F. Chung

发表

Induction of liver tumors in F344 rats by crotonaldehyde.

S. Hecht, T. Tanaka, F. Chung, 1986, Cancer research.

Oral cytology assessment by flow cytometry of DNA adducts, aneuploidy, proliferation and apoptosis shows differences between smokers and non-smokers.

W. Guo, J. Schwartz, J. Muscat, 2003, Oral oncology.

A Novel Mechanism of Chemoprotection by Sulforaphane

P. Karplus, F. Chung, R. Dashwood, 2004, Cancer Research.

Inhibition of Histone Deacetylase A Novel Mechanism of Chemoprotection by Sulforaphane : Updated

P. Karplus, F. Chung, R. Dashwood, 2004 .

Photoaddition of chlorpromazine to DNA.

I. Kochevar, F. Chung, A. Jeffrey, 1984, Chemico-biological interactions.

Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes and its inhibition by isothiocyanates.

P. Thomas, Chung S. Yang, F. Chung, 1990, Cancer research.

Proteins as binding targets of isothiocyanates in cancer prevention.

A. D. Di Pasqua, F. Chung, Lixin Mi, 2011, Carcinogenesis.

Urinary isothiocyanate levels and lung cancer risk among non-smoking women: a prospective investigation.

N. Rothman, X. Shu, Yu-tang Gao, 2011, Lung cancer.

Urinary isothiocyanate excretion, brassica consumption, and gene polymorphisms among women living in Shanghai, China.

X. Shu, Yu-tang Gao, W. Zheng, 2003, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Urinary isothiocyanate levels, brassica, and human breast cancer.

X. Shu, Yu-tang Gao, W. Zheng, 2003, Cancer research.

Disposition of Glucosinolates and Sulforaphane in Humans After Ingestion of Steamed and Fresh Broccoli

F. Chung, L. Liebes, C. Conaway, 2000, Nutrition and cancer.

Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms, and lung-cancer risk: a prospective study of men in Shanghai, China

G. Coetzee, S. London, Jian-Min Yuan, 2000, The Lancet.

Chemoprevention of colonic aberrant crypt foci in Fischer rats by sulforaphane and phenethyl isothiocyanate.

C. Rao, F. Chung, Bandaru S. Reddy, 2000, Carcinogenesis.

Quantitation of human uptake of the anticarcinogen phenethyl isothiocyanate after a watercress meal.

F. Chung, M. Morse, K. Eklind, 1992, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Identification and quantification of the N-acetylcysteine conjugate of allyl isothiocyanate in human urine after ingestion of mustard.

Chi-Tang Ho, C. Ho, F. Chung, 1994, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

A urinary biomarker for uptake of dietary isothiocyanates in humans.

M. Yu, F. Chung, D. Jiao, 1998, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Effects of nonsteroidal antiinflammatory drugs on oxidative pathways in A/J mice.

F. Chung, J. Bilodeau, A. Castonguay, 1995, Free radical biology & medicine.

Monoclonal Antibodies for the Detection of a Specific Cyclic DNA Adduct Derived from ω-6 Polyunsaturated Fatty Acids.

S. Amin, D. Desai, David C. H. Yang, 2018, Chemical research in toxicology.

In vivo detection of a novel endogenous etheno-DNA adduct derived from arachidonic acid and the effects of antioxidants on its formation.

S. Amin, D. Desai, Peiying Yang, 2014, Free radical biology & medicine.

Adamantyl Isothiocyanates as Mutant p53 Rescuing Agents and Their Structure-Activity Relationships.

R. Saxena, F. Chung, G. Butov, 2021, Journal of medicinal chemistry.

Reactivation of mutant p53 by a dietary-related compound phenethyl isothiocyanate inhibits tumor growth

G. Blandino, M. Avantaggiati, S. D. Agostino, 2016, Cell Death and Differentiation.

Isothiocyanates as cancer chemopreventive agents: their biological activities and metabolism in rodents and humans.

F. Chung, Yang-ming Yang, C. Conaway, 2002, Current drug metabolism.

Aldo‐keto reductase 1B10 protects human colon cells from DNA damage induced by electrophilic carbonyl compounds

Yu Cao, Xuyu Zu, F. Chung, 2017, Molecular carcinogenesis.

High-performance liquid chromatography-based determination of total isothiocyanate levels in human plasma: application to studies with 2-phenethyl isothiocyanate.

