J. Bernatchez

发表

Self-Masked Aldehyde Inhibitors: A Novel Strategy for Inhibiting Cysteine Proteases.

A. Laganowsky, B. Chenna, T. Meek, 2021, Journal of medicinal chemistry.

Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis.

F. Gage, Simon T. Schafer, A. Muotri, 2019, Cell stem cell.

Identification of Leucinostatins from Ophiocordyceps sp. as Antiparasitic Agents against Trypanosoma cruzi

J. McKerrow, R. Cichewicz, L. McCall, 2021, bioRxiv.

1 Dynamics of HCV RNA-dependent RNA Polymerase NS 5 B in Complex with RNA

G. Cosa, J. Bernatchez, P. Karam, 2014 .

Inhibitors of the Hepatitis C Virus RNA-Dependent RNA Polymerase NS5B

J. Bernatchez, Megan H. Powdrill, M. Götte, 2010, Viruses.

The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies.

Lisa C. Wallace, Andrew R. Morton, Qiulian Wu, 2020, Cancer discovery.

Local Phenomena Shape Backyard Soil Metabolite Composition

Hannah Panlilio, R. Cichewicz, L. McCall, 2020, Metabolites.

Insights gained into respiratory infection pathogenesis using lung tissue metabolomics

L. McCall, J. Bernatchez, Jean A. Bernatchez, 2020, PLoS pathogens.

Leveraging Allele-Specific Expression for Therapeutic Response Gene Glioblastoma

Qiulian Wu, Graham P. McVicker, J. Bernatchez, 2021 .

In vitro evaluation of the leishmanicidal potential of selected plant-derived extracts against Leishmania (Leishmania) amazonensis

M. Groppo, J. Bernatchez, L. Magalhães, 2019 .

Mechanism of Action of Methotrexate Against Zika Virus

Davey M. Smith, Michelli F. Oliveira, J. Bernatchez, 2018, bioRxiv.

Characterization of amino acids Arg, Ser and Thr at position 70 within HIV-1 reverse transcriptase

K. Theys, R. Camacho, K. Van Laethem, 2014, Acta clinica Belgica.

Nucleoside analogue inhibitors for Zika virus infection

J. Bernatchez, J. Siqueira-Neto, B. Purse, 2021, Zika Virus Impact, Diagnosis, Control, and Models.

Derivatives of Mesoxalic Acid Block Translocation of HIV-1 Reverse Transcriptase*

D. Hazuda, A. Berghuis, S. Hecht, 2014, The Journal of Biological Chemistry.

Pharmacophore requirements for HIV-1 reverse transcriptase inhibitors that selectively "Freeze" the pre-translocated complex during the polymerization catalytic cycle.

Y. Tsantrizos, J. Bernatchez, M. Götte, 2018, Bioorganic & medicinal chemistry.

Kinase and Histone Deacetylase Hybrid Inhibitors for Cancer Therapy.

Rongshi Li, J. Bernatchez, Y. Luan, 2018, Journal of medicinal chemistry.

Machine Learning Models Identify Inhibitors of SARS-CoV-2

Thomas Rogers, Sean Ekins, Kimberley M. Zorn, 2020, bioRxiv.

Cysteine proteases in protozoan parasites

P. Rosenthal, M. Ndao, S. Reed, 2018, PLoS neglected tropical diseases.

Nucleotide Sugar Pucker Preference Mitigates Excision by HIV-1 RT.

G. Deleavey, M. Damha, M. Parniak, 2015, ACS chemical biology.

A common anti-CMV drug, ganciclovir, inhibits HIV-1 replication in human tissues ex vivo.

L. Margolis, C. Vanpouille, A. Lisco, 2017, AIDS.

Development and Validation of a Phenotypic High-Content Imaging Assay for Assessing the Antiviral Activity of Small-Molecule Inhibitors Targeting Zika Virus

Yan Liu, Rongshi Li, J. Bernatchez, 2018, Antimicrobial Agents and Chemotherapy.

Activity of Selected Nucleoside Analogue ProTides against Zika Virus in Human Neural Stem Cells

J. Rich, J. Bernatchez, J. Siqueira-Neto, 2019, bioRxiv.

Formation of a Quaternary Complex of HIV-1 Reverse Transcriptase with a Nucleotide-competing Inhibitor and Its ATP Enhancer*

J. Bernatchez, M. Nijhuis, D. Jochmans, 2013, The Journal of Biological Chemistry.

Dynamics of Hepatitis C Virus (HCV) RNA-dependent RNA Polymerase NS5B in Complex with RNA*

Jean Bernatchez, Gonzalo Cosa, G. Cosa, 2014, The Journal of Biological Chemistry.

Activity of Selected Nucleoside Analogue ProTides against Zika Virus in Human Neural Stem Cells.

J. Rich, J. Bernatchez, J. Siqueira-Neto, 2019, Viruses.

Drugs for the Treatment of Zika Virus Infection.

Rongshi Li, J. Bernatchez, J. Siqueira-Neto, 2020, Journal of medicinal chemistry.

Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma

Andrew R. Morton, Charles Y. Lin, G. Barnett, 2019, The Journal of experimental medicine.

Leveraging Allele-Specific Expression for Therapeutic Response Gene Discovery in Glioblastoma

Qiulian Wu, Graham P. McVicker, J. Rich, 2021, Cancer Research.

Peptidomimetic Vinyl Heterocycle Inhibitors of Cruzain Effect Anti-Trypanosomal Activity.

J. McKerrow, B. Chenna, T. Meek, 2020, Journal of medicinal chemistry.

Mass Spectrometry-Based Chemical Cartography of a Cardiac Parasitic Infection.

Rob Knight, Pieter C Dorrestein, James T. Morton, 2017, Analytical chemistry.

High-Throughput Screening of the ReFRAME Library Identifies Potential Drug Repurposing Candidates for Trypanosoma cruzi

J. McKerrow, J. Bernatchez, J. Siqueira-Neto, 2019, bioRxiv.

Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics

L. Naesens, E. Arnold, W. Dehaen, 2015, Proceedings of the National Academy of Sciences.

Development and validation of a phenotypic high-content imaging assay for assessing the antiviral activity of small-molecule inhibitors targeting the Zika virus

Yan Liu, Rongshi Li, J. Bernatchez, 2018, bioRxiv.

Scaffold and Parasite Hopping: Discovery of New Protozoal Proliferation Inhibitors.

R. F. Campbell, Ana Rodriguez, J. McKerrow, 2020, ACS medicinal chemistry letters.

Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells.

Qiulian Wu, Xiang-Dong Fu, Ye Zheng, 2021, Cancer discovery.