Weimei Sun

发表

Synthesis and Reactivity of Spirocarbocycles as Scaffolds for Nucleoside Analogues.

F. De Proft, V. Pande, Jonas Verhoeven, 2020, The Journal of organic chemistry.

Abstract DDT02-04: A novel PRMT5 inhibitor with potent in vitro and in vivo activity in preclinical lung cancer models

Italo Poggesi, Vineet Pande, James P. Edwards, 2017 .

Targeting Enteropeptidase with Reversible Covalent Inhibitors To Achieve Metabolic Benefits

Jiejun Wu, M. Cummings, Xuqing Zhang, 2020, The Journal of Pharmacology and Experimental Therapeutics.

A Chemical Probe for the Methyl Transferase PRMT5 with a Novel Binding Mode.

V. Pande, D. Brehmer, M. Paradé, 2020, ACS medicinal chemistry letters.

Discovery and Pharmacological Characterization of JNJ-64619178, a Novel Small-Molecule Inhibitor of PRMT5 with Potent Antitumor Activity

Bie M. P. Verbist, U. Philippar, T. Graubert, 2021, Molecular Cancer Therapeutics.

Preparation of 4'-Spirocyclobutyl Nucleoside Analogues as Novel and Versatile Adenosine Scaffolds.

V. Pande, Jonas Verhoeven, Weimei Sun, 2019, Chemistry.

Discovery of a novel series of guanidinebenzoates as gut-restricted enteropeptidase and trypsin dual inhibitors for the treatment of metabolic syndrome.

M. Cummings, Xuqing Zhang, Weimei Sun, 2021, Bioorganic & Medicinal Chemistry Letters.

Optimization of a pyrazole hit from FBDD into a novel series of indazoles as ketohexokinase inhibitors.

A. Gibbs, L. Kuo, Z. Sui, 2011, Bioorganic & medicinal chemistry letters.

Abstract 5690: Discovery of JNJ-67856633: A novel, first-in-class MALT1 protease inhibitor for the treatment of B cell lymphomas

J. Edwards, G. Vanhoof, U. Philippar, 2020, Cancer Chemistry.

Discovery and optimization of a series of small-molecule allosteric inhibitors of MALT1 protease.

J. Edwards, Tianbao Lu, U. Philippar, 2019, Bioorganic & medicinal chemistry letters.