S. Hecht, J. Crowell, H. Hochster, 2001, Analytical biochemistry.

The role of protein binding in induction of apoptosis by phenethyl isothiocyanate and sulforaphane in human non-small lung cancer cells.

T. Veenstra, T. Conrads, B. Hood, 2007, Cancer research.

1,N2-propanodeoxyguanosine adducts: potential new biomarkers of smoking-induced DNA damage in human oral tissue.

F. Chung, J. Guttenplan, J. Ocando, 1998, Cancer research.

Endogenous formation and significance of 1,N2-propanodeoxyguanosine adducts.

A. Nishikawa, M. Nagao, F. Chung, 1999, Mutation research.

A solid-phase extraction/high-performance liquid chromatography-based (32)P-postlabeling method for detection of cyclic 1,N(2)-propanodeoxyguanosine adducts derived from enals.

S. Amin, F. Chung, N. Salem, 2006, Analytical biochemistry.

Nicotine-derived N-nitrosamines (TSNA) and their relevance in tobacco carcinogenesis.

S. Hecht, F. Chung, D. Hoffmann, 1991, Critical reviews in toxicology.

Effect of dietary aromatic isothiocyanates fed subsequent to the administration of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone on lung tumorigenicity in mice.

S. Amin, S. Hecht, G. Stoner, 1990, Cancer letters.

Cancer Preventive Isothiocyanates Induce Selective Degradation of Cellular α- and β-Tubulins by Proteasomes*

S. Dakshanamurthy, A. Cheema, David C. H. Yang, 2009, The Journal of Biological Chemistry.

Inhibitory effects of 2-mercaptoethane sulfonate and 6-phenylhexyl isothiocyanate on urinary bladder tumorigenesis in rats induced by N-butyl-N-(4-hydroxybutyl)nitrosamine.

A. Nishikawa, F. Chung, M. Morse, 2003, Cancer letters.

Oxidative stress and hepatocarcinogenesis

F. Chung, Ying Fu, 2018, Hepatoma research.

The major lipid peroxidation product, trans-4-hydroxy-2-nonenal, preferentially forms DNA adducts at codon 249 of human p53 gene, a unique mutational hotspot in hepatocellular carcinoma.

M. Tang, S. Amin, Wenwei Hu, 2002, Carcinogenesis.

Cigarette smoking and adenocarcinoma of the lung: The relevance of nicotine-derived N-nitrosamines

S. Amin, S. Hecht, F. Chung, 1993 .

Effect of CpG methylation at different sequence context on acrolein- and BPDE-DNA binding and mutagenesis.

W. Rom, M. Tang, Xue-Ru Wu, 2013, Carcinogenesis.

Chemopreventive potential of thiol conjugates of isothiocyanates for lung cancer and a urinary biomarker of dietary isothiocyanates

Mimi C. Yu, Chung S. Yang, F. Chung, 1997, Journal of cellular biochemistry. Supplement.

Effect of Carcinogenic Acrolein on DNA Repair and Mutagenic Susceptibility*

M. Tang, Xue-Ru Wu, L. Gu, 2012, The Journal of Biological Chemistry.

Carcinogen biomarkers related to smoking and upper aerodigestive tract cancer

S. Hecht, F. Chung, S. Murphy, 1993, Journal of cellular biochemistry. Supplement.

Relevance of Nicotine-Derived N-Nitrosamines in Tobacco Carcino-Genesis

S. Hecht, F. Chung, D. Hoffmann, 1991 .

Toxicology Nicotine-Derived N-Nitrosamines (TSNA) and Their Relevance In Tobacco Carci nogenesis

S. Hecht, F. Chung, D. Hoffmann, 1991 .

Repair kinetics of acrolein- and (E)-4-hydroxy-2-nonenal-derived DNA adducts in human colon cell extracts.

R. Roy, F. Chung, S. Choudhury, 2013, Mutation research.

Repair kinetics of trans-4-hydroxynonenal-induced cyclic 1,N2-propanodeoxyguanine DNA adducts by human cell nuclear extracts.

S. Amin, R. Roy, F. Chung, 2004, Biochemistry.

Effects of alkyl chain length on the inhibition of NNK-induced lung neoplasia in A/J mice by arylalkyl isothiocyanates.

S. Amin, S. Hecht, F. Chung, 1989, Carcinogenesis.

Carcinogenicity of acrolein, crotonaldehyde, and arecoline.

