A. McArdle

G. Kemp, R. Griffiths, F. McArdle, 2007, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Skeletal Muscle Contractions Induce Acute Changes in Cytosolic Superoxide, but Slower Responses in Mitochondrial Superoxide and Cellular Hydrogen Peroxide

M. Jackson, J. Chamberlain, A. McArdle, 2014, PloS one.

Release of reactive oxygen and nitrogen species from contracting skeletal muscle cells. Free Radic. Biol. Med. 37:1064–1072; 2004

M. Jackson, J. Morgan, A. McArdle, 2004 .

Release of reactive oxygen and nitrogen species from contracting skeletal muscle cells.

M. Jackson, J. Morgan, A. McArdle, 2004, Free radical biology & medicine.

Effects of contractile activity on muscle damage in the dystrophin-deficient mdx mouse.

R. Edwards, M. Jackson, A. McArdle, 1991, Clinical science.

Hyperthermia to normal human skin in vivo upregulates heat shock proteins 27, 60, 72i and 90

L. Rhodes, M. Jackson, C. Foster, 2000, Journal of cutaneous pathology.

Accumulation of calcium by normal and dystrophin-deficient mouse muscle during contractile activity in vitro.

R. Edwards, M. Jackson, A. McArdle, 1992, Clinical science.

Time course of changes in plasma membrane permeability in the dystrophin‐deficient mdx mouse

R. Edwards, M. Jackson, A. McArdle, 1994, Muscle & nerve.

longus muscles of rats: the role of vitamin E Contraction-induced injury to the extensor digitorum

J. Faulkner, M. Jackson, A. McArdle, 2015 .

Effect of propylthiouracil-induced hypothyroidism on the onset of skeletal muscle necrosis in dystrophin-deficient mdx mice.

T. Helliwell, G. Beckett, M. Catapano, 1998, Clinical science.

Contraction-induced injury to the extensor digitorum longus muscles of rats: the role of vitamin E.

J. Faulkner, M. Jackson, A. McArdle, 1997, Journal of applied physiology.

Release of creatine kinase and prostaglandin E2 from regenerating skeletal muscle fibers.

R. Edwards, M. Jackson, A. McArdle, 1994, Journal of applied physiology.

Muscle damage in mdx mice

D. Jones, R. Edwards, M. Jackson, 1991, Nature.

Accelerated sarcopenia in Cu/Zn superoxide dismutase knockout mice.

J. Faulkner, M. Jackson, A. Richardson, 2019, Free radical biology & medicine.

Damage to developing mouse skeletal muscle myotubes in culture: protective effect of heat shock proteins

A. McArdle, A. Vasilaki, M. Jackson, 2003, The Journal of physiology.

Heat shock protein 70 expression in skeletal muscle.

A. McArdle, M. Jackson, 1996, Biochemical Society transactions.

Skeletal Muscle Structure and Function Free Radical Production by Skeletal Muscle during Non- Damaging Exercise Studies of Skeletal Muscle Damage and Adaptation at the University of Liverpool the Journal of the British Society for Research on Ageing

A. McArdle, 2022 .

Investigation by polymerase chain reaction of enteroviral infection in patients with chronic fatigue syndrome.

R. Edwards, F. McArdle, M. Jackson, 1996, Clinical science.

Neuron‐specific deletion of CuZnSOD leads to an advanced sarcopenic phenotype in older mice

M. Jackson, A. Richardson, A. McArdle, 2020, Aging cell.

The effect of lengthening contractions on neuromuscular junction structure in adult and old mice

M. Jackson, A. McArdle, K. Goljanek-Whysall, 2016, AGE.

A fluorescence-based method for measuring nitric oxide in extracts of skeletal muscle.

S. Salmons, J. Jarvis, A. McArdle, 2001, Nitric oxide : biology and chemistry.

Ischaemic preconditioning of skeletal muscle 2. Investigation of the potential mechanisms involved.

L. Klenerman, I. Grierson, M. Jackson, 2002, The Journal of bone and joint surgery. British volume.

Ischemia and reperfusion of skeletal muscle lead to the appearance of a stable lipid free radical in the circulation.

