C. Davies

发表

Structural basis for phosphomannose isomerase activity in phosphoglucose isomerase from Pyrobaculum aerophilum: a subtle difference between distantly related enzymes.

P. Schönheit, T. Hansen, M. Swan, 2004, Biochemistry.

Direct binding of glyceraldehyde 3-phosphate dehydrogenase to telomeric DNA protects telomeres against chemotherapy-induced rapid degradation.

S. Ponnusamy, B. Ogretmen, J. Baatz, 2009, Journal of molecular biology.

Conformational variability of the N-terminal helix in the structure of ribosomal protein S15.

V. Ramakrishnan, W. M. Clemons, W. M. Clemons, 1998, Structure.

Structural Mechanisms of β-Lactam Antibiotic Resistance in Penicillin-Binding Proteins

C. Davies, R. Nicholas, 2012 .

Overexpression and enzymatic characterization of Neisseria gonorrhoeae penicillin-binding protein 4.

C. Davies, R. Nicholas, W. Gutheil, 2003, European journal of biochemistry.

High-Throughput Screening for Novel Inhibitors of Neisseria gonorrhoeae Penicillin-Binding Protein 2

Y. Peterson, C. Davies, R. Nicholas, 2012, PloS one.

Genetics of Chromosomally Mediated Intermediate Resistance to Ceftriaxone and Ceﬁxime in Neisseria gonorrhoeae (cid:1)

M. Unemo, M. Duncan, C. Davies, 2009 .

Crystal structures reveal catalytic and regulatory mechanisms of the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6

S. Olsen, E. Wasmuth, B. Ogretmen, 2022, Nature Communications.

CNPY2 is a Key Initiator of the PERK-CHOP Pathway of the Unfolded Protein Response

J. Diehl, Zihai Li, C. Davies, 2017, Nature Structural &Molecular Biology.

Biological Crystallography Crystallization and Preliminary X-ray Diffraction Analysis of Phosphoglucose/phosphomannose Isomerase from Pyrobaculum Aerophilum

P. Schönheit, T. Hansen, M. Swan, 2022 .

Amidase Activity of AmiC Controls Cell Separation and Stem Peptide Release and Is Enhanced by NlpD in Neisseria gonorrhoeae*

K. Fisher, S. Mobashery, H. Seifert, 2016, The Journal of Biological Chemistry.

Crystal structures of the carboxyl terminal domain of rat 10-formyltetrahydrofolate dehydrogenase: implications for the catalytic mechanism of aldehyde dehydrogenases.

Y. Tsybovsky, S. Krupenko, C. Davies, 2007, Biochemistry.

Structure of lipid tubules formed from a polymerizable lecithin.

P. Yager, C. Davies, R. Price, 1985, Biophysical journal.

Penicillin-Binding Protein 3 Is Essential for Growth of Pseudomonas aeruginosa

Yong-mei Zhang, C. Davies, Wei Chen, 2016, Antimicrobial Agents and Chemotherapy.

The 1.8 A crystal structure and active-site architecture of beta-ketoacyl-acyl carrier protein synthase III (FabH) from escherichia coli.

R. Heath, C. Rock, S. White, 2000, Structure.

Crystal structures of covalent complexes of β-lactam antibiotics with Escherichia coli penicillin-binding protein 5: toward an understanding of antibiotic specificity.

G. Nicola, R. Pratt, C. Davies, 2010, Biochemistry.

Crystal structure of Escherichia coli penicillin-binding protein 5 bound to a tripeptide boronic acid inhibitor: a role for Ser-110 in deacylation.

G. Nicola, C. Davies, R. Nicholas, 2005, Biochemistry.

Tetracyclines and bone: Unclear actions with potentially lasting effects.

C. Davies, C. M. Novince, J. Hathaway-Schrader, 2022, Bone.

The Structure of the Biofilm-controlling Response Regulator BfmR from Acinetobacter baumannii Reveals Details of Its DNA-binding Mechanism.

J. Cavanagh, B. Bobay, Richele J. Thompson, 2018, Journal of molecular biology.

The crystal structure of mouse phosphoglucose isomerase at 1.6A resolution and its complex with glucose 6-phosphate reveals the catalytic mechanism of sugar ring opening.

J. Chirgwin, H. Muirhead, S. Burns, 2004, Journal of molecular biology.

Crystal structure of CD59: implications for molecular recognition of the complement proteins C8 and C9 in the membrane-attack complex.

C. Davies, S. Tomlinson, Yuxiang Huang, 2007, Acta crystallographica. Section D, Biological crystallography.

Acyl Carrier Protein 3 Is Involved in Oxidative Stress Response in Pseudomonas aeruginosa

Yong-mei Zhang, C. Davies, Jordon D. Gruber, 2018, Front. Microbiol..