P. Vineis, K. Guyton, Y. Grosse, 2020, The Lancet. Oncology.

Ingestion of an isothiocyanate metabolite from cruciferous vegetables inhibits growth of human prostate cancer cell xenografts by apoptosis and cell cycle arrest.

Longgui Wang, F. Chung, Hongyan Wu, 2004, Carcinogenesis.

Urinary Isothiocyanates; Glutathione S-Transferase M1, T1, and P1 Polymorphisms; and Risk of Colorectal Cancer: The Multiethnic Cohort Study

B. Henderson, L. Kolonel, L. Le Marchand, 2009, Cancer Epidemiology Biomarkers & Prevention.

Modulation of growth of human prostate cancer cells by the N-acetylcysteine conjugate of phenethyl isothiocyanate.

S. Amin, T. Ahmed, F. Chung, 2000, International journal of oncology.

Conversion of glucosinolates to isothiocyanates in humans after ingestion of cooked watercress.

F. Chung, S. Getahun, Serkadis M. Getahun, 1999, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Decomposition rates of isothiocyanate conjugates determine their activity as inhibitors of cytochrome p450 enzymes.

S. Amin, F. Chung, J. Krzemiński, 2001, Chemical research in toxicology.

Selective depletion of mutant p53 by cancer chemopreventive isothiocyanates and their structure-activity relationships.

Yuehua Mao, R. Fine, Y. Tomita, 2011, Journal of medicinal chemistry.

Synthesis of (-)-[4-3H]epigallocatechin gallate and its metabolic fate in rats after intravenous administration.

S. Amin, D. Desai, F. Nanjo, 2001, Journal of agricultural and food chemistry.

Isothiocyanate exposure, glutathione S-transferase polymorphisms, and colorectal cancer risk.

N. Rothman, X. Shu, Y. Xiang, 2010, The American journal of clinical nutrition.

Detection in vivo of a Novel Endogenous Etheno DNA Adduct Derived from Arachidonic Acid and the Effects of Antioxidants on Its Formation

S. Amin, D. Desai, F. Chung, 2014 .

1,N2-ethenodeoxyguanosine as a potential marker for DNA adduct formation by trans-4-hydroxy-2-nonenal.

F. Chung, R. Sodum, 1988, Cancer research.

Effects of Epigallocatechin Gallate, L-Ascorbic Acid, α-Tocopherol, and Dihydrolipoic Acid on the Formation of Deoxyguanosine Adducts Derived From Lipid Peroxidation

F. Chung, R. Nath, M. Wu, 2010, Nutrition and cancer.

Endogenous production of DNA adducts.

F. Chung, D. Li, K. Randerath, 1996, Regulatory toxicology and pharmacology : RTP.

Urinary Total Isothiocyanates and Colorectal Cancer: A Prospective Study of Men in Shanghai, China

Jian-Min Yuan, D. J. Van Den Berg, Renwei Wang, 2008, Cancer Epidemiology Biomarkers & Prevention.

Green tea and leukoplakia

J. Shah, W. Blot, A. Huvos, 1997 .

Urinary total isothiocyanate (ITC) in a population-based sample of middle-aged and older Chinese in Singapore: relationship with dietary total ITC and glutathione S-transferase M1/T1/P1 genotypes.

G. Coetzee, J. Hankin, Mimi C. Yu, 1998, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice.

Chung S. Yang, E. Wang, F. Chung, 1993, Carcinogenesis.

Sulforaphane prevents microcystin-LR-induced oxidative damage and apoptosis in BALB/c mice.

Lirong Song, F. Chung, Lixin Mi, 2011, Toxicology and applied pharmacology.

N-acetylcysteine conjugate of phenethyl isothiocyanate enhances apoptosis in growth-stimulated human lung cells.

F. Traganos, F. Chung, M. Jhanwar-Uniyal, 2005, Cancer research.

Covalent Binding to Tubulin by Isothiocyanates

T. Veenstra, T. Conrads, Zhen Xiao, 2006, Journal of Biological Chemistry.

2,3-epoxy-4-hydroxynonanal as a potential tumor-initiating agent of lipid peroxidation.

A. Nishikawa, F. Chung, J. Guttenplan, 1993, Carcinogenesis.

Effects of butylated hydroxyanisole on the tumorigenicity and metabolism of N-nitrosodimethylamine and N-nitrosopyrrolidine in A/J mice.

