P. Guedes de Pinho

发表

MDMA hepatotoxicity under heat stress condition: novel insights from in vitro metabolomic studies.

E. Fernandes, F. Carvalho, A. M. Araújo, 2020, Journal of proteome research.

Performance of Anesthetic Depth Indexes in Rabbits under Propofol Anesthesia: Prediction Probabilities and Concentration-effect Relations

Carlos Venâncio, P. Guedes de Pinho, Aura Silva, 2011, Anesthesiology.

Nuclear Magnetic Resonance metabolomics reveals an excretory metabolic signature of renal cell carcinoma

R. Henrique, C. Jerónimo, M. Carvalho, 2016, Scientific Reports.

Metabolomic approaches in the discovery of potential urinary biomarkers of drug-induced liver injury (DILI)

Ana Margarida Araújo, F. Carvalho, A. M. Araújo, 2017, Critical reviews in toxicology.

Metabolomics analysis for biomarker discovery: advances and challenges.

P. Guedes de Pinho, M. Bastos, M. Carvalho, 2012, Current medicinal chemistry.

Characterization of chemical compounds susceptible to be extracted from cork by the wine using GC-MS and 1H NMR metabolomic approaches.

P. Guedes de Pinho, M. Bastos, P. Lopes, 2019, Food chemistry.

Study of major aromatic compounds in port wines from carotenoid degradation.

Judith Monteiro, P. Guedes de Pinho, Carla M Oliveira, 2008, Food chemistry.

3,4-Methylenedioxypyrovalerone (MDPV): in vitro mechanisms of hepatotoxicity under normothermic and hyperthermic conditions

F. Carvalho, A. M. Araújo, M. Carvalho, 2015, Archives of Toxicology.

Editor's Highlight: Characterization of Hepatotoxicity Mechanisms Triggered by Designer Cathinone Drugs (β-Keto Amphetamines).

Ana Margarida Araújo, E. Fernandes, F. Carvalho, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

Methylone and MDPV activate autophagy in human dopaminergic SH-SY5Y cells: a new insight into the context of β-keto amphetamines-related neurotoxicity

J. Duarte, F. Carvalho, G. Correia-da-Silva, 2017, Archives of Toxicology.

Neurotoxicity of β-Keto Amphetamines: Deathly Mechanisms Elicited by Methylone and MDPV in Human Dopaminergic SH-SY5Y Cells.

E. Fernandes, F. Carvalho, M. Carvalho, 2017, ACS chemical neuroscience.

Resistance to oxidation of white wines assessed by voltammetric means.

P. Guedes de Pinho, A. S. Silva Ferreira, Astride Rodrigues, 2007, Journal of agricultural and food chemistry.

Development of a new procedure for the determination of the reactivity of brandies used in wine fortification

V. de Freitas, N. Mateus, P. Guedes de Pinho, 2021, OENO One.

Interaction between hydroxyethyl starch and propofol: computational and laboratorial study

A. Palmeira, P. Amorim, P. Guedes de Pinho, 2014, Journal of biomolecular structure & dynamics.

A Metabolomic Approach for the In Vivo Study of Gold Nanospheres and Nanostars after a Single-Dose Intravenous Administration to Wistar Rats

Ana Margarida Araújo, E. Pereira, S. Gonçalves-Monteiro, 2019, Nanomaterials.

Volatilomics Reveals Potential Biomarkers for Identification of Renal Cell Carcinoma: An In Vitro Approach

Ana Margarida Araújo, R. Henrique, C. Jerónimo, 2020, Metabolites.

Volatile constituents throughout Brassica oleracea L. Var. acephala germination.

J. Pereira, F. Fernandes, P. Andrade, 2009, Journal of agricultural and food chemistry.

Discrimination between the human prostate normal and cancer cell exometabolome by GC-MS

R. Henrique, C. Jerónimo, A. M. Araújo, 2018, Scientific Reports.

NMR-based metabolomics studies of human prostate cancer tissue

P. Guedes de Pinho, M. Bastos, A. R. Lima, 2018, Metabolomics.

Cardiotoxicity of cyclophosphamide’s metabolites: an in vitro metabolomics approach in AC16 human cardiomyocytes

Ana Margarida Araújo, A. M. Araújo, P. Guedes de Pinho, 2022, Archives of Toxicology.

Comprehensive Metabolomics and Lipidomics Profiling of Prostate Cancer Tissue Reveals Metabolic Dysregulations Associated with Disease Development.

