNDER BIWEEKLY TREATMENT WITH LARONIDASE: A REPORT OF A SINGLE CENTER EXPERIENCE

V. G. Pereira, J. Pesquero, H. Nader, 2019, Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo.

Deletion of Kinin B2 Receptor Alters Muscle Metabolism and Exercise Performance

R. Curi, S. Hirabara, M. Ormanji, 2015, PloS one.

Kinin B1 receptors facilitate the development of temporal lobe epilepsy in mice.

E. Cavalheiro, J. Pesquero, M. Naffah-Mazzacoratti, 2008, International immunopharmacology.

Synonymous Variant in the CHM Gene Causes Aberrant Splicing in Choroideremia

J. Pesquero, J. Sallum, M. V. Salles, 2020, Investigative ophthalmology & visual science.

Molecular Structure and Alternative Splicing of the Human Carboxypeptidase M Gene

J. Pesquero, M. Bader, A. Paiva, 2002, Biological chemistry.

Angiotensin Converting Enzyme Regulates Cell Proliferation and Migration

V. Freire, M. Leite, A. M. de Paula, 2016, PloS one.

Association between polymorphism in gene related to the dopamine circuit and motivations for drinking in patients with alcohol use disorder

J. Pesquero, D. Mazzotti, R. Conte, 2020, Psychiatry Research.

Chronic Overexpression of Bradykinin in Kidney Causes Polyuria and Cardiac Hypertrophy

R. Plehm, N. Alenina, S. Bachmann, 2018, Front. Med..

Effect of the bradykinin 1 receptor antagonist SSR240612 after oral administration in Mycobacterium tuberculosis-infected mice.

A. Villela, V. Rodrigues-Junior, L. A. Basso, 2018, Tuberculosis.

GCN2 activation and eIF2alpha phosphorylation in the maturation of mouse oocytes.

B. A. Castilho, J. Pesquero, M. Roffé, 2009, Biochemical and biophysical research communications.

Angiostatic activity of human plasminogen fragments is highly dependent on glycosylation

L. Barcelos, V. Cardoso, J. Pesquero, 2010, Cancer science.

Mutations analysis of the HSP90 gene in infertile men with idiopathic azoospermia and severe oligozoospermia

L. Yamamoto, J. Pesquero, S. Lima, 2002 .

The relevance of kinin B1 receptor upregulation in a mouse model of colitis

G. F. Passos, J. Calixto, J. Pesquero, 2008, British journal of pharmacology.

Exercise Induced-Cytokines Response in Marathon Runners: Role of ACE I/D and BDKRB2 +9/-9 Polymorphisms

J. Pesquero, R. L. Neves, H. P. de Souza, 2022, Frontiers in Physiology.

Chronic Conventional Resistance Exercise Reduces Blood Pressure in Stage 1 Hypertensive Men

M. Würtele, M. Moraes, T. Rosa, 2012, Journal of strength and conditioning research.

Kallikrein kinin system activation in post-exercise hypotension in water running of hypertensive volunteers.

M. Moraes, D. Casarini, J. Pesquero, 2008, International immunopharmacology.

The non-peptide kinin receptor antagonists FR 173657 and SSR 240612: Preclinical evidence for the treatment of skin inflammation

J. Pesquero, M. Otuki, M. Bader, 2009, Regulatory Peptides.

A new mutation in PYGM causing McArdle disease in a Brazilian patient

E. Zanoteli, J. Pesquero, C. P. Gomes, 2019, Acta Neurologica Belgica.

Impact of Prenatal Alcohol Exposure on the Development and Myocardium of Adult Mice: Morphometric Changes, Transcriptional Modulation of Genes Related to Cardiac Dysfunction, and Antioxidant Cardioprotection

J. Pesquero, S. Zamuner, C. P. Gomes, 2023, Antioxidants.

Kinin B1 receptor deficiency attenuates cisplatin-induced acute kidney injury by modulating immune cell migration

N. Câmara, F. Wasinski, J. Pesquero, 2014, Journal of Molecular Medicine.

RNA and DNA Aptamers in Cytomics Analysis

H. Ulrich, A. H. Martins, J. Pesquero, 2005, Current protocols in cytometry.

Balance between the two kinin receptors in the progression of experimental focal and segmental glomerulosclerosis in mice

N. Câmara, Ê. J. Bassi, I. Moura, 2014, Disease Models & Mechanisms.

Genetic differences between two Leishmania major-like strains revealed by suppression subtractive hybridization.

J. Pesquero, R. Soares, M. N. Melo, 2015, Molecular and biochemical parasitology.

Long term treatment with ACE inhibitor enalapril decreases body weight gain and increases life span in rats.