S. Hecht, F. Chung, S. Carmella, 1986, Cancer research.

Structural characterization of adducts formed in the reaction of 2,3-epoxy-4-hydroxynonanal with deoxyguanosine.

F. Chung, R. Sodum, 1989, Chemical research in toxicology.

Detection of exocyclic 1,N2-propanodeoxyguanosine adducts as common DNA lesions in rodents and humans.

F. Chung, R. Nath, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Detection and quantification of 1,N(6)-ethenoadenine in human placental DNA by mass spectrometry.

F. Chung, L. Zhang, L. Chiang, 1999, Chemical research in toxicology.

Epoxidation of trans-4-hydroxy-2-nonenal by fatty acid hydroperoxides and hydrogen peroxide.

H. C. Chen, F. Chung, H. J. Chen, 1996, Chemical research in toxicology.

Stereoselective formation of in vitro nucleic acid adducts by 2,3-epoxy-4-hydroxynonanal.

F. Chung, R. Sodum, 1991, Cancer research.

Inhibition of the Tobacco‐Specific Nitrosamine‐Induced Lung Tumorigenesis by Compounds Derived from Cruciferous Vegetables and Green Tea a

F. Chung, Y. Xu, M. Morse, 1993, Annals of the New York Academy of Sciences.

Total Isothiocyanate Contents in Cooked Vegetables Frequently Consumed in Singapore

J. Hankin, Mimi C. Yu, F. Chung, 1998 .

Detection of a lipid peroxidation-induced DNA adduct across liver disease stages.

B. Kallakury, K. Makambi, F. Chung, 2018, Hepatobiliary surgery and nutrition.

Regioselective formation of acrolein-derived cyclic 1,N(2)-propanodeoxyguanosine adducts mediated by amino acids, proteins, and cell lysates.

F. Chung, A. Basudan, M. Dyba, 2012, Chemical research in toxicology.

Effect of frequency of isothiocyanate administration on inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced pulmonary adenoma formation in A/J mice.

S. Amin, F. Chung, M. Morse, 1992, Cancer letters.

Inhibition by phenylethyl and phenylhexyl isothiocyanate of metabolism of and DNA methylation by N-nitrosomethylamylamine in rats.

F. Chung, T. Lawson, Q. Huang, 1993, Carcinogenesis.

Effects of dietary indoles and isothiocyanates on N-nitrosodimethylamine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone alpha-hydroxylation and DNA methylation in rat liver.

S. Hecht, F. Chung, M. Wang, 1985, Carcinogenesis.

Inhibition of tobacco-specific nitrosamine 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK) tumorigenesis with aromatic isothiocyanates.

S. Hecht, F. Chung, M. Morse, 1991, IARC scientific publications.

Binding to Protein by Isothiocyanates: A Potential Mechanism for Apoptosis Induction in Human Nonsmall Lung Cancer Cells

F. Chung, Lixin Mi, 2008, Nutrition and cancer.

A six-month crossover chemoprevention clinical trial of tea in smokers and non-smokers: methodological issues in a feasibility study

C. Dash, K. Makambi, L. Adams-Campbell, 2012, BMC Complementary and Alternative Medicine.

CHEMOPREVENTION OF LUNG CANCER BY ISOTHIOCYANATES AND THEIR CONJUGATES IN A/J MOUSE

F. Chung, 2001, Experimental lung research.

Inhibition of rat liver cytochrome P450 isozymes by isothiocyanates and their conjugates: a structure-activity relationship study.

F. Chung, C. Conaway, D. Jiao, 1996, Carcinogenesis.

Inhibition of lung carcinogenesis by black tea in Fischer rats treated with a tobacco-specific carcinogen: caffeine as an important constituent.

S. Amin, C. Ho, B. Pittman, 1998, Cancer research.

The Prevention of Lung Cancer Induced by a Tobacco-Specific Carcinogen in Rodents by Green and Black Tea

F. Chung, 1999 .

Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA adduct formation and tumorigenicity in the lung of F344 rats by dietary phenethyl isothiocyanate.

S. Amin, S. Hecht, Chung-Xiou Wang, 1989, Cancer research.

Effects of indole-3-carbinol on lung tumorigenesis and DNA methylation induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and on the metabolism and disposition of NNK in A/J mice.

