H. Ohshima

H. Bartsch, M. Tatematsu, H. Ohshima, 1992, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Urinary excretion of N‐nitrosamino acids and nitrate by inhabitants of high‐ and low‐risk areas for stomach cancer in Poland

H. Bartsch, W. Zatónski, H. Ohshima, 1989, International journal of cancer.

Evidence of potential tumour-initiating and tumour-promoting activities of hickory smoke condensate when given alone or with nitrite to rats.

H. Bartsch, H. Ohshima, T. Matsushima, 1989, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Unusually high levels of carcinogenic tobacco-specific nitrosamines in Sudan snuff (toombak).

H. Bartsch, E. Faustman, H. Ohshima, 1991, Carcinogenesis.

Volatile nitrosamine levels in common foods from tunisia, south china and greenland, high‐risk areas for nasopharyngeal carcinoma (NPC)

H. Bartsch, G. de‐Thé, H. Ohshima, 1987, International journal of cancer.

Endogenous nitrosation in the oral cavity of chewers while chewing betel quid with or without tobacco.

H. Bartsch, H. Ohshima, J. Nair, 1987, IARC scientific publications.

Endogenous nitrosamines and liver fluke as risk factors for cholangiocarcinoma in Thailand.

H. Bartsch, M. Khlat, H. Ohshima, 1991, IARC scientific publications.

8-nitroguanine, a product of nitrative DNA damage caused by reactive nitrogen species: formation, occurrence, and implications in inflammation and carcinogenesis.

T. Akaike, H. Ohshima, T. Sawa, 2006, Antioxidants & redox signaling.

Relationships between the synthesis of N-nitrosodimethylamine and immune responses to chronic infection with the carcinogenic parasite, Opisthorchis viverrini, in men.

H. Bartsch, H. Esumi, M. Haswell-Elkins, 1998, Carcinogenesis.

Exposure to N-nitroso compounds in a population of high liver cancer regions in Thailand: volatile nitrosamine (VNA) levels in Thai food.

L. Caplan, H. Ohshima, M. Suttajit, 1999, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Cholangiocarcinoma: epidemiology, mechanisms of carcinogenesis and prevention.

D. Parkin, H. Ohshima, P. Srivatanakul, 1993, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Recent studies on N-nitroso compounds as possible etiological factors in oesophageal cancer.

H. Bartsch, H. Ohshima, S. Lu, 1984, IARC scientific publications.

Inhibitors of endogenous nitrosation. Mechanisms and implications in human cancer prevention.

H. Bartsch, H. Ohshima, B. Pignatelli, 1988, Mutation research.

Bacterial formation of N-nitroso compounds in the rat stomach after omeprazole-induced achlorhydria.

H. Bartsch, H. Ohshima, J. Béréziat, 1991, IARC scientific publications.

Exposure to N-nitrosamines and other risk factors for gastric cancer in Costa Rican children.

N. Muñoz, F. El Ghissassi, H. Ohshima, 1991, IARC scientific publications.

Nitric oxide involvement in tumor-induced immunosuppression.

P. Lagadec, H. Ohshima, P. Lejeune, 1994, Journal of immunology.

Ortho- and meta-tyrosine formation from phenylalanine in human saliva as a marker of hydroxyl radical generation during betel quid chewing.

H. Bartsch, H. Ohshima, J. Nair, 1995, Carcinogenesis.

Inhibition of L-Arginine Metabolizing Enzymes by L-Arginine-Derived Advanced Glycation End Products

R. Nagai, N. Miyoshi, H. Ohshima, 2010, Journal of clinical biochemistry and nutrition.

Analysis of 3-nitrotyrosine in biological fluids and protein hydrolyzates by high-performance liquid chromatography using a postseparation, on-line reduction column and electrochemical detection: results with various nitrating agents.

H. Ohshima, H. Mower, B. Pignatelli, 1999, Nitric oxide : biology and chemistry.

Nitric oxide nitrates tyrosine residues of tumor-suppressor p53 protein in MCF-7 cells.

P. Hainaut, H. Ohshima, L. Chazotte-Aubert, 2000, Biochemical and biophysical research communications.

Nitrotyrosine as a new marker for endogenous nitrosation and nitration.