J. Pesquero, V. D’Almeida, K. de Picoli Souza, 2009, Biochemical pharmacology.

Isoleucine and atopic dermatitis

D. Solé, C. Aranda, M. Mallozi, 2017, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

Endostatin gene therapy stimulates upregulation of ICAM-1 and VCAM-1 in a metastatic renal cell carcinoma model

R. Chammas, J. Pesquero, J. Peron, 2012, Cancer Gene Therapy.

Kinin B1 Receptor in Adipocytes Regulates Glucose Tolerance and Predisposition to Obesity

M. Mori, N. Alenina, D. Guadagnini, 2012, PloS one.

Altered reactivity of gastric fundus smooth muscle in the mouse with targeted disruption of the kinin B1 receptor gene

C. Scavone, J. Pesquero, M. Carvalho, 2009, Peptides.

Novel GAA mutations in patients with Pompe disease.

J. Pesquero, V. D’Almeida, L. Turaça, 2015, Gene.

The B 1-agonist [ des-Arg 10 ]-kallidin Activates Transcription Factor NFk B and Induces Homologous Upregulation of the Bradykinin B 1 – receptor in Cultured Human Lung Fibroblasts

J. Schanstra, C. Hirtz, J. Pesquero, 1998 .

Gene and cell therapy for muscle regeneration

S. Ingham, R. Stilhano, J. Huard, 2015, Current Reviews in Musculoskeletal Medicine.

A Novel Inflammatory Pathway Involved in Leukocyte Recruitment: Role for the Kinin B1 Receptor and the Chemokine CXCL51

A. Ahluwalia, M. Perretti, J. Pesquero, 2007, The Journal of Immunology.

Receptor and the Chemokine CXCL 51 Leukocyte Recruitment : Role for the Kinin B A Novel Inflammatory Pathway Involved in Amrita

A. Ahluwalia, M. Perretti, J. Pesquero, 2007 .

Molecular cloning and functional characterization of a mouse bradykinin B1 receptor gene.

D. Ganten, A. Roscher, J. Pesquero, 1996, Biochemical and biophysical research communications.

Proteomic Analysis Reveals Alterations in the Renal Kallikrein Pathway during Hypoxia-Induced Hypertension*

Jian Cai, W. Pierce, J. Klein, 2002, The Journal of Biological Chemistry.

Autonomic control in rats with overactivity of tissue renin–angiotensin or kallikrein–kinin system

R. Santos, E. Krieger, J. Pesquero, 2005, Regulatory Peptides.

The synthesis and distribution of the kinin B1 and B2 receptors are modified in the hippocampus of rats submitted to pilocarpine model of epilepsy

E. Cavalheiro, J. Pesquero, J. Bascands, 2004, Brain Research.

Molecular biology of the kallikrein-kinin system: from structure to function.

J. Pesquero, M. Bader, 1998, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Effects of FGF-2 and EGF removal on the differentiation of mouse neural precursor cells.

M. Calcagnotto, T. T. Schwindt, L. Mello, 2009, Anais da Academia Brasileira de Ciencias.

Kinin B1 receptor gene ablation affects hypothalamic CART productionb

L. Mello, J. Pesquero, J. Bittencourt, 2013, Biological chemistry.

Correction: Bradykinin B1 Receptor Antagonism Is Beneficial in Renal Ischemia-Reperfusion Injury

N. Câmara, J. Pesquero, M. Cenedeze, 2008, PLoS ONE.

Absence of diabetic hyperalgesia in bradykinin B1 receptor-knockout mice

J. Pesquero, M. Bader, P. Sirois, 2005, Regulatory Peptides.

Essential role of TM V and VI for binding the C-terminal sequences of Des-Arg-kinins.

C. Costa-Neto, J. Pesquero, M. Bader, 2008, International immunopharmacology.

Genetic Ablation and Pharmacological Blockade of Bradykinin B1 Receptor Unveiled a Detrimental Role for the Kinin System in Chagas Disease Cardiomyopathy

J. Scharfstein, Daniele Andrade, J. Pesquero, 2023, Journal of clinical medicine.

Running Title: Kinin receptors in glomerulosclerosis.

Ê. J. Bassi, I. Moura, R. Monteiro, 2014 .

Cellular Changes Induced by Kinin B1 Receptor Deletion: Study of Endothelial Nitric Oxide Metabolism

J. Pesquero, R. Landgraf, R. Loiola, 2015, International Journal of Peptide Research and Therapeutics.

Functional expression of kinin B1 and B2 receptors in mouse abdominal aorta.

J. Pesquero, A. Paiva, S. Shimuta, 2007, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Predictors of performance in Amateur Olympic distance triathlon: Predictors in amateur triathlon.