R. Henrique, C. Jerónimo, P. Guedes de Pinho, 2021, Journal of proteome research.

Further insights into the role of methional and phenylacetaldehyde in lager beer flavor stability.

P. Guedes de Pinho, A. S. Silva Ferreira, M. A. Soares Da Costa, 2004, Journal of agricultural and food chemistry.

Relationship between potentiometric measurements, sensorial analysis, and some substances responsible for aroma degradation of white wines.

P. Guedes de Pinho, T. Hogg, Carla M Oliveira, 2003, Journal of agricultural and food chemistry.

Influence of some technological parameters on the formation of dimethyl sulfide, 2-mercaptoethanol, methionol, and dimethyl sulfone in port wines.

P. Guedes de Pinho, T. Hogg, P. Rodrigues, 2003, Journal of agricultural and food chemistry.

Hepatic Metabolic Derangements Triggered by Hyperthermia: An In Vitro Metabolomic Study

F. Carvalho, A. M. Araújo, M. Enea, 2019, Metabolites.

Sunitinib versus Pazopanib Dilemma in Renal Cell Carcinoma: New Insights into the In Vitro Metabolic Impact, Efficacy, and Safety

P. Guedes de Pinho, M. J. Valente, J. Pinto, 2022, International journal of molecular sciences.

Port wine.

P. Guedes de Pinho, N. Moreira, 2011, Advances in food and nutrition research.

Postmortem redistribution of tramadol and O-desmethyltramadol.

F. Carvalho, H. Teixeira, P. Guedes de Pinho, 2013, Journal of analytical toxicology.

Carotenoid compounds in grapes and their relationship to plant water status.

P. Guedes de Pinho, T. Hogg, A. S. Silva Ferreira, 2003, Journal of agricultural and food chemistry.

Khat and synthetic cathinones: a review

F. Carvalho, M. Carvalho, P. Guedes de Pinho, 2013, Archives of Toxicology.

Development of a potentiometric method to measure the resistance to oxidation of white wines and the antioxidant power of their constituents.

P. Guedes de Pinho, T. Hogg, Carla M Oliveira, 2002, Journal of agricultural and food chemistry.

GC–MS metabolomics reveals disturbed metabolic pathways in primary mouse hepatocytes exposed to subtoxic levels of 3,4-methylenedioxymethamphetamine (MDMA)

E. Fernandes, F. Carvalho, A. M. Araújo, 2018, Archives of Toxicology.

Cocaine-induced kidney toxicity: an in vitro study using primary cultured human proximal tubular epithelial cells

F. Carvalho, R. Henrique, M. Carvalho, 2012, Archives of Toxicology.

Diet aid or aid to die: an update on 2,4-dinitrophenol (2,4-DNP) use as a weight-loss product

F. Carvalho, P. Guedes de Pinho, M. Bastos, 2020, Archives of Toxicology.

Evaluation of some carotenoids in grapes by reversed- and normal-phase liquid chromatography: a qualitative analysis.

P. Guedes de Pinho, M. Oliveira, A. Ferreira, 2004, Journal of agricultural and food chemistry.

Chemical assessment and in vitro antioxidant capacity of Ficus carica latex.

J. Pereira, P. Andrade, P. Valentão, 2010, Journal of agricultural and food chemistry.

The hallucinogenic world of tryptamines: an updated review

F. Carvalho, A. M. Araújo, M. Carvalho, 2015, Archives of Toxicology.

Enantioselectivity of Pentedrone and Methylone on Metabolic Profiling in 2D and 3D Human Hepatocyte-like Cells

P. Guedes de Pinho, F. Remião, C. Fernandes, 2022, Pharmaceuticals.

The hallucinogenic world of tryptamines: an updated review

Ana Margarida Araújo, F. Carvalho, A. M. Araújo, 2015, Archives of Toxicology.

Effect of temperature on 3,4-methylenedioxypyrovalerone (MDPV)-induced metabolome disruption in primary mouse hepatic cells.

F. Carvalho, A. M. Araújo, P. Guedes de Pinho, 2020, Toxicology.

Lycopersicon esculentum seeds: an industrial byproduct as an antimicrobial agent.

M. Taveira, P. Andrade, P. Valentão, 2010, Journal of agricultural and food chemistry.

Brassica oleracea L. Var. costata DC and Pieris brassicae L. aqueous extracts reduce methyl methanesulfonate-induced DNA damage in V79 hamster lung fibroblasts.