H. Bartsch, H. Ohshima, M. Friesen, 1991, IARC scientific publications.

Increased Oxidative and Nitrative Stress in Human Stomach Associated with cagA+ Helicobacter pylori Infection and Inflammation

H. Ohshima, Chun-Qi Li, B. Pignatelli, 2001, Digestive Diseases and Sciences.

Nitric oxide synergistically enhances DNA strand breakage induced by polyhydroxyaromatic compounds, but inhibits that induced by the Fenton reaction.

H. Ohshima, Yumiko Yoshie, Y. Yoshie, 1997, Archives of biochemistry and biophysics.

Inverse correlation between alcohol consumption and lymphocyte levels of 8-hydroxydeoxyguanosine in humans.

H. Boeing, H. Ohshima, R. Kaaks, 2001, Carcinogenesis.

Oxidative Stress in Gastric Mucosa of Asymptomatic Humans Infected with Helicobacter pylori: Effect of Bacterial Eradication

M. Stolte, C. Felley, G. V. van Melle, 2002, Helicobacter.

Detection of peroxynitrite-induced protein and DNA modifications.

S. Lorch, C. Szabó, H. Ischiropoulos, 2002, Methods in molecular biology.

Formation of 8‐nitroguanine in DNA treated with peroxynitrite in vitro and its rapid removal from DNA by depurination

H. Ohshima, V. Yermilov, J. Rubio, 1995, FEBS letters.

Nitration and nitrosation of N-acetyl-L-tryptophan and tryptophan residues in proteins by various reactive nitrogen species.

Toshinori Suzuki, H. Ohshima, T. Sawa, 2004, Free radical biology & medicine.

Occurrence of cytotoxic 9-oxononanoyl secosterol aldehydes in human low-density lipoprotein.

Susumu Tomono, N. Miyoshi, H. Ohshima, 2013, Free radical biology & medicine.

Development and application of a method for identification of isothiocyanate-targeted molecules in colon cancer cells.

Yoshimasa Nakamura, Susumu Tomono, N. Miyoshi, 2012, Analytical biochemistry.

Dysregulation of dimethylargininedimethylaminohydrolase/asymmetric dimethylarginine pathway in rat type II diabetic nephropathy

H. Kanazawa, Susumu Tomono, N. Miyoshi, 2012, Journal of clinical biochemistry and nutrition.

Differences in oxidative stress dependence between gastric adenocarcinoma subtypes.

J. Estève, S. Toyokuni, H. Ohshima, 2006, World journal of gastroenterology.

Human beta defensin-1 regulates the development of tight junctions in cultured human epidermal keratinocytes.

S. Hirakawa, H. Ohshima, Y. Kitajima, 2013, Journal of dermatological science.

Formation of 8-nitroguanosine in cellular RNA as a biomarker of exposure to reactive nitrogen species.

H. Nishino, H. Ohshima, M. Masuda, 2002, Chemico-biological interactions.

Coexpression of Interleukin-8 and Inducible Nitric Oxide Synthase in Gastric Mucosa Infected with cagA+ Helicobacter pylori

H. Ohshima, Chun-Qi Li, B. Pignatelli, 2004, Digestive Diseases and Sciences.

Xanthine oxidase converts nitric oxide to nitroxyl that inactivates the enzyme.

H. Ohshima, M. Saleem, 2004, Biochemical and biophysical research communications.

A correlation study on urinary excretion of N-nitroso compounds and cancer mortality in China: interim results.

R. Peto, H. Bartsch, H. Ohshima, 1987, IARC scientific publications.

Urinary excretion of N-nitrosamino acids and nitrate by inhabitants in high- and low-risk areas for stomach cancer in northern Japan.

H. Bartsch, H. Ohshima, P. Ziegler, 1987, IARC scientific publications.

Quantitative estimation of endogenous nitrosation in humans by monitoring N-nitrosoproline excreted in the urine.

H. Bartsch, H. Ohshima, 1981, Cancer research.

Human exposure to endogenous N-nitroso compounds: quantitative estimates in subjects at high risk for cancer of the oral cavity, oesophagus, stomach and urinary bladder.