P. Puccinelli, C. D. de Lira, R. Vancini, 2020, Physiology and Behavior.

Delayed blockade of the kinin B1 receptor reduces renal inflammation and fibrosis in obstructive nephropathy

J. Schanstra, A. Ahluwalia, J. Pesquero, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Transcriptional regulatory elements in the rat bradykinin B2 receptor gene.

D. Ganten, J. Pesquero, M. Bader, 1996, Immunopharmacology.

Kinin B1 Receptor Acts in Adipose Tissue to Control Fat Distribution in a Cell-Nonautonomous Manner

M. Mori, N. Câmara, J. Pesquero, 2019, Diabetes.

Lack of kinin B1 receptor potentiates leptin action in the liver

E. Ropelle, M. A. Saad, L. Oyama, 2013, Journal of Molecular Medicine.

Title: Role of endothelial kinin B 1 receptor on the membrane potential of transgenic rat aorta

J. Pesquero, V. Merino, V. Sales, 2022 .

The role of kinin B1 and B2 receptors in the persistent pain induced by experimental autoimmune encephalomyelitis (EAE) in mice: Evidence for the involvement of astrocytes

J. Calixto, J. Pesquero, A. Bento, 2013, Neurobiology of Disease.

Cardiac morphofunctional characteristics of transgenic rats with overexpression of the bradykinin B1 receptor in the endothelium.

D. Bocalini, J. Pesquero, L. D. dos Santos, 2017, Physiological research.

Multiple sclerosis (PP-038)

D. Arnold, F. Najafi, A. Bar-Or, 2010 .

Functional assessment of angiotensin II and bradykinin analogues containing the paramagnetic amino acid TOAC.

C. Nakaie, J. Pesquero, L. Malavolta, 2008, International immunopharmacology.

Genetic variation, inflammatory and muscle injury response in rugby players to different positions in the field

J. Pesquero, R. Gorjão, M. Benetti, 2020 .

Investigation of the cardiomyocyte dysfunction in bradykinin type 2 receptor knockout mice.

S. Guatimosim, A. Natali, J. Pesquero, 2010, Life sciences.

Characterization of the renal renin-angiotensin system in transgenic mice that express rat tonin

M. Irigoyen, D. Casarini, J. Pesquero, 2015, Journal of the renin-angiotensin-aldosterone system : JRAAS.

The role of kinin B1 receptor and the effect of angiotensin I-converting enzyme inhibition on acute gout attacks in rodents

J. McDougall, J. Pesquero, M. Bader, 2014, Annals of the rheumatic diseases.

The role of kinin B1 receptors in the nociception produced by peripheral protein kinase C activation in mice

M. Mori, J. Calixto, J. Pesquero, 2008, Neuropharmacology.

Participation of kinin receptors on memory impairment after chronic infusion of human amyloid-β 1-40 peptide in mice

J. Pesquero, H. Buck, T. Viel, 2010, Neuropeptides.

Role of kinin B1 and B2 receptors in memory consolidation during the aging process of mice

J. Pesquero, H. Buck, T. Viel, 2010, Neuropeptides.

Genetic deletion or antagonism of kinin B1 and B2 receptors improves cognitive deficits in a mouse model of Alzheimer's disease

R. Prediger, G. F. Passos, J. Calixto, 2008, Neuroscience.

Can the elite slalom kayaker’s performance be correlated with anthropometric, nutritional, genetic, psychological as sleep traits?

J. Pesquero, M. Milanski, A. Reginato, 2018, Motriz: Revista de Educação Física.

The Role of Kinin Receptors in Preventing Neuroinflammation and Its Clinical Severity during Experimental Autoimmune Encephalomyelitis in Mice

J. Calixto, J. Pesquero, C. Figueiredo, 2011, PloS one.

Intracellular proteolysis of kininogen by malaria parasites promotes release of active kinins

P. Rosenthal, L. Juliano, M. Juliano, 2012, Malaria Journal.

Association Between Hematological Parameters and Iron Metabolism Response After Marathon Race and ACTN3 Genotype

Giscard Lima, J. Seto, J. Pesquero, 2019, Front. Physiol..