J. Teixeira, P. Andrade, P. Valentão, 2012, Journal of agricultural and food chemistry.

Diet aid or aid to die: an update on 2,4-dinitrophenol (2,4-DNP) use as a weight-loss product

F. Carvalho, P. Guedes de Pinho, M. Bastos, 2020, Archives of Toxicology.

In vitro interactions between the ectomycorrhizal Pisolithus tinctorius and the saprotroph Hypholoma fasciculare fungi: morphological aspects and volatile production

R. Malheiro, R. Tavares, P. Baptista, 2021, Mycology.

Volatile Profiling of Kiwifruits (Actinidia deliciosa ‘Hayward’) Evaluated by HS-SPME and GC-IT/MS: Influence of Ripening, Training System and Storage

I. Ferreira, P. Guedes de Pinho, Ana Aguiar, 2012, Food and Bioprocess Technology.

Mineral Content and Volatile Profiling of Prunus avium L. (Sweet Cherry) By-Products from Fundão Region (Portugal)

G. Alves, J. Flores-Félix, E. Pinto, 2022, Foods.

Raising awareness of new psychoactive substances: chemical analysis and in vitro toxicity screening of ‘legal high’ packages containing synthetic cathinones

Ana Margarida Araújo, F. Carvalho, H. Gaspar, 2014, Archives of Toxicology.

Update on 1-benzylpiperazine (BZP) party pills

M. Carvalho, P. Guedes de Pinho, M. Bastos, 2013, Archives of Toxicology.

Heavy sulphur compounds, higher alcohols and esters production profile of Hanseniaspora uvarum and Hanseniaspora guilliermondii grown as pure and mixed cultures in grape must.

P. Guedes de Pinho, T. Hogg, I. Vasconcelos, 2008, International journal of food microbiology.

GC determination of acetone, acetaldehyde, ethanol, and methanol in biological matrices and cell culture.

Agostinho Santos, Teresa Magalhães, Susana Casal, 2009, Journal of chromatographic science.

Sensory attributes and volatile composition of a dry white wine under different packing configurations

P. Guedes de Pinho, P. Lopes, M. Cabral, 2017, Journal of Food Science and Technology.

GC–MS metabolomics reveals disturbed metabolic pathways in primary mouse hepatocytes exposed to subtoxic levels of 3,4-methylenedioxymethamphetamine (MDMA)

E. Fernandes, F. Carvalho, A. M. Araújo, 2018, Archives of Toxicology.

Identification of key odorants related to the typical aroma of oxidation-spoiled white wines.

P. Guedes de Pinho, T. Hogg, A. S. Silva Ferreira, 2003, Journal of agricultural and food chemistry.

Carotenoid, chlorophyll, and chlorophyll-derived compounds in grapes and port wines.

P. Guedes de Pinho, M. M. Mendes-Pinto, A. S. Silva Ferreira, 2005, Journal of agricultural and food chemistry.

Analytical investigation of legal high products containing Salvia divinorum traded in smartshops and internet.

F. Carvalho, M. de Lourdes Bastos, P. Guedes de Pinho, 2014, Forensic science international.

Urinary Volatilomics Unveils a Candidate Biomarker Panel for Noninvasive Detection of Clear Cell Renal Cell Carcinoma.

R. Henrique, C. Jerónimo, P. Guedes de Pinho, 2021, Journal of proteome research.

GC‐MS metabolomics‐based approach for the identification of a potential VOC‐biomarker panel in the urine of renal cell carcinoma patients

Rui Henrique, Carmen Jerónimo, Maria de Lourdes Bastos, 2017, Journal of cellular and molecular medicine.

3,4-Methylenedioxypyrovalerone (MDPV): in vitro mechanisms of hepatotoxicity under normothermic and hyperthermic conditions

Ana Margarida Araújo, F. Carvalho, A. M. Araújo, 2016, Archives of Toxicology.

Further insight into the latex metabolite profile of Ficus carica.

J. Pereira, P. Andrade, P. Valentão, 2010, Journal of agricultural and food chemistry.

Biomarker Discovery in Human Prostate Cancer: an Update in Metabolomics Studies

Maria de Lourdes Bastos, P. Guedes de Pinho, M. Bastos, 2016, Translational oncology.

Volatile profile of cork as a tool for classification of natural cork stoppers.

P. Guedes de Pinho, M. Bastos, P. Lopes, 2021, Talanta.

Occupational exposure to formaldehyde and early biomarkers of cancer risk, immunotoxicity and susceptibility.