The crystal structure of ribosomal protein L14 reveals an important organizational component of the translational apparatus.

V. Ramakrishnan, S. White, C. Davies, 1996, Structure.

Molecular basis of neurological dysfunction coupled with haemolytic anaemia in human glucose-6-phosphate isomerase (GPI) deficiency

H. Muirhead, P. Laspe, M. Lakomek, 1998, Human Genetics.

Molecular Features of Cephalosporins Important for Activity against Antimicrobial-Resistant Neisseria gonorrhoeae.

Ashutosh Kumar Singh, C. Davies, R. Nicholas, 2021, ACS infectious diseases.

The crystal structure of human phosphoglucose isomerase at 1.6 A resolution: implications for catalytic mechanism, cytokine activity and haemolytic anaemia.

J. Chirgwin, H. Muirhead, C. Davies, 2001, Journal of molecular biology.

Structural evidence for specific S8-RNA and S8-protein interactions within the 30S ribosomal subunit: ribosomal protein S8 from Bacillus stearothermophilus at 1.9 A resolution.

V. Ramakrishnan, S. White, C. Davies, 1996, Structure.

Ribosomal protein L9: a structure determination by the combined use of X-ray crystallography and NMR spectroscopy.

V. Ramakrishnan, S. White, C. Davies, 1996, Journal of molecular biology.

The crystal structure of ribosomal protein S4 reveals a two‐domain molecule with an extensive RNA‐binding surface: one domain shows structural homology to the ETS DNA‐binding motif

D. Draper, V. Ramakrishnan, S. White, 1998, The EMBO journal.

Crystal structures of the lytic transglycosylase MltA from N.gonorrhoeae and E.coli: insights into interdomain movements and substrate binding.

Zhi-jie Liu, C. Davies, A. Powell, 2006, Journal of molecular biology.

Evidence for structural plasticity of heavy chain complementarity-determining region 3 in antibody-ssDNA recognition.

S. Prewitt, J. Tanner, S. Deutscher, 2005, Journal of molecular biology.

The role of the β5-α11 loop in the active-site dynamics of acylated penicillin-binding protein A from Mycobacterium tuberculosis.

C. Davies, R. Nicholas, A. Fedarovich, 2012, Journal of molecular biology.

A highly conserved interaction involving the middle residue of the SXN active-site motif is crucial for function of class B penicillin-binding proteins: mutational and computational analysis of PBP 2 from N. gonorrhoeae.

C. Davies, R. Nicholas, B. Temple, 2012, Biochemistry.

Ribosomal proteins S5 and L6: high-resolution crystal structures and roles in protein synthesis and antibiotic resistance.

B. Golden, V. Ramakrishnan, D. Bussiere, 1998, Journal of molecular biology.

Obtaining functional membrane vesicles from Leuconostoc oenos to study l-malate transport mechanisms

C. Davies, J. Cavin, R. Tourdot-Marechal, 1994, Applied Microbiology and Biotechnology.

Development and optimization of OspC chimeritope vaccinogens for Lyme disease.

C. Davies, R. Marconi, Lee D. Oliver, 2020, Vaccine.

Molecular and structural analysis of mosaic variants of penicillin-binding protein 2 conferring decreased susceptibility to expanded-spectrum cephalosporins in Neisseria gonorrhoeae: role of epistatic mutations.

Magnus Unemo, Christopher Davies, M. Unemo, 2010, Biochemistry.

Crystal structures of complexes of bacterial DD-peptidases with peptidoglycan-mimetic ligands: the substrate specificity puzzle.

E. Sauvage, P. Charlier, R. Pratt, 2008, Journal of molecular biology.

Helicase–Contrahelicase Interaction and the Mechanism of Termination of DNA Replication

D. Bussiere, D. Bastia, S. White, 1996, Cell.

pH, inhibitor, and substrate specificity studies on Escherichia coli penicillin-binding protein 5.

C. Davies, R. Nicholas, W. Gutheil, 2002, Biochimica et biophysica acta.

Crystal structure of π initiator protein–iteron complex of plasmid R6K: Implications for initiation of plasmid DNA replication

D. Bastia, C. Davies, M. K. Swan, 2006, Proceedings of the National Academy of Sciences.

Structure of the Fab fragment from a neutralizing monoclonal antibody directed against an epitope of gp41 from HIV-1.

H. Muirhead, J. Beauchamp, C. Davies, 1997, Acta crystallographica. Section D, Biological crystallography.

Structures of prokaryotic ribosomal proteins: implications for RNA binding and evolution.