H. Bartsch, H. Ohshima, B. Pignatelli, 1989, Cancer surveys.

DNA Damage Induced by Reactive Nitrogen Species

P. Hainaut, H. Ohshima, B. Pignatelli, 1998 .

Nitrotyrosine as a new marker for endogenous nitrosation and nitration of proteins.

H. Bartsch, H. Ohshima, H Bartsch, 1990, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Increased risk of intestinal type of gastric adenocarcinoma in Japanese women associated with long forms of CCTTT pentanucleotide repeat in the inducible nitric oxide synthase promoter.

T. Katoh, H. Tazawa, H. Ohshima, 2005, Cancer letters.

Formation of spiroiminodihydantoin nucleoside by reaction of 8-oxo-7,8-dihydro-2'-deoxyguanosine with hypochlorous acid or a myeloperoxidase-H(2)O(2)-Cl(-) system.

H. Ohshima, M. Friesen, M. Masuda, 2001, Chemical research in toxicology.

Dose-Response Study of N-Nitrosoproline Formation in Rats and a Deduced Kinetic Model for Predicting Carcinogenic Effects Caused by Endogenous Nitrosation1

H. Bartsch, H. Ohshima, G. Mahon, 2006 .

Characterization of bacterial cytochrome cd(1)-nitrite reductase as one enzyme responsible for catalysis of nitrosation of secondary amines.

H. Bartsch, H. Ohshima, Y. Henry, 1996, Carcinogenesis.

Nitrosamine formation by denitrifying and non-denitrifying bacteria: implication of nitrite reductase and nitrate reductase in nitrosation catalysis.

H. Bartsch, H. Ohshima, S. Calmels, 1988, Journal of general microbiology.

Levels of mutagens in the urine of smokers of black and blond tobacco correlate with their risk of bladder cancer.

P. Vineis, H. Bartsch, J. Estève, 1989, Carcinogenesis.

Altered Expression of Fas (APO-1, CD95) and Fas Ligand in the Liver of Mice Infected with Schistosoma Japonicum and Schistosoma Mansoni: Implications for Liver Carcinogenesis.

H. Ohgaki, H. Ohshima, Y. Tohma, 2002, Asian Pacific journal of cancer prevention : APJCP.

Food Extracts from High Risk Areas for NPC Induce an EBV Early Promoter

H. Bartsch, A. Polack, G. Bornkamm, 1989 .

Implications of cholesterol autoxidation products in the pathogenesis of inflammatory diseases.

L. Iuliano, Susumu Tomono, N. Miyoshi, 2014, Biochemical and biophysical research communications.

Analysis of oxidized and nitrated proteins in plasma and tissues as biomarkers for exposure to reactive oxygen and nitrogen species.

P. Boffetta, S. Baflast, H. Ohshima, 2002, IARC scientific publications.

Increased nitrosamine and nitrate biosynthesis mediated by nitric oxide synthase induced in hamsters infected with liver fluke (Opisthorchis viverrini).

H. Bartsch, H. Ohshima, V. Vatanasapt, 1994, Carcinogenesis.

Marked increase in urinary excretion of nitrate and N-nitrosothioproline in the osteogenic disordered syndrome rats, lacking ascorbic acid biosynthesis, by administration of lipopolysaccharide and thioproline.

T. Sugimura, H. Esumi, H. Ohshima, 1995, Carcinogenesis.

L-arginine-dependent formation of N-nitrosamines by the cytosol of macrophages activated with lipopolysaccharide and interferon-gamma.

T. Sugimura, H. Esumi, H. Ohshima, 1991, Carcinogenesis.

N-nitrosamine formation in urinary-tract infections.

H. Bartsch, H. Ohshima, B. Pignatelli, 1987, IARC scientific publications.

Detection of certain peroxynitrite-induced DNA modifications.

C. Szabó, L. Virág, H. Ohshima, 2002, Methods in molecular biology.

Inhibition of endothelial- and neuronal-type, but not inducible-type, nitric oxide synthase by the oxidized cholesterol metabolite secosterol aldehyde: Implications for vascular and neurodegenerative diseases

Susumu Tomono, N. Miyoshi, H. Ohshima, 2011, Journal of clinical biochemistry and nutrition.