S. Amin, F. Chung, Susan D Lagreca, 1990, Cancer research.

Development of a monoclonal antibody-based immunoassay for cyclic DNA adducts resulting from exposure to crotonaldehyde.

S. Hecht, F. Chung, P. Foiles, 1987, Cancer Research.

Isothiocyanates inhibit proteasome activity and proliferation of multiple myeloma cells.

F. Chung, Lixin Mi, N. Gan, 2011, Carcinogenesis.

Structure-activity relationships for inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone lung tumorigenesis by arylalkyl isothiocyanates in A/J mice.

S. Amin, D. Desai, S. Hecht, 1991, Cancer research.

Detection of 1, N2-propanodeoxyguanosine adducts as potential endogenous DNA lesions in rodent and human tissues.

F. Chung, J. Ocando, R. Nath, 1996, Cancer research.

Formation of cyclic deoxyguanosine adducts in Chinese hamster ovary cells by acrolein and crotonaldehyde.

F. Chung, P. Foiles, S. Akerkar, 1990, Carcinogenesis.

32P-postlabelling with high-performance liquid chromatography for analysis of abundant DNA adducts in human tissues.

K. Hemminki, F. Chung, D. Li, 1999, IARC scientific publications.

Sulforaphane protects Microcystin-LR-induced toxicity through activation of the Nrf2-mediated defensive response.

Lirong Song, F. Chung, Lixin Mi, 2010, Toxicology and applied pharmacology.

Identification of crotonaldehyde as a hepatic microsomal metabolite formed by alpha-hydroxylation of the carcinogen N-nitrosopyrrolidine.

S. Hecht, F. Chung, M. Wang, 1988, Chemical research in toxicology.

Formation of cyclic 1,N2-propanodeoxyguanosine adducts in DNA upon reaction with acrolein or crotonaldehyde.

S. Hecht, F. Chung, R. Young, 1984, Cancer research.

Effects of watercress consumption on metabolism of a tobacco-specific lung carcinogen in smokers.

S. Hecht, F. Chung, S. Carmella, 1995, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Characterization of a glucuronide metabolite of 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and its dose-dependent excretion in the urine of mice and rats.

S. Amin, F. Chung, M. Morse, 1990, Carcinogenesis.

Rapid single-dose model for lung tumor induction in A/J mice by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and the effect of diet.

S. Amin, S. Hecht, G. Stoner, 1989, Carcinogenesis.

Effects of dietary sinigrin or indole-3-carbinol on O6-methylguanine-DNA-transmethylase activity and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA methylation and tumorigenicity in F344 rats.

S. Amin, S. Hecht, F. Chung, 1988, Carcinogenesis.

Formation of trans-4-hydroxy-2-nonenal- and other enal-derived cyclic DNA adducts from ω-3 and ω-6 polyunsaturated fatty acids and their roles in DNA repair and human p53 gene mutation

M. Tang, Wenwei Hu, R. Roy, 2003 .

Molecular and cellular effects of green tea on oral cells of smokers: a pilot study.

J. Schwartz, F. Chung, V. Baker, 2005, Molecular nutrition & food research.

Tea as Antioxidant in Prevention of Lung Cancer

F. Chung, Mingyao Wang, You Xu, 1997 .

High-throughput, Quantitative Analysis of Acrolein-derived DNA Adducts in Human Oral Cells by Immunohistochemistry

Emily J. Greenspan, F. Chung, S. Mueller, 2012, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Formation of cyclic deoxyguanosine adducts from omega-3 and omega-6 polyunsaturated fatty acids under oxidative conditions.

F. Chung, Jishen Pan, 2002, Chemical research in toxicology.

The prevention of lung cancer induced by a tobacco-specific carcinogen in rodents by green and black Tea.

F. Chung, 1999, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Dietary Isothiocyanates: Roles in Cancer Prevention and Metabolism in Rodents and Humans

F. Chung, 2002 .

Disposition and pharmacokinetics of phenethyl isothiocyanate and 6-phenylhexyl isothiocyanate in F344 rats.

F. Chung, L. Liebes, C. Conaway, 1999, Drug metabolism and disposition: the biological fate of chemicals.

The essential role of the functional group in alkyl isothiocyanates for inhibition of tobacco nitrosamine-induced lung tumorigenesis.