R. Griffiths, M. Jackson, A. McArdle, 2003, American journal of physiology. Heart and circulatory physiology.

In vivo microdialysis—A technique for analysis of chemical activators of muscle pain

R. Edwards, M. Jackson, A. McArdle, 1999, Muscle & nerve.

Aging increases the oxidation of dichlorohydrofluorescein in single isolated skeletal muscle fibers at rest, but not during contractions

M. Jackson, A. McArdle, J. Palomero, 2013, American journal of physiology. Regulatory, integrative and comparative physiology.

Adaptive responses of mouse skeletal muscle to contractile activity: The effect of age

F. McArdle, A. McArdle, A. Vasilaki, 2006, Mechanisms of Ageing and Development.

The Exercise-Induced Stress Response of Skeletal Muscle, with Specific Emphasis on Humans

B. Drust, A. McArdle, J. Morton, 2009, Sports medicine.

Enhanced recovery from contraction-induced damage in skeletal muscles of old mice following treatment with the heat shock protein inducer 17-(allylamino)-17-demethoxygeldanamycin.

M. Jackson, A. McArdle, G. Close, 2008, Rejuvenation research.

Gathering insights on disease etiology from gene expression profiles of healthy tissues

João Pedro de Magalhães, A. Sofia Silva, Shona H. Wood, 2011, Bioinform..

Senescence in the aging process

R. Faragher, A. McArdle, E. Ostler, 2017, F1000Research.

Overexpression of HSP70 in mouse skeletal muscle protects against muscle damage and age‐related muscle dysfunction

R. Mestril, A. McArdle, Wolfgang H. Dillmann, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Exogenous glutamine: The clinical evidence

R. Griffiths, A. McArdle, T. Bongers, 2007, Critical care medicine.

A new mouse model of frailty: the Cu/Zn superoxide dismutase knockout mouse

S. Espinoza, M. Jackson, A. Richardson, 2017, GeroScience.

SS-31 attenuates TNF-α induced cytokine release from C2C12 myotubes

R. Griffiths, F. McArdle, M. Jackson, 2015, Redox biology.

Exercise and skeletal muscle ageing: cellular and molecular mechanisms

M. Jackson, A. McArdle, A. Vasilaki, 2002, Ageing Research Reviews.

Microdialysis studies of extracellular reactive oxygen species in skeletal muscle: factors influencing the reduction of cytochrome c and hydroxylation of salicylate.

M. Jackson, A. McArdle, G. Close, 2005, Free radical biology & medicine.

In vivo model of muscle pain: Quantification of intramuscular chemical, electrical, and pressure changes associated with saline-induced muscle pain in humans

L. Arendt-Nielsen, M. Jackson, A. McArdle, 1997, Pain.

Effect of xanthine oxidase-generated extracellular superoxide on skeletal muscle force generation

J. Viña, M. Gómez-Cabrera, A. McArdle, 2009, American journal of physiology. Regulatory, integrative and comparative physiology.

The emerging role of free radicals in delayed onset muscle soreness and contraction-induced muscle injury.

A. McArdle, G. Close, T. Ashton, 2005, Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.

Oxidative stress in skeletal muscle: Unraveling the potential beneficial and deleterious roles of reactive oxygen species

M. Jackson, C. Stretton, A. McArdle, 2020 .

Free Radicals, Muscle Fatigue and Damage

M. Jackson, A. McArdle, S. O'Farrell, 1995 .

Role of reactive oxygen species in age‐related neuromuscular deficits

M. Jackson, A. McArdle, A. Mcardle, 2016, The Journal of physiology.

Muscle in defense

R. Griffiths, A. McArdle, Adam P Lightfoot, 2009, Critical care medicine.

How does dystrophin deficiency lead to muscle degeneration? — Evidence from the MDX mouse

M. Jackson, A. McArdle, Rachel Edwards, 1995, Neuromuscular Disorders.

The role of hormones, cytokines and heat shock proteins during age-related muscle loss.