Biochemical studies on the catalysis of nitrosation by bacteria.

H. Rosenkranz, H. Bartsch, H. Ohshima, 1987, Carcinogenesis.

III.3.b GC-TEA determination of N-nitrosoproline in urine to provide an index for endogenous N-nitrosation.

H. Ohshima, 1983, IARC scientific publications.

Bacterial formation of N-nitroso compounds from administered precursors in the rat stomach after omeprazole-induced achlorhydria.

H. Bartsch, H. Ohshima, J. Béréziat, 1991, Carcinogenesis.

In-vivo nitrosation, precancerous lesions and cancers of the gastrointestinal tract. On-going studies and preliminary results.

N. Muñoz, H. Bartsch, H. Ohshima, 1984, IARC scientific publications.

Dose-response study of N-nitrosoproline formation in rats and a deduced kinetic model for predicting carcinogenic effects caused by endogenous nitrosation.

H. Bartsch, H. Ohshima, J. Wahrendorf, 1983, Cancer research.

Presence in human urine of a new N-nitroso compound, N-nitrosothiazolidine 4-carboxylic acid.

H. Bartsch, H. Ohshima, M. Friesen, 1983, Cancer letters.

Inhibitory effect of betel nut extracts on endogenous nitrosation in humans.

H. Bartsch, H. Stich, H. Ohshima, 1983, Journal of the National Cancer Institute.

Monitoring N-nitrosamino acids excreted in the urine and feces of rats as an index for endogenous nitrosation.

H. Bartsch, H. Ohshima, J. Béréziat, 1982, Carcinogenesis.

In vivo nitrosoproline formation and other risk factors in Costa Rican children from high- and low-risk areas for gastric cancer.

N. Muñoz, H. Bartsch, H. Ohshima, 1993, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Markers for intragastric nitrosamine formation and resulting DNA damage

H. Ohshima, 1988 .

Intragastric nitrosation and precancerous lesions of the gastrointestinal tract: testing of an etiological hypothesis.

N. Muñoz, H. Ohshima, M. Crespi, 1987, IARC scientific publications.

Increased endogenous N-nitrosamine and nitrate formation by induction of nitric oxide synthase in rats with acute hepatic injury caused by Propionibacterium acnes and lipopolysaccharide administration.

H. Bartsch, H. Ohshima, I. Brouet, 1993, Carcinogenesis.

Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis.

H. Bartsch, H. Ohshima, 1994, Mutation research.

8‐Chloro‐dGTP, a hypochlorous acid‐modified nucleotide, is hydrolyzed by hMTH1, the human MutT homolog

Y. Nakabeppu, Toshinori Suzuki, H. Ohshima, 2002, FEBS letters.

Quantitative estimation of endogenous N-nitrosation in humans by monitoring N-nitrosoproline in urine.

H. Bartsch, H. Ohshima, 1999, Methods in enzymology.

Identification of inducible calmodulin-dependent nitric oxide synthase in the liver of rats.

H. Kawasaki, H. Esumi, H. Ohshima, 1992, The Journal of biological chemistry.

Occurrence in human urine of new sulphur-containing N-nitrosamino acids N-nitrosothiazolidine 4-carboxylic acid and its 2-methyl derivative, and their formation

H. Bartsch, H. Ohshima, M. Friesen, 2004, Journal of Cancer Research and Clinical Oncology.

Carcinogenic tobacco-specific nitrosamines are present at unusually high levels in the saliva of oral snuff users in Sudan.

H. Bartsch, E. Faustman, H. Ohshima, 1992, Carcinogenesis.

Identification, occurrence and mutagenicity in Salmonella typhimurium of two synthetic nitroarenes, musk ambrette and musk xylene, in Indian chewing tobacco and betel quid.

H. Bartsch, H. Ohshima, J. Nair, 1986, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Curcumin, an anti-tumour promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages.

H. Ohshima, I. Brouet, 1995, Biochemical and biophysical research communications.

Chemoprevention of Azoxymethane/Dextran Sodium Sulfate–Induced Mouse Colon Carcinogenesis by Freeze-Dried Yam Sanyaku and Its Constituent Diosgenin

Takuji Tanaka, K. Wakabayashi, Ryota Mabuchi, 2011, Cancer Prevention Research.