J. Teixeira, C. Costa, P. Guedes de Pinho, 2019, Environmental research.

Pharmacometabolomics Applied to Personalized Medicine in Urological Cancers

P. Guedes de Pinho, J. Pinto, M. Carvalho, 2022, Pharmaceuticals.

In vivo toxicometabolomics reveals multi-organ and urine metabolic changes in mice upon acute exposure to human-relevant doses of 3,4-methylenedioxypyrovalerone (MDPV)

Ana Margarida Araújo, J. Duarte, F. Carvalho, 2020, Archives of Toxicology.

The Impact of Different Closures on the Flavor Composition of Wines during Bottle Aging

P. Guedes de Pinho, M. Bastos, P. Lopes, 2021, Foods.

GC-MS Metabolomics Reveals Distinct Profiles of Low- and High-Grade Bladder Cancer Cultured Cells

R. Henrique, C. Jerónimo, A. M. Araújo, 2019, Metabolites.

Toxicometabolomics: Small Molecules to Answer Big Toxicological Questions

Ana Margarida Araújo, A. M. Araújo, P. Guedes de Pinho, 2021, Metabolites.

Identification of a biomarker panel for improvement of prostate cancer diagnosis by volatile metabolic profiling of urine

D. Barros-Silva, R. Henrique, C. Jerónimo, 2019, British Journal of Cancer.

Analysis of extracellular metabolome by HS-SPME/GC-MS: Optimization and application in a pilot study to evaluate galactosamine-induced hepatotoxicity.

F. Carvalho, A. M. Araújo, P. Guedes de Pinho, 2018, Toxicology letters.

Discovery of Volatile Biomarkers for Bladder Cancer Detection and Staging through Urine Metabolomics

R. Henrique, C. Jerónimo, P. Guedes de Pinho, 2021, Metabolites.

A Panel of Urinary Volatile Biomarkers for Differential Diagnosis of Prostate Cancer from Other Urological Cancers

R. Henrique, C. Jerónimo, P. Guedes de Pinho, 2020, Cancers.

Discrimination between the human prostate normal and cancer cell exometabolome by GC-MS

Ana Margarida Araújo, R. Henrique, C. Jerónimo, 2018, Scientific Reports.

Chiral Resolution and Enantioselectivity of Synthetic Cathinones: A Brief Review.

P. Guedes de Pinho, F. Remião, C. Fernandes, 2018, Journal of analytical toxicology.

Determination of carotenoid profiles in grapes, musts, and fortified wines from Douro varieties of Vitis vinifera.

P. Guedes de Pinho, T. Hogg, J. G. Benı́tez, 2001, Journal of agricultural and food chemistry.

Port wine.

P. Guedes de Pinho, N. Moreira, 2011, Advances in food and nutrition research.

Oxidation management of white wines using cyclic voltammetry and multivariate process monitoring.

V. V. Lopes, R. C. Martins, P. Guedes de Pinho, 2008, Journal of agricultural and food chemistry.

Cocaine-induced kidney toxicity: an in vitro study using primary cultured human proximal tubular epithelial cells

F. Carvalho, R. Henrique, M. Carvalho, 2011, Archives of Toxicology.

Development and validation of automatic HS-SPME with a gas chromatography-ion trap/mass spectrometry method for analysis of volatiles in wines.

S. Leite, P. Guedes de Pinho, N. Moreira, 2012, Talanta.

The Impact of Storage Conditions and Bottle Orientation on the Evolution of Phenolic and Volatile Compounds of Vintage Port Wine

V. de Freitas, N. Mateus, P. Guedes de Pinho, 2022, Foods.

Advances and Perspectives in Prostate Cancer Biomarker Discovery in the Last 5 Years through Tissue and Urine Metabolomics

P. Guedes de Pinho, M. Bastos, A. R. Lima, 2021, Metabolites.

GC-MS-Based Endometabolome Analysis Differentiates Prostate Cancer from Normal Prostate Cells

R. Henrique, C. Jerónimo, A. M. Araújo, 2018, Metabolites.

Enantioselectivity on the absorption of methylone and pentedrone using Caco-2 cell line: Development and validation of an UHPLC method for cathinones quantification.

P. Guedes de Pinho, F. Remião, C. Fernandes, 2020, Toxicology and applied pharmacology.

Variation in the Phenolic Composition of Cork Stoppers from Different Geographical Origins.

H. Pereira, V. de Freitas, N. Mateus, 2020, Journal of agricultural and food chemistry.

Assessment of oxidation compounds in oaked Chardonnay wines: A GC-MS and 1H NMR metabolomics approach.