R. Griffiths, A. McArdle, Claire E. Lee, 2007, Clinical nutrition.

Skeletal Muscle Damage with Exercise and Aging

A. McArdle, G. Close, A. Vasilaki, 2005, Sports medicine.

Fasting increases the extent of muscle necrosis in the mdx mouse.

T. Helliwell, R. Edwards, M. Jackson, 1996, Clinical science.

depress myofibrillar force in murine skeletal muscle acts via TNFR1 and muscle-derived oxidants to

K. Campbell, J. Widrick, J. Moylan, 2015 .

Reactive Oxygen Species Generation and Skeletal Muscle Wasting – Implications for Sarcopenia

M. Jackson, A. McArdle, A. Mcardle, 2011 .

The effects of L-NAME on neuronal NOS and SOD1 expression in the DRG-spinal cord network of axotomised Thy 1.2 eGFP mice.

R. Morris, M. Jackson, A. McArdle, 2011, Neuron glia biology.

Interactions of Short-Term and Chronic Treadmill Training With Aging of the Left Ventricle of the Heart

K. Rostron, A. McArdle, R. Walton, 2015, The journals of gerontology. Series A, Biological sciences and medical sciences.

following acute nondamaging treadmill exercise heat shock protein families in human skeletal muscle Time course and differential responses of the major

Alan J. Metcalfe, S. Powers, B. Drust, 2015 .

Aberrant redox signalling and stress response in age-related muscle decline: Role in inter- and intra-cellular signalling.

M. Jackson, A. McArdle, N. Pollock, 2019, Free radical biology & medicine.

The role of attenuated redox and heat shock protein responses in the age-related decline in skeletal muscle mass and function.

M. Jackson, A. McArdle, A. Mcardle, 2017, Essays in biochemistry.

Intracellular generation of reactive oxygen species by contracting skeletal muscle cells.

F. McArdle, M. Jackson, A. McArdle, 2005, Free radical biology & medicine.

Lifelong training preserves some redox-regulated adaptive responses after an acute exercise stimulus in aged human skeletal muscle.

W. Fraser, M. Jackson, W. Gregson, 2014, Free radical biology & medicine.

Denervated muscle fibers induce mitochondrial peroxide generation in neighboring innervated fibers: Role in muscle aging

M. Jackson, A. McArdle, A. Vasilaki, 2017, Free radical biology & medicine.

Skeletal muscle transcriptomics identifies common pathways in nerve crush injury and ageing

A. McArdle, R. Barrett-Jolley, A. Vasilaki, 2022, Skeletal muscle.

Absence of insulin signalling in skeletal muscle is associated with reduced muscle mass and function: evidence for decreased protein synthesis and not increased degradation

C. Kahn, H. Remmen, M. Jackson, 2010, AGE.

Role of nerve–muscle interactions and reactive oxygen species in regulation of muscle proteostasis with ageing

M. Jackson, A. Richardson, A. McArdle, 2017, The Journal of physiology.

Workshop report: Can an understanding of the mechanisms underlying age-related loss of muscle mass and function guide exercise and other intervention strategies?

Anne McArdle, Malcolm J Jackson, Aphrodite Vasilaki, 2012, Longevity & healthspan.

fibers during development increased force generation by rat diaphragm muscle Selected Contribution: Mechanisms underlying

H. Remmen, C. Mantilla, G. Sieck, 2015 .

Discriminatory cytokine profiles predict muscle function, fatigue and cognitive function in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

A. Gusnanto, A. McArdle, M. Fenech, 2020, medRxiv.

Reduced carbohydrate availability does not modulate training-induced heat shock protein adaptations but does upregulate oxidative enzyme activity in human skeletal muscle.

T. Reilly, B. Drust, J. Bartlett, 2009, Journal of applied physiology.

atrophy muscle against immobilization-induced muscle Mitochondrial-targeted antioxidants protect skeletal

C. Franklin, S. Powers, A. Kavazis, 2015 .

Skeletal muscles of aged male mice fail to adapt following contractile activity.