Nitrative DNA damage in inflammation and its possible role in carcinogenesis.

H. Ohshima, T. Sawa, 2006, Nitric oxide : biology and chemistry.

Inhibition by Polyphenolic Phytochemicals and Sulfurous Compounds of the Formation of 8-Chloroguanosine Mediated by Hypochlorous Acid, Human Myeloperoxidase, and Activated Human Neutrophils

Toshinori Suzuki, H. Ohshima, T. Nakano, 2012, Bioscience, biotechnology, and biochemistry.

DNA damage induced by peroxynitrite: subsequent biological effects.

C. Szabó, H. Ohshima, Csaba Szabo, 1997, Nitric oxide : biology and chemistry.

The enhancement of the oral bioavailability of γ-tocotrienol in mice by γ-cyclodextrin inclusion.

T. Yano, Susumu Tomono, N. Miyoshi, 2011, The Journal of nutritional biochemistry.

Increased risk of gastric cancer in Japanese subjects is associated with microsatellite polymorphisms in the heme oxygenase-1 and the inducible nitric oxide synthase gene promoters.

T. Katoh, H. Ohshima, T. Sawa, 2008, Cancer letters.

Prevention of human cancer by modulation of chronic inflammatory processes.

H. Tazawa, H. Ohshima, B. Sylla, 2005, Mutation research.

Chemical basis of inflammation-induced carcinogenesis.

Tomohiro Sawa, H. Ohshima, T. Sawa, 2003, Archives of biochemistry and biophysics.

Geographic association between urinary excretion of N‐nitroso compounds and oesophageal cancer mortality in china

T C Campbell, R Peto, Y Wu, 1993, International journal of cancer.

Urinary excretion of N-nitrosamino acids and nitrate by inhabitants of high- and low-risk areas for esophageal cancer in Northern China: endogenous formation of nitrosoproline and its inhibition by vitamin C.

M. Blettner, H. Bartsch, H. Ohshima, 1986, Cancer research.

Identification and occurrence of two new N-nitrosamino acids in tobacco products: 3-(N-nitroso-N-methylamino)propionic acid and 4-(N-nitroso-N-methylamino)butyric acid.

H. Bartsch, H. Bartsch, H. Ohshima, 1985, Cancer letters.

Antioxidant and pro-oxidant actions of flavonoids: effects on DNA damage induced by nitric oxide, peroxynitrite and nitroxyl anion.

H. Ohshima, I. Gilibert, Yumiko Yoshie, 1998, Free radical biology & medicine.

Urinary markers for measuring exposure to endogenous and exogenous alkylating agents and precursors.

H. Bartsch, H. Ohshima, D. Shuker, 1993, Environmental health perspectives.

ATP depletion alters the mode of cell death induced by benzyl isothiocyanate.

Yoshimasa Nakamura, T. Osawa, Y. Murata, 2008, Biochimica et biophysica acta.

Tobacco-specific and betel nut-specific N-nitroso compounds: occurrence in saliva and urine of betel quid chewers and formation in vitro by nitrosation of betel quid.

H. Bartsch, H. Ohshima, J. Nair, 1985, Carcinogenesis.

Expression of Nitric Oxide Synthase Isoforms in Bone and Bone Cell Cultures

J. Pollock, S. Ralston, H. Ohshima, 1997, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

1 INFECTION , INFLAMMATION , AND CANCER : OVERVIEW

Susumu Tomono, N. Miyoshi, H. Ohshima, 2013 .

Activities of Hexokinase and Glucose Dehydrogenase in Fish Liver

H. Ohshima, F. Nagayama, T. Takeuchi, 1973 .

Volatile nitrosamine levels and genotoxicity of food samples from high‐risk areas for nasopharyngeal carcinoma before and after nitrosation

H. Bartsch, Y. Zeng, H. Ohshima, 1989, International journal of cancer.

Nitrated and oxidized plasma proteins in smokers and lung cancer patients.

W. Ahrens, P. Boffetta, A. Mukeria, 2001, Cancer research.

Molecular cloning of a cDNA encoding an inducible calmodulin-dependent nitric-oxide synthase from rat liver and its expression in COS 1 cells.

