K. Hübel

发表

Natural product-inspired cascade synthesis yields modulators of centrosome integrity.

A. Hyman, A. Bird, S. Grimme, 2012, Nature chemical biology.

The development of a whole-cell based medium throughput screening system for the discovery of human aldosterone synthase (CYP11B2) inhibitors: Old drugs disclose new applications for the therapy of congestive heart failure, myocardial fibrosis and hypertension

H. Waldmann, K. Hübel, R. Bernhardt, 2011, The Journal of Steroid Biochemistry and Molecular Biology.

Development of test systems for the discovery of selective human aldosterone synthase (CYP11B2) and 11β-hydroxylase (CYP11B1) inhibitors. Discovery of a new lead compound for the therapy of congestive heart failure, myocardial fibrosis and hypertension

K. Hübel, R. Bernhardt, M. Bureik, 2004, Molecular and Cellular Endocrinology.

Prieurianin/endosidin 1 is an actin-stabilizing small molecule identified from a chemical genetic screen for circadian clock effectors in Arabidopsis thaliana.

P. Hussey, H. Waldmann, G. Coupland, 2012, The Plant journal : for cell and molecular biology.

A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis

M. Greenberg, A. Draguhn, M. Rehmsmeier, 2009, Nature Cell Biology.

Identification of thiazolidinones spiro-fused to indolin-2-ones as potent and selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase B.

S. Grimme, H. Waldmann, K. Hübel, 2010, Angewandte Chemie.

Chemical biology--identification of small molecule modulators of cellular activity by natural product inspired synthesis.

Herbert Waldmann, H. Waldmann, K. Hübel, 2008, Chemical Society reviews.

The human mineralocorticoid receptor only partially differentiates between different ligands after expression in fission yeast.

K. Hübel, R. Bernhardt, M. Bureik, 2005, FEMS yeast research.

The Ras pathway modulator melophlin A targets dynamins.

H. Waldmann, D. Manstein, M. Kaiser, 2009, Angewandte Chemie.

ATP competitive inhibitors of D-alanine-D-alanine ligase based on protein kinase inhibitor scaffolds.

Stefan Wetzel, Herbert Waldmann, Daniel Rauh, 2009, Bioorganic & medicinal chemistry.

Identification and further development of thiazolidinones spiro-fused to indolin-2-ones as potent and selective inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B

H. Waldmann, K. Hübel, D. Rauh, 2011 .