V. de Freitas, P. Guedes de Pinho, J. Azevedo, 2018, Food chemistry.

Raising awareness of new psychoactive substances: chemical analysis and in vitro toxicity screening of ‘legal high’ packages containing synthetic cathinones

F. Carvalho, H. Gaspar, A. M. Araújo, 2015, Archives of Toxicology.

NMR-based metabolomics studies of human prostate cancer tissue

P. Guedes de Pinho, M. Bastos, A. R. Lima, 2018, Metabolomics.

Update on 1-benzylpiperazine (BZP) party pills

M. Carvalho, P. Guedes de Pinho, M. Bastos, 2013, Archives of Toxicology.

Multidimensional Health Impact of Multicomponent Exercise and Sustainable Healthy Diet Interventions in the Elderly (MED-E): Study Protocol

A. Pizarro, P. Padrão, P. Moreira, 2023, Nutrients.

MnTnHex-2-PyP5+ Displays Anticancer Properties and Enhances Cisplatin Effects in Non-Small Cell Lung Cancer Cells

R. Rosell, I. Batinic-Haberle, I. Spasojević, 2022, Antioxidants.

Cardiotoxicity of cyclophosphamide’s metabolites: an in vitro metabolomics approach in AC16 human cardiomyocytes

F. Carvalho, A. M. Araújo, P. Guedes de Pinho, 2022, Archives of Toxicology.

The Redox-Active Manganese(III) Porphyrin, MnTnBuOE-2-PyP5+, Impairs the Migration and Invasion of Non-Small Cell Lung Cancer Cells, Either Alone or Combined with Cisplatin

R. Rosell, I. Batinic-Haberle, I. Spasojević, 2023, Cancers.

Effect of Hemodynamic Changes in Plasma Propofol Concentrations Associated with Knee-Chest Position in Spinal Surgery: A Prospective Study

D. Chaló, P. Amorim, P. Guedes de Pinho, 2019, Anesthesiology and pain medicine.

Effect of some viticultural parameters on the grape carotenoid profile.

P. Guedes de Pinho, Carla M Oliveira, A. Ferreira, 2004, Journal of agricultural and food chemistry.

Metabolic signature biomarkers for predicting the recurrence of urological cancers.

M. de Lourdes Bastos, P. Guedes de Pinho, J. Pinto, 2023, Clinica chimica acta; international journal of clinical chemistry.

Methylone and MDPV activate autophagy in human dopaminergic SH-SY5Y cells: a new insight into the context of β-keto amphetamines-related neurotoxicity

J. Duarte, F. Carvalho, G. Correia-da-Silva, 2017, Archives of Toxicology.

Postmortem redistribution of tramadol and O-desmethyltramadol.

F. Carvalho, H. Teixeira, P. Guedes de Pinho, 2013, Journal of analytical toxicology.

Identification of key neuronal mechanisms triggered by dimethyl fumarate in SH-SY5Y human neuroblastoma cells through a metabolomic approach

A. M. Araújo, P. Guedes de Pinho, H. Carmo, 2024, Archives of toxicology.

Metabolomic Signatures of Treatment Response in Bladder Cancer

P. Guedes de Pinho, J. Pinto, Tiago Vieira de Sousa, 2023, International journal of molecular sciences.

Editor's Highlight: Characterization of Hepatotoxicity Mechanisms Triggered by Designer Cathinone Drugs (β-Keto Amphetamines).

E. Fernandes, F. Carvalho, A. M. Araújo, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

Lycopersicon esculentum seeds: an industrial byproduct as an antimicrobial agent.

M. Taveira, P. Andrade, P. Valentão, 2010, Journal of agricultural and food chemistry.

A Clinically Relevant Dosage of Mitoxantrone Disrupts the Glutathione and Lipid Metabolic Pathways of the CD-1 Mice Brain: A Metabolomics Study

F. Carvalho, E. Fernandes, P. Guedes de Pinho, 2023, International journal of molecular sciences.

Exploiting volatile fingerprints for bladder cancer diagnosis: A scoping review of metabolomics and sensor-based approaches.

P. Guedes de Pinho, J. Pinto, Félix Carvalho, 2023, Talanta.

Metabolomics perspectives of the ecotoxicological risks of polycyclic aromatic hydrocarbons: A scoping review.

P. Guedes de Pinho, D. Dias da Silva, J. Pinto, 2024, Environmental research.

Mediterranean Diet-Based Sustainable Healthy Diet and Multicomponent Training Combined Intervention Effect on Body Composition, Anthropometry, and Physical Fitness in Healthy Aging

P. Guedes de Pinho, J. Pinto, Joana Sampaio, 2024, Nutrients.