H. Kawasaki, T. Sugimura, H. Esumi, 1993, European journal of biochemistry.

Suppression of thymic lymphomas and increased nonthymic lymphomagenesis in Trp53‐deficient mice lacking inducible nitric oxide synthase gene

L. Donehower, H. Ohgaki, H. Tazawa, 2004, International journal of cancer.

Occurrence, formation and precursors of N-nitroso compounds in the Japanese diet.

H. Tokiwa, H. Ohshima, M. Matsui, 1980, IARC scientific publications.

Occurrence of volatile nitrosamines in food samples collected in three high-risk areas for nasopharyngeal carcinoma.

H. Bartsch, G. de‐Thé, H. Ohshima, 1987, IARC scientific publications.

Nitric oxide prevents UV-induced phosphorylation of the p53 tumor-suppressor protein at serine 46: a possible role in inhibition of apoptosis.

H. Ohshima, M. Tatemichi, K. Fukunaga, 2003, Biochemical and biophysical research communications.

Analysis of urinary 8-nitroguanine, a marker of nitrative nucleic acid damage, by high-performance liquid chromatography-electrochemical detection coupled with immunoaffinity purification: association with cigarette smoking.

T. Akaike, H. Ohshima, A. Barbin, 2006, Free radical biology & medicine.

Cytotoxicity and Site-specific DNA Damage Induced by Nitroxyl Anion (NO−) in the Presence of Hydrogen Peroxide

H. Ohshima, S. Oikawa, S. Kawanishi, 1999, The Journal of Biological Chemistry.

Formation of 8-nitroguanine by the reaction of guanine with peroxynitrite in vitro.

H. Ohshima, M. Becchi, H Ohshima, 1995, Carcinogenesis.

Structural basis of the genotoxicity of nitrosatable phenols and derivatives present in smoked food products.

H S Rosenkranz, G Klopman, H. Rosenkranz, 1990, Mutation research.

Synergistic induction of DNA strand breakage by cigarette tar and nitric oxide.

H. Ohshima, Y. Yoshie, 1997, Carcinogenesis.

Induction of Aberrant Crypt Foci in the Large Intestine of F344 Rats by Oral Administration of 2‐Amino‐l‐methyl‐6‐phenylimidazo[4,5‐b]pyridine

T. Sugimura, H. Esumi, Satoru Takahashi, 1991, Japanese journal of cancer research : Gann.

Suppression of intestinal polyposis in Apc(Min/+) mice by inhibiting nitric oxide production.

H. Ohshima, B. Ahn, Hiroshi Ohshima, 2001, Cancer research.

Formation of direct-acting genotoxic substances in nitrosated smoked fish and meat products: identification of simple phenolic precursors and phenyldiazonium ions as reactive products.

H. Bartsch, H. Ohshima, M. Friesen, 1989, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Identification of products formed by reaction of 3',5'-di-O-acetyl-2'-deoxyguanosine with hypochlorous acid or a myeloperoxidase-H2O2-Cl- system.

Toshinori Suzuki, H. Ohshima, M. Friesen, 2003, Chemical research in toxicology.

Endogenously formed N-nitroso compounds and nitrosating agents in human cancer etiology.

H. Bartsch, H. Ohshima, B. Pignatelli, 1992, Pharmacogenetics.

Endogenous nitrosation of L-proline by dietary-derived nitrate.

D. Forman, H. Bartsch, H. Ohshima, 1991, Nutrition and cancer.

Oxidative DNA damage in human lymphocytes: correlations with plasma levels of alpha-tocopherol and carotenoids.

J. Cadet, T. Douki, H. Ohshima, 2000, Carcinogenesis.

Effect of systemic L-arginine administration on hemodynamics and nitric oxide release in man.

H. Esumi, T. Saruta, T. Nakaki, 1992, Japanese heart journal.

Modifications of Wild-Type p 53 Tumor Suppressor Protein Nitric Oxide Induces Conformational and Functional

P. Hainaut, H. Ohshima, S. Calmels, 2006 .

Nitric oxide induces conformational and functional modifications of wild-type p53 tumor suppressor protein.