S. Amin, F. Chung, C. S. Yang, 1996, Carcinogenesis.

Chemopreventive Effects of 3‐Phenylpropyl Isothiocyanate on Hamster Lung Tumorigenesis Initiated with N‐Nitrosobis(2‐oxopropyl)amine

A. Nishikawa, F. Furukawa, F. Chung, 1996, Japanese journal of cancer research : Gann.

Chemopreventive effects of phenethyl isothiocyanate on lung and pancreatic tumorigenesis in N-nitrosobis(2-oxopropyl)amine-treated hamsters.

A. Nishikawa, F. Furukawa, C. Uneyama, 1996, Carcinogenesis.

Acrolein-derived DNA adduct formation in human colon cancer cells: its role in apoptosis induction by docosahexaenoic acid.

F. Chung, R. Goldman, R. Lan, 2009, Chemical research in toxicology.

Nucleotide excision repair deficiency increases levels of acrolein-derived cyclic DNA adduct and sensitizes cells to apoptosis induced by docosahexaenoic acid and acrolein.

R. Roy, F. Chung, D. Berry, 2016, Mutation research.

Theaphenon E prevents fatty liver disease and increases CD4+ T cell survival in mice fed a high-fat diet.

A. Cheema, F. Chung, E. Pannkuk, 2020, Clinical nutrition.

Inhibition of benzo(a)pyrene-induced lung tumorigenesis in A/J mice by dietary N-acetylcysteine conjugates of benzyl and phenethyl isothiocyanates during the postinitiation phase is associated with activation of mitogen-activated protein kinases and p53 activity and induction of apoptosis.

S. Amin, W. Dai, Chung-Xiou Wang, 2002, Cancer research.

Aggresome-like structure induced by isothiocyanates is novel proteasome-dependent degradation machinery.

F. Chung, Lixin Mi, N. Gan, 2009, Biochemical and biophysical research communications.

Deoxyguanosine adducts of t-4-hydroxy-2-nonenal are endogenous DNA lesions in rodents and humans: detection and potential sources.

A. Nishikawa, F. Chung, L. Zhang, 2000, Cancer research.

A/J mouse lung tumorigenesis by the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its inhibition by arylalkyl isothiocyanates.

S. Hecht, F. Chung, M. Morse, 1991, Experimental lung research.

Glutathione depletion enhances the formation of endogenous cyclic DNA adducts derived from t-4-hydroxy-2-nonenal in rat liver.

S. Amin, F. Chung, J. Richie, 2005, Chemical research in toxicology.

Deoxyguanosine adducts of tert-4-hydroxy-2-nonenal as markers of endogenous DNA lesions.

F. Chung, Lei Zhang, 2002, Methods in enzymology.

Formation of cyclic 1,N2--adducts by reaction of deoxyguanosine with alpha-acetoxy-N-nitrosopyrrolidine, 4-(carbethoxynitrosamino)butanal, or crotonaldehyde.

S. Hecht, F. Chung, S. Hecht, 1983, Cancer research.

Effects of dietary compounds on alpha-hydroxylation of N-nitrosopyrrolidine and N'-nitrosonornicotine in rat target tissues.

S. Hecht, F. Chung, J. Vitarius, 1984, Cancer research.

Formation of N2-tetrahydrofuranyl and N2-tetrahydropyranyl adducts in the reactions of alpha-acetoxy-N-nitrosopyrrolidine and alpha-acetoxy-N-nitrosopiperidine with DNA.

S. Hecht, F. Chung, M. Wang, 1995, Chemical research in toxicology.

Reactions of alpha-acetoxy-N-nitrosopyrrolidine and alpha-acetoxy-N-nitrosopiperidine with deoxyguanosine: formation of N2-tetrahydrofuranyl and N2-tetrahydropyranyl adducts.

S. Hecht, F. Chung, M. Wang, 1995, Chemical research in toxicology.

Reaction of alpha-acetoxy-N-nitrosopiperidine with deoxyguanosine: oxygen-dependent formation of 4-oxo-2-pentenal and a 1,N2-ethenodeoxyguanosine adduct.

S. Hecht, F. Chung, R. Young-Sciame, 1992, Chemical research in toxicology.

Formation of acyclic and cyclic guanine adducts in DNA reacted with alpha-acetoxy-N-nitrosopyrrolidine.