B. Golden, V. Ramakrishnan, S. White, 1995, Biochemistry and cell biology = Biochimie et biologie cellulaire.

A site for CD4 binding in the beta 1 domain of the MHC class II protein HLA-DR1.

S. White, C. Davies, C. Doyle, 1998, Journal of immunology.

3-Phosphoglycerate is an allosteric activator of pyruvate kinase from the hyperthermophilic archaeon Pyrobaculum aerophilum.

P. Schönheit, U. Johnsen, C. Davies, 2013, Biochemistry.

Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme

S. Olsen, C. Davies, D. Divlianska, 2018, Nature Communications.

Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme

S. Olsen, C. Davies, D. Divlianska, 2018, Nature Communications.

High-Level Chromosomally Mediated Tetracycline Resistance in Neisseria gonorrhoeae Results from a Point Mutation in the rpsJ Gene Encoding Ribosomal Protein S10 in Combination with the mtrR and penB Resistance Determinants

C. Davies, R. Nicholas, S. Nandi, 2005, Antimicrobial Agents and Chemotherapy.

Identification of Amino Acids Conferring High-Level Resistance to Expanded-Spectrum Cephalosporins in the penA Gene from Neisseria gonorrhoeae Strain H041

Magnus Unemo, Christopher Davies, M. Unemo, 2013, Antimicrobial Agents and Chemotherapy.

The Crystal Structure of the Hydrolase Domain of 10-Formyltetrahydrofolate Dehydrogenase

A. Chumanevich, S. Krupenko, C. Davies, 2004, Journal of Biological Chemistry.

Genetics of Chromosomally Mediated Intermediate Resistance to Ceftriaxone and Cefixime in Neisseria gonorrhoeae

Magnus Unemo, Christopher Davies, M. Unemo, 2009, Antimicrobial Agents and Chemotherapy.

Recognition of the β-lactam carboxylate triggers acylation of Neisseria gonorrhoeae penicillin-binding protein 2

Ashutosh Kumar Singh, C. Davies, R. Nicholas, 2019, The Journal of Biological Chemistry.

Alanine 501 Mutations in Penicillin-Binding Protein 2 from Neisseria gonorrhoeae: Structure, Mechanism, and Effects on Cephalosporin Resistance and Biological Fitness.

M. Unemo, C. Davies, R. Nicholas, 2017, Biochemistry.

The structure of human phosphoglucose isomerase complexed with a transition-state analogue.

J. Chirgwin, H. Muirhead, C. Davies, 2003, Acta crystallographica. Section D, Biological crystallography.

Crystal structure of phosphoglucose isomerase from pig muscle and its complex with 5‐phosphoarabinonate

H. Muirhead, C. Davies, 2002, Proteins.

Crystal Structures of Penicillin-binding Protein 2 from Penicillin-susceptible and -resistant Strains of Neisseria gonorrhoeae Reveal an Unexpectedly Subtle Mechanism for Antibiotic Resistance*

Ashley M Deacon, Christopher Davies, A. Deacon, 2009, Journal of Biological Chemistry.

Reactivity of penicillin-binding proteins with peptidoglycan-mimetic beta-lactams: what's wrong with these enzymes?

P. Charlier, R. Pratt, C. Davies, 2006, Biochemistry.

Crystallographic studies on the structure and catalytic activity of pyruvate kinase from skeletal muscle.

H. Muirhead, C. Davies, D. Clayden, 1987, Biochemical Society transactions.

The activation domain of the MotA transcription factor from bacteriophage T4

S. White, C. Davies, M. Finnin, 1997, The EMBO journal.

Structure of native phosphoglucose isomerase from rabbit: conformational changes associated with catalytic function.

H. Muirhead, C. Davies, 2003, Acta crystallographica. Section D, Biological crystallography.

A computational model to monitor and predict trends in bacterial resistance.

Ali Alawieh, Zahraa Sabra, Abdul Rahman Bizri, 2015, Journal of global antimicrobial resistance.

The activation domain of the MotA transcription factor from bacteriophage T 4 usually within separate protein domains , and several types

S. White, C. Davies, M. Finnin, 2013 .

Structure of the N-terminal domain of human CEACAM1: binding target of the opacity proteins during invasion of Neisseria meningitidis and N. gonorrhoeae.

Christopher Davies, C. Davies, R. Nicholas, 2006, Acta crystallographica. Section D, Biological crystallography.

Electrons and X-rays gang up on the ribosome.