P. Hainaut, H. Ohshima, S. Calmels, 1997, Cancer research.

Inducible nitric oxide synthase, anti-oxidant enzymes and Helicobacter pylori infection in gastritis and gastric precancerous lesions in humans

J. Estève, H. Ohshima, P. Correa, 1998, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

Epstein-Barr virus activators, mutagens and volatile nitrosamines in preserved food samples from high-risk areas for nasopharyngeal carcinoma.

H. Bartsch, A. Polack, G. Bornkamm, 1991, IARC scientific publications.

Formation of N-nitrosamines and N-nitramines by the reaction of secondary amines with peroxynitrite and other reactive nitrogen species: comparison with nitrotyrosine formation.

H. Nishino, H. Ohshima, H Nishino, 2000, Chemical research in toxicology.

Urinary excretion of nitrosamino acids and nitrate by inhabitants of high- and low-risk areas for nasopharyngeal carcinoma in southern China.

H. Bartsch, G. de Thé, H. Ohshima, 1993, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Immunolocalization of inducible nitric oxide synthase in synovium and cartilage in rheumatoid arthritis and osteoarthritis.

S. Ralston, P. K. Wright, H. Ohshima, 1997, British journal of rheumatology.

Carcinogenesis and aging. II. Modifying effect of aging on metabolism of methyl(acetoxymethyl)nitrosamine and its interaction with DNA of various tissues in rats.

V. Anisimov, L. Keefer, H. Ohshima, 1983, Carcinogenesis.

Immunohistochemical localization of inducible nitric oxide synthase and 3-nitrotyrosine in rat liver tumors induced by N-nitrosodiethylamine.

B. Han, H. Ohshima, B. Ahn, 1999, Carcinogenesis.

Dietary phenolics and betel nut extracts as modifiers of N-nitrosation in rat and man.

H. Bartsch, H. Stich, H. Ohshima, 1984, IARC scientific publications.

Novel products generated from 2'-deoxyguanosine by hypochlorous acid or a myeloperoxidase-H2O2-Cl- system: identification of diimino-imidazole and amino-imidazolone nucleosides.

Toshinori Suzuki, H. Ohshima, M. Friesen, 2002, Nucleic acids research.

Chlorination of Guanosine and Other Nucleosides by Hypochlorous Acid and Myeloperoxidase of Activated Human Neutrophils

J. Cadet, J. Ravanat, Toshinori Suzuki, 2001, The Journal of Biological Chemistry.

Induction of DNA strand breakage and base oxidation by nitroxyl anion through hydroxyl radical production.

H. Ohshima, F. Bianchini, I. Gilibert, 1999, Free radical biology & medicine.

Advances in Brief Suppression of Intestinal Polyposis in Apc Min / Mice by Inhibiting Nitric Oxide Production

H. Ohshima, B. Ahn, 2001 .

A highly sensitive LC-ESI-MS/MS method for the quantification of cholesterol ozonolysis products secosterol-A and secosterol-B after derivatization with 2-hydrazino-1-methylpyridine.

Susumu Tomono, N. Miyoshi, H. Ohshima, 2011, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Formation of cholesterol ozonolysis products through an ozone-free mechanism mediated by the myeloperoxidase-H2O2-chloride system.

Susumu Tomono, N. Miyoshi, H. Ohshima, 2009, Biochemical and biophysical research communications.

Immunohistochemical localization of an inducible form of nitric oxide synthase in various organs of rats treated with Propionibacterium acnes and lipopolysaccharide

H. Bartsch, T. Sugimura, H. Esumi, 1993, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

Epstein-Barr virus activation in Raji cells by extracts of preserved food from high risk areas for nasopharyngeal carcinoma.

H. Bartsch, G. de Thé, H. Ohshima, 1988, Carcinogenesis.

Distribution of nitric oxide synthase in the central nervous system of Macaca fuscata: subcortical regions

R. Arai, K. Kitahama, M. Narita, 1995, Neuroscience.

Direct synaptic contacts of nitric oxide synthase-immunoreactive nerve terminals on the neurons of the intracardiac ganglia of the guinea pig

H. Esumi, Koichii Tanaka, T. Chiba, 1993, Neuroscience Letters.

Gas chromatographic determination of methylguanidine, guanidine and agmatine as their hexafluoroacetylacetonates

T. Ishibashi, H. Ohshima, M. Matsui, 1977 .

Polyclonal antibody against an inducible form of nitric oxide synthase purified from the liver of rats treated with Propionibacterium acnes and lipopolysaccharide.