Circulating RNA Transcriptome of Pregnant Women with TSH Just Above the Trimester-Specific Reference and its Correlation with the Hypertensive Phenotype

J. Pesquero, C. Camacho, H. Dellê, 2020, Scientific Reports.

Kinin receptors regulate skeletal muscle regeneration: differential effects for B1 and B2 receptors

J. Pesquero, M. Bader, F. Qadri, 2023, Inflammation Research.

Molecular Cloning and Functional Characterization of a Mouse Bradykinin B1 Receptor Gene: Volume220,Number 1 (1996), pages 219–225

D. Ganten, A. Roscher, J. Pesquero, 1996 .

Evidence that kinin B2 receptor expression is upregulated by endothelial overexpression of B1 receptors

C. Nakaie, J. Pesquero, M. Bader, 2013, Peptides.

Hemodynamic and metabolic effects of angiotensin II on the liver

J. Pesquero, L. Gioli-Pereira, E. L. Santos, 2005, Peptides.

Malaria infection promotes a selective expression of kinin receptors in murine liver

J. Pesquero, A. K. Carmona, N. Barros, 2019, Malaria Journal.

Leucurogin, a new recombinant disintegrin cloned from Bothrops leucurus (white-tailed-jararaca) with potent activity upon platelet aggregation and tumor growth.

J. Pesquero, J. L. Pesquero, E. Sanchez, 2011, Toxicon : official journal of the International Society on Toxinology.

Bradykinin metabolism pathway in the rat pulmonary circulation

J. Pesquero, A. Paiva, C. J. Lindsey, 1992, Journal of hypertension.

Interactions between carboxypeptidase M and kinin B1 receptor in endothelial cells

C. Nakaie, J. Pesquero, J. Chagas, 2019, Inflammation Research.

The role of N-terminal and C-terminal Arg residues from BK on interaction with kinin B2 receptor

C. Nakaie, J. Pesquero, Laerte Oliveira, 2016, Biological chemistry.

ACE2, ACE, DPPIV, PREP and CAT L enzymatic activities in COVID-19: imbalance of ACE2/ACE ratio and potential RAAS dysregulation in severe cases

G. Kirsztajn, J. Pesquero, R. L. Neves, 2023, Inflammation Research.

J. Pesquero, C. Camacho, Patrícia Varela, 2023, Archives of endocrinology and metabolism.

Kinin receptors in skin wound healing.

J. Pesquero, M. Otuki, M. Bader, 2016, Journal of dermatological science.

Kinin B1 receptor deficiency attenuates cisplatin-induced acute kidney injury by modulating immune cell migration

N. Câmara, F. Wasinski, J. Pesquero, 2013, Journal of Molecular Medicine.

The role of kinin B1 and B2 receptors in the persistent pain induced by experimental autoimmune encephalomyelitis (EAE) in mice: Evidence for the involvement of astrocytes

J. Calixto, J. Pesquero, A. Bento, 2013, Neurobiology of Disease.

A Study of a Cohort of X-Linked Myotubular Myopathy at the Clinical, Histologic, and Genetic Levels.

E. Zanoteli, U. Reed, A. Oliveira, 2016, Pediatric neurology.

Blockade of Bradykinin Receptor B1 but Not Bradykinin Receptor B2 Provides Protection From Cerebral Infarction and Brain Edema

T. Renné, G. Stoll, M. Brede, 2009, Stroke.

Nonpeptide AVE 0991 Is an Angiotensin-(1–7) Receptor Mas Agonist in the Mouse Kidney

T. Walther, N. Alenina, R. Santos, 2004, Hypertension.

High frequency of chronic lymphocytic leukemia-like low-count monoclonal B-cell lymphocytosis in Japanese descendants living in Brazil

A. Órfão, I. Criado, J. Pesquero, 2019, Haematologica.

Familial Focal Segmental Glomerulosclerosis With Late-Onset Presentation and R229Q/R291W Podocin Mutations

J. Pesquero, G. Mastroianni-Kirsztajn, D. E. Fernandes, 2020, Frontiers in Genetics.

Kinin B1 receptor deficiency promotes enhanced adipose tissue thermogenic response to β3-adrenergic stimulation.

J. Pesquero, M. Y. Icimoto, Jéssica Branquinho, 2024, Inflammation research : official journal of the European Histamine Research Society ... [et al.].

Aerobic physical training reduces severe asthma phenotype involving kinins pathway.

F. Aimbire, J. Pesquero, Renilson Moraes-Ferreira, 2024, Molecular biology reports.

The Burden of Hereditary Angioedema in a Large Family in Brazil.

J. Pesquero, A. Grumach, A. Mendes, 2024, International archives of allergy and immunology.

Homozygosity for a factor XII mutation in one female and one male patient with hereditary angio‐oedema

J. Pesquero, A. Grumach, M. Nöthen, 2016, Allergy.

Kinin B1 receptor and TLR4 interaction in inflammatory response.

J. Pesquero, J. V. R. Cruz, Carolina Batista, 2024, Inflammation research : official journal of the European Histamine Research Society ... [et al.].

Interaction of a non-peptide agonist with angiotensin II AT1 receptor mutants.

T. Schwartz, S. Hjorth, C. Costa-Neto, 2002, Canadian journal of physiology and pharmacology.