S. White, C. Davies, 2000, Structure.

Structural Effect of the Asp345a Insertion in Penicillin-Binding Protein 2 from Penicillin-Resistant Strains of Neisseria gonorrhoeae

C. Davies, R. Nicholas, J. Tomberg, 2014, Biochemistry.

c‐di‐GMP regulates activity of the PlzA RNA chaperone from the Lyme disease spirochete

B. Bowler, C. Davies, D. Drecktrah, 2023, Molecular microbiology.

Mutations in penicillin-binding protein 2 from cephalosporin-resistant Neisseria gonorrhoeae hinder ceftriaxone acylation by restricting protein dynamics

Ashutosh Kumar Singh, M. Unemo, C. Davies, 2020, The Journal of Biological Chemistry.

RIBOSOMAL PROTEIN L9

V. Ramakrishnan, S. White, C. Davies, 1997 .

Crystal structure of prokaryotic ribosomal protein L9: a bi‐lobed RNA‐binding protein.

V. Ramakrishnan, S. White, C. Davies, 1994, The EMBO journal.

New views on an old enzyme: allosteric regulation and evolution of archaeal pyruvate kinases

Giddy Landan, P. Schönheit, U. Johnsen, 2019, The FEBS journal.

High-resolution crystal structure of the Borreliella burgdorferi PlzA protein in complex with c-di-GMP: new insights into the interaction of c-di-GMP with the novel xPilZ domain

C. Davies, R. Marconi, Jerilyn R Izac, 2021, Pathogens and disease.

A large displacement of the SXN motif of Cys115-modified penicillin-binding protein 5 from Escherichia coli.

G. Nicola, C. Davies, R. Nicholas, 2005, The Biochemical journal.

Crystal Structure of a Deacylation-defective Mutant of Penicillin-binding Protein 5 at 2.3-Å Resolution*

S. White, C. Davies, R. Nicholas, 2001, The Journal of Biological Chemistry.

Mutations in PBP2 from ceftriaxone-resistant Neisseria gonorrhoeae alter the dynamics of the β3–β4 loop to favor a low-affinity drug-binding state

C. Davies, R. Nicholas, Carly A. Sciandra, 2021, The Journal of biological chemistry.

Crystal Structure of Wild-type Penicillin-binding Protein 5 from Escherichia coli

G. Nicola, C. Davies, R. Nicholas, 2003, Journal of Biological Chemistry.

Crystal structure of SUMO E1 in complex with an allosteric inhibitor

S. Olsen, C. Davies, D. Divlianska, 2018 .

Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme

S. Olsen, C. Davies, D. Divlianska, 2018, Nature Communications.

Unusual conformation of the SxN motif in the crystal structure of penicillin-binding protein A from Mycobacterium tuberculosis.

C. Davies, R. Nicholas, A. Fedarovich, 2010, Journal of molecular biology.

Mutagenesis of catalytically important residues of cupin type phosphoglucose isomerase from Archaeoglobus fulgidus

J. Grötzinger, P. Schönheit, T. Hansen, 2005, The FEBS journal.

A Novel Phosphoglucose Isomerase (PGI)/Phosphomannose Isomerase from the Crenarchaeon Pyrobaculum aerophilum Is a Member of the PGI Superfamily

P. Schönheit, T. Hansen, C. Davies, 2004, Journal of Biological Chemistry.

Structural Evidence for a Hydride Transfer Mechanism of Catalysis in Phosphoglucose Isomerase from Pyrococcus furiosus*

P. Schönheit, T. Hansen, C. Davies, 2003, Journal of Biological Chemistry.

M. Unemo, C. Davies, R. Nicholas, 2010, Biochemistry.

Discovery of a novel transcriptional regulator of sugar catabolism in archaea

Katherine R. Weber, J. Maupin-Furlow, P. Schönheit, 2023, Molecular microbiology.

Crystallization and preliminary X-ray diffraction analysis of phosphoglucose isomerase from Pyrococcus furiosus.

P. Schönheit, T. Hansen, C. Davies, 2003, Protein and peptide letters.

Identification of Amino Acids Conferring High-Level Resistance to Expanded-Spectrum Cephalosporins in the penA Gene from Neisseria gonorrhoeae Strain H041

M. Unemo, M. Ohnishi, C. Davies, 2013, Antimicrobial Agents and Chemotherapy.

Crystallization and preliminary X-ray diffraction analysis of recombinant hydrolase domain of 10-formyltetrahydrofolate dehydrogenase.

Christopher Davies, A. Chumanevich, S. Krupenko, 2002, Acta crystallographica. Section D, Biological crystallography.

The role of the β5-α11 loop in the active-site dynamics of acylated penicillin-binding protein A from Mycobacterium tuberculosis.

C. Davies, R. Nicholas, A. Fedarovich, 2012, Journal of molecular biology.

Editorial: Bacterial Mechanisms of Antibiotic Resistance: A Structural Perspective

C. Davies, G. Conn, Vassiliy N. Bavro, 2019, Front. Mol. Biosci..