T. Sugimura, H. Esumi, H. Ohshima, 1992, Biochemical and biophysical research communications.

Synergistic induction of DNA strand breakage caused by nitric oxide together with catecholamine: implications for neurodegenerative disease.

H. Ohshima, Y. Yoshie, 1997, Chemical Research in Toxicology.

Purification of nitric oxide synthase from bovine brain: immunological characterization and tissue distribution.

T. Sugimura, H. Esumi, H. Ohshima, 1992, Biochemical and biophysical research communications.

Cysteine Oxidation in the Mitogenic S100B Protein Leads to Changes in Phosphorylation by Catalytic CKII-α Subunit*

J. Garin, Y. Mély, J. Baudier, 1998, The Journal of Biological Chemistry.

Urinary Markers forMeasuring Exposure toEndogenous andExogenous Alkylating Agents andPrecursors

H. Ohshima, D. Lin, V. Prévost, 1993 .

Monitoring of excreted n nitrosamino acids as a new method to quantitate endogenous nitrosation in humans

H. Bartsch, H. Ohshima, B. Pignatelli, 1983 .

Nitric oxide synthase-immunoreactive nerve fibers in the nasal mucosa of the rat

H. Esumi, Koichii Tanaka, T. Chiba, 1994, Brain Research.

Synergistic induction of DNA strand breakage by catechol-estrogen and nitric oxide: implications for hormonal carcinogenesis.

H. Ohshima, Yumiko Yoshie, Y. Yoshie, 1998, Free radical biology & medicine.

Requirement of intracellular calcium mobilization for peroxynitrite-induced poly(ADP-ribose) synthetase activation and cytotoxicity.

M. O’connor, C. Szabó, L. Virág, 1999, Molecular pharmacology.

Modification by fluoride, bromide, iodide, thiocyanate and nitrite anions of reaction of a myeloperoxidase-H2O2-Cl- system with nucleosides.

Toshinori Suzuki, H. Ohshima, 2003, Chemical & pharmaceutical bulletin.

Nitrosating properties of bis-methylthio-diiron-tetranitrosyl (Roussin's red methyl ester), a nitroso compound isolated from pickled vegetables consumed in northern China.

H. Bartsch, H. Ohshima, A. Croisy, 1984, IARC scientific publications.

Induction of Ca2+/calmodulin‐dependent NO synthase in various organs of rats by Propionibacterium acnes and lipopolysaccharide treatment

H. Esumi, H. Ohshima, S. Oguchi, 1992, FEBS letters.

Identification in rats of N-nitrosonipecotic acid as a major urinary metabolite of the areca-nut alkaloid-derived nitrosamines, N-nitrosoguvacoline and N-nitrosoguvacine.

H. Bartsch, H. Ohshima, M. Friesen, 1989, Cancer letters.

Tumorigenicity study in Syrian hamsters fed areca nut together with nitrite.

H. Bartsch, H. Ohshima, U. Mohr, 1987, Carcinogenesis.

Infection, Inflammation, and Cancer: Overview

Susumu Tomono, N. Miyoshi, H. Ohshima, 2014 .

Ingested Nitrate and Nitrite: Beneficial to Human Health?

N. Miyoshi, H. Ohshima, 2010 .

N-nitrosamine formation by microorganisms isolated from human gastric juice and urine: biochemical studies on bacteria-catalysed nitrosation.

H. Bartsch, H. Ohshima, M. Crespi, 1987, IARC scientific publications.

Formation of a diimino-imidazole nucleoside from 2'-deoxyguanosine by singlet oxygen generated by methylene blue photooxidation.

Toshinori Suzuki, H. Ohshima, M. Friesen, 2003, Bioorganic & Medicinal Chemistry.

Campylobacter pylori nancy, le 16/1/1988

B. Marshall, N. Muñoz, C. Beyaert, 2008, Acta Endoscopica.