S. Hecht, F. Chung, M. Wang, 1989, Chemical research in toxicology.

Detection of exocyclic guanine adducts in hydrolysates of hepatic DNA of rats treated with N-nitrosopyrrolidine and in calf thymus DNA reacted with alpha-acetoxy-N-nitrosopyrrolidine.

S. Hecht, F. Chung, M. Wang, 1989, Cancer research.

Formation of cyclic deoxyguanosine adducts from ω-3 and ω-6 polyunsaturated fatty acids under oxidative conditions

F. Chung, Jishen Pan, 2002 .

Role of 1,N2-propanodeoxyguanosine adducts as endogenous DNA lesions in rodents and humans.

F. Chung, L. Zhang, J. Ocando, 1999, IARC scientific publications.

Increased 8-oxodeoxyguanosine levels in lung DNA of A/J mice and F344 rats treated with the tobacco-specific nitrosamine 4-(methylnitrosamine)-1-(3-pyridyl)-1-butanone.

F. Chung, Y. Xu, Yong Xu, 1992, Carcinogenesis.

Dietary Phenethyl Isothiocyanate Adduct Formation and Tumorigenicity in the Lung of F 344 Rats 4-( Methylnitrosamino )-1-( 3-pyridyl )-1-butanone-induced DNA Inhibition of Updated

S. Amin, S. Hecht, F. Chung, 2006 .

Inhibition of tobacco-specific nitrosamine 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumors and DNA methylation in F344 rats and A/J mice by phenethyl isothiocyanate.

S. Hecht, F. Chung, M. Morse, 1990, Basic life sciences.

Formation of trans-4-hydroxy-2-nonenal- and other enal-derived cyclic DNA adducts from omega-3 and omega-6 polyunsaturated fatty acids and their roles in DNA repair and human p53 gene mutation.

M. Tang, Wenwei Hu, R. Roy, 2003, Mutation research.

A Study of Reactions of α,β-Unsaturated Carbonyl Compounds with Deoxyguanosine

S. Hecht, F. Chung, K. R. Roy, 1988 .

Effect of glutathione depletion on exocyclic adduct levels in the liver DNA of F344 rats.

F. Chung, J. Richie, J. Ocando, 1997, Chemical research in toxicology.

General route for the facile synthesis of pyrimidin-2-one-4-thione derivatives via the annulation of cyclic o-aminonitriles using carbonyl sulfide

F. Chung, R. Earl, L. Townsend, 1981 .

Synthesis of certain [6:5:6] linear tricyclic nucleosides as potential antitumor agents.

F. Chung, R. Earl, L. Townsend, 1980, Journal of medicinal chemistry.

New potential chemopreventive agents for lung carcinogenesis of tobacco-specific nitrosamine.

F. Chung, M. Morse, K. Eklind, 1992, Cancer research.

Effects of aromatic isothiocyanates on tumorigenicity, O6-methylguanine formation, and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung.

S. Amin, S. Hecht, F. Chung, 1989, Cancer research.

REDUCTIVE DEBROMINATION OF SOME PURINE AND PURINE-LIKE NUCLEOSIDES

F. Chung, R. Earl, L. Townsend, 1980 .

Gr upSM Clinicopathologic Risk Factors and Biomarkers Associated with Recurrence in Patients after Curative Resection of Hepatocellular Carcinoma

F. Chung, Ying Fu, Coleman I. Smith, 2016 .

Mechanisms of chronic disease causation by nutritional factors and tobacco products and their prevention by tea polyphenols.

J H Weisburger, F. Chung, J. Weisburger, 2002, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Isothiocyanates suppress the invasion and metastasis of tumors by targeting FAK/MMP-9 activity

Young-Chae Chang, Cheorl-Ho Kim, Kwan-Kyu Park, 2017, Oncotarget.

Targeting cell cycle machinery as a molecular mechanism of sulforaphane in prostate cancer prevention.

Longgui Wang, T. Ahmed, F. Chung, 2004, International journal of oncology.

Sulforaphane and its metabolite mediate growth arrest and apoptosis in human prostate cancer cells.

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Formation of cyclic nucleic acid adducts from some simple alpha, beta-unsaturated carbonyl compounds and cyclic nitrosamines.

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A Click Chemistry Approach to Identify Protein Targets of Cancer Chemopreventive Phenethyl Isothiocyanate.

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Isothiocyanates suppress the invasion and metastasis of tumors by targeting FAK/MMP-9 activity.

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