F. McArdle, A. McArdle, A. Vasilaki, 2003, Biochemical Society transactions.

Attenuated HSP70 response in skeletal muscle of aged rats following contractile activity

Anne McArdle, Malcolm J Jackson, Aphrodite Vasilaki, 2002, Muscle & nerve.

Reliability of maximal muscle force and voluntary activation as markers of exercise-induced muscle damage

Greg Atkinson, Barry Drust, Anne McArdle, 2005, European Journal of Applied Physiology.

Preconditioning of skeletal muscle against contraction‐induced damage: the role of adaptations to oxidants in mice

F. McArdle, M. Jackson, A. McArdle, 2004, The Journal of physiology.

Deletion of Sod1 in Motor Neurons Exacerbates Age-Related Changes in Axons and Neuromuscular Junctions in Mice

A. McArdle, H. Van Remmen, Alex Richardson, 2023, eNeuro.

Deletion of Sod1 in motor neurons exacerbates age-related changes in axons and NMJs associated with premature muscle atrophy in aging mice

A. McArdle, H. Van Remmen, A. Vasilaki, 2022, bioRxiv.

Exercise training–induced gender‐specific heat shock protein adaptations in human skeletal muscle

A. McArdle, J. Morton, Kathryn Holloway, 2009, Muscle & nerve.

Acute effects of phorbol esters on the protein-synthetic rate and carbohydrate metabolism of normal and mdx mouse muscles.

R. Edwards, P. MacLennan, A. McArdle, 1991, The Biochemical journal.

Skeletal Muscle as an Endocrine organ; the effect of TNF‐alpha

R. Griffiths, F. McArdle, A. McArdle, 2010 .

Release of superoxide from skeletal muscle of adult and old mice: an experimental test of the reductive hotspot hypothesis

M. Jackson, A. McArdle, G. Close, 2007, Aging cell.

Older mice show decreased regeneration of neuromuscular junctions following lengthening contraction-induced injury

M. Jackson, A. McArdle, S. Brooks, 2023, GeroScience.

Ageing-induced changes in the redox status of peripheral motor nerves imply an effect on redox signalling rather than oxidative damage

M. Jackson, A. McArdle, B. McDonagh, 2016, Free radical biology & medicine.

Effects of cocaine on leakage of creatine kinase from skeletal muscle: in vitro and in vivo studies in mice.

A. McArdle, G. Brazeau, M. Jackson, 1995, Life sciences.

Adaptation to oxidative stress in ageing

M. Jackson, A. McArdle, S. Spiers, 2001, BioFactors.

Effects of whey and soy protein supplementation on inflammatory cytokines in older adults: a systematic review and meta-analysis

M. Mazidi, A. McArdle, R. Sankaranarayanan, 2022, British Journal of Nutrition.

J. Hurst, A. McArdle, K. Goljanek-Whysall, 2021, bioRxiv.

HyPer2 imaging reveals temporal and heterogeneous hydrogen peroxide changes in denervated and aged skeletal muscle fibers in vivo

M. Jackson, A. McArdle, R. Barrett-Jolley, 2019, Scientific Reports.

M. Jackson, A. McArdle, J. Palomero, 2013, Antioxidants & redox signaling.

CuZnSOD gene deletion targeted to skeletal muscle leads to loss of contractile force but does not cause muscle atrophy in adult mice

Yun Shi, M. Jackson, Yiqiang Zhang, 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Muscle in defense

R. Griffiths, A. McArdle, Adam P Lightfoot, 2009, Critical care medicine.

Understanding the origin of non-immune cell-mediated weakness in the idiopathic inflammatory myopathies – potential role of ER stress pathways

R. Cooper, K. Nagaraju, A. McArdle, 2015, Current opinion in rheumatology.

Randomised controlled trial combining vitamin E-functionalised chocolate with physical exercise to reduce the risk of protein–energy malnutrition in predementia aged people: study protocol for Choko-Age

A. McArdle, C. Mas-Bargues, J. Viña, 2023, BMJ Open.