Lauren R. Blankenship

发表

Self-Masked Aldehyde Inhibitors: A Novel Strategy for Inhibiting Cysteine Proteases.

A. Laganowsky, B. Chenna, T. Meek, 2021, Journal of medicinal chemistry.

A Speedy Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors

Hamed S. Hayatshahi, B. Sankaran, C. Fierke, 2020, bioRxiv.

A Quick Route to Multiple Highly Potent SARS‐CoV‐2 Main Protease Inhibitors **

Hamed S. Hayatshahi, B. Sankaran, C. Fierke, 2020, ChemMedChem.

Repurposing Halicin as a potent covalent inhibitor for the SARS-CoV-2 main protease

D. Russell, Kai S Yang, Lauren R. Blankenship, 2022, Current Research in Chemical Biology.

Antibiotic Adjuvant Activity Revealed in a Photoaffinity Approach to Determine the Molecular Target of Antipyocyanin Compounds.

David H Perlman, Zinan Zhang, Lauren R. Blankenship, 2021, ACS infectious diseases.

A multi-pronged evaluation of aldehyde-based tripeptidyl main protease inhibitors as SARS-CoV-2 antivirals

B. Sankaran, Ge-Shu Yu, Kai S Yang, 2022, European Journal of Medicinal Chemistry.

The P3 O-Tert-Butyl-Threonine is Key to High Cellular and Antiviral Potency for Aldehyde-Based SARS-CoV-2 Main Protease Inhibitors

B. Sankaran, Ge-Shu Yu, Kai S Yang, 2021, bioRxiv.

Repurposing Halicin as a potent covalent inhibitor for the SARS-CoV-2 main protease

D. Russell, Kai S Yang, Lauren R. Blankenship, 2022, Current Research in Chemical Biology.

A Novel Y-Shaped, S-O-N-O-S-Bridged Crosslink between Three Residues C22, C44, and K61 Is a Redox Switch of the SARS-CoV-2 Main Protease

B. Sankaran, C. Fierke, D. Russell, 2022, bioRxiv.

A systematic exploration of boceprevir-based main protease inhibitors as SARS-CoV-2 antivirals

B. Sankaran, Ge-Shu Yu, Kai S Yang, 2022, European Journal of Medicinal Chemistry.

The N-Terminal Carbamate is Key to High Cellular and Antiviral Potency for Boceprevir-Based SARS-CoV-2 Main Protease Inhibitors

B. Sankaran, Ge-Shu Yu, Kai S Yang, 2021, bioRxiv.

A Novel Y-Shaped, S-O-N-O-S-Bridged Cross-Link between Three Residues C22, C44, and K61 Is Frequently Observed in the SARS-CoV-2 Main Protease.

C. Fierke, D. Russell, Kai S Yang, 2023, ACS chemical biology.

Functional characterization of a subtilisin-like serine protease from Vibrio cholerae

Stavroula K. Hatzios, Lauren R. Blankenship, M. Howell, 2019, The Journal of Biological Chemistry.

An Enhanced Hybrid Screening Approach to Identify Potent Inhibitors for the SARS-CoV-2 Main Protease From the NCI Compound Library

Lauren R. Blankenship, W. Liu, Hongbin Wang, 2022, Frontiers in Chemistry.

The Pyrrolysyl-tRNA Synthetase Activity can be Improved by a P188 Mutation that Stabilizes the Full-Length Enzyme.

Lauren R. Blankenship, W. Liu, Xinyu R. Ma, 2022, Journal of molecular biology.

Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease.

Xuping Xie, Lauren R. Blankenship, W. Liu, 2024, Journal of medicinal chemistry.

A Systematic Survey of Reversibly Covalent Dipeptidyl Inhibitors of the SARS-CoV-2 Main Protease

Lauren R. Blankenship, W. Liu, Kaustav Khatua, 2023, bioRxiv.